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Title: Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.)

Abstract

More than a billion people worldwide may be selenium (Se) deficient, and supplementation with Se-rich Brazil nuts may be a good strategy to prevent deficiency. Since different forms of Se have different nutritional value, and Se is toxic at elevated levels, careful seed characterization is important. Variation in Se concentration and correlations of this element with other nutrients were found in two batches of commercially available nuts. Selenium tissue localization and specification were further determined. Mean Se levels were between 28 and 49 mg kg-1, with up to 8-fold seed-to-seed variation (n = 13) within batches. Brazil nut Se was mainly in organic form. While present throughout the seed, Se was most concentrated in a ring 1 to 2 mm below the surface. While healthy, Brazil nuts should be consumed in moderation. Consumption of one seed (5 g) from a high-Se area meets its recommended daily allowance; the recommended serving size of 30 g may exceed the allowable daily intake (400 μg) or even its toxicity threshold (1200 μg). Based on these findings, the recommended serving size may be re-evaluated, consumers should be warned not to exceed the serving size and the seed may be sold as part of mixedmore » nuts, to avoid excess Se intake.« less

Authors:
ORCiD logo [1];  [1];  [2];  [1];  [3]; ORCiD logo [1]
  1. Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
  2. National Laboratory for Genetic Resources Preservation, USDA-ARS, Fort Collins, CO 80521, USA
  3. Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Science Foundation (NSF)
OSTI Identifier:
1628521
Grant/Contract Number:  
AC02-05CH11231; IOS-1456361
Resource Type:
Accepted Manuscript
Journal Name:
Plants
Additional Journal Information:
Journal Volume: 8; Journal Issue: 8; Journal ID: ISSN 2223-7747
Publisher:
MDPI
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; Plant Sciences

Citation Formats

Lima, Leonardo W., Stonehouse, Gavin C., Walters, Christina, Mehdawi, Ali F. El, Fakra, Sirine C., and Pilon-Smits, Elizabeth A. H.. Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.). United States: N. p., 2019. Web. https://doi.org/10.3390/plants8080289.
Lima, Leonardo W., Stonehouse, Gavin C., Walters, Christina, Mehdawi, Ali F. El, Fakra, Sirine C., & Pilon-Smits, Elizabeth A. H.. Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.). United States. https://doi.org/10.3390/plants8080289
Lima, Leonardo W., Stonehouse, Gavin C., Walters, Christina, Mehdawi, Ali F. El, Fakra, Sirine C., and Pilon-Smits, Elizabeth A. H.. Thu . "Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.)". United States. https://doi.org/10.3390/plants8080289. https://www.osti.gov/servlets/purl/1628521.
@article{osti_1628521,
title = {Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.)},
author = {Lima, Leonardo W. and Stonehouse, Gavin C. and Walters, Christina and Mehdawi, Ali F. El and Fakra, Sirine C. and Pilon-Smits, Elizabeth A. H.},
abstractNote = {More than a billion people worldwide may be selenium (Se) deficient, and supplementation with Se-rich Brazil nuts may be a good strategy to prevent deficiency. Since different forms of Se have different nutritional value, and Se is toxic at elevated levels, careful seed characterization is important. Variation in Se concentration and correlations of this element with other nutrients were found in two batches of commercially available nuts. Selenium tissue localization and specification were further determined. Mean Se levels were between 28 and 49 mg kg-1, with up to 8-fold seed-to-seed variation (n = 13) within batches. Brazil nut Se was mainly in organic form. While present throughout the seed, Se was most concentrated in a ring 1 to 2 mm below the surface. While healthy, Brazil nuts should be consumed in moderation. Consumption of one seed (5 g) from a high-Se area meets its recommended daily allowance; the recommended serving size of 30 g may exceed the allowable daily intake (400 μg) or even its toxicity threshold (1200 μg). Based on these findings, the recommended serving size may be re-evaluated, consumers should be warned not to exceed the serving size and the seed may be sold as part of mixed nuts, to avoid excess Se intake.},
doi = {10.3390/plants8080289},
journal = {Plants},
number = 8,
volume = 8,
place = {United States},
year = {2019},
month = {8}
}

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Works referenced in this record:

