Multicompartment Polymeric Nanoreactors for Non-Orthogonal Cascade Catalysis

Womble, C. Tyler; Kuepfert, Michael; Weck, Marcus

doi:10.1002/marc.201800580

Title: Multicompartment Polymeric Nanoreactors for Non-Orthogonal Cascade Catalysis

Journal Article · 15 October 2018 · Macromolecular Rapid Communications

DOI: https://doi.org/10.1002/marc.201800580 · OSTI ID:1657173

^[1]; Kuepfert, Michael ^[1];

^[1]

New York University, NY (United States)

Spatial confinement of multiple catalysts presents an effective strategy for performing sequential or tandem chemical transformations in a one-pot reaction. These methods may be used to catalyze numerous reactions in conditions that are otherwise incompatible between catalyst and solvent, different catalysts, or reagents. Appropriate site isolation or support structure design would lead to significant advantages in atom economy, purification, and costs and the development of the interface between a catalyst and its confined microenvironment is paramount for realizing the next-generation of nanoreactors. Polymer scaffolds can create tailor-made microenvironments resulting in catalyst compartmentalization. Through the optimization of a number of variables such as size, solubility, functionality, and morphology of the nanoreactor, catalyst activity and selectivity can be tuned. In this Feature Article, we introduce design principles and early strategies for polymer supports for catalyst site-isolation and discuss current strategies towards multi-compartment polymer nanoreactors for non-orthogonal cascade catalysis. We conclude by outlining future design trends in this burgeoning field.

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Research Organization:: Georgia Institute of Technology, Atlanta, GA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Contributing Organization:: New York University

Grant/Contract Number:: FG02-03ER15459

OSTI ID:: 1657173

Journal Information:: Macromolecular Rapid Communications, Journal Name: Macromolecular Rapid Communications Journal Issue: 1 Vol. 40; ISSN 1022-1336

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

References (90)

