skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

This content will become publicly available on February 21, 2021

Title: Modeling the dynamics of phospholipids in the fluid phase of liposomes

Abstract

We present the derivation of a new model to describe neutron spin echo spectroscopy and quasi-elastic neutron scattering data on liposomes.

Authors:
ORCiD logo [1]; ORCiD logo [2]
  1. Department of Chemistry, Louisiana State University, Baton Rouge, USA
  2. Department of Chemistry, Louisiana State University, Baton Rouge, USA, Department of Physics & Astronomy
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1604241
Grant/Contract Number:  
EPSCoR Grant No. DE-SC0012432
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Soft Matter
Additional Journal Information:
Journal Name: Soft Matter Journal Volume: 16 Journal Issue: 13; Journal ID: ISSN 1744-683X
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Gupta, Sudipta, and Schneider, Gerald J. Modeling the dynamics of phospholipids in the fluid phase of liposomes. United Kingdom: N. p., 2020. Web. doi:10.1039/C9SM02111F.
Gupta, Sudipta, & Schneider, Gerald J. Modeling the dynamics of phospholipids in the fluid phase of liposomes. United Kingdom. doi:10.1039/C9SM02111F.
Gupta, Sudipta, and Schneider, Gerald J. Wed . "Modeling the dynamics of phospholipids in the fluid phase of liposomes". United Kingdom. doi:10.1039/C9SM02111F.
@article{osti_1604241,
title = {Modeling the dynamics of phospholipids in the fluid phase of liposomes},
author = {Gupta, Sudipta and Schneider, Gerald J.},
abstractNote = {We present the derivation of a new model to describe neutron spin echo spectroscopy and quasi-elastic neutron scattering data on liposomes.},
doi = {10.1039/C9SM02111F},
journal = {Soft Matter},
number = 13,
volume = 16,
place = {United Kingdom},
year = {2020},
month = {4}
}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on February 21, 2021
Publisher's Version of Record

Save / Share:

Works referenced in this record:

Mechanical Properties of Nanoscopic Lipid Domains
journal, October 2015

  • Nickels, Jonathan D.; Cheng, Xiaolin; Mostofian, Barmak
  • Journal of the American Chemical Society, Vol. 137, Issue 50
  • DOI: 10.1021/jacs.5b08894

Protein Entrapment in Polymeric Mesh: Diffusion in Crowded Environment with Fast Process on Short Scales
journal, February 2016


Anomalous Diffusion of Phospholipids and Cholesterols in a Lipid Bilayer and its Origins
journal, October 2012


Spherical harmonics analysis of surface density fluctuations of spherical ionic SDS and nonionic C12E8 micelles: A molecular dynamics study
journal, July 2017

  • Yoshii, Noriyuki; Nimura, Yuki; Fujimoto, Kazushi
  • The Journal of Chemical Physics, Vol. 147, Issue 3
  • DOI: 10.1063/1.4994698

A molecular dynamics study of the breathing and deforming modes of the spherical ionic SDS and nonionic C12E8 micelles
journal, January 2016

  • Wang, Lin; Fujimoto, Kazushi; Yoshii, Noriyuki
  • The Journal of Chemical Physics, Vol. 144, Issue 3
  • DOI: 10.1063/1.4940031

Dynamics of Phospholipid Membranes beyond Thermal Undulations
journal, May 2018

  • Gupta, Sudipta; De Mel, Judith U.; Perera, Rasangi M.
  • The Journal of Physical Chemistry Letters, Vol. 9, Issue 11
  • DOI: 10.1021/acs.jpclett.8b01008

Dynamical fluctuations of droplet microemulsions and vesicles
journal, November 1987


Transbilayer Pores Induced by Thickness Fluctuations
journal, April 2006

  • Movileanu, Liviu; Popescu, Dumitru; Ion, Stelian
  • Bulletin of Mathematical Biology, Vol. 68, Issue 6
  • DOI: 10.1007/s11538-006-9069-9

Use of Fluorescent Probes: Their Effect on Cell Biology and Limitations
journal, October 2012

  • Jensen, Ellen C.
  • The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, Vol. 295, Issue 12
  • DOI: 10.1002/ar.22602

Reply to “Comment on ‘Dynamics of Phospholipid Membranes beyond Thermal Undulation’”
journal, May 2019

  • Gupta, Sudipta; De Mel, Judith U.; Schneider, Gerald J.
  • The Journal of Physical Chemistry B, Vol. 123, Issue 26
  • DOI: 10.1021/acs.jpcb.9b04739

