Energy Conservation and Hydrogenase Function in Methanogenic Archaea, in Particular the Genus Methanosarcina
Abstract
The biological production of methane is vital to the global carbon cycle and accounts for ca. 74% of total methane emissions. The organisms that facilitate this process, methanogenic archaea, belong to a large and phylogenetically diverse group that thrives in a wide range of anaerobic environments. Two main subgroups exist within methanogenic archaea: those with and those without cytochromes. Although a variety of metabolisms exist within this group, the reduction of growth substrates to methane using electrons from molecular hydrogen is, in a phylogenetic sense, the most widespread methanogenic pathway. Methanogens without cytochromes typically generate methane by the reduction of CO2 with electrons derived from H2, formate, or secondary alcohols, generating a transmembrane ion gradient for ATP production via an Na+-translocating methyltransferase (Mtr). These organisms also conserve energy with a novel flavin-based electron bifurcation mechanism, wherein the endergonic reduction of ferredoxin is facilitated by the exergonic reduction of a disulfide terminal electron acceptor coupled to either H2 or formate oxidation. Methanogens that utilize cytochromes have a broader substrate range, and can convert acetate and methylated compounds to methane, in addition to the ability to reduce CO2. Cytochrome-containing methanogens are able to supplement the ion motive force generated by Mtr withmore »
- Publication Date:
- Research Org.:
- William W. Metcalf (University of Illinois at Urbana-Champaign
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22). Chemical Sciences, Geosciences & Biosciences Division
- OSTI Identifier:
- 1595766
- Grant/Contract Number:
- FG02-02ER15296
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Microbiology and Molecular Biology Reviews
- Additional Journal Information:
- Journal Volume: 83; Journal Issue: 4; Journal ID: ISSN 1092-2172
- Publisher:
- American Society for Microbiology
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; archaea; energy conservation; hydrogenase; methanogenesis
Citation Formats
Mand, Thomas D., and Metcalf, William W. Energy Conservation and Hydrogenase Function in Methanogenic Archaea, in Particular the Genus Methanosarcina. United States: N. p., 2019.
Web. doi:10.1128/MMBR.00020-19.
Mand, Thomas D., & Metcalf, William W. Energy Conservation and Hydrogenase Function in Methanogenic Archaea, in Particular the Genus Methanosarcina. United States. doi:10.1128/MMBR.00020-19.
Mand, Thomas D., and Metcalf, William W. Wed .
"Energy Conservation and Hydrogenase Function in Methanogenic Archaea, in Particular the Genus Methanosarcina". United States. doi:10.1128/MMBR.00020-19. https://www.osti.gov/servlets/purl/1595766.
@article{osti_1595766,
title = {Energy Conservation and Hydrogenase Function in Methanogenic Archaea, in Particular the Genus Methanosarcina},
author = {Mand, Thomas D. and Metcalf, William W.},
abstractNote = {The biological production of methane is vital to the global carbon cycle and accounts for ca. 74% of total methane emissions. The organisms that facilitate this process, methanogenic archaea, belong to a large and phylogenetically diverse group that thrives in a wide range of anaerobic environments. Two main subgroups exist within methanogenic archaea: those with and those without cytochromes. Although a variety of metabolisms exist within this group, the reduction of growth substrates to methane using electrons from molecular hydrogen is, in a phylogenetic sense, the most widespread methanogenic pathway. Methanogens without cytochromes typically generate methane by the reduction of CO2 with electrons derived from H2, formate, or secondary alcohols, generating a transmembrane ion gradient for ATP production via an Na+-translocating methyltransferase (Mtr). These organisms also conserve energy with a novel flavin-based electron bifurcation mechanism, wherein the endergonic reduction of ferredoxin is facilitated by the exergonic reduction of a disulfide terminal electron acceptor coupled to either H2 or formate oxidation. Methanogens that utilize cytochromes have a broader substrate range, and can convert acetate and methylated compounds to methane, in addition to the ability to reduce CO2. Cytochrome-containing methanogens are able to supplement the ion motive force generated by Mtr with an H+-translocating electron transport system. In both groups, enzymes known as hydrogenases, which reversibly interconvert protons and electrons to molecular hydrogen, play a central role in the methanogenic process. In this review, we discuss recent insight into methanogen metabolism and energy conservation mechanisms with a particular focus on the genus Methanosarcina.},
doi = {10.1128/MMBR.00020-19},
journal = {Microbiology and Molecular Biology Reviews},
number = 4,
volume = 83,
place = {United States},
year = {2019},
month = {9}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 1 work
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD+ (Rnf) as Electron Acceptors: A Historical Review
journal, March 2018
- Buckel, Wolfgang; Thauer, Rudolf K.
