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Title: Deciphering nanoconfinement effects on molecular orientation and reaction intermediate by single molecule imaging

Abstract

Nanoconfinement could dramatically change molecular transport and reaction kinetics in heterogeneous catalysis. Here we specifically design a core-shell nanocatalyst with aligned linear nanopores for single-molecule studies of the nanoconfinement effects. The quantitative single-molecule measurements reveal unusual lower adsorption strength and higher catalytic activity on the confined metal reaction centres within the nanoporous structure. More surprisingly, the nanoconfinement effects on enhanced catalytic activity are larger for catalysts with longer and narrower nanopores. Experimental evidences, including molecular orientation, activation energy, and intermediate reactive species, have been gathered to provide a molecular level explanation on how the nanoconfinement effects enhance the catalyst activity, which is essential for the rational design of highly-efficient catalysts.

Authors:
 [1]; ORCiD logo [2];  [3];  [4];  [5]; ORCiD logo [2];  [3]
  1. Georgia State Univ., Atlanta, GA (United States). Dept. of Chemistry
  2. Iowa State Univ., Ames, IA (United States) and Ames Lab., Ames, IA (United States). Dept. of Chemistry
  3. Georgia State Univ., Atlanta, GA (United States). Dept. of Chemistry
  4. Soochow University, Suzhou (China). Center for Soft Condensed Matter Physics and Interdisciplinary Research & School of Physical Science and Technology
  5. Soochow University, Suzhou (China). Center for Soft Condensed Matter Physics and Interdisciplinary Research & School of Physical Science and Technology
Publication Date:
Research Org.:
Ames Laboratory (AMES), Ames, IA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1624206
Grant/Contract Number:  
AC02-07CH11358
Resource Type:
Accepted Manuscript
Journal Name:
Nature Communications
Additional Journal Information:
Journal Volume: 10; Journal Issue: 1; Journal ID: ISSN 2041-1723
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English
Subject:
Science & Technology - Other Topics

Citation Formats

Dong, Bin, Pei, Yuchen, Mansour, Nourhan, Lu, Xuemei, Yang, Kai, Huang, Wenyu, and Fang, Ning. Deciphering nanoconfinement effects on molecular orientation and reaction intermediate by single molecule imaging. United States: N. p., 2019. Web. doi:10.1038/s41467-019-12799-x.
Dong, Bin, Pei, Yuchen, Mansour, Nourhan, Lu, Xuemei, Yang, Kai, Huang, Wenyu, & Fang, Ning. Deciphering nanoconfinement effects on molecular orientation and reaction intermediate by single molecule imaging. United States. https://doi.org/10.1038/s41467-019-12799-x
Dong, Bin, Pei, Yuchen, Mansour, Nourhan, Lu, Xuemei, Yang, Kai, Huang, Wenyu, and Fang, Ning. Wed . "Deciphering nanoconfinement effects on molecular orientation and reaction intermediate by single molecule imaging". United States. https://doi.org/10.1038/s41467-019-12799-x. https://www.osti.gov/servlets/purl/1624206.
@article{osti_1624206,
title = {Deciphering nanoconfinement effects on molecular orientation and reaction intermediate by single molecule imaging},
author = {Dong, Bin and Pei, Yuchen and Mansour, Nourhan and Lu, Xuemei and Yang, Kai and Huang, Wenyu and Fang, Ning},
abstractNote = {Nanoconfinement could dramatically change molecular transport and reaction kinetics in heterogeneous catalysis. Here we specifically design a core-shell nanocatalyst with aligned linear nanopores for single-molecule studies of the nanoconfinement effects. The quantitative single-molecule measurements reveal unusual lower adsorption strength and higher catalytic activity on the confined metal reaction centres within the nanoporous structure. More surprisingly, the nanoconfinement effects on enhanced catalytic activity are larger for catalysts with longer and narrower nanopores. Experimental evidences, including molecular orientation, activation energy, and intermediate reactive species, have been gathered to provide a molecular level explanation on how the nanoconfinement effects enhance the catalyst activity, which is essential for the rational design of highly-efficient catalysts.},
doi = {10.1038/s41467-019-12799-x},
journal = {Nature Communications},
number = 1,
volume = 10,
place = {United States},
year = {2019},
month = {10}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record

Figures / Tables:

Fig. 1 Fig. 1: Reaction kinetics in confining materials with variable nanopore morphologies. a Schematic of single-particle single-molecule imaging setup (left) and chemical conversion processes inside nanopore (right). b Reaction kinetics for different nanopore lengths and diameters at single particle single molecule level. Adsorption/desorption equilibrium constant KAR c and rate constant keffmore » d are obtained from fitting the single particle single molecule kinetics data with the DLH model. e Ensemble results of reaction rates of nanocatalysts with variable porous shell thickness and pore diameter are shown at same amount of particle concentrations (~1012 particles mL−1). It should be noted that the shallow excitation depth of TIRFM (<250 nm) makes it challenging to compare single particle catalytic activities of thicker shells (>150 nm) to those with thin shells (40–120 nm) quantitatively. The error bars are calculated uncertainties from fitting catalytic reaction kinetic data over 40 single nanocatalysts for each nanopore morphology (b and c) and calculated standard deviation (s.d.) from three trials of ensemble measurements (e), respectively« less

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Works referenced in this record:

Toward Fundamentals of Confined Catalysis in Carbon Nanotubes
journal, December 2014

  • Xiao, Jianping; Pan, Xiulian; Guo, Shujing
  • Journal of the American Chemical Society, Vol. 137, Issue 1
  • DOI: 10.1021/ja511498s

Study of Confinement and Catalysis Effects of the Reaction of Methylation of Benzene by Methanol in H-Beta and H-ZSM-5 Zeolites by Topological Analysis of Electron Density
journal, February 2018

  • Zalazar, María Fernanda; Paredes, Esteban Nadal; Romero Ojeda, Gonzalo D.
  • The Journal of Physical Chemistry C, Vol. 122, Issue 6
  • DOI: 10.1021/acs.jpcc.7b10297

A Link between Reactivity and Local Structure in Acid Catalysis on Zeolites
journal, April 2008

  • Bhan, Aditya; Iglesia, Enrique
  • Accounts of Chemical Research, Vol. 41, Issue 4
  • DOI: 10.1021/ar700181t

The catalytic diversity of zeolites: confinement and solvation effects within voids of molecular dimensions
journal, January 2013

  • Gounder, Rajamani; Iglesia, Enrique
  • Chemical Communications, Vol. 49, Issue 34
  • DOI: 10.1039/c3cc40731d

Lab-in-a-Shell: Encapsulating Metal Clusters for Size Sieving Catalysis
journal, August 2014

  • Qiao, Zhen-An; Zhang, Pengfei; Chai, Song-Hai
  • Journal of the American Chemical Society, Vol. 136, Issue 32
  • DOI: 10.1021/ja505903r

Silica-supported ultra small gold nanoparticles as nanoreactors for the etherification of silanes
journal, January 2016

  • Wang, Cui; Lin, Xijie; Ge, Yuzhen
  • RSC Advances, Vol. 6, Issue 104
  • DOI: 10.1039/C6RA22359A

Pt-supported Spherical Mesoporous Silica as a Nanosized Catalyst for Efficient Liquid-Phase Hydrogenation
journal, February 2014


Transport mechanisms in nanopores and nanochannels: can we mimic nature?
journal, April 2015


The complexity of mesoporous silica nanomaterials unravelled by single molecule microscopy
journal, January 2011

  • Lebold, Timo; Michaelis, Jens; Bräuchle, Christoph
  • Physical Chemistry Chemical Physics, Vol. 13, Issue 11
  • DOI: 10.1039/c0cp02210a

How Does Confinement Change Ligand–Receptor Binding Equilibrium? Protein Binding in Nanopores and Nanochannels
journal, September 2015

  • Tagliazucchi, Mario; Szleifer, Igal
  • Journal of the American Chemical Society, Vol. 137, Issue 39
  • DOI: 10.1021/jacs.5b05032

Fluorescence Imaging of Single-Molecule Retention Trajectories in Reversed-Phase Chromatographic Particles
journal, September 2013

  • Cooper, Justin T.; Peterson, Eric M.; Harris, Joel M.
  • Analytical Chemistry, Vol. 85, Issue 19
  • DOI: 10.1021/ac402251r

Chemical reaction equilibrium in nanoporous materials: NO dimerization reaction in carbon slit nanopores
journal, February 2006

  • Lísal, Martin; Brennan, John K.; Smith, William R.
  • The Journal of Chemical Physics, Vol. 124, Issue 6
  • DOI: 10.1063/1.2171213

