Structural basis of elongation factor 2 switching

Fenwick, Michael K.; Ealick, Steven E.

doi:10.1016/j.crstbi.2020.02.001

Title: Structural basis of elongation factor 2 switching

Journal Article · 01 January 2020 · Current Research in Structural Biology

DOI: https://doi.org/10.1016/j.crstbi.2020.02.001 · OSTI ID:1765028

Fenwick, Michael K.;

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Sponsoring Organization:: USDOE

OSTI ID:: 1765028

Journal Information:: Current Research in Structural Biology, Journal Name: Current Research in Structural Biology Journal Issue: C Vol. 2; ISSN 2665-928X

Publisher:: ElsevierCopyright Statement

Country of Publication:: Netherlands

Language:: English

References (48)

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. Czworkowski, J.; Wang, J.; Steitz, T. A. The EMBO Journal, Vol. 13, Issue 16 https://doi.org/10.1002/j.1460-2075.1994.tb06675.x	journal	August 1994
Three-dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus. AEvarsson, A.; Brazhnikov, E.; Garber, M. The EMBO Journal, Vol. 13, Issue 16 https://doi.org/10.1002/j.1460-2075.1994.tb06676.x	journal	August 1994
UCSF Chimera?A visualization system for exploratory research and analysis Pettersen, Eric F.; Goddard, Thomas D.; Huang, Conrad C. Journal of Computational Chemistry, Vol. 25, Issue 13 https://doi.org/10.1002/jcc.20084	journal	January 2004
Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site 1 1Edited by I. A. Wilson Laurberg, Martin; Kristensen, Ole; Martemyanov, Kirill Journal of Molecular Biology, Vol. 303, Issue 4 https://doi.org/10.1006/jmbi.2000.4168	journal	November 2000
The role of guanosine 5′-triphosphate in polypeptide chain elongation Kaziro, Yoshito Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, Vol. 505, Issue 1 https://doi.org/10.1016/0304-4173(78)90009-5	journal	September 1978
The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation Kjeldgaard, Morten; Nissen, Poul; Thirup, Søren Structure, Vol. 1, Issue 1 https://doi.org/10.1016/0969-2126(93)90007-4	journal	September 1993
[20] Processing of X-ray diffraction data collected in oscillation mode Otwinowski, Zbyszek; Minor, Wladek Macromolecular Crystallography Part A, 307-326 https://doi.org/10.1016/S0076-6879(97)76066-X	book	January 1997
The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange Al-Karadaghi, Salam; Ævarsson, Arnthor; Garber, Maria Structure, Vol. 4, Issue 5 https://doi.org/10.1016/S0969-2126(96)00061-5	journal	May 1996
Structural dynamics of the ribosome Korostelev, Andrei; Ermolenko, Dmitri N.; Noller, Harry F. Current Opinion in Chemical Biology, Vol. 12, Issue 6 https://doi.org/10.1016/j.cbpa.2008.08.037	journal	December 2008
A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke Chappie, Joshua S.; Mears, Jason A.; Fang, Shunming Cell, Vol. 147, Issue 1 https://doi.org/10.1016/j.cell.2011.09.003	journal	September 2011
Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation Lin, Jinzhong; Gagnon, Matthieu G.; Bulkley, David Cell, Vol. 160, Issue 1-2 https://doi.org/10.1016/j.cell.2014.11.049	journal	January 2015
Crystal structure of a mutant elongation factor G trapped with a GTP analogue Hansson, Sebastian; Singh, Ranvir; Gudkov, Anatoly T. FEBS Letters, Vol. 579, Issue 20 https://doi.org/10.1016/j.febslet.2005.07.016	journal	July 2005
Structural Insights into Fusidic Acid Resistance and Sensitivity in EF-G Hansson, Sebastian; Singh, Ranvir; Gudkov, Anatoly T. Journal of Molecular Biology, Vol. 348, Issue 4 https://doi.org/10.1016/j.jmb.2005.02.066	journal	May 2005
Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance Pellegrino, Simone; Demeshkina, Natalia; Mancera-Martinez, Eder Journal of Molecular Biology, Vol. 430, Issue 17 https://doi.org/10.1016/j.jmb.2018.06.006	journal	August 2018