- Frontiers in Microbiology, Vol. 9
Heterodisulfide reductase from methanogenic archaea: a new catalytic role for an iron-sulfur cluster
journal, January 2005
- Hedderich, Reiner; Hamann, Nils; Bennati, Marina
- Biological Chemistry, Vol. 386, Issue 10
Genetic, Biochemical, and Molecular Characterization of Methanosarcina barkeri Mutants Lacking Three Distinct Classes of Hydrogenase
journal, July 2018
- Mand, Thomas D.; Kulkarni, Gargi; Metcalf, William W.
- Journal of Bacteriology, Vol. 200, Issue 20
Hydrogen is a preferred intermediate in the energy-conserving electron transport chain of Methanosarcina barkeri
journal, September 2009
- Kulkarni, Gargi; Kridelbaugh, Donna M.; Guss, Adam M.
- Proceedings of the National Academy of Sciences, Vol. 106, Issue 37
Biochemistry, evolution and physiological function of the Rnf complex, a novel ion-motive electron transport complex in prokaryotes
journal, November 2010
- Biegel, Eva; Schmidt, Silke; González, José M.
- Cellular and Molecular Life Sciences, Vol. 68, Issue 4
Hydrogen concentrations in methane-forming cells probed by the ratios of reduced and oxidized coenzyme F420
journal, May 2005
- de Poorter, L. M. I.
- Microbiology, Vol. 151, Issue 5
Novel reactions involved in energy conservation by methanogenic archaea
journal, September 1999
- Deppenmeier, Uwe; Lienard, Tanja; Gottschalk, Gerhard
- FEBS Letters, Vol. 457, Issue 3
Clostridium ultunense sp. nov., a Mesophilic Bacterium Oxidizing Acetate in Syntrophic Association with a Hydrogenotrophic Methanogenic Bacterium
journal, October 1996
- Schnurer, A.; Schink, B.; Svensson, B. H.
- International Journal of Systematic Bacteriology, Vol. 46, Issue 4
Energy Conservation via Hydrogen Cycling in the Methanogenic Archaeon Methanosarcina barkeri
journal, July 2018
- Kulkarni, Gargi; Mand, Thomas D.; Metcalf, William W.
- mBio, Vol. 9, Issue 4
Heterodisulfide Reductase from Methanol-Grown Cells of Methanosarcina Barkeri is not a Flavoenzyme
journal, February 1997
- Kunkel, Andreas; Vaupel, Martin; Heim, Steffen
- European Journal of Biochemistry, Vol. 244, Issue 1
Tight Coupling of Partial Reactions in the Acetyl-CoA Decarbonylase/Synthase (ACDS) Multienzyme Complex from Methanosarcina thermophila : ACETYL C–C BOND FRAGMENTATION AT THE A CLUSTER PROMOTED BY PROTEIN CONFORMATIONAL CHANGES
journal, March 2010
- Gencic, Simonida; Duin, Evert C.; Grahame, David A.
- Journal of Biological Chemistry, Vol. 285, Issue 20
Differences in Hydrogenase Gene Expression between Methanosarcina acetivorans and Methanosarcina barkeri
journal, February 2009
- Guss, A. M.; Kulkarni, G.; Metcalf, W. W.
- Journal of Bacteriology, Vol. 191, Issue 8
Methanofollis ethanolicus sp. nov., an ethanol-utilizing methanogen isolated from a lotus field
journal, April 2009
- Imachi, H.; Sakai, S.; Nagai, H.
- INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 59, Issue 4
The F 420 H 2 :heterodisulfide oxidoreductase system from Methanosarcina species : 2-Hydroxyphenazine mediates electron transfer from F
journal, May 1998
- Bäumer, Sebastian; Murakami, Eisuke; Brodersen, Jens
- FEBS Letters, Vol. 428, Issue 3
Purification and Properties of the Heme- and Iron−Sulfur-Containing Heterodisulfide Reductase from Methanosarcina thermophila †
journal, July 1998
- Simianu, Mihaela; Murakami, Eisuke; Brewer, John M.
- Biochemistry, Vol. 37, Issue 28
Coupling of ATP synthesis and methane formation from methanol and molecular hydrogen in Methanosarcina barkeri
journal, May 1984
- Blaut, Michael; Gottschalk, Gerhard
- European Journal of Biochemistry, Vol. 141, Issue 1
Biochemistry of methanogenesis: a tribute to Marjory Stephenson:1998 Marjory Stephenson Prize Lecture
journal, September 1998
- Thauer, R. K.
- Microbiology, Vol. 144, Issue 9
Purification and characterization of membrane-bound hydrogenase from Methanosarcina barkeri MS
journal, January 1994
- Kemner, John M.; Zeikus, J. Gregory
- Archives of Microbiology, Vol. 161, Issue 1
Methanomassiliicoccus luminyensis gen. nov., sp. nov., a methanogenic archaeon isolated from human faeces
journal, August 2012
- Dridi, B.; Fardeau, M. -L.; Ollivier, B.
- INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 62, Issue Pt 8
Growth of acetotrophic, methane-producing bacteria in a pH auxostat
journal, July 1984
- Sowers, Kevin R.; Nelson, Michael J.; Ferry, James G.
- Current Microbiology, Vol. 11, Issue 4
Methanonatronarchaeum thermophilum gen. nov., sp. nov. and 'Candidatus Methanohalarchaeum thermophilum', extremely halo(natrono)philic methyl-reducing methanogens from hypersaline lakes comprising a new euryarchaeal class Methanonatronarchaeia classis nov.
journal, July 2018
- Sorokin, Dimitry Y.; Merkel, Alexander Y.; Abbas, Ben
- International Journal of Systematic and Evolutionary Microbiology, Vol. 68, Issue 7
Thermacetogenium phaeum gen. nov., sp. nov., a strictly anaerobic, thermophilic, syntrophic acetate-oxidizing bacterium
journal, July 2000
- Hattori, S.; Kamagata, Y.; Hanada, S.
- INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 50, Issue 4
[FeFe]- and [NiFe]-hydrogenase diversity, mechanism, and maturation
journal, June 2015
- Peters, John W.; Schut, Gerrit J.; Boyd, Eric S.
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1853, Issue 6
The Membrane-Bound Electron Transport System of Methanosarcina Species
journal, February 2004
- Deppenmeier, Uwe
- Journal of Bioenergetics and Biomembranes, Vol. 36, Issue 1
Classification of secondary alcohol-utilizing methanogens including a new thermophilic isolate
journal, September 1988
- Widdel, F.; Rouvi�re, P. E.; Wolfe, R. S.
- Archives of Microbiology, Vol. 150, Issue 5
Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation
journal, April 2002
- Meuer, J.; Kuettner, H. C.; Zhang, J. K.
- Proceedings of the National Academy of Sciences, Vol. 99, Issue 8
Bioenergetics of Archaea: ATP Synthesis under Harsh Environmental Conditions
journal, January 2005
- Müller, V.; Lemker, T.; Lingl, A.
- Journal of Molecular Microbiology and Biotechnology, Vol. 10, Issue 2-4
Growth Characteristics of Methanomassiliicoccus luminyensis and Expression of Methyltransferase Encoding Genes
journal, January 2017
- Kröninger, Lena; Gottschling, Jacqueline; Deppenmeier, Uwe
- Archaea, Vol. 2017
Methanococcus maripaludis Employs Three Functional Heterodisulfide Reductase Complexes for Flavin-Based Electron Bifurcation Using Hydrogen and Formate
journal, July 2018
- Milton, Ross D.; Ruth, John C.; Deutzmann, Jörg S.
- Biochemistry, Vol. 57, Issue 32
Function of H 2 -forming methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum in coenzyme F 420 reduction with H 2
journal, February 1998
- Afting, C.; Hochheimer, A.; Thauer, R. K.