Combining reactive and configurational-bias Monte Carlo: Confinement influence on the propene metathesis reaction system in various zeolites
journal, December 2006

  • Jakobtorweihen, S.; Hansen, N.; Keil, F. J.
  • The Journal of Chemical Physics, Vol. 125, Issue 22
  • DOI: 10.1063/1.2404658

Density functional study of chemical reaction equilibrium for dimerization reactions in slit and cylindrical nanopores
journal, April 2009

  • Malijevský, Alexandr; Lísal, Martin
  • The Journal of Chemical Physics, Vol. 130, Issue 16
  • DOI: 10.1063/1.3125925

Reactive Monte Carlo and grand-canonical Monte Carlo simulations of the propene metathesis reaction system
journal, April 2005

  • Hansen, Niels; Jakobtorweihen, Sven; Keil, Frerich J.
  • The Journal of Chemical Physics, Vol. 122, Issue 16
  • DOI: 10.1063/1.1884108

Understanding nano effects in catalysis
journal, May 2015

  • Yang, Fan; Deng, Dehui; Pan, Xiulian
  • National Science Review, Vol. 2, Issue 2
  • DOI: 10.1093/nsr/nwv024

Kinetics of Proteolytic Reactions in Nanoporous Materials
journal, October 2009

  • Bi, Hongyan; Qiao, Liang; Busnel, Jean-Marc
  • Journal of Proteome Research, Vol. 8, Issue 10
  • DOI: 10.1021/pr9003954

Giant Raman Response to the Encapsulation of Sulfur in Narrow Diameter Single-Walled Carbon Nanotubes
journal, December 2015

  • Li, Guanghui; Fu, Chengyin; Oviedo, M. Belén
  • Journal of the American Chemical Society, Vol. 138, Issue 1
  • DOI: 10.1021/jacs.5b10598

Reversible trapping and reaction acceleration within dynamically self-assembling nanoflasks
journal, November 2015

  • Zhao, Hui; Sen, Soumyo; Udayabhaskararao, T.
  • Nature Nanotechnology, Vol. 11, Issue 1
  • DOI: 10.1038/nnano.2015.256

Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
journal, August 2006

  • Rust, Michael J.; Bates, Mark; Zhuang, Xiaowei
  • Nature Methods, Vol. 3, Issue 10
  • DOI: 10.1038/nmeth929

Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
journal, September 2006


Spatially resolved observation of crystal-face-dependent catalysis by single turnover counting
journal, February 2006

  • Roeffaers, Maarten B. J.; Sels, Bert F.; Uji-i, Hiroshi
  • Nature, Vol. 439, Issue 7076
  • DOI: 10.1038/nature04502

Quantitative 3D Fluorescence Imaging of Single Catalytic Turnovers Reveals Spatiotemporal Gradients in Reactivity of Zeolite H-ZSM-5 Crystals upon Steaming
journal, April 2015

  • Ristanović, Zoran; Hofmann, Jan P.; De Cremer, Gert
  • Journal of the American Chemical Society, Vol. 137, Issue 20
  • DOI: 10.1021/jacs.5b01698

Single Molecule Nanospectroscopy Visualizes Proton-Transfer Processes within a Zeolite Crystal
journal, October 2016

  • Ristanović, Zoran; Kubarev, Alexey V.; Hofkens, Johan
  • Journal of the American Chemical Society, Vol. 138, Issue 41
  • DOI: 10.1021/jacs.6b06083

Super-Resolution Reactivity Mapping of Nanostructured Catalyst Particles
journal, November 2009

  • Roeffaers, Maarten B.  J.; De Cremer, Gert; Libeert, Julien
  • Angewandte Chemie, Vol. 121, Issue 49
  • DOI: 10.1002/ange.200904944

High-Resolution Single-Molecule Fluorescence Imaging of Zeolite Aggregates within Real-Life Fluid Catalytic Cracking Particles
journal, December 2014

  • Ristanović, Zoran; Kerssens, Marleen M.; Kubarev, Alexey V.
  • Angewandte Chemie International Edition, Vol. 54, Issue 6
  • DOI: 10.1002/anie.201410236

Single-Molecule Fluorescence Microscopy Reveals Local Diffusion Coefficients in the Pore Network of an Individual Catalyst Particle
journal, September 2017

  • Hendriks, Frank C.; Meirer, Florian; Kubarev, Alexey V.
  • Journal of the American Chemical Society, Vol. 139, Issue 39
  • DOI: 10.1021/jacs.7b07139