Structural Basis for Interaction of the Ribosome with the Switch Regions of GTP-Bound Elongation Factors Connell, Sean R.; Takemoto, Chie; Wilson, Daniel N. Molecular Cell, Vol. 25, Issue 5 https://doi.org/10.1016/j.molcel.2007.01.027	journal	March 2007
The Phenix software for automated determination of macromolecular structures Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor Methods, Vol. 55, Issue 1 https://doi.org/10.1016/j.ymeth.2011.07.005	journal	September 2011
The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis Fenwick, Michael K.; Dong, Min; Lin, Hening Biochemistry, Vol. 58, Issue 43 https://doi.org/10.1021/acs.biochem.9b00718	journal	September 2019
A ratchet-like inter-subunit reorganization of the ribosome during translocation Frank, Joachim; Agrawal, Rajendra Kumar Nature, Vol. 406, Issue 6793 https://doi.org/10.1038/35018597	journal	July 2000
Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome Ticu, Cristina; Nechifor, Roxana; Nguyen, Boray The EMBO Journal, Vol. 28, Issue 14 https://doi.org/10.1038/emboj.2009.169	journal	June 2009
The architecture of the spliceosomal U4/U6.U5 tri-snRNP Nguyen, Thi Hoang Duong; Galej, Wojciech P.; Bai, Xiao-chen Nature, Vol. 523, Issue 7558 https://doi.org/10.1038/nature14548	journal	June 2015
Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase Jørgensen, Rene; Ortiz, Pedro A.; Carr-Schmid, Anne Nature Structural & Molecular Biology, Vol. 10, Issue 5 https://doi.org/10.1038/nsb923	journal	April 2003
Coordinated conformational and compositional dynamics drive ribosome translocation Chen, Jin; Petrov, Alexey; Tsai, Albert Nature Structural & Molecular Biology, Vol. 20, Issue 6 https://doi.org/10.1038/nsmb.2567	journal	April 2013
Structure of EF-G–ribosome complex in a pretranslocation state Chen, Yun; Feng, Shu; Kumar, Veerendra Nature Structural & Molecular Biology, Vol. 20, Issue 9 https://doi.org/10.1038/nsmb.2645	journal	August 2013
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome Adamczyk, A. J.; Warshel, A. Proceedings of the National Academy of Sciences, Vol. 108, Issue 24 https://doi.org/10.1073/pnas.1105714108	journal	May 2011
Mutations in the G-domain of Elongation Factor G fromThermus thermophilus Affect Both Its Interaction with GTP and Fusidic Acid Martemyanov, Kirill A.; Liljas, Anders; Yarunin, Alexander S. Journal of Biological Chemistry, Vol. 276, Issue 31 https://doi.org/10.1074/jbc.M102023200	journal	August 2001
Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureus* Koripella, Ravi Kiran; Chen, Yang; Peisker, Kristin Journal of Biological Chemistry, Vol. 287, Issue 36 https://doi.org/10.1074/jbc.M112.378521	journal	August 2012
Characterization of MOCS1A, an Oxygen-sensitive Iron-Sulfur Protein Involved in Human Molybdenum Cofactor Biosynthesis Hänzelmann, Petra; Hernández, Heather L.; Menzel, Christian Journal of Biological Chemistry, Vol. 279, Issue 33 https://doi.org/10.1074/jbc.M313398200	journal	June 2004
An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2 Fabrizio, Patrizia; Laggerbauer, Bernhard; Lauber, Jürgen The EMBO Journal, Vol. 16, Issue 13 https://doi.org/10.1093/emboj/16.13.4092	journal	July 1997
Dali server: conservation mapping in 3D Holm, Liisa; Rosenstrï¿½m, Pï¿½ivi Nucleic Acids Research, Vol. 38, Issue suppl_2 https://doi.org/10.1093/nar/gkq366	journal	May 2010
The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors Macé, Kevin; Giudice, Emmanuel; Chat, Sophie Nucleic Acids Research, Vol. 46, Issue 6 https://doi.org/10.1093/nar/gky081	journal	February 2018
The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Tanzawa, Takehito; Kato, Koji; Girodat, Dylan Nucleic Acids Research, Vol. 46, Issue 6 https://doi.org/10.1093/nar/gky115	journal	February 2018