- Archives of Microbiology, Vol. 169, Issue 3
Coupling of carbon monoxide oxidation to CO2 and H2 with the phosphorylation of ADP in acetate-grown Methanosarcina barkeri
journal, September 1986
- Bott, Michael; Eikmanns, Bernhard; Thauer, Rudolf K.
- European Journal of Biochemistry, Vol. 159, Issue 2
Involvement of Ech hydrogenase in energy conservation of Methanosarcina mazei: Function of Ech in energy conservation
journal, July 2010
- Welte, Cornelia; Krätzer, Christian; Deppenmeier, Uwe
- FEBS Journal, Vol. 277, Issue 16
Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea
journal, July 2000
- Beifuss, Uwe; Tietze, Mario; Bäumer, Sebastian
- Angewandte Chemie International Edition, Vol. 39, Issue 14
Classification and phylogeny of hydrogenases
journal, August 2001
- Vignais, Paulette M.; Billoud, Bernard; Meyer, Jacques
- FEMS Microbiology Reviews, Vol. 25, Issue 4, p. 455-501
Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase
journal, June 2010
- Costa, K. C.; Wong, P. M.; Wang, T.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue 24
Chasing the elusive Euryarchaeota class WSA2: genomes reveal a uniquely fastidious methyl-reducing methanogen
journal, March 2016
- Nobu, Masaru Konishi; Narihiro, Takashi; Kuroda, Kyohei
- The ISME Journal, Vol. 10, Issue 10
Methanosphaera stadtmaniae gen. nov., sp. nov.: a species that forms methane by reducing methanol with hydrogen
journal, March 1985
- Miller, Terry L.; Wolin, Meyer J.
- Archives of Microbiology, Vol. 141, Issue 2
Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens
journal, February 2019
- Berghuis, Bojk A.; Yu, Feiqiao Brian; Schulz, Frederik
- Proceedings of the National Academy of Sciences, Vol. 116, Issue 11
Non-aceticlastic methanogenesis from acetate: acetate oxidation by a thermophilic syntrophic coculture
journal, July 1984
- Zinder, Stephen H.; Koch, Markus
- Archives of Microbiology, Vol. 138, Issue 3
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
journal, October 2007
- Vignais, Paulette M.; Billoud, Bernard
- Chemical Reviews, Vol. 107, Issue 10, p. 4206-4272
Candidatus Methanogranum caenicola: a Novel Methanogen from the Anaerobic Digested Sludge, and Proposal of Methanomassiliicoccaceae fam. nov. and Methanomassiliicoccales ord. nov., for a Methanogenic Lineage of the Class Thermoplasmata
journal, January 2013
- Iino, Takao; Tamaki, Hideyuki; Tamazawa, Satoshi
- Microbes and Environments, Vol. 28, Issue 2
Genetic analysis of mch mutants in two Methanosarcina species demonstrates multiple roles for the methanopterin-dependent C-1 oxidation/reduction pathway and differences in H 2 metabolism between closely related species : Methyl reduction in
journal, January 2005
- Guss, Adam M.; Mukhopadhyay, Biswarup; Zhang, Jun Kai
- Molecular Microbiology, Vol. 55, Issue 6
8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization
journal, July 1987
- Fox, Judith A.; Livingston, David J.; Orme-Johnson, William H.
- Biochemistry, Vol. 26, Issue 14
The F 420 H 2 Dehydrogenase from Methanosarcina mazei Is a Redox-driven Proton Pump Closely Related to NADH Dehydrogenases
journal, April 2000
- Bäumer, Sebastian; Ide, Tina; Jacobi, Carsten
- Journal of Biological Chemistry, Vol. 275, Issue 24
Methanococcus jannaschii sp. nov., an extremely thermophilic methanogen from a submarine hydrothermal vent
journal, December 1983
- Jones, W. J.; Leigh, J. A.; Mayer, F.