Quantitative super-resolution imaging uncovers reactivity patterns on single nanocatalysts
journal, February 2012

  • Zhou, Xiaochun; Andoy, Nesha May; Liu, Guokun
  • Nature Nanotechnology, Vol. 7, Issue 4
  • DOI: 10.1038/nnano.2012.18

How Does a Single Pt Nanocatalyst Behave in Two Different Reactions? A Single-Molecule Study
journal, January 2012

  • Han, Kyu Sung; Liu, Guokun; Zhou, Xiaochun
  • Nano Letters, Vol. 12, Issue 3
  • DOI: 10.1021/nl203677b

Single-Molecule Catalysis Mapping Quantifies Site-Specific Activity and Uncovers Radial Activity Gradient on Single 2D Nanocrystals
journal, January 2013

  • Andoy, Nesha May; Zhou, Xiaochun; Choudhary, Eric
  • Journal of the American Chemical Society, Vol. 135, Issue 5
  • DOI: 10.1021/ja309948y

Single-molecule nanocatalysis reveals heterogeneous reaction pathways and catalytic dynamics
journal, November 2008

  • Xu, Weilin; Kong, Jason S.; Yeh, Yun-Ting E.
  • Nature Materials, Vol. 7, Issue 12
  • DOI: 10.1038/nmat2319

Super-Resolution Mapping of Photogenerated Electron and Hole Separation in Single Metal–Semiconductor Nanocatalysts
journal, January 2014

  • Ha, Ji Won; Ruberu, T. Purnima A.; Han, Rui
  • Journal of the American Chemical Society, Vol. 136, Issue 4
  • DOI: 10.1021/ja409011y

Evidence for Crystal-Face-Dependent TiO 2 Photocatalysis from Single-Molecule Imaging and Kinetic Analysis
journal, May 2011

  • Tachikawa, Takashi; Yamashita, Soichiro; Majima, Tetsuro
  • Journal of the American Chemical Society, Vol. 133, Issue 18
  • DOI: 10.1021/ja201415j

Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes
journal, February 2016

  • Sambur, Justin B.; Chen, Tai-Yen; Choudhary, Eric
  • Nature, Vol. 530, Issue 7588
  • DOI: 10.1038/nature16534

Visualizing single-molecule diffusion in mesoporous materials
journal, November 2007

  • Zürner, Andreas; Kirstein, Johanna; Döblinger, Markus
  • Nature, Vol. 450, Issue 7170, p. 705-708
  • DOI: 10.1038/nature06398

Single-Molecule Tracking Studies of Millimeter-Scale Cylindrical Domain Alignment in Polystyrene–Poly(ethylene oxide) Diblock Copolymer Films Induced by Solvent Vapor Penetration
journal, July 2012

  • Tran-Ba, Khanh-Hoa; Finley, Jason J.; Higgins, Daniel A.
  • The Journal of Physical Chemistry Letters, Vol. 3, Issue 15
  • DOI: 10.1021/jz300647z

Direct Visualization of Dye and Oligonucleotide Diffusion in Silica Filaments with Collinear Mesopores
journal, February 2012

  • Feil, Florian; Cauda, Valentina; Bein, Thomas
  • Nano Letters, Vol. 12, Issue 3
  • DOI: 10.1021/nl2039474

Highly Oriented Mesoporous Silica Channels Synthesized in Microgrooves and Visualized with Single-Molecule Diffusion
journal, February 2012

  • Rühle, Bastian; Davies, Melari; Lebold, Timo
  • ACS Nano, Vol. 6, Issue 3
  • DOI: 10.1021/nn2042835

High-Resolution Single-Turnover Mapping Reveals Intraparticle Diffusion Limitation in Ti-MCM-41-Catalyzed Epoxidation
journal, January 2010

  • De Cremer, Gert; Roeffaers, Maarten B. J.; Bartholomeeusen, Evelyne
  • Angewandte Chemie, Vol. 122, Issue 5
  • DOI: 10.1002/ange.200905039

In situ quantitative single-molecule study of dynamic catalytic processes in nanoconfinement
journal, January 2018


Understanding the Optimal Adsorption Energies for Catalyst Screening in Heterogeneous Catalysis
journal, December 2013

  • Yang, Bo; Burch, Robbie; Hardacre, Christopher
  • ACS Catalysis, Vol. 4, Issue 1
  • DOI: 10.1021/cs400727f

