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Title: Data filtering method for correlated X-ray scattering (CXS)

Abstract

Correlated X-ray scattering (CXS) which was explored to study the conformations of biological macromolecules in solution was studied further in this paper. In our experiment, three kinds of solution sample such as the Peg solution, the linear DNA from salmon sperm and the plasmid DNA were scattered by X-ray Free Electron Laser in Spring8 in Japan. And the X-ray scattering patterns with low rate of signal and noise were obtained. In order to improve the correlated signal, a cluster data filtering method for billions of scattering patterns was put forward. Finally, some of the scattering patterns with high artifacts which were related with potential sources of experimental set-up had been characterized and removed. In addition, different clusters were clarified so as to compute and analyze the angular autocorrelation of different clusters more effectively.

Authors:
 [1];  [2]
  1. Department of Electronic and Information Engineering, Xiamen City University, 1263 Qianpu Road, Siming District, Xiamen 361008, China
  2. Department of Applied Physics, Stanford University, Stanford, CA 94305, USA; SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA
Publication Date:
Research Org.:
SLAC National Accelerator Lab., Menlo Park, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1605177
Grant/Contract Number:  
AC02-76SF00515; 251 R01-GM097463; 5T32GM008412-20; AC02-05CH11231; 11547238
Resource Type:
Accepted Manuscript
Journal Name:
Modern Physics Letters B
Additional Journal Information:
Journal Volume: 34; Journal Issue: 02; Journal ID: ISSN 0217-9849
Country of Publication:
United States
Language:
English

Citation Formats

Liu, Shengjun, and Schenk, Gundolf. Data filtering method for correlated X-ray scattering (CXS). United States: N. p., 2019. Web. doi:10.1142/s0217984920500189.
Liu, Shengjun, & Schenk, Gundolf. Data filtering method for correlated X-ray scattering (CXS). United States. doi:10.1142/s0217984920500189.
Liu, Shengjun, and Schenk, Gundolf. Tue . "Data filtering method for correlated X-ray scattering (CXS)". United States. doi:10.1142/s0217984920500189.
@article{osti_1605177,
title = {Data filtering method for correlated X-ray scattering (CXS)},
author = {Liu, Shengjun and Schenk, Gundolf},
abstractNote = {Correlated X-ray scattering (CXS) which was explored to study the conformations of biological macromolecules in solution was studied further in this paper. In our experiment, three kinds of solution sample such as the Peg solution, the linear DNA from salmon sperm and the plasmid DNA were scattered by X-ray Free Electron Laser in Spring8 in Japan. And the X-ray scattering patterns with low rate of signal and noise were obtained. In order to improve the correlated signal, a cluster data filtering method for billions of scattering patterns was put forward. Finally, some of the scattering patterns with high artifacts which were related with potential sources of experimental set-up had been characterized and removed. In addition, different clusters were clarified so as to compute and analyze the angular autocorrelation of different clusters more effectively.},
doi = {10.1142/s0217984920500189},
journal = {Modern Physics Letters B},
number = 02,
volume = 34,
place = {United States},
year = {2019},
month = {12}
}

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Works referenced in this record:

An assessment of the resolution limitation due to radiation-damage in X-ray diffraction microscopy
journal, March 2009

  • Howells, M. R.; Beetz, T.; Chapman, H. N.
  • Journal of Electron Spectroscopy and Related Phenomena, Vol. 170, Issue 1-3
  • DOI: 10.1016/j.elspec.2008.10.008

Single-particle structure determination by correlations of snapshot X-ray diffraction patterns
journal, January 2012

  • Starodub, D.; Aquila, A.; Bajt, S.
  • Nature Communications, Vol. 3, Issue 1
  • DOI: 10.1038/ncomms2288

Structure determination through correlated fluctuations in x-ray scattering
journal, November 2012


Observation of correlated X-ray scattering at atomic resolution
journal, July 2014

  • Mendez, Derek; Lane, Thomas J.; Sung, Jongmin
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 369, Issue 1647
  • DOI: 10.1098/rstb.2013.0315

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
journal, May 2012


Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight
journal, June 2012

  • Loh, N. D.; Hampton, C. Y.; Martin, A. V.
  • Nature, Vol. 486, Issue 7404
  • DOI: 10.1038/nature11222

First lasing and operation of an ångstrom-wavelength free-electron laser
journal, August 2010


A compact X-ray free-electron laser emitting in the sub-ångström region
journal, June 2012


Coherent X-ray scattering and lensless imaging at the European XFEL Facility
journal, October 2007

  • Vartanyants, I. A.; Robinson, I. K.; McNulty, I.
  • Journal of Synchrotron Radiation, Vol. 14, Issue 6
  • DOI: 10.1107/S0909049507037600

Progress Toward an Ultimate Storage Ring Light Source
journal, March 2013


AMO science at the FLASH and European XFEL free-electron laser facilities
journal, August 2013

  • Feldhaus, J.; Krikunova, M.; Meyer, M.
  • Journal of Physics B: Atomic, Molecular and Optical Physics, Vol. 46, Issue 16
  • DOI: 10.1088/0953-4075/46/16/164002

Determination of Macromolecular Structure in Solution by Spatial Correlation of Scattering Fluctuations
journal, September 1977


Iterative phasing for fluctuation X-ray scattering
journal, August 2015

  • Donatelli, Jeffrey J.; Zwart, Peter H.; Sethian, James A.
  • Proceedings of the National Academy of Sciences, Vol. 112, Issue 33
  • DOI: 10.1073/pnas.1513738112

Fluctuation x-ray scattering from biological particles in frozen solution by using synchrotron radiation.
journal, June 1981

  • Kam, Z.; Koch, M. H.; Bordas, J.
  • Proceedings of the National Academy of Sciences, Vol. 78, Issue 6
  • DOI: 10.1073/pnas.78.6.3559