Equivalent Pathways in Melting and Gelation of Well-Defined Biopolymer Networks
journal, December 2014

  • Cingil, Hande E.; Rombouts, Wolf H.; van der Gucht, Jasper
  • Biomacromolecules, Vol. 16, Issue 1
  • DOI: 10.1021/bm5015014

Probing Elastic and Viscous Properties of Phospholipid Bilayers Using Neutron Spin Echo Spectroscopy
journal, September 2017

  • Nagao, Michihiro; Kelley, Elizabeth G.; Ashkar, Rana
  • The Journal of Physical Chemistry Letters, Vol. 8, Issue 19
  • DOI: 10.1021/acs.jpclett.7b01830

Effect of benzocaine and propranolol on phospholipid-based bilayers
journal, January 2017

  • Mangiapia, G.; Gvaramia, M.; Kuhrts, L.
  • Physical Chemistry Chemical Physics, Vol. 19, Issue 47
  • DOI: 10.1039/C7CP06077G

Structure of lipid bilayers
journal, November 2000

  • Nagle, John F.; Tristram-Nagle, Stephanie
  • Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, Vol. 1469, Issue 3
  • DOI: 10.1016/S0304-4157(00)00016-2

Spatial organization of the flow of genetic information in bacteria
journal, June 2010

  • Montero Llopis, Paula; Jackson, Audrey F.; Sliusarenko, Oleksii
  • Nature, Vol. 466, Issue 7302
  • DOI: 10.1038/nature09152

ADAPTORS FOR CLATHRIN COATS: Structure and Function
journal, November 2004


Spatial Structure and Composition of Polysaccharide−Protein Complexes from Small Angle Neutron Scattering
journal, June 2009

  • Schmidt, I.; Cousin, F.; Huchon, C.
  • Biomacromolecules, Vol. 10, Issue 6
  • DOI: 10.1021/bm801147j

Structure of Artificial Cytoskeleton Containing Liposomes in Aqueous Solution Studied by Static and Dynamic Light Scattering
journal, May 2002

  • Stauch, Oliver; Schubert, Rolf; Savin, Gabriela
  • Biomacromolecules, Vol. 3, Issue 3
  • DOI: 10.1021/bm0200074

Subdiffusion and lateral diffusion coefficient of lipid atoms and molecules in phospholipid bilayers
journal, January 2009


Neutron spin–echo investigations of membrane undulations in complex fluids involving amphiphiles
journal, September 1999


Fluctuation dynamics of bilayer vesicles with intermonolayer sliding: Experiment and theory
journal, January 2015


Energetics of fluctuation in lipid bilayer thickness
journal, March 1984


Softening of phospholipid membranes by the adhesion of silica nanoparticles – as seen by neutron spin-echo (NSE)
journal, January 2014

  • Hoffmann, Ingo; Michel, Raphael; Sharp, Melissa
  • Nanoscale, Vol. 6, Issue 12
  • DOI: 10.1039/C4NR00774C

Quasielastic Neutron Scattering Study on the Dynamics of Poly(alkylene oxide)s
journal, May 2012

  • Gerstl, C.; Schneider, G. J.; Fuxman, A.
  • Macromolecules, Vol. 45, Issue 10
  • DOI: 10.1021/ma3003399

Tuning Membrane Thickness Fluctuations in Model Lipid Bilayers
journal, July 2015


Effect of adding nanometre-sized heterogeneities on the structural dynamics and the excess wing of a molecular glass former
journal, October 2016

  • Gupta, S.; Fischer, J. K. H.; Lunkenheimer, P.
  • Scientific Reports, Vol. 6, Issue 1
  • DOI: 10.1038/srep35034

Incorporation of aspirin modulates the dynamical and phase behavior of the phospholipid membrane
journal, January 2017

  • Sharma, V. K.; Mamontov, E.; Ohl, M.
  • Physical Chemistry Chemical Physics, Vol. 19, Issue 3
  • DOI: 10.1039/C6CP06202D

Cellular Uptake of Elastic Nanoparticles
journal, August 2011


Achiral symmetry breaking and positive Gaussian modulus lead to scalloped colloidal membranes
journal, April 2017

  • Gibaud, Thomas; Kaplan, C. Nadir; Sharma, Prerna
  • Proceedings of the National Academy of Sciences, Vol. 114, Issue 17
  • DOI: 10.1073/pnas.1617043114

Dynamics of bicontinuous microemulsion phases with and without amphiphilic block-copolymers
journal, November 2001