Dendritic Encapsulation of Function: Applying Nature's Site Isolation Principle from Biomimetics to Materials Science Hecht, Stefan; Fréchet, Jean M. J. Angewandte Chemie International Edition, Vol. 40, Issue 1 https://doi.org/10.1002/1521-3773(20010105)40:1<74::AID-ANIE74>3.0.CO;2-C	journal	January 2001
A Materials Approach to the Dual-Site Isolation of Catalysts Bonded to Linear Polymers and Small, Ionic Molecules for Use in One-Pot Cascade Reactions Miller, A. Lee; Bowden, Ned B. Advanced Materials https://doi.org/10.1002/adma.200801599	journal	September 2008
Compartmentalization Approaches in Soft Matter Science: From Nanoreactor Development to Organelle Mimics Schoonen, Lise; van Hest, Jan C. M. Advanced Materials, Vol. 28, Issue 6 https://doi.org/10.1002/adma.201502389	journal	October 2015
One-Pot Reaction Cascades Using Star Polymers with Core-Confined Catalysts Helms, Brett; Guillaudeu, Steven J.; Xie, Yu Angewandte Chemie, Vol. 117, Issue 39 https://doi.org/10.1002/ange.200502095	journal	October 2005
Expanding the Utility of One-Pot Multistep Reaction Networks through Compartmentation and Recovery of the Catalyst Phan, Nam T. S.; Gill, Christopher S.; Nguyen, Joseph V. Angewandte Chemie, Vol. 118, Issue 14 https://doi.org/10.1002/ange.200503445	journal	March 2006
Site-Isolated Base- and Acid-Mediated Michael-Initiated Cyclization Cascades Pilling, Adam W.; Boehmer, Jutta; Dixon, Darren J. Angewandte Chemie, Vol. 119, Issue 28 https://doi.org/10.1002/ange.200701079	journal	July 2007
Positional Assembly of Enzymes in Polymersome Nanoreactors for Cascade Reactions Vriezema, Dennis M.; Garcia, Paula M. L.; Sancho Oltra, Núria Angewandte Chemie, Vol. 119, Issue 39 https://doi.org/10.1002/ange.200701125	journal	October 2007
Efficient Catalytic System for the Selective Production of 5-Hydroxymethylfurfural from Glucose and Fructose Yong, Gen; Zhang, Yugen; Ying, Jackie Y. Angewandte Chemie, Vol. 120, Issue 48, p. 9485-9488 https://doi.org/10.1002/ange.200803207	journal	October 2008
Cascade Reactions in Multicompartmentalized Polymersomes Peters, Ruud J. R. W.; Marguet, Maïté; Marais, Sébastien Angewandte Chemie, Vol. 126, Issue 1 https://doi.org/10.1002/ange.201308141	journal	November 2013
Multicompartment Micelles Formed by Self-Assembly of Linear ABC Triblock Copolymers in Aqueous Medium Kubowicz, Stephan; Baussard, Jean-François; Lutz, Jean-François Angewandte Chemie International Edition, Vol. 44, Issue 33 https://doi.org/10.1002/anie.200500584	journal	August 2005
One-Pot Reaction Cascades Using Star Polymers with Core-Confined Catalysts Helms, Brett; Guillaudeu, Steven J.; Xie, Yu Angewandte Chemie International Edition, Vol. 44, Issue 39 https://doi.org/10.1002/anie.200502095	journal	October 2005
Expanding the Utility of One-Pot Multistep Reaction Networks through Compartmentation and Recovery of the Catalyst Phan, Nam T. S.; Gill, Christopher S.; Nguyen, Joseph V. Angewandte Chemie International Edition, Vol. 45, Issue 14 https://doi.org/10.1002/anie.200503445	journal	March 2006
Sequential One-Pot Reactions Using the Concept of “Site Isolation” Voit, Brigitte Angewandte Chemie International Edition, Vol. 45, Issue 26 https://doi.org/10.1002/anie.200504353	journal	June 2006
Cascade Reactions in Total Synthesis Nicolaou, K. C.; Edmonds, David J.; Bulger, Paul G. Angewandte Chemie International Edition, Vol. 45, Issue 43 https://doi.org/10.1002/anie.200601872	journal	November 2006
Site-Isolated Base- and Acid-Mediated Michael-Initiated Cyclization Cascades Pilling, Adam W.; Boehmer, Jutta; Dixon, Darren J. Angewandte Chemie International Edition, Vol. 46, Issue 28 https://doi.org/10.1002/anie.200701079	journal	July 2007
Positional Assembly of Enzymes in Polymersome Nanoreactors for Cascade Reactions Vriezema, Dennis M.; Garcia, Paula M. L.; Sancho Oltra, Núria Angewandte Chemie International Edition, Vol. 46, Issue 39 https://doi.org/10.1002/anie.200701125	journal	October 2007
