Ultra-selective ligand-driven separation of strategic actinides

Deblonde, Gauthier J. -P.; Ricano, Abel; Abergel, Rebecca J.

doi:10.1038/s41467-019-10240-x

Title: Ultra-selective ligand-driven separation of strategic actinides

Journal Article · 04 June 2019 · Nature Communications

DOI: https://doi.org/10.1038/s41467-019-10240-x · OSTI ID:1619518

^[1]; Ricano, Abel ^[1]; Abergel, Rebecca J. ^[2]

Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States)

Metal ion separations are critical to numerous fields, including nuclear medicine, waste recycling, space exploration, and fundamental research. Nonetheless, operational conditions and performance are limited, imposing compromises between recovery, purity, and cost. Siderophore-inspired ligands show unprecedented charge-based selectivity and compatibility with harsh industry conditions, affording excellent separation efficiency, robustness and process control. Here, we successfully demonstrate a general separation strategy on three distinct systems, for Ac, Pu, and Bk purification. Separation factors (SF) obtained with model compound 3,4,3-LI(1,2-HOPO) are orders of magnitude higher than with any other ligand currently employed: 10⁶ between Ac and relevant metal impurities, and over 10⁸ for redox-free Pu purification against uranyl ions and trivalent actinides or fission products. Finally, a one-step separation method (SF > 3 × 10⁶ and radiopurity > 99.999%) enables the isolation of Bk from adjacent actinides and fission products. The proposed approach offers a paradigm change for the production of strategic elements.

View Journal Article

Cite

Export

Save

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences, and Biosciences Division; USDOE

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1619518

Alternate ID(s):: OSTI ID: 1559224

Journal Information:: Nature Communications, Vol. 10, Issue 1; ISSN 2041-1723

Publisher:: Nature Publishing GroupCopyright Statement

Country of Publication:: United States

Language:: English

Citation Metrics:

Cited by: 37 works

Citation information provided by
Web of Science

References (81)

