No-touch measurements of vital signs in small conscious animals

Hui, Xiaonan; Kan, Edwin C.

doi:10.1126/sciadv.aau0169

Title: No-touch measurements of vital signs in small conscious animals

Journal Article · 12 February 2019 · Science Advances

DOI: https://doi.org/10.1126/sciadv.aau0169 · OSTI ID:1613634

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Cornell Univ., Ithaca, NY (United States); DOE/OSTI
Cornell Univ., Ithaca, NY (United States)

Measuring the heartbeat and respiration of small conscious animals is important for assessing their health and behavior, but present techniques such as electrocardiogram (ECG), ultrasound, and auscultation rely on close skin contact with the animal. These methods can also require surface preparation, cause discomfort or stress to animals, and even require anesthetic administration, especially for birds, reptiles, and fish. Here, we show that radio frequency near-field coherent sensing (NCS) can provide a new solution to animal vital sign monitoring while ensuring minimal pain and distress. We first benchmarked NCS with synchronous ECG on an anesthetized rat. NCS was then applied to monitor a conscious hamster from outside its cage, and was further extended to a parakeet, Russian tortoise, and betta fish in a noninvasive manner. Our system can revolutionize vital sign monitoring of small conscious animals in their laboratory living quarters or natural habitats.

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Research Organization:: Cornell Univ., Ithaca, NY (United States)

Sponsoring Organization:: USDOE Advanced Research Projects Agency - Energy (ARPA-E)

Grant/Contract Number:: AR0000528; AR0000946

OSTI ID:: 1613634

Journal Information:: Science Advances, Journal Name: Science Advances Journal Issue: 2 Vol. 5; ISSN 2375-2548

Publisher:: AAASCopyright Statement

Country of Publication:: United States

Language:: English

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