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Title: Establishment of computational biology in Greece and Cyprus: Past, present, and future

Abstract

We review the establishment of computational biology in Greece and Cyprus from its inception to date and issue recommendations for future development. We compare output to other countries of similar geography, economy, and size—based on publication counts recorded in the literature—and predict future growth based on those counts as well as national priority areas. Our analysis may be pertinent to wider national or regional communities with challenges and opportunities emerging from the rapid expansion of the field and related industries. Our recommendations suggest a 2-fold growth margin for the 2 countries, as a realistic expectation for further expansion of the field and the development of a credible roadmap of national priorities, both in terms of research and infrastructure funding.

Authors:
ORCiD logo [1];  [2];  [2]; ORCiD logo [3]; ORCiD logo [4]; ORCiD logo [2];  [2]; ORCiD logo [5]; ORCiD logo [6];  [2];  [7]; ORCiD logo [8];  [2];  [9]; ORCiD logo [10]; ORCiD logo [1];  [11]
  1. Centre for Research & Technology Hellas, Thessalonica (Greece)
  2. Aristotle Univ. of Thessaloniki, Thessalonica (Greece)
  3. Univ. of Oxford (United Kingdom)
  4. Univ. of Crete, Heraklion (Greece)
  5. USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
  6. Hellenic Centre for Marine Research, Heraklion (Greece)
  7. Foundation for Research and Technology Hellas, Heraklion (Greece)
  8. Univ. of Patras (Greece)
  9. National Centre for Scientific Research Demokritos, Athens (Greece)
  10. Univ. of Cyprus, Nicosia (Cyprus)
  11. Univ. of Virginia, Charlottesville, VA (United States)
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1599826
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Accepted Manuscript
Journal Name:
PLoS Computational Biology (Online)
Additional Journal Information:
Journal Name: PLoS Computational Biology (Online); Journal Volume: 15; Journal Issue: 12; Journal ID: ISSN 1553-7358
Publisher:
Public Library of Science
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; cyprus; Greece; bioinformatics; computational biology; Europe; molecular biology; graduates; government laboratories

Citation Formats

Chasapi, Anastasia, Aivaliotis, Michalis, Angelis, Lefteris, Chanalaris, Anastasios, Iliopoulos, Ioannis, Kappas, Ilias, Karapiperis, Christos, Kyrpides, Nikos C., Pafilis, Evangelos, Panteris, Eleftherios, Topalis, Pantelis, Tsiamis, George, Vizirianakis, Ioannis S., Vlassi, Metaxia, Promponas, Vasilis J., Ouzounis, Christos A., and Papin, Jason A. Establishment of computational biology in Greece and Cyprus: Past, present, and future. United States: N. p., 2019. Web. doi:10.1371/journal.pcbi.1007532.
Chasapi, Anastasia, Aivaliotis, Michalis, Angelis, Lefteris, Chanalaris, Anastasios, Iliopoulos, Ioannis, Kappas, Ilias, Karapiperis, Christos, Kyrpides, Nikos C., Pafilis, Evangelos, Panteris, Eleftherios, Topalis, Pantelis, Tsiamis, George, Vizirianakis, Ioannis S., Vlassi, Metaxia, Promponas, Vasilis J., Ouzounis, Christos A., & Papin, Jason A. Establishment of computational biology in Greece and Cyprus: Past, present, and future. United States. doi:10.1371/journal.pcbi.1007532.
Chasapi, Anastasia, Aivaliotis, Michalis, Angelis, Lefteris, Chanalaris, Anastasios, Iliopoulos, Ioannis, Kappas, Ilias, Karapiperis, Christos, Kyrpides, Nikos C., Pafilis, Evangelos, Panteris, Eleftherios, Topalis, Pantelis, Tsiamis, George, Vizirianakis, Ioannis S., Vlassi, Metaxia, Promponas, Vasilis J., Ouzounis, Christos A., and Papin, Jason A. Thu . "Establishment of computational biology in Greece and Cyprus: Past, present, and future". United States. doi:10.1371/journal.pcbi.1007532. https://www.osti.gov/servlets/purl/1599826.
@article{osti_1599826,
title = {Establishment of computational biology in Greece and Cyprus: Past, present, and future},
author = {Chasapi, Anastasia and Aivaliotis, Michalis and Angelis, Lefteris and Chanalaris, Anastasios and Iliopoulos, Ioannis and Kappas, Ilias and Karapiperis, Christos and Kyrpides, Nikos C. and Pafilis, Evangelos and Panteris, Eleftherios and Topalis, Pantelis and Tsiamis, George and Vizirianakis, Ioannis S. and Vlassi, Metaxia and Promponas, Vasilis J. and Ouzounis, Christos A. and Papin, Jason A.},
abstractNote = {We review the establishment of computational biology in Greece and Cyprus from its inception to date and issue recommendations for future development. We compare output to other countries of similar geography, economy, and size—based on publication counts recorded in the literature—and predict future growth based on those counts as well as national priority areas. Our analysis may be pertinent to wider national or regional communities with challenges and opportunities emerging from the rapid expansion of the field and related industries. Our recommendations suggest a 2-fold growth margin for the 2 countries, as a realistic expectation for further expansion of the field and the development of a credible roadmap of national priorities, both in terms of research and infrastructure funding.},
doi = {10.1371/journal.pcbi.1007532},
journal = {PLoS Computational Biology (Online)},
number = 12,
volume = 15,
place = {United States},
year = {2019},
month = {12}
}