Hydrogénations et déshydrogénations par catalyse
journal, July 1911


Adsorption geometry of benzene on Pd(110): Results of first-principles calculations
journal, December 2000


Density-functional study of the adsorption of benzene on the (111), (100) and (110) surfaces of nickel
journal, January 2001


Low-energy electron diffraction and work function studies of adsorbed organic monolayers on the (100) and (111) crystal faces of platinum
journal, February 1976


An Efficient Strategy to Drive Nanoparticles into Carbon Nanotubes and the Remarkable Effect of Confinement on Their Catalytic Performance
journal, March 2009

  • Castillejos, Eva; Debouttière, Pierre-Jean; Roiban, Lucian
  • Angewandte Chemie International Edition, Vol. 48, Issue 14
  • DOI: 10.1002/anie.200805273

Aromatic adsorption on metals via first-principles density functional theory
journal, July 2009

  • Jenkins, S. J.
  • Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 465, Issue 2110
  • DOI: 10.1098/rspa.2009.0119

Chapter 7 Total Internal Reflection Fluorescence Microscopy
book, December 2008


Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization
journal, March 2003

  • Forkey, Joseph N.; Quinlan, Margot E.; Alexander Shaw, M.
  • Nature, Vol. 422, Issue 6930
  • DOI: 10.1038/nature01529

Spectroscopic and Polarization-Dependent Single-Molecule Tracking Reveal the One-Dimensional Diffusion Pathways in Surfactant-Templated Mesoporous Silica
journal, December 2015

  • Kumarasinghe, Ruwandi; Higgins, Eric D.; Ito, Takashi
  • The Journal of Physical Chemistry C, Vol. 120, Issue 1
  • DOI: 10.1021/acs.jpcc.5b10152

Diffusion of Oriented Single Molecules with Switchable Mobility in Networks of Long Unidimensional Nanochannels
journal, February 2008

  • Jung, Christophe; Kirstein, Johanna; Platschek, Barbara
  • Journal of the American Chemical Society, Vol. 130, Issue 5
  • DOI: 10.1021/ja075927e

Diffusional and orientational dynamics of various single terylene diimide conjugates in mesoporous materials
journal, October 2009


Single-Molecule Investigations of Morphology and Mass Transport Dynamics in Nanostructured Materials
journal, July 2015


Molecular Length Dependence of Single Molecule Wobbling within Surfactant- and Solvent-Filled Silica Mesopores
journal, July 2013

  • Pramanik, Rajib; Ito, Takashi; Higgins, Daniel A.
  • The Journal of Physical Chemistry C, Vol. 117, Issue 29
  • DOI: 10.1021/jp404991m

Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies
journal, June 2016


Mechanistic Aspects of Horseradish Peroxidase Elucidated through Single-Molecule Studies
journal, May 2009

  • Gorris, Hans H.; Walt, David R.
  • Journal of the American Chemical Society, Vol. 131, Issue 17
  • DOI: 10.1021/ja9008858

Mechanism and Kinetics of Hydrogen Peroxide Decomposition on Platinum Nanocatalysts
journal, May 2018

  • Serra-Maia, Rui; Bellier, Marion; Chastka, Stephen
  • ACS Applied Materials & Interfaces, Vol. 10, Issue 25
  • DOI: 10.1021/acsami.8b02345

An Efficient Strategy to Drive Nanoparticles into Carbon Nanotubes and the Remarkable Effect of Confinement on Their Catalytic Performance
journal, March 2009

  • Castillejos, Eva; Debouttière, Pierre-Jean; Roiban, Lucian
  • Angewandte Chemie, Vol. 121, Issue 14
  • DOI: 10.1002/ange.200805273

Super-Resolution Reactivity Mapping of Nanostructured Catalyst Particles
journal, November 2009

  • Roeffaers, Maarten B.  J.; De Cremer, Gert; Libeert, Julien
  • Angewandte Chemie International Edition, Vol. 48, Issue 49
  • DOI: 10.1002/anie.200904944

High-Resolution Single-Molecule Fluorescence Imaging of Zeolite Aggregates within Real-Life Fluid Catalytic Cracking Particles
journal, December 2014

  • Ristanović, Zoran; Kerssens, Marleen M.; Kubarev, Alexey V.
  • Angewandte Chemie, Vol. 127, Issue 6
  • DOI: 10.1002/ange.201410236