Mechanism of Elongation Factor G Function in tRNA Translocation on the Ribosome Wintermeyer, W.; Savelsbergh, A.; Semenkov, Y. P. Cold Spring Harbor Symposia on Quantitative Biology, Vol. 66, Issue 0 https://doi.org/10.1101/sqb.2001.66.449	journal	January 2001
Phaser crystallographic software McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D. Journal of Applied Crystallography, Vol. 40, Issue 4 https://doi.org/10.1107/S0021889807021206	journal	July 2007
Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid: Crystal structure of Staphylococcus aureus EF-G Chen, Yang; Koripella, Ravi Kiran; Sanyal, Suparna FEBS Journal, Vol. 277, Issue 18 https://doi.org/10.1111/j.1742-4658.2010.07780.x	journal	August 2010
The Guanine Nucleotide-Binding Switch in Three Dimensions Vetter, I. R. Science, Vol. 294, Issue 5545 https://doi.org/10.1126/science.1062023	journal	November 2001
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State Gao, Y. -G.; Selmer, M.; Dunham, C. M. Science, Vol. 326, Issue 5953 https://doi.org/10.1126/science.1179709	journal	October 2009
The Mechanism for Activation of GTP Hydrolysis on the Ribosome Voorhees, R. M.; Schmeing, T. M.; Kelley, A. C. Science, Vol. 330, Issue 6005 https://doi.org/10.1126/science.1194460	journal	November 2010
Comment on "The Mechanism for Activation of GTP Hydrolysis on the Ribosome" Liljas, A.; Ehrenberg, M.; Aqvist, J. Science, Vol. 333, Issue 6038 https://doi.org/10.1126/science.1202472	journal	June 2011
Elongation Factor G Bound to the Ribosome in an Intermediate State of Translocation Tourigny, David S.; Fernández, Israel S.; Kelley, Ann C. Science, Vol. 340, Issue 6140 https://doi.org/10.1126/science.1235490	journal	June 2013
Control of Ribosomal Subunit Rotation by Elongation Factor G Pulk, Arto; Cate, Jamie H. D. Science, Vol. 340, Issue 6140 https://doi.org/10.1126/science.1235970	journal	June 2013
Crystal Structures of EF-G–Ribosome Complexes Trapped in Intermediate States of Translocation Zhou, Jie; Lancaster, Laura; Donohue, John Paul Science, Vol. 340, Issue 6140 https://doi.org/10.1126/science.1236086	journal	June 2013
Crystal Structure of the Ternary Complex of Phe-tRNA^Phe, EF-Tu, and a GTP Analog Nissen, Poul; Kjeldgaard, Morten; Thirup, Søren Science, Vol. 270, Issue 5241, p. 1464-1472 https://doi.org/10.1126/science.270.5241.1464	journal	December 1995
Structure of a yeast spliceosome at 3.6-angstrom resolution Yan, Chuangye; Hang, Jing; Wan, Ruixue Science, Vol. 349, Issue 6253 https://doi.org/10.1126/science.aac7629	journal	August 2015
Structure of a yeast catalytic step I spliceosome at 3.4 A resolution Wan, R.; Yan, C.; Bai, R. Science, Vol. 353, Issue 6302 https://doi.org/10.1126/science.aag2235	journal	July 2016
G PROTEIN MECHANISMS:Insights from Structural Analysis Sprang, Stephen R. Annual Review of Biochemistry, Vol. 66, Issue 1 https://doi.org/10.1146/annurev.biochem.66.1.639	journal	June 1997
The Initiation of GTP Hydrolysis by the G-Domain of FeoB: Insights from a Transition-State Complex Structure Ash, Miriam-Rose; Maher, Megan J.; Guss, J. Mitchell PLoS ONE, Vol. 6, Issue 8 https://doi.org/10.1371/journal.pone.0023355	journal	August 2011
A monovalent cation acts as structural and catalytic cofactor in translational GTP ases Kuhle, Bernhard; Ficner, Ralf The EMBO Journal, Vol. 33, Issue 21 https://doi.org/10.15252/embj.201488517	journal	September 2014
Cofactor Dependent Conformational Switching of GTPases Hauryliuk, Vasili; Hansson, Sebastian; Ehrenberg, Måns Biophysical Journal, Vol. 95, Issue 4 https://doi.org/10.1529/biophysj.107.127290	journal	August 2008

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