- Archives of Microbiology, Vol. 136, Issue 4
Energy-Converting [NiFe] Hydrogenases: More than Just H<sub>2</sub> Activation
journal, January 2005
- Hedderich, Reiner; Forzi, Lucia
- Journal of Molecular Microbiology and Biotechnology, Vol. 10, Issue 2-4
Molecular characterization of methanogenic N 5 -methyl-tetrahydromethanopterin: Coenzyme M methyltransferase
journal, September 2016
- Upadhyay, Vikrant; Ceh, Katharina; Tumulka, Franz
- Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1858, Issue 9
Re-evaluation of the function of the F420 dehydrogenase in electron transport of Methanosarcina mazei: Role of F420 dehydrogenase in Ms. mazei
journal, March 2011
- Welte, Cornelia; Deppenmeier, Uwe
- FEBS Journal, Vol. 278, Issue 8
The Na+-translocating methyltransferase complex from methanogenic archaea
journal, May 2001
- Gottschalk, Gerhard; Thauer, Rudolf K.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1505, Issue 1
Purification of the F420-reducing hydrogenase from Methanosarcina barkeri (strain Fusaro)
journal, September 1989
- Fiebig, Klaus; Friedrich, Barbel
- European Journal of Biochemistry, Vol. 184, Issue 1
Genome Sequence of "Candidatus Methanomassiliicoccus intestinalis" Issoire-Mx1, a Third Thermoplasmatales-Related Methanogenic Archaeon from Human Feces
journal, June 2013
- Borrel, G.; Harris, H. M. B.; Parisot, N.
- Genome Announcements, Vol. 1, Issue 4
The transmembrane electrochemical gradient of Na+ as driving force for methanol oxidation in Methanosarcina barkeri
journal, March 1988
- Muller, Volker; Blaut, Michael; Gottschalk, Gerhard
- European Journal of Biochemistry, Vol. 172, Issue 3
Genome Sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens
journal, December 2012
- Borrel, G.; Harris, H. M. B.; Tottey, W.
- Journal of Bacteriology, Vol. 194, Issue 24
The Reaction Mechanism of Methyl-Coenzyme M Reductase: HOW AN ENZYME ENFORCES STRICT BINDING ORDER
journal, February 2015
- Wongnate, Thanyaporn; Ragsdale, Stephen W.
- Journal of Biological Chemistry, Vol. 290, Issue 15
Methanogenesis and the Wood–Ljungdahl Pathway: An Ancient, Versatile, and Fragile Association
journal, May 2016
- Borrel, Guillaume; Adam, Panagiotis S.; Gribaldo, Simonetta
- Genome Biology and Evolution, Vol. 8, Issue 6
Cell proliferation at 122 C and isotopically heavy CH4 production by a hyperthermophilic methanogen under high-pressure cultivation
journal, July 2008
- Takai, K.; Nakamura, K.; Toki, T.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 31
Reduced coenzyme F420: heterodisulfide oxidoreductase, a proton- translocating redox system in methanogenic bacteria.
journal, December 1990
- Deppenmeier, U.; Blaut, M.; Mahlmann, A.
- Proceedings of the National Academy of Sciences, Vol. 87, Issue 23
Electron transport during aceticlastic methanogenesis by Methanosarcina acetivorans involves a sodium-translocating Rnf complex
journal, November 2012
- Schlegel, Katharina; Welte, Cornelia; Deppenmeier, Uwe
- FEBS Journal, Vol. 279, Issue 24
Coupling of ferredoxin and heterodisulfide reduction via electron bifurcation in hydrogenotrophic methanogenic archaea
journal, January 2011
- Kaster, A. -K.; Moll, J.; Parey, K.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 7
Proton translocation coupled to the oxidation of carbon monoxide to CO2 and H2 in Methanosarcina barkeri
journal, February 1989
- Bott, Michael; Thauer, Rudolf K.
- European Journal of Biochemistry, Vol. 179, Issue 2
Energy-Converting [NiFe] Hydrogenases from Archaea and Extremophiles: Ancestors of Complex I
journal, February 2004
- Hedderich, Reiner
- Journal of Bioenergetics and Biomembranes, Vol. 36, Issue 1
Methane from acetate.
journal, September 1992
- Ferry, J. G.
- Journal of Bacteriology, Vol. 174, Issue 17
Immunocytochemical localization of the coenzyme F420-reducing hydrogenase in Methanosarcina barkeri Fusaro.
journal, January 1991
- Lünsdorf, H.; Niedrig, M.; Fiebig, K.