In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia Hagemann, U. B.; Wickstroem, K.; Wang, E. Molecular Cancer Therapeutics, Vol. 15, Issue 10 https://doi.org/10.1158/1535-7163.MCT-16-0251	journal	August 2016
Recovery of actinides and lanthanides from high-level liquid waste by extraction chromatography using TODGA+TBP impregnated resins Modolo, G.; Asp, H.; Schreinemachers, C. Radiochimica Acta, Vol. 95, Issue 7 https://doi.org/10.1524/ract.2007.95.7.391	journal	January 2007
Spectroscopic and Computational Characterization of Diethylenetriaminepentaacetic Acid/Transplutonium Chelates: Evidencing Heterogeneity in the Heavy Actinide(III) Series Deblonde, Gauthier J. -P.; Kelley, Morgan P.; Su, Jing Angewandte Chemie International Edition, Vol. 57, Issue 17 https://doi.org/10.1002/anie.201709183	journal	March 2018
Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes D’Aléo, Anthony; Moore, Evan G.; Xu, Jide Inorganic Chemistry, Vol. 54, Issue 14 https://doi.org/10.1021/acs.inorgchem.5b00748	journal	July 2015
Applications of MP-1 anion exchange resin and Eichrom LN resin in berkelium-249 purification Du, Miting; Tan, Ryan; Boll, Rose Journal of Radioanalytical and Nuclear Chemistry, Vol. 318, Issue 1 https://doi.org/10.1007/s10967-018-6136-2	journal	August 2018
Fissile Material Stocks and Production, 2008 Glaser, Alexander; Mian, Zia Bulletin of the Atomic Scientists, Vol. 65, Issue 1 https://doi.org/10.2968/065001005	journal	January 2009
Bond Covalency and Oxidation State of Actinide Ions Complexed with Therapeutic Chelating Agent 3,4,3-LI(1,2-HOPO) Kelley, Morgan P.; Deblonde, Gauthier J. -P.; Su, Jing Inorganic Chemistry, Vol. 57, Issue 9 https://doi.org/10.1021/acs.inorgchem.8b00345	journal	April 2018
Solution Thermodynamic Stability of Complexes Formed with the Octadentate Hydroxypyridinonate Ligand 3,4,3-LI(1,2-HOPO): A Critical Feature for Efficient Chelation of Lanthanide(IV) and Actinide(IV) Ions Deblonde, Gauthier J-P.; Sturzbecher-Hoehne, Manuel; Abergel, Rebecca J. Inorganic Chemistry, Vol. 52, Issue 15 https://doi.org/10.1021/ic4010246	journal	July 2013
The size of actinoid(III) ions – structural analysis vs. common misinterpretations Lundberg, Daniel; Persson, Ingmar Coordination Chemistry Reviews, Vol. 318 https://doi.org/10.1016/j.ccr.2016.04.003	journal	July 2016
Solution thermodynamic evaluation of hydroxypyridinonate chelators 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO) for UO ₂ (VI) and Th(IV) decorporation Sturzbecher-Hoehne, M.; Deblonde, G. J. -P.; Abergel, R. J. Radiochimica Acta, Vol. 101, Issue 6 https://doi.org/10.1524/ract.2013.2047	journal	June 2013
Distribution of plutonium, americium and interfering fission products between nitric acid and a mixed organic phase of TODGA and DMDOHEMA in kerosene, and implications for the design of the “EURO-GANEX” process Carrott, Michael; Geist, Andreas; Hères, Xavier Hydrometallurgy, Vol. 152 https://doi.org/10.1016/j.hydromet.2014.12.019	journal	February 2015
Solution thermodynamic evaluation of hydroxypyridinonate chelators 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO) for UO ₂ (VI) and Th(IV) decorporation Sturzbecher-Hoehne, M.; Deblonde, G. J. -P.; Abergel, R. J. Radiochimica Acta, Vol. 101, Issue 6 https://doi.org/10.1524/ract.2013.2047	journal	June 2013
The Chemistry of TALSPEAK: A Review of the Science Nash, Kenneth L. Solvent Extraction and Ion Exchange, Vol. 33, Issue 1 https://doi.org/10.1080/07366299.2014.985912	journal	December 2014
Highly Luminescent and Stable Hydroxypyridinonate Complexes: A Step Towards New Curium Decontamination Strategies Sturzbecher-Hoehne, Manuel; Kullgren, Birgitta; Jarvis, Erin E. Chemistry - A European Journal, Vol. 20, Issue 32 https://doi.org/10.1002/chem.201402103	journal	July 2014
Solution Thermodynamic Stability of Complexes Formed with the Octadentate Hydroxypyridinonate Ligand 3,4,3-LI(1,2-HOPO): A Critical Feature for Efficient Chelation of Lanthanide(IV) and Actinide(IV) Ions Deblonde, Gauthier J-P.; Sturzbecher-Hoehne, Manuel; Abergel, Rebecca J. Inorganic Chemistry, Vol. 52, Issue 15 https://doi.org/10.1021/ic4010246	journal	July 2013
