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Title: The Establishment of the Household Air Pollution Consortium (HAPCO)

Journal Article · · Atmosphere (Basel)
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  1. Albert Einstein College of Medicine, Bronx, NY (United States). Dept. of Epidemiology and Population Health
  2. Aichi Cancer Center Research Inst., Nagoya (Japan). Division of Epidemiology and Prevention
  3. National Inst. of Environmental Health Science, Research Triangle Park, NC (United States). Epidemiology Branch
  4. Radiation Effects Research Foundation, Hiroshima (Japan). Dept. of Epidemiology
  5. Vanderbilt Univ., Nashville, TN (United States). School of Medicine. Vanderbilt Inst. for Global Health
  6. National Inst. of Public Health, Cuernavaca, Morelos (Mexico)
  7. Seoul National Univ. (Korea, Republic of). Dept. of Preventative Medicine
  8. Tohoku Univ., Miyagi (Japan). Graduate School of Medicine. Dept. of Health Informatics and Public Health. Division of Epidemiology
  9. Tehran Univ. of Medical Sciences, Tehran (Iran). Digestive Diseases Research Inst.
  10. Centre de Recherche du CHU Sainte-Justine, Montreal, Quebec (Canada). CARTaGENE
  11. BC Cancer, Vancouver, BC (Canada)
  12. Vanderbilt Univ., Nashville, TN (United States). School of Medicine. Center for Health Scervices
  13. National Cancer Center, Tokyo, (Japan). Center for Cancer Control and Information Services. Division of Cancer Statistics and Integration
  14. Univ. of Tokyo (Japan). Graduate School of Medicine. Dept. of Global Health Policy
  15. National Cancer Institute, Bethesda, MD (United States). Division of Cancer Epidemiology and Genetics. Occupational and Environmental Epidemiology Branch
  16. Utrecht Univ. (Netherlands). Inst. for Risk Assessment Services
  17. National Cancer Center, Tokyo (Japan). Center for Public Health Sciences. Epidemiology and Prevention Group
  18. Univ. of British Columbia, Vancouver, BC (Canada). School of Population and Public Health
  19. National Inst. of Public Health, Cuernavaca, Morelos (Mexico); Harvard T.H. Chan School of Public Health, Boston, MA (United States). Dept. of Global Health and Population
  20. Seoul National Univ. (Korea, Republic of). College of Medicine. Dept. of Preventative Medicine
  21. Aichi Cancer Center Research Inst., Nagoya (Japan)
  22. Univ. of Chicago, IL (United States). Dept. of Health Sciences
  23. Vanderbilt Univ., Nashville, TN (United States). School of Medicine. Center for Health Sciences
  24. Icahn School of Medicine at Mount Sinai, New York, NY (United States). The Tisch Cancer Inst; Univ. of Bologna (Italy). Dept. of Medical and Surgical Sciences
+ Show Author Affiliations

Household air pollution (HAP) is of public health concern, with ~3 billion people worldwide (including >15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet the epidemiological evidence on carcinogenicity of HAP from biomass use, primarily wood, is not conclusive. To robustly assess biomass’s carcinogenic potential, prospective studies of individuals experiencing a variety of HAP exposures are needed. We have built a global consortium of 13 prospective cohorts (HAPCO: Household Air Pollution Consortium) that have site- and disease-specific mortality and solid fuel use data, for a combined sample size of 587,257 participants and 57,483 deaths. HAPCO provides a novel opportunity to assess the association of HAP with lung cancer death while controlling for important confounders such as tobacco and outdoor air pollution exposures. HAPCO is also uniquely positioned to determine the risks associated with cancers other than lung as well as nonmalignant respiratory and cardiometabolic outcomes, for which prospective epidemiologic research is limited. HAPCO will facilitate research to address public health concerns associated with HAP-attributed exposures by enabling investigators to evaluate sex-specific and smoking status-specific effects under various exposure scenarios.

Research Organization:
Albert Einstein College of Medicine, Bronx, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division
Grant/Contract Number:
FG02-00ER41132
OSTI ID:
1628309
Journal Information:
Atmosphere (Basel), Vol. 10, Issue 7; ISSN 2073-4433
Publisher:
MDPICopyright Statement
Country of Publication:
United States
Language:
English

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Spatiotemporal air pollution exposure assessment for a Canadian population-based lung cancer case-control study journal April 2012
Cohort Profile: The Golestan Cohort Study--a prospective study of oesophageal cancer in northern Iran journal March 2009
Spatiotemporal air pollution exposure assessment for a Canadian population-based lung cancer case-control study text January 2012
Millions Dead: How Do We Know and What Does It Mean? Methods Used in the Comparative Risk Assessment of Household Air Pollution journal March 2014
Variation in lung cancer risk by smoky coal subtype in Xuanwei, China journal November 2008
The epidemic status and risk factors of lung cancer in Xuanwei City, Yunnan Province, China journal December 2012
Carcinogenicity of household solid fuel combustion and of high-temperature frying journal December 2006
Global Land Use Regression Model for Nitrogen Dioxide Air Pollution journal June 2017
Portable stove use is associated with lower lung cancer mortality risk in lifetime smoky coal users journal November 2008
Chronic Obstructive Pulmonary Disease Secondary to Household Air Pollution journal May 2015
Coronary heart disease and household air pollution from use of solid fuel: a systematic review journal May 2016
Cohort Profile: The Golestan Cohort Study--a prospective study of oesophageal cancer in northern Iran journal March 2009
Household coal use and lung cancer: systematic review and meta-analysis of case-control studies, with an emphasis on geographic variation journal January 2011
Cohort profile of the CARTaGENE study: Quebec’s population-based biobank for public health and personalized genomics journal October 2012
Cohort Profile: The Shanghai Men’s Health Study journal March 2015
Cohort Profile: The Mexican Teachers’ Cohort (MTC) journal September 2015
Cohort Profile: The British Columbia Generations Project (BCGP) journal August 2018
Lung cancer death rates by smoking status: Comparison of the Three-Prefecture Cohort study in Japan to the Cancer Prevention Study II in the USA journal February 2005
Millions Dead: How Do We Know and What Does It Mean? Methods Used in the Comparative Risk Assessment of Household Air Pollution journal March 2014
In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium journal December 2010
Research Opportunities for Cancer Associated with Indoor Air Pollution from Solid-Fuel Combustion journal November 2012
Estimating the Number of Low-Income Americans Exposed to Household Air Pollution from Burning Solid Fuels journal August 2014
Long-Term Air Pollution Exposure and Blood Pressure in the Sister Study journal October 2015
The Sister Study Cohort: Baseline Methods and Participant Characteristics
  • Sandler, Dale P.; Hodgson, M. Elizabeth; Deming-Halverson, Sandra L.
  • Environmental Health Perspectives, Vol. 125, Issue 12 https://doi.org/10.1289/ehp1923
journal December 2017
Comments on “Studies of the Mortality of Atomic Bomb Survivors, Report 14, 1950–2003: An Overview of Cancer and Noncancer Diseases” (Radiat Res 2012; 177:229–43) journal September 2012
Is Household Air Pollution a Risk Factor for Eye Disease? journal October 2013

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