- Journal of Bacteriology, Vol. 173, Issue 3
Physiology, Biochemistry, and Applications of F 420 - and F o -Dependent Redox Reactions
journal, April 2016
- Greening, Chris; Ahmed, F. Hafna; Mohamed, A. Elaaf
- Microbiology and Molecular Biology Reviews, Vol. 80, Issue 2
Syntrophic Acetate-Oxidizing Microbes in Methanogenic Environments
journal, January 2008
- Hattori, Satoshi
- Microbes and Environments, Vol. 23, Issue 2
De novo modeling of the F420-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy
journal, March 2013
- Mills, Deryck J.; Vitt, Stella; Strauss, Mike
- eLife, Vol. 2
Assignment of the [4Fe-4S] clusters of Ech hydrogenase from Methanosarcina barkeri to individual subunits via the characterization of site-directed mutants
journal, September 2005
- Forzi, Lucia; Koch, Jurgen; Guss, Adam M.
- FEBS Journal, Vol. 272, Issue 18
An Escherichia coli hydrogenase-3-type hydrogenase in methanogenic archaea
journal, March 1998
- Kunkel, Andreas; Vorholt, Julia A.; Thauer, Rudolf K.
- European Journal of Biochemistry, Vol. 252, Issue 3
Analysis of the vhoGAC and vhtGAC Operons from Methanosarcina mazei Strain Go1, Both Encoding a Membrane-bound Hydrogenase and a Cytochrome b
journal, January 1995
- Deppenmeier, Uwe; Blaut, Michael; Lentes, Sabine
- European Journal of Biochemistry, Vol. 227, Issue 1-2
Different structure and expression of the operons encoding the membrane-bound hydrogenases fromMethanosarcina mazei Gö1
journal, November 1995
- Deppenmeier, Uwe
- Archives of Microbiology, Vol. 164, Issue 5
Methane metabolism in the archaeal phylum Bathyarchaeota revealed by genome-centric metagenomics
journal, October 2015
- Evans, P. N.; Parks, D. H.; Chadwick, G. L.
- Science, Vol. 350, Issue 6259
Enzymology of the fermentation of acetate to methane by Methanosarcina thermophila
journal, January 1997
- Ferry, James G.
- BioFactors, Vol. 6, Issue 1
Genetic Analysis of the Methanol- and Methylamine-Specific Methyltransferase 2 Genes of Methanosarcina acetivorans C2A
journal, March 2008
- Bose, A.; Pritchett, M. A.; Metcalf, W. W.
- Journal of Bacteriology, Vol. 190, Issue 11
Redox Potentials of Methanophenazine and CoB-S-S-CoM, Factors Involved in Electron Transport in Methanogenic Archaea
journal, March 2003
- Tietze, Mario; Beuchle, Anja; Lamla, Iris
- ChemBioChem, Vol. 4, Issue 4
Thermotoga lettingae sp. nov., a novel thermophilic, methanol-degrading bacterium isolated from a thermophilic anaerobic reactor.
journal, July 2002
- Stams, Alfons J. M.; Balk, Melike; Weijma, Jan
- International Journal of Systematic and Evolutionary Microbiology, Vol. 52, Issue 4
An evolving view of methane metabolism in the Archaea
journal, January 2019
- Evans, Paul N.; Boyd, Joel A.; Leu, Andy O.
- Nature Reviews Microbiology, Vol. 17, Issue 4
Genome Sequence of a Mesophilic Hydrogenotrophic Methanogen Methanocella paludicola, the First Cultivated Representative of the Order Methanocellales
journal, July 2011
- Sakai, Sanae; Takaki, Yoshihiro; Shimamura, Shigeru
- PLoS ONE, Vol. 6, Issue 7
Purification and characterization of coenzyme F420-dependent 5,10-methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum strain ΔH
journal, January 1991
- te Brömmelstroet, B. W.; Hensgens, Charles M. H.; Keltjens, Jan T.
- Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1073, Issue 1
Cloning, sequence determination, and expression of the genes encoding the subunits of the nickel-containing 8-hydroxy-5-deazaflavin reducing hydrogenase from Methanobacterium thermoautotrophicum .DELTA.H
journal, August 1990
- Alex, Lisa A.; Reeve, John N.; Orme-Johnson, William H.