Applications of MP-1 anion exchange resin and Eichrom LN resin in berkelium-249 purification Du, Miting; Tan, Ryan; Boll, Rose Journal of Radioanalytical and Nuclear Chemistry, Vol. 318, Issue 1 https://doi.org/10.1007/s10967-018-6136-2	journal	August 2018
A Macrocyclic Chelator That Selectively Binds Ln ⁴⁺ over Ln ³⁺ by a Factor of 10 ²⁹ Pham, Tiffany A.; Altman, Alison B.; Stieber, S. Chantal E. Inorganic Chemistry, Vol. 55, Issue 20 https://doi.org/10.1021/acs.inorgchem.6b00684	journal	June 2016
Spectroscopic and Computational Characterization of Diethylenetriaminepentaacetic Acid/Transplutonium Chelates: Evidencing Heterogeneity in the Heavy Actinide(III) Series Deblonde, Gauthier J. -P.; Kelley, Morgan P.; Su, Jing Angewandte Chemie International Edition, Vol. 57, Issue 17 https://doi.org/10.1002/anie.201709183	journal	March 2018
Advancing Understanding of the +4 Metal Extractant Thenoyltrifluoroacetonate (TTA ^– ); Synthesis and Structure of M ^IV TTA ₄ (M ^IV = Zr, Hf, Ce, Th, U, Np, Pu) and M ^III (TTA) ₄ ^– (M ^III = Ce, Nd, Sm, Yb) Cary, Samantha K.; Livshits, Maksim; Cross, Justin N. Inorganic Chemistry, Vol. 57, Issue 7 https://doi.org/10.1021/acs.inorgchem.7b03089	journal	December 2017
3,4,3-LI(1,2-HOPO): In vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation Sturzbecher-Hoehne, Manuel; Ng Pak Leung, Clara; D'Aléo, Anthony Dalton Transactions, Vol. 40, Issue 33 https://doi.org/10.1039/c1dt10840a	journal	January 2011
Intramolecular sensitization of americium luminescence in solution: shining light on short-lived forbidden 5f transitions Sturzbecher-Hoehne, M.; Yang, P.; D'Aléo, A. Dalton Transactions, Vol. 45, Issue 24 https://doi.org/10.1039/C6DT00328A	journal	January 2016
Spectroscopic and Computational Characterization of Diethylenetriaminepentaacetic Acid/Transplutonium Chelates: Evidencing Heterogeneity in the Heavy Actinide(III) Series Deblonde, Gauthier J. -P.; Kelley, Morgan P.; Su, Jing Angewandte Chemie, Vol. 130, Issue 17 https://doi.org/10.1002/ange.201709183	journal	March 2018
Solution Thermodynamics and Kinetics of Metal Complexation with a Hydroxypyridinone Chelator Designed for Thorium-227 Targeted Alpha Therapy Deblonde, Gauthier J. -P.; Lohrey, Trevor D.; Booth, Corwin H. Inorganic Chemistry, Vol. 57, Issue 22 https://doi.org/10.1021/acs.inorgchem.8b02430	journal	October 2018
Alternatives to HDEHP and DTPA for Simplified TALSPEAK Separations Braley, Jenifer C.; Grimes, Travis S.; Nash, Kenneth L. Industrial & Engineering Chemistry Research, Vol. 51, Issue 2 https://doi.org/10.1021/ie200285r	journal	June 2011
Applications of Diglycolamide Based Solvent Extraction Processes in Spent Nuclear Fuel Reprocessing, Part 1: TODGA Whittaker, Daniel; Geist, Andreas; Modolo, Giuseppe Solvent Extraction and Ion Exchange, Vol. 36, Issue 3 https://doi.org/10.1080/07366299.2018.1464269	journal	April 2018
Cumulative study on solvent extraction of elements by N,N,N′,N′-tetraoctyl-3-oxapentanediamide (TODGA) from nitric acid into n-dodecane Zhu, Zhi-Xuan; Sasaki, Yuji; Suzuki, Hideya Analytica Chimica Acta, Vol. 527, Issue 2 https://doi.org/10.1016/j.aca.2004.09.023	journal	December 2004
Alternatives to HDEHP and DTPA for Simplified TALSPEAK Separations Braley, Jenifer C.; Grimes, Travis S.; Nash, Kenneth L. Industrial & Engineering Chemistry Research, Vol. 51, Issue 2 https://doi.org/10.1021/ie200285r	journal	June 2011
Recovery of Uranium from Wet Phosphoric Acid by Solvent Extraction Processes Beltrami, Denis; Cote, Gérard; Mokhtari, Hamid Chemical Reviews, Vol. 114, Issue 24 https://doi.org/10.1021/cr5001546	journal	November 2014
Rare earth separations by selective borate crystallization Yin, Xuemiao; Wang, Yaxing; Bai, Xiaojing Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/ncomms14438	journal	March 2017
Chemical separations for super-heavy element searches in irradiated uranium targets Horwitz, E. P.; Bloomquist, C. A. A. Journal of Inorganic and Nuclear Chemistry, Vol. 37, Issue 2 https://doi.org/10.1016/0022-1902(75)80350-2	journal	February 1975
Evaluation of DFO-HOPO as an octadentate chelator for zirconium-89 Allott, L.; Da Pieve, C.; Meyers, J. Chemical Communications, Vol. 53, Issue 61 https://doi.org/10.1039/C7CC03572A	journal	January 2017
