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Title: Influence of hydrogel network microstructures on mesenchymal stem cell chondrogenesis in vitro and in vivo

Journal Article · · Acta Biomaterialia

Sponsoring Organization:
USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research
Grant/Contract Number:
2016YFB0700804
OSTI ID:
1694233
Journal Information:
Acta Biomaterialia, Journal Name: Acta Biomaterialia Vol. 91 Journal Issue: C; ISSN 1742-7061
Publisher:
ElsevierCopyright Statement
Country of Publication:
Netherlands
Language:
English

References (59)

Mechanical confinement regulates cartilage matrix formation by chondrocytes journal October 2017
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels journal March 2013
Unlike Bone, Cartilage Regeneration Remains Elusive journal November 2012
An educational review of cartilage repair: precepts & practice – myths & misconceptions – progress & prospects journal March 2015
Engineering cartilage tissue journal January 2008
Repair of Full-Thickness Cartilage Defects With Cells of Different Origin in a Rabbit Model journal February 2007
Cartilage tissue engineering for degenerative joint disease☆ journal May 2006
Comparative chondrogenesis of human cell sources in 3D scaffolds
  • Seda Tıǧlı, R.; Ghosh, Sourabh; Laha, Michael M.
  • Journal of Tissue Engineering and Regenerative Medicine, Vol. 3, Issue 5 https://doi.org/10.1002/term.169
journal July 2009
Technology Insight: adult stem cells in cartilage regeneration and tissue engineering journal July 2006
Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells journal August 2008
Material Cues as Potent Regulators of Epigenetics and Stem Cell Function journal January 2016
Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment journal May 2012
The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy journal January 2013
Nanostructured Biomaterials for Regeneration journal November 2008
Designer biomaterials for mechanobiology journal December 2017
Chondrogenesis of human bone marrow mesenchymal stem cells in 3-dimensional, photocrosslinked hydrogel constructs: Effect of cell seeding density and material stiffness journal August 2017
Immortalised human mesenchymal stem cells undergo chondrogenic differentiation in alginate and PGA/PLLA scaffolds journal May 2014
Interplay between stiffness and degradation of architectured gelatin hydrogels leads to differential modulation of chondrogenesis in vitro and in vivo journal March 2018
Differential effects of designed scaffold permeability on chondrogenesis by chondrocytes and bone marrow stromal cells journal January 2010
Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds journal July 2004
Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering journal August 2002
Scaffold Mean Pore Size Influences Mesenchymal Stem Cell Chondrogenic Differentiation and Matrix Deposition journal February 2015
The influence of scaffold microstructure on chondrogenic differentiation of mesenchymal stem cells journal May 2014
Potential of Agarose/Silk Fibroin Blended Hydrogel for in Vitro Cartilage Tissue Engineering journal August 2016
Effect of pore size on ECM secretion and cell growth in gelatin scaffold for articular cartilage tissue engineering journal February 2009
Effects of scaffold microstructure and low intensity pulsed ultrasound on chondrogenic differentiation of human mesenchymal stem cells journal November 2017
Fibrous hyaluronic acid hydrogels that direct MSC chondrogenesis through mechanical and adhesive cues journal July 2013
Chondrogenic and osteogenic differentiations of human bone marrow-derived mesenchymal stem cells on a nanofibrous scaffold with designed pore network journal October 2009
Nanofibrous hollow microspheres self-assembled from star-shaped polymers as injectable cell carriers for knee repair journal April 2011
A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells journal February 2005
Effect of chitosan scaffold microstructure on mesenchymal stem cell chondrogenesis journal April 2010
Hydrogels for the Repair of Articular Cartilage Defects journal August 2011
Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo journal September 2011
Biomimetic hydrogels for chondrogenic differentiation of human mesenchymal stem cells to neocartilage journal October 2010
Self-assembled collagen–human mesenchymal stem cell microspheres for regenerative medicine journal November 2007
An in vitro study of collagen hydrogel to induce the chondrogenic differentiation of mesenchymal stem cells journal May 2012
Chondrogenic differentiation of BMSCs encapsulated in chondroinductive polysaccharide/collagen hybrid hydrogels journal January 2017
Icariin conjugated hyaluronic acid/collagen hydrogel for osteochondral interface restoration journal July 2018
Multi-scale mechanical characterization of highly swollen photo-activated collagen hydrogels journal January 2015
Collagen I Self-Assembly: Revealing the Developing Structures that Generate Turbidity journal April 2014
Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics in vitro and in vivo journal May 2009
The role of TGFβs and Sox9 during limb chondrogenesis journal December 2006
Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis journal January 2011
Role of surface area-to-volume ratio in protein adsorption at the air–water interface journal January 2008
P hysical confinement alters cytoskeletal contributions towards human mesenchymal stem cell migration journal January 2018
Exploring and Engineering the Cell Surface Interface journal November 2005
Cytoskeletal and Focal Adhesion Influences on Mesenchymal Stem Cell Shape, Mechanical Properties, and Differentiation Down Osteogenic, Adipogenic, and Chondrogenic Pathways journal December 2012
Multiple functions of BMPs in chondrogenesis journal January 2004
The Transcription Factor Sox9 Is Involved in BMP-2 Signaling journal October 1999
Control of chondrogenesis by the transcription factor Sox9 journal June 2008
Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells journal February 2003
SOX9 Enhances Aggrecan Gene Promoter/Enhancer Activity and Is Up-regulated by Retinoic Acid in a Cartilage-derived Cell Line, TC6 journal April 2000
Chondrogenic Differentiation of Mesenchymal Stem Cells: Challenges and Unfulfilled Expectations journal December 2014
Modulation of chondrocyte functions and stiffness-dependent cartilage repair using an injectable enzymatically crosslinked hydrogel with tunable mechanical properties journal February 2014
Development of a Cellularly Degradable PEG Hydrogel to Promote Articular Cartilage Extracellular Matrix Deposition journal January 2015
The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis journal November 2004
Articular Cartilage Chondrocytes in Type I and Type II Collagen-GAG Matrices Exhibit Contractile Behavior in Vitro journal October 2000
Cross-linking affects cellular condensation and chondrogenesis in type II collagen-GAG scaffolds seeded with bone marrow-derived mesenchymal stem cells: CROSS-LINKING AFFECTS CELLULAR CONDENSATION AND CHONDROGENESIS journal March 2010
The control of chondrogenesis journal January 2005