High-Resolution Single-Turnover Mapping Reveals Intraparticle Diffusion Limitation in Ti-MCM-41-Catalyzed Epoxidation
journal, December 2009

  • De Cremer, Gert; Roeffaers, Maarten B. J.; Bartholomeeusen, Evelyne
  • Angewandte Chemie International Edition, Vol. 49, Issue 5
  • DOI: 10.1002/anie.200905039

An Efficient Strategy to Drive Nanoparticles into Carbon Nanotubes and the Remarkable Effect of Confinement on Their Catalytic Performance
journal, March 2009

  • Castillejos, Eva; Debouttière, Pierre-Jean; Roiban, Lucian
  • Angewandte Chemie, Vol. 121, Issue 14
  • DOI: 10.1002/ange.200805273

Super-Resolution Reactivity Mapping of Nanostructured Catalyst Particles
journal, November 2009

  • Roeffaers, Maarten B.  J.; De Cremer, Gert; Libeert, Julien
  • Angewandte Chemie, Vol. 121, Issue 49
  • DOI: 10.1002/ange.200904944

High-Resolution Single-Turnover Mapping Reveals Intraparticle Diffusion Limitation in Ti-MCM-41-Catalyzed Epoxidation
journal, January 2010

  • De Cremer, Gert; Roeffaers, Maarten B. J.; Bartholomeeusen, Evelyne
  • Angewandte Chemie, Vol. 122, Issue 5
  • DOI: 10.1002/ange.200905039

High-Resolution Single-Molecule Fluorescence Imaging of Zeolite Aggregates within Real-Life Fluid Catalytic Cracking Particles
journal, December 2014

  • Ristanović, Zoran; Kerssens, Marleen M.; Kubarev, Alexey V.
  • Angewandte Chemie International Edition, Vol. 54, Issue 6
  • DOI: 10.1002/anie.201410236

Pt-supported Spherical Mesoporous Silica as a Nanosized Catalyst for Efficient Liquid-Phase Hydrogenation
journal, February 2014


Low-energy electron diffraction and work function studies of adsorbed organic monolayers on the (100) and (111) crystal faces of platinum
journal, February 1976


Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies
journal, June 2016


Fluorescence Imaging of Single-Molecule Retention Trajectories in Reversed-Phase Chromatographic Particles
journal, September 2013

  • Cooper, Justin T.; Peterson, Eric M.; Harris, Joel M.
  • Analytical Chemistry, Vol. 85, Issue 19
  • DOI: 10.1021/ac402251r

Spectroscopic and Polarization-Dependent Single-Molecule Tracking Reveal the One-Dimensional Diffusion Pathways in Surfactant-Templated Mesoporous Silica
journal, December 2015

  • Kumarasinghe, Ruwandi; Higgins, Eric D.; Ito, Takashi
  • The Journal of Physical Chemistry C, Vol. 120, Issue 1
  • DOI: 10.1021/acs.jpcc.5b10152

Study of Confinement and Catalysis Effects of the Reaction of Methylation of Benzene by Methanol in H-Beta and H-ZSM-5 Zeolites by Topological Analysis of Electron Density
journal, February 2018

  • Zalazar, María Fernanda; Paredes, Esteban Nadal; Romero Ojeda, Gonzalo D.
  • The Journal of Physical Chemistry C, Vol. 122, Issue 6
  • DOI: 10.1021/acs.jpcc.7b10297

Mechanism and Kinetics of Hydrogen Peroxide Decomposition on Platinum Nanocatalysts
journal, May 2018

  • Serra-Maia, Rui; Bellier, Marion; Chastka, Stephen
  • ACS Applied Materials & Interfaces, Vol. 10, Issue 25
  • DOI: 10.1021/acsami.8b02345

A Link between Reactivity and Local Structure in Acid Catalysis on Zeolites
journal, April 2008

  • Bhan, Aditya; Iglesia, Enrique
  • Accounts of Chemical Research, Vol. 41, Issue 4
  • DOI: 10.1021/ar700181t

Understanding the Optimal Adsorption Energies for Catalyst Screening in Heterogeneous Catalysis
journal, December 2013

  • Yang, Bo; Burch, Robbie; Hardacre, Christopher
  • ACS Catalysis, Vol. 4, Issue 1
  • DOI: 10.1021/cs400727f

Diffusion of Oriented Single Molecules with Switchable Mobility in Networks of Long Unidimensional Nanochannels
journal, February 2008