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Works referenced in this record:

Bioinformatics in Jordan: Status, challenges, and future directions
journal, September 2019


Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
journal, April 2019


Bioinformatics and Computational Biology in Poland
journal, May 2013


Early bioinformatics: the birth of a discipline--a personal view
journal, November 2003


Brain Radiation Information Data Exchange (BRIDE): integration of experimental data from low-dose ionising radiation research for pathway discovery
journal, May 2016

  • Karapiperis, Christos; Kempf, Stefan J.; Quintens, Roel
  • BMC Bioinformatics, Vol. 17, Issue 1
  • DOI: 10.1186/s12859-016-1068-8

The New Economy: Reality and Policy
journal, September 2001


Designing and running an advanced Bioinformatics and genome analyses course in Tunisia
journal, January 2019


Two or three myths about bioinformatics
journal, March 2000


The origins of bioinformatics
journal, December 2000


Classification schemes for protein structure and function
journal, July 2003

  • Ouzounis, Christos A.; Coulson, Richard M. R.; Enright, Anton J.
  • Nature Reviews Genetics, Vol. 4, Issue 7
  • DOI: 10.1038/nrg1113

Perspectives on Translational Genomics and Public Health in India
journal, December 2015

  • Chakrabarty, Sanjiban; Kabekkodu, Shama Prasada; Brand, Angela
  • Public Health Genomics, Vol. 19, Issue 2
  • DOI: 10.1159/000442518

Core services: Reward bioinformaticians
journal, April 2015


Outlook on Thailand's Genomics and Computational Biology Research and Development
journal, July 2008

  • Tongsima, Wannipha; Tongsima, Sissades; Palittapongarnpim, Prasit
  • PLoS Computational Biology, Vol. 4, Issue 7
  • DOI: 10.1371/journal.pcbi.1000115

Bioinformatics in Malaysia: Hope, Initiative, Effort, Reality, and Challenges
journal, August 2009


Meeting Report: the Seventh Conference of the Hellenic Society for Computational Biology and Bioinformatics
journal, March 2013

  • Hamodrakas, Stavros J.; Iliopoulos, Ioannis; Ouzounis, Christos A.
  • Computational and Structural Biotechnology Journal, Vol. 6, Issue 7
  • DOI: 10.5936/csbj.201303006

Computational Biology in Colombia
journal, October 2009

  • Restrepo, Silvia; Pinzón, Andrés; Rodríguez-R, Luis Miguel
  • PLoS Computational Biology, Vol. 5, Issue 10
  • DOI: 10.1371/journal.pcbi.1000535

Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
journal, October 2002

  • Zdobnov, Evgeny M.; von Mering, Christian; Letunic, Ivica
  • Science, Vol. 298, Issue 5591
  • DOI: 10.1126/science.1077061

Computational Biology in Argentina
journal, January 2007


Development of Genomic Sciences in Mexico: A Good Start and a Long Way to Go
journal, January 2007


Bioinformatics in China: A Personal Perspective
journal, April 2008


The Development of Computational Biology in Pakistan: Still a Long Way to Go
journal, June 2011


Genomics Politics through Space and Time: The Case of Bioinformatics in Brazil
journal, January 2016


Genome-Scale Computational Biology and Bioinformatics in Australia
journal, August 2008


Rise and Demise of Bioinformatics? Promise and Progress
journal, April 2012


Computational Biology in Brazil
journal, January 2007


Bioinformatic challenges for the next decade(s)
journal, February 2006

  • Eisenberg, David; Marcotte, Edward; McLachlan, Andrew D.
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 361, Issue 1467
  • DOI: 10.1098/rstb.2005.1797

Strategies and opportunities for promoting bioinformatics in Zimbabwe
journal, November 2018


Evaluation of annotation strategies using an entire genome sequence
journal, April 2003


Generations of interdisciplinarity in bioinformatics
journal, April 2016


H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa
journal, December 2015

  • Baichoo, Shakuntala; Botha, Gerrit; Jaufeerally-Fakim, Yasmina
  • Standards in Genomic Sciences, Vol. 10, Issue 1
  • DOI: 10.1186/s40793-015-0111-0

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
journal, November 2014

  • Neafsey, Daniel E.; Waterhouse, Robert M.; Abai, Mohammad R.
  • Science, Vol. 347, Issue 6217
  • DOI: 10.1126/science.1258522

Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains
journal, August 2014


Computational Biology in Costa Rica: The Role of a Small Country in the Global Context of Bioinformatics
journal, March 2008


Brief Overview of Bioinformatics Activities in Singapore
journal, September 2009


Cross-national Differences in the Expansion of Science, 1970-1990
journal, September 2004


Toward unrestricted use of public genomic data
journal, January 2019

  • Amann, Rudolf I.; Baichoo, Shakuntala; Blencowe, Benjamin J.
  • Science, Vol. 363, Issue 6425
  • DOI: 10.1126/science.aaw1280

Bioinformatics and the theoretical foundations of molecular biology
journal, March 2002


Computational Biology in Cuba: An Opportunity to Promote Science in a Developing Country
journal, January 2007


Computational Biology and Bioinformatics in Nigeria
journal, April 2014


Bioinformatics in Africa: The Rise of Ghana?
journal, September 2015


The Genome Sequence of the Malaria Mosquito Anopheles gambiae
journal, October 2002


Developing computational biology at meridian 23° E, and a little eastwards
journal, November 2018