Efficient Catalytic System for the Selective Production of 5-Hydroxymethylfurfural from Glucose and Fructose Yong, Gen; Zhang, Yugen; Ying, Jackie Y. Angewandte Chemie International Edition, Vol. 47, Issue 48 https://doi.org/10.1002/anie.200803207	journal	October 2008
Metal-Organic Frameworks: Opportunities for Catalysis Farrusseng, David; Aguado, Sonia; Pinel, Catherine Angewandte Chemie International Edition, Vol. 48, Issue 41 https://doi.org/10.1002/anie.200806063	journal	September 2009
Poly(2-oxazoline)s: A Polymer Class with Numerous Potential Applications Hoogenboom, Richard Angewandte Chemie International Edition, Vol. 48, Issue 43 https://doi.org/10.1002/anie.200901607	journal	October 2009
One-Pot Reactions Accelerate the Synthesis of Active Pharmaceutical Ingredients Vaxelaire, Carine; Winter, Philipp; Christmann, Mathias Angewandte Chemie International Edition, Vol. 50, Issue 16 https://doi.org/10.1002/anie.201100059	journal	March 2011
A Simple Recipe for Sophisticated Cocktails: Organocatalytic One-Pot Reactions-Concept, Nomenclature, and Future Perspectives Albrecht, Łukasz; Jiang, Hao; Jørgensen, Karl Anker Angewandte Chemie International Edition, Vol. 50, Issue 37 https://doi.org/10.1002/anie.201102522	journal	August 2011
Cascade Reactions in Multicompartmentalized Polymersomes Peters, Ruud J. R. W.; Marguet, Maïté; Marais, Sébastien Angewandte Chemie International Edition, Vol. 53, Issue 1 https://doi.org/10.1002/anie.201308141	journal	November 2013
A Three-Enzyme Cascade Reaction through Positional Assembly of Enzymes in a Polymersome Nanoreactor van Dongen, Stijn F. M.; Nallani, Madhavan; Cornelissen, Jeroen J. L. M. Chemistry - A European Journal, Vol. 15, Issue 5 https://doi.org/10.1002/chem.200802114	journal	December 2008
Highly Enantioselective Cross-Aldol Reactions of Acetaldehyde Mediated by a Dual Catalytic System Operating under Site Isolation Fan, Xinyuan; Rodríguez-Escrich, Carles; Wang, Shoulei Chemistry - A European Journal, Vol. 20, Issue 41 https://doi.org/10.1002/chem.201404215	journal	August 2014
Preparation of Polymer-Supported Ligands and Metal Complexes for Use in Catalysis Leadbeater, Nicholas E.; Marco, Maria ChemInform, Vol. 34, Issue 3 https://doi.org/10.1002/chin.200303247	journal	January 2003
Tandem Reactions, Cascade Sequences, and Biomimetic Strategies in Total Synthesis Nicolaou, K. C.; Montagnon, Tamsyn; Snyder, Scott A. ChemInform, Vol. 34, Issue 23 https://doi.org/10.1002/chin.200323226	journal	June 2003
Concepts of Nature in Organic Synthesis: Cascade Catalysis and Multistep Conversions in Concert Bruggink, Alle; Schoevaart, Rob; Kieboom, Tom ChemInform, Vol. 34, Issue 48 https://doi.org/10.1002/chin.200348270	journal	December 2003
Concurrent Tandem Catalysis Wasilke, Julia-Christina; Obrey, Stephen J.; Baker, R. Tom ChemInform, Vol. 36, Issue 26 https://doi.org/10.1002/chin.200526258	journal	June 2005
Sequential One-Pot Reactions Using the Concept of “Site Isolation” Voit, Brigitte ChemInform, Vol. 37, Issue 40 https://doi.org/10.1002/chin.200640232	journal	October 2006
Cascade Reactions in Total Synthesis Nicolaou, K. C.; Edmonds, David J.; Bulger, Paul G. ChemInform, Vol. 38, Issue 5 https://doi.org/10.1002/chin.200705218	journal	January 2007
Cross-Linked Block Copolymer Micelles: Functional Nanostructures of Great Potential and Versatility O'Reilly, Rachel K.; Hawker, Craig J.; Wooley, Karen L. ChemInform, Vol. 38, Issue 8 https://doi.org/10.1002/chin.200708237	journal	February 2007
Site-Isolated Base- and Acid-Mediated Michael-Initiated Cyclization Cascades. Pilling, Adam W.; Boehmer, Jutta; Dixon, Darren J. ChemInform, Vol. 38, Issue 44 https://doi.org/10.1002/chin.200744145	journal	October 2007
Controlled Radical Polymerization: Industrial Stakes, Obstacles and Achievements Destarac, Mathias Macromolecular Reaction Engineering, Vol. 4, Issue 3-4 https://doi.org/10.1002/mren.200900087	journal	March 2010
Advances in Atom Transfer Radical Polymerization Scholz, Carmen; Matyjaszewski, Krzysztof Polymer International, Vol. 63, Issue 5 https://doi.org/10.1002/pi.4728	journal	April 2014