Evaluation of nitrogen-rich macrocyclic ligands for the chelation of therapeutic bismuth radioisotopes Wilson, Justin J.; Ferrier, Maryline; Radchenko, Valery Nuclear Medicine and Biology, Vol. 42, Issue 5 https://doi.org/10.1016/j.nucmedbio.2014.12.007	journal	May 2015
Fissile Material Stocks and Production, 2008 Glaser, Alexander; Mian, Zia Bulletin of the Atomic Scientists, Vol. 65, Issue 1 https://doi.org/10.2968/065001005	journal	January 2009
Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes Radchenko, V.; Engle, J. W.; Wilson, J. J. Journal of Chromatography A, Vol. 1380, p. 55-63 https://doi.org/10.1016/j.chroma.2014.12.045	journal	February 2015
Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator–Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms Captain, Ilya; Deblonde, Gauthier J. -P.; Rupert, Peter B. Inorganic Chemistry, Vol. 55, Issue 22 https://doi.org/10.1021/acs.inorgchem.6b02041	journal	November 2016
Development of a TODGA based Process for Partitioning of Actinides from a PUREX Raffinate Part I: Batch Extraction Optimization Studies and Stability Tests Modolo, Giuseppe; Asp, Hanna; Schreinemachers, Christian Solvent Extraction and Ion Exchange, Vol. 25, Issue 6 https://doi.org/10.1080/07366290701634578	journal	October 2007
Highly Luminescent and Stable Hydroxypyridinonate Complexes: A Step Towards New Curium Decontamination Strategies Sturzbecher-Hoehne, Manuel; Kullgren, Birgitta; Jarvis, Erin E. Chemistry - A European Journal, Vol. 20, Issue 32 https://doi.org/10.1002/chem.201402103	journal	July 2014
Facile and Efficient Decontamination of Thorium from Rare Earths Based on Selective Selenite Crystallization Wang, Yaxing; Lu, Huangjie; Dai, Xing Inorganic Chemistry, Vol. 57, Issue 4 https://doi.org/10.1021/acs.inorgchem.7b02681	journal	February 2018
Rational Design of Sequestering Agents for Plutonium and Other Actinides Gorden, Anne E. V.; Xu, Jide; Raymond, Kenneth N. Chemical Reviews, Vol. 103, Issue 11 https://doi.org/10.1021/cr990114x	journal	November 2003
Synthesis and Initial Evaluation for In Vivo Chelation of Pu(IV) of a Mixed Octadentate Spermine-Based Ligand Containing 4-Carbamoyl-3-hydroxy-1-methyl-2(1 H )-pyridinone and 6-Carbamoyl-1-hydroxy-2(1 H )-pyridinone Xu, Jide; Durbin, Patricia W.; Kullgren, Birgitta Journal of Medicinal Chemistry, Vol. 45, Issue 18 https://doi.org/10.1021/jm010564t	journal	August 2002
Synthesis and Initial Evaluation for In Vivo Chelation of Pu(IV) of a Mixed Octadentate Spermine-Based Ligand Containing 4-Carbamoyl-3-hydroxy-1-methyl-2(1 H )-pyridinone and 6-Carbamoyl-1-hydroxy-2(1 H )-pyridinone Xu, Jide; Durbin, Patricia W.; Kullgren, Birgitta Journal of Medicinal Chemistry, Vol. 45, Issue 18 https://doi.org/10.1021/jm010564t	journal	August 2002
Applications of Diglycolamide Based Solvent Extraction Processes in Spent Nuclear Fuel Reprocessing, Part 1: TODGA Whittaker, Daniel; Geist, Andreas; Modolo, Giuseppe Taylor & Francis https://doi.org/10.6084/m9.figshare.6326006	text	January 2018
Synthesis and Characterization of the Actinium Aquo Ion Ferrier, Maryline G.; Stein, Benjamin W.; Batista, Enrique R. ACS Central Science, Vol. 3, Issue 3 https://doi.org/10.1021/acscentsci.6b00356	journal	February 2017
Rare earth separations by selective borate crystallization Yin, Xuemiao; Wang, Yaxing; Bai, Xiaojing Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/ncomms14438	journal	March 2017
Chelation and stabilization of berkelium in oxidation state +IV Deblonde, Gauthier J. -P.; Sturzbecher-Hoehne, Manuel; Rupert, Peter B. Nature Chemistry, Vol. 9, Issue 9 https://doi.org/10.1038/nchem.2759	journal	April 2017
Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator–Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms Captain, Ilya; Deblonde, Gauthier J. -P.; Rupert, Peter B. Inorganic Chemistry, Vol. 55, Issue 22 https://doi.org/10.1021/acs.inorgchem.6b02041	journal	November 2016
Development of a TODGA based Process for Partitioning of Actinides from a PUREX Raffinate Part I: Batch Extraction Optimization Studies and Stability Tests Modolo, Giuseppe; Asp, Hanna; Schreinemachers, Christian Solvent Extraction and Ion Exchange, Vol. 25, Issue 6 https://doi.org/10.1080/07366290701634578	journal	October 2007
