Carrying out an optimal experiment

Dauter, Zbigniew

doi:10.1107/s0907444909038578

Title: Carrying out an optimal experiment

Journal Article · 23 March 2010 · Acta Crystallographica. Section D: Biological Crystallography

DOI: https://doi.org/10.1107/s0907444909038578 · OSTI ID:1625664

Dauter, Zbigniew ^[1]

Argonne National Lab. (ANL), Argonne, IL (United States). National Cancer Inst. MCL. Synchrotron Radiation Research Section; DOE/OSTI

Diffraction data collection is the last experimental stage in structural crystallography. It has several technical and theoretical aspects and a compromise usually has to be found between various parameters in order to achieve optimal data quality. The influence and importance of various experimental parameters and their consequences are discussed in the context of different data applications, such as molecular replacement, anomalous phasing, high-resolution refinement or searching for ligands.

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences & Biosciences Division

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1625664

Journal Information:: Acta Crystallographica. Section D: Biological Crystallography, Journal Name: Acta Crystallographica. Section D: Biological Crystallography Journal Issue: 4 Vol. 66; ISSN 0907-4449

Publisher:: International Union of CrystallographyCopyright Statement

Country of Publication:: United States

Language:: English

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SAD phasing using iodide ions in a high-throughput structural genomics environment Abendroth, Jan; Gardberg, Anna S.; Robinson, John I. Journal of Structural and Functional Genomics, Vol. 12, Issue 2 https://doi.org/10.1007/s10969-011-9101-7	journal	February 2011
Advanced Crystallographic Data Collection Protocols for Experimental Phasing Finke, Aaron D.; Panepucci, Ezequiel; Vonrhein, Clemens Nucleic Acid Crystallography, 175–191 https://doi.org/10.1007/978-1-4939-2763-0_11	book	January 2016
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PRIGo: a new multi-axis goniometer for macromolecular crystallography Waltersperger, Sandro; Olieric, Vincent; Pradervand, Claude Journal of Synchrotron Radiation, Vol. 22, Issue 4 https://doi.org/10.1107/s1600577515005354	journal	May 2015
Where is crystallography going? Grimes, Jonathan M.; Hall, David R.; Ashton, Alun W. Acta Crystallographica Section D Structural Biology, Vol. 74, Issue 2 https://doi.org/10.1107/s2059798317016709	journal	February 2018

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