  • Mihailescu, M.; Monkenbusch, M.; Endo, H.
  • The Journal of Chemical Physics, Vol. 115, Issue 20
  • DOI: 10.1063/1.1413509

Dynamics of small unilamellar vesicles
journal, March 2018

  • Hoffmann, Ingo; Hoffmann, Claudia; Farago, Bela
  • The Journal of Chemical Physics, Vol. 148, Issue 10
  • DOI: 10.1063/1.5009424

Multi-component modeling of quasielastic neutron scattering from phospholipid membranes
journal, May 2014

  • Wanderlingh, U.; D’Angelo, G.; Branca, C.
  • The Journal of Chemical Physics, Vol. 140, Issue 17
  • DOI: 10.1063/1.4872167

Differential Dynamic and Structural Behavior of Lipid-Cholesterol Domains in Model Membranes
journal, June 2012


Fluctuation dynamics of spherical vesicles: Frustration of regular bulk dissipation into subdiffusive relaxation
journal, September 2009

  • Arriaga, Laura R.; López-Montero, Iván; Orts-Gil, Guillermo
  • Physical Review E, Vol. 80, Issue 3
  • DOI: 10.1103/PhysRevE.80.031908

Lipid Bilayers and Membrane Dynamics: Insight into Thickness Fluctuations
journal, July 2012


Dynamics of liposomes in the fluid phase
journal, August 2019

  • Gupta, Sudipta; De Mel, Judith U.; Schneider, Gerald J.
  • Current Opinion in Colloid & Interface Science, Vol. 42
  • DOI: 10.1016/j.cocis.2019.05.003

Thermal fluctuations of large quasi-spherical bimolecular phospholipid vesicles
journal, January 1984


A Molecular View of Melting in Anhydrous Phospholipidic Membranes
journal, January 2007


Construction and Structural Analysis of Tethered Lipid Bilayer Containing Photosynthetic Antenna Proteins for Functional Analysis
journal, July 2011

  • Sumino, Ayumi; Dewa, Takehisa; Takeuchi, Toshikazu
  • Biomacromolecules, Vol. 12, Issue 7
  • DOI: 10.1021/bm200585y

Lipid Rafts As a Membrane-Organizing Principle
journal, December 2009


Ergodic and nonergodic processes coexist in the plasma membrane as observed by single-molecule tracking
journal, April 2011

  • Weigel, A. V.; Simon, B.; Tamkun, M. M.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 16
  • DOI: 10.1073/pnas.1016325108

Undulations and Dynamic Structure Factor of Membranes
journal, December 1996


Synthesis and Characterization of Well-Defined PEGylated Polypeptoids as Protein-Resistant Polymers
journal, February 2017


Multiscale mode dynamics of a tethered membrane
journal, June 2007


Functional rafts in cell membranes
journal, June 1997

  • Simons, Kai; Ikonen, Elina
  • Nature, Vol. 387, Issue 6633
  • DOI: 10.1038/42408

Phospholipid bilayers are viscoelastic
journal, October 2010

  • Harland, C. W.; Bradley, M. J.; Parthasarathy, R.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue 45
  • DOI: 10.1073/pnas.1010700107

Bending stiffness of biological membranes: What can be measured by neutron spin echo?
journal, July 2013

  • Mell, Michael; Moleiro, Lara H.; Hertle, Yvonne
  • The European Physical Journal E, Vol. 36, Issue 7
  • DOI: 10.1140/epje/i2013-13075-2

Dynamics of an asymmetric bilayer lipid membrane in a viscous solvent
journal, July 2015


Anomalous chain diffusion in unentangled model polymer nanocomposites
journal, January 2013

  • Schneider, Gerald J.; Nusser, Klaus; Neueder, Susanne
  • Soft Matter, Vol. 9, Issue 16
  • DOI: 10.1039/c3sm27886g

Quantification of Multivalent Interactions by Tracking Single Biological Nanoparticle Mobility on a Lipid Membrane
journal, June 2016


How gene order is influenced by the biophysics of transcription regulation
journal, August 2007

  • Kolesov, G.; Wunderlich, Z.; Laikova, O. N.
  • Proceedings of the National Academy of Sciences, Vol. 104, Issue 35
  • DOI: 10.1073/pnas.0700672104

Non-Gaussian Fluctuations Resulting from Power-Law Trapping in a Lipid Bilayer
journal, October 2011


Liposomal drug delivery systems: From concept to clinical applications
journal, January 2013


Interpreting Membrane Scattering Experiments at the Mesoscale: The Contribution of Dissipation within the Bilayer
journal, March 2010