The importance of selenium to human health
journal, July 2000


An Overview of Selenium Uptake, Metabolism, and Toxicity in Plants
journal, January 2017


Revised reference values for selenium intake
journal, October 2015

  • Kipp, A. P.; Strohm, D.; Brigelius-Flohé, R.
  • Journal of Trace Elements in Medicine and Biology, Vol. 32
  • DOI: 10.1016/j.jtemb.2015.07.005

Intake of Selenium in the Prevention of Prostate Cancer: a Systematic Review and Meta-analysis*
journal, November 2005

  • Etminan, Mahyar; FitzGerald, J. Mark; Gleave, Martin
  • Cancer Causes & Control, Vol. 16, Issue 9
  • DOI: 10.1007/s10552-005-0334-2

Seasonal fluctuations of selenium and sulfur accumulation in selenium hyperaccumulators and related nonaccumulators
journal, November 2006


Selenium, Selenoproteins, and Female Reproduction: A Review
journal, November 2018


Environmental Selenium Research: From Microscopic Processes to Global Understanding
journal, December 2011

  • Winkel, Lenny H. E.; Johnson, C. Annette; Lenz, Markus
  • Environmental Science & Technology, Vol. 46, Issue 2
  • DOI: 10.1021/es203434d

EURRECA—Estimating Selenium Requirements for Deriving Dietary Reference Values
journal, January 2013

  • Hurst, Rachel; Collings, Rachel; Harvey, Linda J.
  • Critical Reviews in Food Science and Nutrition, Vol. 53, Issue 10
  • DOI: 10.1080/10408398.2012.742861

Selenium and Type 2 Diabetes: Systematic Review
journal, December 2018

  • Kohler, Lindsay; Foote, Janet; Kelley, Connor
  • Nutrients, Vol. 10, Issue 12
  • DOI: 10.3390/nu10121924

Epidemiology of selenium and type 2 diabetes: Can we make sense of it?
journal, December 2013


Selenium and Bladder Cancer Risk: a Meta-analysis
journal, August 2010

  • Amaral, A. F. S.; Cantor, K. P.; Silverman, D. T.
  • Cancer Epidemiology Biomarkers & Prevention, Vol. 19, Issue 9
  • DOI: 10.1158/1055-9965.EPI-10-0544

Selenomethionine: A Review of Its Nutritional Significance, Metabolism and Toxicity
journal, July 2000


The relationship of selenium tolerance and speciation in Lecythidaceae species
journal, January 2013

  • Németh, Anikó; García Reyes, Juan Francisco; Kosáry, Judit
  • Metallomics, Vol. 5, Issue 12
  • DOI: 10.1039/c3mt00140g

The Properties, Functions, and Use of Selenium Compounds in Living Organisms
journal, July 2012

  • Bodnar, Malgorzata; Konieczka, Piotr; Namiesnik, Jacek
  • Journal of Environmental Science and Health, Part C, Vol. 30, Issue 3
  • DOI: 10.1080/10590501.2012.705164

Plasma Selenium Levels and Risk of Hepatocellular Carcinoma among Men with Chronic Hepatitis Virus Infection
journal, August 1999


Evolutionary aspects of elemental hyperaccumulation
journal, October 2013


Selenium and human health
journal, March 2012


The epidemiology of selenium deficiency in the etiological study of endemic diseases in China
journal, February 1993


Selenium in the Environment, Metabolism and Involvement in Body Functions
journal, March 2013


Observations on the Fruits and Seeds of Neotropical Lecythidaceae
journal, January 1978

  • Prance, Ghillean T.; Mori, Scott A.
  • Brittonia, Vol. 30, Issue 1
  • DOI: 10.2307/2806452

Brazil nuts: Nutritional composition, health benefits and safety aspects
journal, October 2017


Nitric acid digestion and multi‐element analysis of plant material by inductively coupled plasma spectrometry
journal, January 1987

  • Zarcinas, B. A.; Cartwright, B.; Spouncer, L. R.
  • Communications in Soil Science and Plant Analysis, Vol. 18, Issue 1
  • DOI: 10.1080/00103628709367806

Soil and foliar application of selenium in rice biofortification
journal, September 2013

