Carbon/Nitrogen Metabolic Balance: Lessons from Cyanobacteria

Zhang, Cheng-Cai; Zhou, Cong-Zhao; Burnap, Robert L.; Peng, Ling

doi:10.1016/j.tplants.2018.09.008

Title: Carbon/Nitrogen Metabolic Balance: Lessons from Cyanobacteria

Journal Article · 02 October 2018 · Trends in Plant Science

DOI: https://doi.org/10.1016/j.tplants.2018.09.008 · OSTI ID:1609961

Zhang, Cheng-Cai ^[1]; Zhou, Cong-Zhao ^[2]; Burnap, Robert L. ^[3]; Peng, Ling ^[4]

Chinese Academy of Sciences (CAS), Wuhan (China); Aix-Marseille Univ., Marseille (France); DOE/OSTI
Univ. of Science and Technology of China, Hefei (China)
Oklahoma State Univ., Stillwater, OK (United States)
Aix-Marseille Univ., Marseille (France)

Carbon and nitrogen are the two most abundant nutrient elements for all living organisms, and their metabolism is tightly coupled. What are the signaling mechanisms that cells use to sense and control the carbon/nitrogen (C/N) metabolic balance following environmental changes? Based on studies in cyanobacteria, it was found that 2-phosphoglycolate derived from the oxygenase activity of Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) and 2-oxoglutarate from the Krebs cycle act as the carbon- and nitrogen-starvation signals, respectively, and their concentration ratio likely reflects the status of the C/N metabolic balance. We will present and discuss the regulatory principles underlying the signaling mechanisms, which are likely to be conserved in other photosynthetic organisms. These concepts may also contribute to developments in the field of biofuel engineering or improvements in crop productivity.

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Research Organization:: Oklahoma State Univ., Stillwater, OK (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: FG02-08ER15968

OSTI ID:: 1609961

Journal Information:: Trends in Plant Science, Journal Name: Trends in Plant Science Journal Issue: 12 Vol. 23; ISSN 1360-1385

Publisher:: Cell PressCopyright Statement

Country of Publication:: United States

Language:: English

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