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Title: Lignin–Enzyme Interactions in the Hydrolysis of Lignocellulosic Biomass

Journal Article · · Trends in Biotechnology
 [1];  [2];  [3]; ORCiD logo [2]
  1. Purdue Univ., West Lafayette, IN (United States); DOE/OSTI
  2. Purdue Univ., West Lafayette, IN (United States)
  3. Univ. of Wisconsin, River Falls, WI (United States)

Lignin is central to overcoming recalcitrance in the enzyme hydrolysis of lignocellulose. While the term implies a physical barrier in the cell wall structure, there are also important biochemical components that direct interactions between lignin and the hydrolytic enzymes that attack cellulose in plant cell walls. Progress toward a deeper understanding of the lignin synthesis pathway – and the consistency between a range of observations over the past 40 years in the very extensive literature on cellulose hydrolysis – is resulting in advances in reducing a major impediment to cellulose conversion: the cost of enzymes. This review addresses lignin and its role in the hydrolysis of hardwood and other lignocellulosic residues.

Research Organization:
Purdue Univ., West Lafayette, IN (United States)
Sponsoring Organization:
USDOE Office of Energy Efficiency and Renewable Energy (EERE), Transportation Office. Bioenergy Technologies Office
Grant/Contract Number:
EE0008256
OSTI ID:
1613512
Journal Information:
Trends in Biotechnology, Journal Name: Trends in Biotechnology Journal Issue: 5 Vol. 37; ISSN 0167-7799
Publisher:
ElsevierCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (14)

Enzymatic sugar production from elephant grass and reed straw through pretreatments and hydrolysis with addition of thioredoxin-His-S journal December 2019
Additional file 2 of Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei dataset January 2022
Additional file 3 of Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei dataset January 2022
Additional file 4 of Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei dataset January 2022
Additional file 5 of Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei dataset January 2022
Impact of protein blocking on enzymatic saccharification of bagasse from sugarcane clones journal March 2019
Adaptive laboratory evolution of nanocellulose‐producing bacterium journal May 2019
Enzymatic saccharification of banana peel and sequential fermentation of the reducing sugars to produce lactic acid journal November 2019
Improved Cellulosic Ethanol Titres from Highly Lignified Cotton Trash Residues Using Various Batch and Fed-Batch Process Configurations journal August 2019
Effect of Sodium Hydroxide Pretreatment on Lignin Monomeric Components of Miscanthus × giganteus and Enzymatic Hydrolysis journal October 2019
Effect of cellulolytic enzyme binding on lignin isolated from alkali and acid pretreated switchgrass on enzymatic hydrolysis journal November 2019
Pectin-derived immune elicitors in response to lignin modification in plants journal February 2020
Enzymatic sugar production from elephant grass and reed straw through pretreatments and hydrolysis with addition of thioredoxin-His-S journal December 2019
Effect of Lignin Content on Cellulolytic Saccharification of Liquid Hot Water Pretreated Sugarcane Bagasse journal January 2020

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