Experimental Criteria for Living Polymerizations Quirk, Roderic P.; Lee, Bumjae Polymer International, Vol. 27, Issue 4 https://doi.org/10.1002/pi.4990270412	journal	January 1992
The future of reversible addition fragmentation chain transfer polymerization Barner-Kowollik, Christopher; Perrier, Sébastien Journal of Polymer Science Part A: Polymer Chemistry, Vol. 46, Issue 17 https://doi.org/10.1002/pola.22866	journal	September 2008
Aqueous-phase reforming of ethylene glycol on silica-supported metal catalysts Davda, R. R.; Shabaker, J. W.; Huber, G. W. Applied Catalysis B: Environmental, Vol. 43, Issue 1, p. 13-26 https://doi.org/10.1016/S0926-3373(02)00277-1	journal	June 2003
Tandem catalysis: a taxonomy and illustrative review Fogg, Deryn E.; dos Santos, Eduardo N. Coordination Chemistry Reviews, Vol. 248, Issue 21-24 https://doi.org/10.1016/j.ccr.2004.05.012	journal	December 2004
Silica-supported palladium: Sustainable catalysts for cross-coupling reactions Polshettiwar, Vivek; Len, Christophe; Fihri, Aziz Coordination Chemistry Reviews, Vol. 253, Issue 21-22 https://doi.org/10.1016/j.ccr.2009.06.001	journal	November 2009
Direct conversion of glucose and cellulose to 5-hydroxymethylfurfural in ionic liquid under microwave irradiation Li, Changzhi; Zhang, Zehui; Zhao, Zongbao K. Tetrahedron Letters, Vol. 50, Issue 38 https://doi.org/10.1016/j.tetlet.2009.07.053	journal	September 2009
50th Anniversary Perspective : RAFT Polymerization—A User Guide Perrier, Sébastien Macromolecules, Vol. 50, Issue 19 https://doi.org/10.1021/acs.macromol.7b00767	journal	September 2017
Acid–Base Bifunctional Shell Cross-Linked Micelle Nanoreactor for One-Pot Tandem Reaction Lee, Li-Chen; Lu, Jie; Weck, Marcus ACS Catalysis, Vol. 6, Issue 2 https://doi.org/10.1021/acscatal.5b02538	journal	January 2016
Multicomponent Catalysts: Limitations and Prospects Kumar, Gaurav; Nikolla, Eranda; Linic, Suljo ACS Catalysis, Vol. 8, Issue 4 https://doi.org/10.1021/acscatal.8b00145	journal	March 2018
Rational Approach to Polymer-Supported Catalysts: Synergy between Catalytic Reaction Mechanism and Polymer Design Madhavan, Nandita; Jones, Christopher W.; Weck, Marcus Accounts of Chemical Research, Vol. 41, Issue 9 https://doi.org/10.1021/ar800081y	journal	September 2008
Preparation of Polymer-Supported Ligands and Metal Complexes for Use in Catalysis Leadbeater, Nicholas E.; Marco, Maria Chemical Reviews, Vol. 102, Issue 10 https://doi.org/10.1021/cr010361c	journal	October 2002
Concurrent Tandem Catalysis Wasilke, Julia-Christina; Obrey, Stephen J.; Baker, R. Tom Chemical Reviews, Vol. 105, Issue 3, p. 1001-1020 https://doi.org/10.1021/cr020018n	journal	March 2005
Atom Transfer Radical Polymerization Matyjaszewski, Krzysztof; Xia, Jianhui Chemical Reviews, Vol. 101, Issue 9 https://doi.org/10.1021/cr940534g	journal	September 2001
Domino Reactions in Organic Synthesis Tietze, Lutz F. Chemical Reviews, Vol. 96, Issue 1 https://doi.org/10.1021/cr950027e	journal	January 1996
"Wolf and Lamb" reactions equilibrium and kinetic effects in multipolymer systems Cohen, B. J.; Kraus, M. A.; Patchornik, A. Journal of the American Chemical Society, Vol. 103, Issue 25 https://doi.org/10.1021/ja00415a034	journal	December 1981
Organic synthesis involving multipolymer reactions. Polymeric trityllithium Cohen, B. J.; Kraus, M. A.; Patchornik, A. Journal of the American Chemical Society, Vol. 99, Issue 12 https://doi.org/10.1021/ja00454a050	journal	June 1977
Amphiphilic Homopolymer as a Reaction Medium in Water: Product Selectivity within Polymeric Nanopockets Arumugam, Selvanathan; Vutukuri, Dharma Rao; Thayumanavan, S. Journal of the American Chemical Society, Vol. 127, Issue 38 https://doi.org/10.1021/ja051107v	journal	September 2005
Simultaneous, Segregated Storage of Two Agents in a Multicompartment Micelle Lodge, Timothy P.; Rasdal, April; Li, Zhibo Journal of the American Chemical Society, Vol. 127, Issue 50 https://doi.org/10.1021/ja056841t	journal	December 2005
