Electrically sensing Hachimoji DNA nucleotides through a hybrid graphene/ h -BN nanopore

de Souza, Fábio A. L.; Sivaraman, Ganesh; Fyta, Maria; Scheicher, Ralph H.; Scopel, Wanderlã L.; Amorim, Rodrigo G.

doi:10.1039/D0NR04363J

Title: Electrically sensing Hachimoji DNA nucleotides through a hybrid graphene/ h -BN nanopore

Journal Article · 31 December 2019 · Nanoscale

DOI: https://doi.org/10.1039/D0NR04363J · OSTI ID:1651235

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Federal Institute of Education, Science and Technology of Espírito Santo, Ibatiba/ES, Brazil
Argonne Leadership Computing Facility, Argonne National Laboratory, Lemont, USA, Data Science and Learning Division
Institute for Computational Physics, Universität Stuttgart, Stuttgart, Germany
Division of Materials Theory, Department of Physics and Astronomy, Uppsala University, Sweden
Departamento de Física, Universidade Federal do Espírito Santo-UFES, Vitória/ES, Brazil
Departamento de Física, ICEx, Universidade Federal Fluminense – UFF, Volta Redonda/RJ, Brazil

We show that synthetic Hachimoji nucleobases can be reliably sensed by analysing the strength and duration of characteristic electrical signals generated when their presence in a nanopore modulates the conductance of an adjacent carbon wire.

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Sponsoring Organization:: USDOE Office of Science (SC); Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq); Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1651235

Journal Information:: Nanoscale, Journal Name: Nanoscale; ISSN NANOHL; ISSN 2040-3364

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United Kingdom

Language:: English

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