Rational Design of Sequestering Agents for Plutonium and Other Actinides Gorden, Anne E. V.; Xu, Jide; Raymond, Kenneth N. Chemical Reviews, Vol. 103, Issue 11 https://doi.org/10.1021/cr990114x	journal	November 2003
Plutonium(IV) Sequestration: Structural and Thermodynamic Evaluation of the Extraordinarily Stable Cerium(IV) Hydroxypyridinonate Complexes¹ Xu, Jide; Radkov, Emil; Ziegler, Marco Inorganic Chemistry, Vol. 39, Issue 18, p. 4156-4164 https://doi.org/10.1021/ic000063i	journal	September 2000
Recovery of uranium (VI) from concentrated phosphoric acid using bifunctional reagents Leydier, Antoine; Arrachart, Guilhem; Turgis, Raphaël Hydrometallurgy, Vol. 171 https://doi.org/10.1016/j.hydromet.2017.05.008	journal	August 2017
Actinide targets for the synthesis of super-heavy elements Roberto, J. B.; Alexander, C. W.; Boll, R. A. Nuclear Physics A, Vol. 944 https://doi.org/10.1016/j.nuclphysa.2015.06.009	journal	December 2015
Applications of Diglycolamide Based Solvent Extraction Processes in Spent Nuclear Fuel Reprocessing, Part 1: TODGA Whittaker, Daniel; Geist, Andreas; Modolo, Giuseppe Taylor & Francis https://doi.org/10.6084/m9.figshare.6326006.v1	text	January 2018
Synthesis and Characterization of the Actinium Aquo Ion Ferrier, Maryline G.; Stein, Benjamin W.; Batista, Enrique R. ACS Central Science, Vol. 3, Issue 3 https://doi.org/10.1021/acscentsci.6b00356	journal	February 2017
Plutonium(IV) and (V) Sorption to Goethite at Sub-Femtomolar to Micromolar Concentrations: Redox Transformations and Surface Precipitation Zhao, Pihong; Begg, James D.; Zavarin, Mavrik Environmental Science & Technology, Vol. 50, Issue 13 https://doi.org/10.1021/acs.est.6b00605	journal	June 2016
Nuclear power: Desperately seeking plutonium Witze, Alexandra Nature, Vol. 515, Issue 7528 https://doi.org/10.1038/515484a	journal	November 2014
Standard and advanced separation: PUREX processes for nuclear fuel reprocessing Herbst, R. S.; Baron, P.; Nilsson, M. Advanced Separation Techniques for Nuclear Fuel Reprocessing and Radioactive Waste Treatment https://doi.org/10.1533/9780857092274.2.141	book	January 2011
Biomimetic Actinide Chelators: an Update on the Preclinical Development of the Orally Active Hydroxypyridonate Decorporation Agents 3,4,3-Li(1,2-Hopo) and 5-Lio(Me-3,2-Hopo) Abergel, Rebecca J.; Durbin, Patricia W.; Kullgren, Birgitta Health Physics, Vol. 99, Issue 3 https://doi.org/10.1097/HP.0b013e3181c21273	journal	January 2010
3,4,3-LI(1,2-HOPO): In vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation Sturzbecher-Hoehne, Manuel; Ng Pak Leung, Clara; D'Aléo, Anthony Dalton Transactions, Vol. 40, Issue 33 https://doi.org/10.1039/c1dt10840a	journal	January 2011
p -SCN-Bn-HOPO: A Superior Bifunctional Chelator for ⁸⁹ Zr ImmunoPET Deri, Melissa A.; Ponnala, Shashikanth; Kozlowski, Paul Bioconjugate Chemistry, Vol. 26, Issue 12 https://doi.org/10.1021/acs.bioconjchem.5b00572	journal	November 2015
Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes Radchenko, V.; Engle, J. W.; Wilson, J. J. Journal of Chromatography A, Vol. 1380, p. 55-63 https://doi.org/10.1016/j.chroma.2014.12.045	journal	February 2015
Separation of actinides from spent nuclear fuel: A review Veliscek-Carolan, Jessica Journal of Hazardous Materials, Vol. 318 https://doi.org/10.1016/j.jhazmat.2016.07.027	journal	November 2016
Nuclear power: Desperately seeking plutonium Witze, Alexandra Nature, Vol. 515, Issue 7528 https://doi.org/10.1038/515484a	journal	November 2014
Rational Design of Sequestering Agents for Plutonium and Other Actinides Gorden, Anne E. V.; Xu, Jide; Raymond, Kenneth N. ChemInform, Vol. 35, Issue 5 https://doi.org/10.1002/chin.200405275	journal	February 2004
Chemical separations for super-heavy element searches in irradiated uranium targets Horwitz, E. P.; Bloomquist, C. A. A. Journal of Inorganic and Nuclear Chemistry, Vol. 37, Issue 2 https://doi.org/10.1016/0022-1902(75)80350-2	journal	February 1975
Names and symbols of the elements with atomic numbers 113, 115, 117 and 118 (IUPAC Recommendations 2016) Öhrström, Lars; Reedijk, Jan Pure and Applied Chemistry, Vol. 88, Issue 12 https://doi.org/10.1515/pac-2016-0501	journal	December 2016