Microcapsule Enabled Multicatalyst System Poe, Sarah L.; Kobašlija, Muris; McQuade, D. Tyler Journal of the American Chemical Society, Vol. 128, Issue 49 https://doi.org/10.1021/ja066476l	journal	December 2006
One-Pot Multi-Component Asymmetric Cascade Reactions Catalyzed by Soluble Star Polymers with Highly Branched Non-Interpenetrating Catalytic Cores Chi, Yonggui; Scroggins, Steven T.; Fréchet, Jean M. J. Journal of the American Chemical Society, Vol. 130, Issue 20 https://doi.org/10.1021/ja8013456	journal	May 2008
Easy Access to a Family of Polymer Catalysts from Modular Star Polymers Rodionov, Valentin; Gao, Haifeng; Scroggins, Steven Journal of the American Chemical Society, Vol. 132, Issue 8 https://doi.org/10.1021/ja9104842	journal	March 2010
Compartmentalization of Incompatible Catalytic Transformations for Tandem Catalysis Lu, Jie; Dimroth, Jonas; Weck, Marcus Journal of the American Chemical Society, Vol. 137, Issue 40 https://doi.org/10.1021/jacs.5b07257	journal	September 2015
Self-Assembly into Multicompartment Micelles and Selective Solubilization by Hydrophilic−Lipophilic−Fluorophilic Block Copolymers Marsat, Jean-Noël; Heydenreich, Matthias; Kleinpeter, Erich Macromolecules, Vol. 44, Issue 7 https://doi.org/10.1021/ma200032j	journal	April 2011
Multicompartment Block Polymer Micelles Moughton, Adam O.; Hillmyer, Marc A.; Lodge, Timothy P. Macromolecules, Vol. 45, Issue 1 https://doi.org/10.1021/ma201865s	journal	December 2011
Synthesis of Ternary, Hydrophilic−Lipophilic−Fluorophilic Block Copolymers by Consecutive RAFT Polymerizations and Their Self-Assembly into Multicompartment Micelles Skrabania, Katja; Berlepsch, Hans v.; Böttcher, Christoph Macromolecules, Vol. 43, Issue 1 https://doi.org/10.1021/ma901913f	journal	January 2010
Living Free-Radical Polymerization by Reversible Addition−Fragmentation Chain Transfer: The RAFT Process Chiefari, John; Chong, Y. K. (Bill); Ercole, Frances Macromolecules, Vol. 31, Issue 16 https://doi.org/10.1021/ma9804951	journal	August 1998
Concepts of Nature in Organic Synthesis: Cascade Catalysis and Multistep Conversions in Concert Bruggink, Alle; Schoevaart, Rob; Kieboom, Tom Organic Process Research & Development, Vol. 7, Issue 5 https://doi.org/10.1021/op0340311	journal	September 2003
Organic-functionalized molecular sieves as shape-selective catalysts Jones, Christopher W.; Tsuji, Katsuyuki; Davis, Mark E. Nature, Vol. 393, Issue 6680 https://doi.org/10.1038/29959	journal	May 1998
From precision polymers to complex materials and systems Lutz, Jean-François; Lehn, Jean-Marie; Meijer, E. W. Nature Reviews Materials, Vol. 1, Issue 5 https://doi.org/10.1038/natrevmats.2016.24	journal	April 2016
Orthogonal tandem catalysis Lohr, Tracy L.; Marks, Tobin J. Nature Chemistry, Vol. 7, Issue 6 https://doi.org/10.1038/nchem.2262	journal	May 2015
Natural strategies for the spatial optimization of metabolism in synthetic biology Agapakis, Christina M.; Boyle, Patrick M.; Silver, Pamela A. Nature Chemical Biology, Vol. 8, Issue 6 https://doi.org/10.1038/nchembio.975	journal	May 2012
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions Tan, Hongliang; Guo, Song; Dinh, Ngoc-Duy Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/s41467-017-00757-4	journal	September 2017
Integrating enzymatic and acid catalysis to convert glucose into 5-hydroxymethylfurfural Huang, Renliang; Qi, Wei; Su, Rongxin Chem. Commun., Vol. 46, Issue 7, p. 1115-1117 https://doi.org/10.1039/B921306F	journal	January 2010
Multicompartmentalized polymeric systems: towards biomimetic cellular structure and function Marguet, Maïté; Bonduelle, Colin; Lecommandoux, Sébastien Chem. Soc. Rev., Vol. 42, Issue 2 https://doi.org/10.1039/C2CS35312A	journal	January 2013
Membrane-mediated cascade reactions by enzyme–polymer proteinosomes Huang, Xin; Li, Mei; Mann, Stephen Chem. Commun., Vol. 50, Issue 47 https://doi.org/10.1039/C4CC02256D	journal	January 2014
Acid- and base-functionalized core-confined bottlebrush copolymer catalysts for one-pot cascade reactions Xiong, Linfeng; Zhang, Hui; Zhong, Aiqing Chem. Commun., Vol. 50, Issue 94 https://doi.org/10.1039/C4CC06573E	journal	January 2014
