Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening
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text
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January 2018 |
Protein transport into peroxisomes: Knowns and unknowns
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journal
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August 2017 |
Serial femtosecond crystallography: A revolution in structural biology
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journal
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July 2016 |
CBS domains: Ligand binding sites and conformational variability
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journal
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December 2013 |
Accurate determination of segmented X-ray detector geometry
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journal
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January 2015 |
IMP Dehydrogenase: Structure, Mechanism, and Inhibition
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journal
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July 2009 |
Accurate determination of segmented X-ray detector geometry
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text
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January 2015 |
Characteristics and Crystal Structure of Bacterial Inosine-5‘-monophosphate Dehydrogenase † , ‡
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journal
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April 1999 |
An anti-settling sample delivery instrument for serial femtosecond crystallography
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journal
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July 2012 |
Amplification of the inosinate dehydrogenase gene in Trypanosoma brucei gambiense due to an increase in chromosome copy number.
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journal
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November 1994 |
Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening
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text
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January 2018 |
Serial crystallography at synchrotrons and X-ray lasers
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journal
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February 2017 |
In vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins
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journal
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July 2015 |
Kinetic Mechanism of Human Inosine 5‘-Monophosphate Dehydrogenase Type II: Random Addition of Substrates and Ordered Release of Products †
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journal
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July 1997 |
Two Classes of Bacterial IMPDHs according to Their Quaternary Structures and Catalytic Properties
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journal
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February 2015 |
Phaser.MRage: automated molecular replacement.
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text
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January 2013 |
De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure
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September 2016 |
Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes
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July 2012 |
Radiation damage in protein crystallography at X-ray free-electron lasers
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journal
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January 2019 |
Serial femtosecond crystallography: A revolution in structural biology
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journal
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July 2016 |
Femtosecond X-ray protein nanocrystallography
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journal
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February 2011 |
Injector for scattering measurements on fully solvated biospecies
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March 2012 |
A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity
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journal
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March 2019 |
Radiation damage in protein crystallography at X-ray free-electron lasers
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journal
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December 2017 |
A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases
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journal
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June 2017 |
Inosine monophosphate dehydrogenase as a target for antiviral, anticancer, antimicrobial and immunosuppressive therapeutics
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journal
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January 2010 |
Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation
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journal
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August 2015 |
XGANDALF – extended gradient descent algorithm for lattice finding
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text
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January 2019 |
Serial femtosecond crystallography: the first five years
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journal
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February 2015 |
The molecular organization of cypovirus polyhedra
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journal
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March 2007 |
Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes
|
journal
|
July 2012 |
In vivo protein crystallization opens new routes in structural biology
|
journal
|
January 2012 |
First-in-class allosteric inhibitors of bacterial IMPDHs
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journal
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April 2019 |
IMP Dehydrogenase: Structure, Mechanism, and Inhibition
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journal
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July 2009 |
A Diffraction-Quality Protein Crystal Processed as an Autophagic Cargo
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journal
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April 2015 |
XGANDALF – extended gradient descent algorithm for lattice finding
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text
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January 2019 |
High-throughput decoding of antitrypanosomal drug efficacy and resistance
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journal
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January 2012 |
Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase
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journal
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February 2013 |
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
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November 2004 |
Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation
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journal
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August 2015 |
Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
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September 2002 |
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease
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text
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January 2007 |
A pipeline for structure determination of in vivo -grown crystals using in cellulo diffraction
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journal
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March 2016 |
Sleeping Sickness in the ‘Omics Era
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journal