- Biochemistry, Vol. 29, Issue 31
Methane Feedbacks to the Global Climate System in a Warmer World
journal, March 2018
- Dean, Joshua F.; Middelburg, Jack J.; Röckmann, Thomas
- Reviews of Geophysics, Vol. 56, Issue 1
A Ferredoxin- and F 420 H 2 -Dependent, Electron-Bifurcating, Heterodisulfide Reductase with Homologs in the Domains Bacteria and Archaea
journal, February 2017
- Yan, Zhen; Wang, Mingyu; Ferry, James G.
- mBio, Vol. 8, Issue 1
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase of Methanosarcina strain Gö1 is an Na(+)-translocating membrane protein.
journal, December 1992
- Becher, B.; Müller, V.; Gottschalk, G.
- Journal of Bacteriology, Vol. 174, Issue 23
Electron transport in acetate-grown Methanosarcina acetivorans
journal, January 2011
- Wang, Mingyu; Tomb, Jean-Francois; Ferry, James G.
- BMC Microbiology, Vol. 11, Issue 1
Evolution of Na + and H + bioenergetics in methanogenic archaea
journal, February 2013
- Schlegel, Katharina; Müller, Volker
- Biochemical Society Transactions, Vol. 41, Issue 1
Genome-Scale Metabolic Reconstruction and Hypothesis Testing in the Methanogenic Archaeon Methanosarcina acetivorans C2A
journal, December 2011
- Benedict, M. N.; Gonnerman, M. C.; Metcalf, W. W.
- Journal of Bacteriology, Vol. 194, Issue 4
Promiscuous archaeal ATP synthase concurrently coupled to Na+ and H+ translocation
journal, January 2012
- Schlegel, K.; Leone, V.; Faraldo-Gomez, J. D.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 3
Sodium dependence of methane formation in methanogenic bacteria
journal, July 1982
- Perski, Hans Joachim; Schönheit, Peter; Thauer, Rudolf K.
- FEBS Letters, Vol. 143, Issue 2
Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis
journal, August 2012
- Lie, T. J.; Costa, K. C.; Lupa, B.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 38
Proton-motive-force-driven formation of CO from CO2 and H2 in methanogenic bacteria
journal, October 1987
- Bott, Michael; Thauer, Rudolf K.
- European Journal of Biochemistry, Vol. 168, Issue 2
Thermodynamics of the Formylmethanofuran Dehydrogenase Reaction in Methanobacterium Thermoautotrophicum
journal, December 1994
- Bertram, Peter A.; Thauer, Rudolf K.
- European Journal of Biochemistry, Vol. 226, Issue 3
Regulation of the synthesis of H 2 -forming methylenetetrahydromethanopterin dehydrogenase (Hmd) and of HmdII and HmdIII in Methanothermobacter marburgensis
journal, September 2000
- Afting, Christina; Kremmer, Elisabeth; Brucker, Claudia
- Archives of Microbiology, Vol. 174, Issue 4
MrpA Functions in Energy Conversion during Acetate-Dependent Growth of Methanosarcina acetivorans
journal, July 2013
- Jasso-Chavez, R.; Apolinario, E. E.; Sowers, K. R.
- Journal of Bacteriology, Vol. 195, Issue 17
Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase
journal, February 2010
- Buan, Nicole R.; Metcalf, William W.
- Molecular Microbiology, Vol. 75, Issue 4
Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulfide reductase reactions in Methanothermobacter thermautotrophicus: Bioenergetics of H2-dependent methanogenic reactions
journal, December 2002
- De Poorter, Linda M. I.; Geerts, Wim G.; Theuvenet, Alexander P. R.
- European Journal of Biochemistry, Vol. 270, Issue 1
Purification and catalytic properties of Ech hydrogenase from Methanosarcina barkeri
journal, October 1999
- Meuer, Jorn; Bartoschek, Stefan; Koch, Jurgen
- European Journal of Biochemistry, Vol. 265, Issue 1
My Kind of Biology
journal, October 1991
- Wolfe, Ralph S.