p -SCN-Bn-HOPO: A Superior Bifunctional Chelator for ⁸⁹ Zr ImmunoPET Deri, Melissa A.; Ponnala, Shashikanth; Kozlowski, Paul Bioconjugate Chemistry, Vol. 26, Issue 12 https://doi.org/10.1021/acs.bioconjchem.5b00572	journal	November 2015
Separation of actinides from spent nuclear fuel: A review Veliscek-Carolan, Jessica Journal of Hazardous Materials, Vol. 318 https://doi.org/10.1016/j.jhazmat.2016.07.027	journal	November 2016
Solution Thermodynamics and Kinetics of Metal Complexation with a Hydroxypyridinone Chelator Designed for Thorium-227 Targeted Alpha Therapy Deblonde, Gauthier J. -P.; Lohrey, Trevor D.; Booth, Corwin H. Inorganic Chemistry, Vol. 57, Issue 22 https://doi.org/10.1021/acs.inorgchem.8b02430	journal	October 2018
Evaluation of nitrogen-rich macrocyclic ligands for the chelation of therapeutic bismuth radioisotopes Wilson, Justin J.; Ferrier, Maryline; Radchenko, Valery Nuclear Medicine and Biology, Vol. 42, Issue 5 https://doi.org/10.1016/j.nucmedbio.2014.12.007	journal	May 2015
The Chemistry of TALSPEAK: A Review of the Science Nash, Kenneth L. Solvent Extraction and Ion Exchange, Vol. 33, Issue 1 https://doi.org/10.1080/07366299.2014.985912	journal	December 2014
Distribution of plutonium, americium and interfering fission products between nitric acid and a mixed organic phase of TODGA and DMDOHEMA in kerosene, and implications for the design of the “EURO-GANEX” process Carrott, Michael; Geist, Andreas; Hères, Xavier Hydrometallurgy, Vol. 152 https://doi.org/10.1016/j.hydromet.2014.12.019	journal	February 2015
Plutonium(IV) and (V) Sorption to Goethite at Sub-Femtomolar to Micromolar Concentrations: Redox Transformations and Surface Precipitation Zhao, Pihong; Begg, James D.; Zavarin, Mavrik Environmental Science & Technology, Vol. 50, Issue 13 https://doi.org/10.1021/acs.est.6b00605	journal	June 2016
Toxic heavy metal – Pb, Cd, Sn – complexation by the octadentate hydroxypyridinonate ligand archetype 3,4,3-LI(1,2-HOPO) Deblonde, Gauthier J. -P.; Lohrey, Trevor D.; An, Dahlia D. New Journal of Chemistry, Vol. 42, Issue 10 https://doi.org/10.1039/C7NJ04559J	journal	January 2018
A Macrocyclic Chelator That Selectively Binds Ln ⁴⁺ over Ln ³⁺ by a Factor of 10 ²⁹ Pham, Tiffany A.; Altman, Alison B.; Stieber, S. Chantal E. Inorganic Chemistry, Vol. 55, Issue 20 https://doi.org/10.1021/acs.inorgchem.6b00684	journal	June 2016
Cumulative study on solvent extraction of elements by N,N,N′,N′-tetraoctyl-3-oxapentanediamide (TODGA) from nitric acid into n-dodecane Zhu, Zhi-Xuan; Sasaki, Yuji; Suzuki, Hideya Analytica Chimica Acta, Vol. 527, Issue 2 https://doi.org/10.1016/j.aca.2004.09.023	journal	December 2004
The size of actinoid(III) ions – structural analysis vs. common misinterpretations Lundberg, Daniel; Persson, Ingmar Coordination Chemistry Reviews, Vol. 318 https://doi.org/10.1016/j.ccr.2016.04.003	journal	July 2016
Recovery of uranium (VI) from concentrated phosphoric acid using bifunctional reagents Leydier, Antoine; Arrachart, Guilhem; Turgis, Raphaël Hydrometallurgy, Vol. 171 https://doi.org/10.1016/j.hydromet.2017.05.008	journal	August 2017
Applications of Diglycolamide Based Solvent Extraction Processes in Spent Nuclear Fuel Reprocessing, Part 1: TODGA Whittaker, Daniel; Geist, Andreas; Modolo, Giuseppe Solvent Extraction and Ion Exchange, Vol. 36, Issue 3 https://doi.org/10.1080/07366299.2018.1464269	journal	April 2018
Chelation and stabilization of berkelium in oxidation state +IV Deblonde, Gauthier J. -P.; Sturzbecher-Hoehne, Manuel; Rupert, Peter B. Nature Chemistry, Vol. 9, Issue 9 https://doi.org/10.1038/nchem.2759	journal	April 2017
Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes D’Aléo, Anthony; Moore, Evan G.; Xu, Jide Inorganic Chemistry, Vol. 54, Issue 14 https://doi.org/10.1021/acs.inorgchem.5b00748	journal	July 2015
Experimental studies of the 249 Bk + 48 Ca reaction including decay properties and excitation function for isotopes of element 117, and discovery of the new isotope 277 Mt Oganessian, Yu. Ts.; Abdullin, F. Sh.; Alexander, C. Physical Review C, Vol. 87, Issue 5 https://doi.org/10.1103/PhysRevC.87.054621	journal	May 2013