  • Jung, Christophe; Kirstein, Johanna; Platschek, Barbara
  • Journal of the American Chemical Society, Vol. 130, Issue 5
  • DOI: 10.1021/ja075927e

Evidence for Crystal-Face-Dependent TiO 2 Photocatalysis from Single-Molecule Imaging and Kinetic Analysis
journal, May 2011

  • Tachikawa, Takashi; Yamashita, Soichiro; Majima, Tetsuro
  • Journal of the American Chemical Society, Vol. 133, Issue 18
  • DOI: 10.1021/ja201415j

Lab-in-a-Shell: Encapsulating Metal Clusters for Size Sieving Catalysis
journal, August 2014

  • Qiao, Zhen-An; Zhang, Pengfei; Chai, Song-Hai
  • Journal of the American Chemical Society, Vol. 136, Issue 32
  • DOI: 10.1021/ja505903r

Mechanistic Aspects of Horseradish Peroxidase Elucidated through Single-Molecule Studies
journal, May 2009

  • Gorris, Hans H.; Walt, David R.
  • Journal of the American Chemical Society, Vol. 131, Issue 17
  • DOI: 10.1021/ja9008858

Quantitative 3D Fluorescence Imaging of Single Catalytic Turnovers Reveals Spatiotemporal Gradients in Reactivity of Zeolite H-ZSM-5 Crystals upon Steaming
journal, April 2015

  • Ristanović, Zoran; Hofmann, Jan P.; De Cremer, Gert
  • Journal of the American Chemical Society, Vol. 137, Issue 20
  • DOI: 10.1021/jacs.5b01698

How Does Confinement Change Ligand–Receptor Binding Equilibrium? Protein Binding in Nanopores and Nanochannels
journal, September 2015

  • Tagliazucchi, Mario; Szleifer, Igal
  • Journal of the American Chemical Society, Vol. 137, Issue 39
  • DOI: 10.1021/jacs.5b05032

Single Molecule Nanospectroscopy Visualizes Proton-Transfer Processes within a Zeolite Crystal
journal, October 2016

  • Ristanović, Zoran; Kubarev, Alexey V.; Hofkens, Johan
  • Journal of the American Chemical Society, Vol. 138, Issue 41
  • DOI: 10.1021/jacs.6b06083

Single-Molecule Fluorescence Microscopy Reveals Local Diffusion Coefficients in the Pore Network of an Individual Catalyst Particle
journal, September 2017

  • Hendriks, Frank C.; Meirer, Florian; Kubarev, Alexey V.
  • Journal of the American Chemical Society, Vol. 139, Issue 39
  • DOI: 10.1021/jacs.7b07139

Molecular Length Dependence of Single Molecule Wobbling within Surfactant- and Solvent-Filled Silica Mesopores
journal, July 2013

  • Pramanik, Rajib; Ito, Takashi; Higgins, Daniel A.
  • The Journal of Physical Chemistry C, Vol. 117, Issue 29
  • DOI: 10.1021/jp404991m

Single-Molecule Tracking Studies of Millimeter-Scale Cylindrical Domain Alignment in Polystyrene–Poly(ethylene oxide) Diblock Copolymer Films Induced by Solvent Vapor Penetration
journal, July 2012

  • Tran-Ba, Khanh-Hoa; Finley, Jason J.; Higgins, Daniel A.
  • The Journal of Physical Chemistry Letters, Vol. 3, Issue 15
  • DOI: 10.1021/jz300647z

How Does a Single Pt Nanocatalyst Behave in Two Different Reactions? A Single-Molecule Study
journal, January 2012

  • Han, Kyu Sung; Liu, Guokun; Zhou, Xiaochun
  • Nano Letters, Vol. 12, Issue 3
  • DOI: 10.1021/nl203677b

Direct Visualization of Dye and Oligonucleotide Diffusion in Silica Filaments with Collinear Mesopores
journal, February 2012

  • Feil, Florian; Cauda, Valentina; Bein, Thomas
  • Nano Letters, Vol. 12, Issue 3
  • DOI: 10.1021/nl2039474

Highly Oriented Mesoporous Silica Channels Synthesized in Microgrooves and Visualized with Single-Molecule Diffusion
journal, February 2012

  • Rühle, Bastian; Davies, Melari; Lebold, Timo
  • ACS Nano, Vol. 6, Issue 3
  • DOI: 10.1021/nn2042835