  • Boldrin, Paulo Fernandes; Faquin, Valdemar; Ramos, Sílvio Júnio
  • Journal of Food Composition and Analysis, Vol. 31, Issue 2
  • DOI: 10.1016/j.jfca.2013.06.002

Selenium-Enriched Breads and Their Benefits in Human Nutrition and Health as Affected by Agronomic, Milling, and Baking Factors
journal, March 2015

  • Lazo-Vélez, Marco A.; Chávez-Santoscoy, Alejandra; Serna-Saldivar, Sergio O.
  • Cereal Chemistry Journal, Vol. 92, Issue 2
  • DOI: 10.1094/CCHEM-05-14-0110-RW

Microbial-enhanced Selenium and Iron Biofortification of Wheat ( Triticum aestivum L.) - Applications in Phytoremediation and Biofortification
journal, November 2014

  • Yasin, Muhammad; El-Mehdawi, Ali Farag; Anwar, Aneela
  • International Journal of Phytoremediation, Vol. 17, Issue 4
  • DOI: 10.1080/15226514.2014.922920

Correlative Cryogenic Spectromicroscopy to Investigate Selenium Bioreduction Products
journal, December 2017

  • Fakra, Sirine C.; Luef, Birgit; Castelle, Cindy J.
  • Environmental Science & Technology, Vol. 52, Issue 2
  • DOI: 10.1021/acs.est.5b01409

The roles of selenium in protecting plants against abiotic stresses
journal, March 2013


Selenium accumulation in flowers and its effects on pollination
journal, July 2011


Variations in the accumulation, localization and rate of metabolization of selenium in mature Zea mays plants supplied with selenite or selenate
journal, September 2015


Selenium, zinc, and thyroid hormones in healthy subjects: Low T3/T4 ratio in the elderly is related to impaired selenium status
journal, January 1996

  • Olivieri, Oliviero; Girelli, Domenico; Stanzial, Anna Maria
  • Biological Trace Element Research, Vol. 51, Issue 1
  • DOI: 10.1007/BF02790145

Mechanisms of selenium hyperaccumulation in plants: A survey of molecular, biochemical and ecological cues
journal, November 2018

  • Lima, Leonardo Warzea; Pilon-Smits, Elizabeth A. H.; Schiavon, Michela
  • Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1862, Issue 11
  • DOI: 10.1016/j.bbagen.2018.03.028

Selenium Biofortification and Phytoremediation Phytotechnologies: A Review
journal, January 2017

  • Schiavon, Michela; Pilon-Smits, Elizabeth A. H.
  • Journal of Environment Quality, Vol. 46, Issue 1
  • DOI: 10.2134/jeq2016.09.0342

Consumption of Brazil nuts with high selenium levels increased inflammation biomarkers in obese women: A randomized controlled trial
journal, July 2019

  • Duarte, Graziela Biude Silva; Reis, Bruna Zavarize; Rogero, Marcelo Macedo
  • Nutrition, Vol. 63-64
  • DOI: 10.1016/j.nut.2019.02.009

Ecological aspects of plant selenium hyperaccumulation: Ecology of selenium hyperaccumulation
journal, December 2011


Natural variation of selenium in Brazil nuts and soils from the Amazon region
journal, December 2017


Toxicology of Micronutrients: Adverse Effects and Uncertainty
journal, February 2006


Characterization of Selenium Species in Brazil Nuts by HPLC−ICP-MS and ES-MS
journal, September 2002

  • Vonderheide, Anne P.; Wrobel, Kazimierz; Kannamkumarath, Sasi S.
  • Journal of Agricultural and Food Chemistry, Vol. 50, Issue 20
  • DOI: 10.1021/jf0256541

Selenium in global food systems
journal, May 2001


Variation in the Selenium Content of Individual Brazil nuts
journal, January 1989


    Works referencing / citing this record:

    Benefits of the consumption of Brazil nut (Bertholletia excelsa) extract in male reproductive parameters of streptozotocin-induced diabetic rats
    journal, February 2020

    • Nascimento, Leonardo Parreira Silva; Pires, Vanessa Cardoso; Ribeiro, Daniel Araki
    • Journal of Diabetes & Metabolic Disorders, Vol. 19, Issue 1
    • DOI: 10.1007/s40200-020-00490-8