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Title: Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains

Journal Article · · Current Research in Structural Biology

Not Available

Sponsoring Organization:
USDOE
OSTI ID:
1599965
Journal Information:
Current Research in Structural Biology, Journal Name: Current Research in Structural Biology Journal Issue: C Vol. 2; ISSN 2665-928X
Publisher:
ElsevierCopyright Statement
Country of Publication:
Netherlands
Language:
English

References (67)

Structural Elucidation of the Bispecificity of A Domains as a Basis for Activating Non-natural Amino Acids journal June 2015
MolProbity: More and better reference data for improved all-atom structure validation: PROTEIN SCIENCE.ORG journal November 2017
Structural Biology of Nonribosomal Peptide Synthetases book February 2016
A Family of LIC Vectors for High-Throughput Cloning and Purification of Proteins book January 2009
Cleavable C-terminal His-tag vectors for structure determination journal March 2010
The P-loop — a common motif in ATP- and GTP-binding proteins journal November 1990
Structural Basis for the Cyclization of the Lipopeptide Antibiotic Surfactin by the Thioesterase Domain SrfTE journal March 2002
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases journal August 1999
Structural and functional aspects of the nonribosomal peptide synthetase condensation domain superfamily: discovery, dissection and diversity journal November 2017
Magnesium dependence of the measured equilibrium constants of aminoacyl-tRNA synthetases journal December 2007
Structural insight into the necessary conformational changes of modular nonribosomal peptide synthetases journal December 2016
Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases journal March 2016
The Thioesterase Domain of the Fengycin Biosynthesis Cluster: A Structural Base for the Macrocyclization of a Non-ribosomal Lipopeptide journal June 2006
Inference of Macromolecular Assemblies from Crystalline State journal September 2007
Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases journal September 2013
Mapping of the Communication-Mediating Interface in Nonribosomal Peptide Synthetases Using a Genetically Encoded Photocrosslinker Supports an Upside-Down Helix-Hand Motif journal October 2016
An Unusual Allosteric Mobility of the C-Terminal Helix of a High-Affinity αL Integrin I Domain Variant Bound to ICAM-5 journal August 2008
A combined approach to improving large-scale production of tobacco etch virus protease journal September 2007
Structural aspects of non-ribosomal peptide biosynthesis journal December 2004
Adenylate-forming enzymes journal December 2009
Nonribosomal peptide synthetases: structures and dynamics journal April 2010
Structural and Functional Insights into a Peptide Bond-Forming Bidomain from a Nonribosomal Peptide Synthetase journal July 2007
X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture journal May 2017
Thioesterase-Mediated Synthesis of Teixobactin Analogues: Mechanism and Substrate Specificity journal January 2018
Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases journal June 2016
The 1.75 Å Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5‘-propylphosphate and Coenzyme A journal March 2003
Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains journal April 2012
Assembly-Line Enzymology for Polyketide and Nonribosomal Peptide Antibiotics:  Logic, Machinery, and Mechanisms journal August 2006
Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis journal November 1997
Production of selenomethionine-labeled proteins in two-liter plastic bottles for structure determination journal March 2004
A new antibiotic kills pathogens without detectable resistance journal January 2015
X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis journal February 2015
Structures of two distinct conformations of holo-non-ribosomal peptide synthetases journal January 2016
Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase journal January 2016
The structural biology of biosynthetic megaenzymes journal August 2015
A chemocentric view of the natural product inventory journal August 2015
Structural basis of nonribosomal peptide macrocyclization in fungi journal October 2016
The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase journal July 2019
Diversity of nature's assembly lines – recent discoveries in non-ribosomal peptide synthesis journal January 2017
Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus journal January 2018
Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens journal January 2017
Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides journal January 2006
Structural elements of an NRPS cyclization domain and its intermodule docking domain journal October 2016
Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases journal September 2002
Structure of chloramphenicol acetyltransferase at 1.75-A resolution. journal June 1988
The Crystal Structure of the Adenylation Enzyme VinN Reveals a Unique β-Amino Acid Recognition Mechanism journal November 2014
Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture journal September 2016
Crystal Structure of DltA: IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE ADENYLATION DOMAINS journal September 2008
Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S journal July 1997
Ligation-independent cloning of PCR products (LIC-PCR) journal January 1990
Substructure solution with SHELXD journal September 2002
Coot model-building tools for molecular graphics journal November 2004
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions journal November 2004
HKL -3000: the integration of data reduction and structure solution – from diffraction images to an initial model in minutes journal July 2006
Molecular replacement with MOLREP journal December 2009
Overview of the CCP 4 suite and current developments journal March 2011
Towards automated crystallographic structure refinement with phenix.refine journal March 2012
The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results journal December 2005
A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division: Control of cell wall-remodelling enzymes journal July 2012
Structural Basis of a Phototropin Light Switch journal September 2003
Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase journal August 2008
Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis journal August 2016
The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains. journal January 1997
Structural Basis of Integrin Regulation and Signaling journal April 2007
Express Primer Tool for High-Throughput Gene Cloning and Expression journal December 2002
Alpha Beta-Hydrolase Fold Enzymes Structures, Functions and Mechanisms journal September 2000
Nonribosomal Peptides from Marine Microbes and Their Antimicrobial and Anticancer Potential journal November 2017