Pot economy and one-pot synthesis Hayashi, Yujiro Chemical Science, Vol. 7, Issue 2 https://doi.org/10.1039/C5SC02913A	journal	January 2016
Acid–base bifunctional amphiphilic organic nanotubes as a catalyst for one-pot cascade reactions in water Xiong, Linfeng; Zhang, Hui; He, Zidong New Journal of Chemistry, Vol. 42, Issue 2 https://doi.org/10.1039/C7NJ04209D	journal	January 2018
Chemoenzymatic one-pot reaction of noncompatible catalysts: combining enzymatic ester hydrolysis with Cu( i )/bipyridine catalyzed oxidation in aqueous medium Sand, Henning; Weberskirch, Ralf RSC Advances, Vol. 7, Issue 53 https://doi.org/10.1039/C7RA05451C	journal	January 2017
Chiral salen manganese complex encapsulated within zeolite Y: a heterogeneous enantioselective catalyst for the epoxidation of alkenes Sabater, María J.; Corma, Avelino; Domenech, Antonio Chemical Communications, Issue 14 https://doi.org/10.1039/a701337j	journal	January 1997
Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis Nicolaou, K. C.; Montagnon, Tamsyn; Snyder, Scott A. Chemical Communications, Issue 5 https://doi.org/10.1039/b209440c	journal	January 2003
One-pot multi-step synthesis: a challenge spawning innovation Broadwater, Steven J.; Roth, Shoshannah L.; Price, Kristin E. Organic & Biomolecular Chemistry, Vol. 3, Issue 16 https://doi.org/10.1039/b506621m	journal	January 2005
Carrier enabled catalytic reaction cascades Veum, Lars; Hanefeld, Ulf Chemical Communications, Issue 8 https://doi.org/10.1039/b512366f	journal	January 2006
Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility O'Reilly, Rachel K.; Hawker, Craig J.; Wooley, Karen L. Chemical Society Reviews, Vol. 35, Issue 11 https://doi.org/10.1039/b514858h	journal	January 2006
Metal–organic framework materials as catalysts Lee, JeongYong; Farha, Omar K.; Roberts, John Chemical Society Reviews, Vol. 38, Issue 5, p. 1450-1459 https://doi.org/10.1039/b807080f	journal	January 2009
Molecular recognition driven catalysis using polymeric nanoreactors Cotanda, Pepa; O'Reilly, Rachel K. Chemical Communications, Vol. 48, Issue 83 https://doi.org/10.1039/c2cc35655d	journal	January 2012
A Highly Stereoselective Preparation of l -Isopulegol Nakatani, Yôichi; Kawashima, Kaoru Synthesis, Vol. 1978, Issue 02 https://doi.org/10.1055/s-1978-24696	journal	January 1978
Domino Reactions in Organic Synthesis Breinbauer, Rolf Synthesis, Vol. 2007, Issue 5 https://doi.org/10.1055/s-2007-972004	journal	March 2007
Living Radical Polymerization by the RAFT Process – A Third Update Moad, Graeme; Rizzardo, Ezio; Thang, San H. Australian Journal of Chemistry, Vol. 65, Issue 8 https://doi.org/10.1071/CH12295	journal	January 2012
Nitroxide-Mediated Radical Polymerization: Limitations and Versatility Grubbs, Robert B. Polymer Reviews, Vol. 51, Issue 2 https://doi.org/10.1080/15583724.2011.566405	journal	April 2011
Multicompartment Micelles from ABC Miktoarm Stars in Water Li, Z. Science, Vol. 306, Issue 5693 https://doi.org/10.1126/science.1103350	journal	October 2004
Protein Structures Forming the Shell of Primitive Bacterial Organelles Kerfeld, C. A. Science, Vol. 309, Issue 5736 https://doi.org/10.1126/science.1113397	journal	August 2005
Living Polymerization Methods Webster, O. W. Science, Vol. 251, Issue 4996 https://doi.org/10.1126/science.251.4996.887	journal	February 1991
Bacterial Microcompartments Bobik, Thomas A. Microbe Magazine, Vol. 2, Issue 1 https://doi.org/10.1128/microbe.2.25.1	journal	January 2007
Bacterial Microcompartments Kerfeld, Cheryl A.; Heinhorst, Sabine; Cannon, Gordon C. Annual Review of Microbiology, Vol. 64, Issue 1 https://doi.org/10.1146/annurev.micro.112408.134211	journal	October 2010
Catalytic polymeric nanoreactors: more than a solid supported catalyst Cotanda, Pepa; Petzetakis, Nikos; O'Reilly, Rachel K. MRS Communications, Vol. 2, Issue 4 https://doi.org/10.1557/mrc.2012.26	journal	October 2012

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