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April 2018 |
Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases
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journal
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November 2015 |
Characterization of the novel Trypanosoma brucei inosine 5′-monophosphate dehydrogenase
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journal
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February 2013 |
Two Classes of Bacterial IMPDHs according to Their Quaternary Structures and Catalytic Properties
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journal
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February 2015 |
One Fold with Many Functions: The Evolutionary Relationships between TIM Barrel Families Based on their Sequences, Structures and Functions
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journal
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August 2002 |
Consequences of IMP Dehydrogenase Inhibition, and its Relationship to Cancer and Apoptosis
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journal
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July 1999 |
Phaser.MRage : automated molecular replacement
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journal
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October 2013 |
Radiation damage in protein crystallography at X-ray free-electron lasers
|
journal
|
December 2017 |
Physiological concentrations of purines and pyrimidines
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journal
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January 1994 |
A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases
|
journal
|
June 2017 |
Protein transport into peroxisomes: Knowns and unknowns
|
journal
|
August 2017 |
Protein crystallization in vivo
|
text
|
January 2005 |
Protein crystallization in living cells
|
journal
|
June 2018 |
CBS domains: Ligand binding sites and conformational variability
|
journal
|
December 2013 |
Physiological concentrations of purines and pyrimidines
|
journal
|
January 1994 |
Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening
|
text
|
January 2018 |
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans
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journal
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October 2012 |
An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1
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journal
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November 2015 |
Real-time investigation of dynamic protein crystallization in living cells
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journal
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July 2015 |
MgATP Regulates Allostery and Fiber Formation in IMPDHs
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journal
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June 2013 |
Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening
|
journal
|
November 2018 |
Sleeping Sickness in the ‘Omics Era
|
journal
|
April 2018 |
A Diffraction-Quality Protein Crystal Processed as an Autophagic Cargo
|
journal
|
April 2015 |
Protein crystallization in living cells
|
journal
|
June 2018 |
Coot model-building tools for molecular graphics
|
journal
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November 2004 |
Towards automated crystallographic structure refinement with phenix.refine
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journal
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March 2012 |
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease
|
text
|
January 2007 |
High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
|
journal
|
May 2012 |
In vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins
|
journal
|
July 2015 |
First-in-class allosteric inhibitors of bacterial IMPDHs
|
journal
|
April 2019 |
An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1
|
journal
|
November 2015 |
Protein crystallization in vivo
|
journal
|
April 2006 |
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease
|
journal
|
December 2007 |
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans
|
journal
|
October 2012 |
Real-time investigation of dynamic protein crystallization in living cells
|
journal
|
July 2015 |
Kinetic Mechanism of Human Inosine 5‘-Monophosphate Dehydrogenase Type II: Random Addition of Substrates and Ordered Release of Products †
|
journal
|
July 1997 |
The Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS)
|
journal
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March 2010 |
MgATP Regulates Allostery and Fiber Formation in IMPDHs
|
journal
|
June 2013 |
Accurate determination of segmented X-ray detector geometry
|
journal
|
January 2015 |
Serial femtosecond crystallography: the first five years
|
journal
|
February 2015 |
Phaser.MRage : automated molecular replacement
|
journal
|
October 2013 |
Inosine 5′-monophosphate dehydrogenase inhibitors as antimicrobial agents: recent progress and future perspectives
|
journal
|
August 2015 |
Femtosecond X-ray protein nanocrystallography
|
journal
|
February 2011 |
XGANDALF – extended gradient descent algorithm for lattice finding
|
journal
|
August 2019 |
Coot model-building tools for molecular graphics
|
journal
|
November 2004 |
Firefly luciferase is targeted to peroxisomes in mammalian cells.
|
journal
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May 1987 |
Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams
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journal
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February 2015 |
Increased riboflavin production by manipulation of inosine 5′-monophosphate dehydrogenase in Ashbya gossypii
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journal
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July 2015 |
CrystFEL : a software suite for snapshot serial crystallography
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journal
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March 2012 |
First lasing and operation of an ångstrom-wavelength free-electron laser
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journal
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August 2010 |
A pipeline for structure determination of in vivo -grown crystals using in cellulo diffraction
|
journal
|
March 2016 |
Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams
|
journal
|
February 2015 |
The structure of a domain common to archaebacteria and the homocystinuria disease protein
|
journal
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January 1997 |
Inosine monophosphate dehydrogenase as a target for antiviral, anticancer, antimicrobial and immunosuppressive therapeutics
|
journal
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January 2010 |
Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser
|
journal
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November 2012 |
Firefly luciferase is targeted to peroxisomes in mammalian cells.
|
journal
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May 1987 |
High-throughput decoding of antitrypanosomal drug efficacy and resistance
|
journal
|
January 2012 |
Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase
|
journal
|
February 2013 |
Increased riboflavin production by manipulation of inosine 5′-monophosphate dehydrogenase in Ashbya gossypii
|
journal
|
July 2015 |
In vivo protein crystallization opens new routes in structural biology
|
journal
|
January 2012 |
First lasing and operation of an ångstrom-wavelength free-electron laser
|
journal
|
August 2010 |
Cheetah : software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data
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journal
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May 2014 |
Protein crystallization in vivo
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journal
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April 2006 |