Cited By (2)

A light activated CMP conjugated 8-aminoquinoline turn-on fluorescent optode for selective determination of Th ⁴⁺ in an aqueous environment Kumar R., Selva; Ashok Kumar, S. K. Dalton Transactions, Vol. 48, Issue 33 https://doi.org/10.1039/c9dt01830a	journal	January 2019
Iodine Adsorption in a Redox-Active Metal–Organic Framework: Electrical Conductivity Induced by Host−Guest Charge-Transfer Zhang, Xinran; da Silva, Ivan; Fazzi, Rodrigo Inorganic Chemistry, Vol. 58, Issue 20 https://doi.org/10.1021/acs.inorgchem.9b02176	journal	September 2019

Similar Records

Hydroxypyridinone Derivatives: A Low-pH Alternative to Polyaminocarboxylates for TALSPEAK-like Separation of Trivalent Actinides from Lanthanides

Journal Article · 2020 · ACS Omega · OSTI ID:1631338

Wang, Yufei; Deblonde, Gauthier J.-P.; Abergel, Rebecca J.

Specific sequestering agents for the actinides

Conference · 1980 · ACS Symp. Ser.; (United States) · OSTI ID:6408653

Raymond, K N; Smith, W L; Weitl, F L; +5 more

Biomimetic Actinide Chelators: An Update on the Preclinical Development of the Orally Active Hydroxypyridonate Decorporation Agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO)

Journal Article · 2011 · Health Physics · OSTI ID:1048305

Durbin, Patricia W; Kullgren, Birgitta; Ebbe, Shirley N; +8 more

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Title: Ultra-selective ligand-driven separation of strategic actinides

Citation Formats

References (81)

Cited By (2)

Similar Records

Related Subjects