Kinetics of Proteolytic Reactions in Nanoporous Materials
journal, October 2009

  • Bi, Hongyan; Qiao, Liang; Busnel, Jean-Marc
  • Journal of Proteome Research, Vol. 8, Issue 10
  • DOI: 10.1021/pr9003954

Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization
journal, March 2003

  • Forkey, Joseph N.; Quinlan, Margot E.; Alexander Shaw, M.
  • Nature, Vol. 422, Issue 6930
  • DOI: 10.1038/nature01529

Spatially resolved observation of crystal-face-dependent catalysis by single turnover counting
journal, February 2006

  • Roeffaers, Maarten B. J.; Sels, Bert F.; Uji-i, Hiroshi
  • Nature, Vol. 439, Issue 7076
  • DOI: 10.1038/nature04502

Visualizing single-molecule diffusion in mesoporous materials
journal, November 2007

  • Zürner, Andreas; Kirstein, Johanna; Döblinger, Markus
  • Nature, Vol. 450, Issue 7170, p. 705-708
  • DOI: 10.1038/nature06398

Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes
journal, February 2016

  • Sambur, Justin B.; Chen, Tai-Yen; Choudhary, Eric
  • Nature, Vol. 530, Issue 7588
  • DOI: 10.1038/nature16534

Single-molecule nanocatalysis reveals heterogeneous reaction pathways and catalytic dynamics
journal, November 2008

  • Xu, Weilin; Kong, Jason S.; Yeh, Yun-Ting E.
  • Nature Materials, Vol. 7, Issue 12
  • DOI: 10.1038/nmat2319

Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
journal, August 2006

  • Rust, Michael J.; Bates, Mark; Zhuang, Xiaowei
  • Nature Methods, Vol. 3, Issue 10
  • DOI: 10.1038/nmeth929

Quantitative super-resolution imaging uncovers reactivity patterns on single nanocatalysts
journal, February 2012

  • Zhou, Xiaochun; Andoy, Nesha May; Liu, Guokun
  • Nature Nanotechnology, Vol. 7, Issue 4
  • DOI: 10.1038/nnano.2012.18

Reversible trapping and reaction acceleration within dynamically self-assembling nanoflasks
journal, November 2015

  • Zhao, Hui; Sen, Soumyo; Udayabhaskararao, T.
  • Nature Nanotechnology, Vol. 11, Issue 1
  • DOI: 10.1038/nnano.2015.256

In situ quantitative single-molecule study of dynamic catalytic processes in nanoconfinement
journal, January 2018


The complexity of mesoporous silica nanomaterials unravelled by single molecule microscopy
journal, January 2011

  • Lebold, Timo; Michaelis, Jens; Bräuchle, Christoph
  • Physical Chemistry Chemical Physics, Vol. 13, Issue 11
  • DOI: 10.1039/c0cp02210a

Reactive Monte Carlo and grand-canonical Monte Carlo simulations of the propene metathesis reaction system
journal, April 2005

  • Hansen, Niels; Jakobtorweihen, Sven; Keil, Frerich J.
  • The Journal of Chemical Physics, Vol. 122, Issue 16
  • DOI: 10.1063/1.1884108

Chemical reaction equilibrium in nanoporous materials: NO dimerization reaction in carbon slit nanopores
journal, February 2006

  • Lísal, Martin; Brennan, John K.; Smith, William R.
  • The Journal of Chemical Physics, Vol. 124, Issue 6
  • DOI: 10.1063/1.2171213

Density functional study of chemical reaction equilibrium for dimerization reactions in slit and cylindrical nanopores
journal, April 2009

  • Malijevský, Alexandr; Lísal, Martin
  • The Journal of Chemical Physics, Vol. 130, Issue 16
  • DOI: 10.1063/1.3125925

Understanding nano effects in catalysis
journal, May 2015

  • Yang, Fan; Deng, Dehui; Pan, Xiulian
  • National Science Review, Vol. 2, Issue 2
  • DOI: 10.1093/nsr/nwv024

Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
journal, September 2006


Single-Molecule Investigations of Morphology and Mass Transport Dynamics in Nanostructured Materials
journal, July 2015


Adsorption geometry of benzene on Pd(110): Results of first-principles calculations
journal, December 2000


Works referencing / citing this record:

Single-molecule orientation localization microscopy for resolving structural heterogeneities between amyloid fibrils
journal, January 2020


Figures/Tables have been extracted from DOE-funded journal article accepted manuscripts.