Selection Signatures Underlying Dramatic Male Inflorescence Transformation During Modern Hybrid Maize Breeding

Gage, Joseph L.; White, Michael R.; Edwards, Jode W.; Kaeppler, Shawn; de Leon, Natalia

doi:10.1534/genetics.118.301487

Title: Selection Signatures Underlying Dramatic Male Inflorescence Transformation During Modern Hybrid Maize Breeding

Journal Article · 24 September 2018 · Genetics (Online)

DOI: https://doi.org/10.1534/genetics.118.301487 · OSTI ID:1609250

^[1]; White, Michael R. ^[2]; Edwards, Jode W. ^[3]; Kaeppler, Shawn ^[2];

^[2]

Univ. of Wisconsin, Madison, WI (United States); DOE/OSTI
Univ. of Wisconsin, Madison, WI (United States)
Iowa State Univ., Ames, IA (United States)

Inflorescence capacity plays a crucial role in reproductive fitness in plants, and in production of hybrid crops. Maize is a monoecious species bearing separate male and female flowers (tassel and ear, respectively). The switch from open-pollinated populations of maize to hybrid-based breeding schemes in the early 20th century was accompanied by a dramatic reduction in tassel size, and the trend has continued with modern breeding over the recent decades. The goal of this study was to identify selection signatures in genes that may underlie this dramatic transformation. Using a population of 942 diverse inbred maize accessions and a nested association mapping population comprising three 200-line biparental populations, we measured 15 tassel morphological characteristics by manual and image-based methods. Genome-wide association studies identified 242 single nucleotide polymorphisms significantly associated with measured traits. We compared 41 unselected lines from the Iowa Stiff Stalk Synthetic (BSSS) population to 21 highly selected lines developed by modern commercial breeding programs, and found that tassel size and weight were reduced significantly. We assayed genetic differences between the two groups using three selection statistics: cross population extended haplotype homozogysity, cross-population composite likelihood ratio, and fixation index. All three statistics show evidence of selection at genomic regions associated with tassel morphology relative to genome-wide null distributions. These results support the tremendous effect, both phenotypic and genotypic, that selection has had on maize male inflorescence morphology.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Univ. of Wisconsin, Madison, WI (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

Grant/Contract Number:: AC02-05CH11231; FC02-07ER64494

OSTI ID:: 1609250

Journal Information:: Genetics (Online), Journal Name: Genetics (Online) Journal Issue: 3 Vol. 210; ISSN 1943-2631

Publisher:: Oxford University Press; Genetics Society of AmericaCopyright Statement

Country of Publication:: United States

Language:: English

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Cited By (3)

Comparing Genome-Wide Association Study Results from Different Measurements of an Underlying Phenotype Gage, Joseph L.; de Leon, Natalia; Clayton, Murray K. G3: Genes\|Genomes\|Genetics, Vol. 8, Issue 11 https://doi.org/10.1534/g3.118.200700	journal	September 2018
Data from: Selection signatures underlying dramatic male inflorescence transformation during modern hybrid maize breeding Gage, Joseph L.; White, Michael R.; Edwards, Jode W. Dryad https://doi.org/10.5061/dryad.6tg35t6	dataset	January 2018
Data from: Selection signatures underlying dramatic male inflorescence transformation during modern hybrid maize breeding Gage, Joseph L.; White, Michael R.; Edwards, Jode W. Dryad https://doi.org/10.5061/dryad.6tg35t6	dataset	January 2018

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
GWAS
genetics & heredity
inflorescence
maize
selection
tassel

Supplemental Material for Gage et al., 2018 Gage, Joseph L.; White, Michael R.; Edwards, Jode W. https://doi.org/10.25386/genetics.7097813.v1 The current record is supplemented by this collection	collection	January 2018
Data from: Selection signatures underlying dramatic male inflorescence transformation during modern hybrid maize breeding Gage, Joseph L.; White, Michael R.; Edwards, Jode W. https://doi.org/10.5061/dryad.6tg35t6 The current record is supplemented by this dataset	dataset	January 2018