- Annual Review of Microbiology, Vol. 45, Issue 1
Membrane targeting and translocation of bacterial hydrogenases
journal, March 2000
- Wu, Long-Fei; Chanal, Angélique; Rodrigue, Agnès
- Archives of Microbiology, Vol. 173, Issue 5-6
Metabolic, Phylogenetic, and Ecological Diversity of the Methanogenic Archaea
journal, March 2008
- Liu, Yuchen; Whitman, William B.
- Annals of the New York Academy of Sciences, Vol. 1125, Issue 1
Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation
journal, February 2013
- Buckel, Wolfgang; Thauer, Rudolf K.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1827, Issue 2
Differences down-under: alcohol-fueled methanogenesis by archaea present in Australian macropodids
journal, March 2016
- Hoedt, Emily C.; Cuív, Páraic Ó; Evans, Paul N.
- The ISME Journal, Vol. 10, Issue 10
Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri.
journal, January 1990
- te Brömmelstroet, B. W.; Hensgens, C. M.; Geerts, W. J.
- Journal of Bacteriology, Vol. 172, Issue 2
Judicial Commission of the International Committee on Systematics of Prokaryotes * XIIth International (IUMS) Congress of Bacteriology and Applied Microbiology: Minutes of the meetings, 3, 4 and 6 August 2008, Istanbul, Turkey
journal, November 2011
- Garrity, G. M.; Labeda, D. P.; Oren, A.
- INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 61, Issue 11
The Wolfe cycle comes full circle
journal, September 2012
- Thauer, R. K.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 38
Bioenergetics and anaerobic respiratory chains of aceticlastic methanogens
journal, July 2014
- Welte, Cornelia; Deppenmeier, Uwe
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1837, Issue 7
The Crystal Structure of [Fe]-Hydrogenase Reveals the Geometry of the Active Site
journal, July 2008
- Shima, S.; Pilak, O.; Vogt, S.
- Science, Vol. 321, Issue 5888
Methanogens: biochemical background and biotechnological applications
journal, January 2018
- Enzmann, Franziska; Mayer, Florian; Rother, Michael
- AMB Express, Vol. 8, Issue 1
Methanogenic archaea: ecologically relevant differences in energy conservation
journal, June 2008
- Thauer, Rudolf K.; Kaster, Anne-Kristin; Seedorf, Henning
- Nature Reviews Microbiology, Vol. 6, Issue 8
Methylotrophic methanogenesis discovered in the archaeal phylum Verstraetearchaeota
journal, October 2016
- Vanwonterghem, Inka; Evans, Paul N.; Parks, Donovan H.
- Nature Microbiology, Vol. 1, Issue 12
Antigenic determinants of the membrane-bound hydrogenase in Alcaligenes eutrophus are exposed toward the periplasm.
journal, January 1995
- Eismann, K.; Mlejnek, K.; Zipprich, D.
- Journal of bacteriology, Vol. 177, Issue 21
Methanopyrus kandleri, gen. and sp. nov. represents a novel group of hyperthermophilic methanogens, growing at 110�C
journal, September 1991
- Kurr, Margit; Huber, Robert; K�nig, Helmut
- Archives of Microbiology, Vol. 156, Issue 4
Electron Transport in the Pathway of Acetate Conversion to Methane in the Marine Archaeon Methanosarcina acetivorans
journal, December 2005
- Li, Q.; Li, L.; Rejtar, T.
- Journal of Bacteriology, Vol. 188, Issue 2
The Genome Sequence of Methanosphaera stadtmanae Reveals Why This Human Intestinal Archaeon Is Restricted to Methanol and H2 for Methane Formation and ATP Synthesis
journal, December 2005
- Fricke, W. F.; Seedorf, H.; Henne, A.
- Journal of Bacteriology, Vol. 188, Issue 2
Characterization of the RnfB and RnfG Subunits of the Rnf Complex from the Archaeon Methanosarcina acetivorans
journal, May 2014
- Suharti, Suharti; Wang, Mingyu; de Vries, Simon
- PLoS ONE, Vol. 9, Issue 5
N 5 , N 10 -Methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum has hydrogenase activity
journal, February 1990
- Zirngibl, C.; Hedderich, R.; Thauer, R. K.
- FEBS Letters, Vol. 261, Issue 1
Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae
journal, December 1987
- Muth, Erika; Morschel, Erhard; Klein, Albrecht
- European Journal of Biochemistry, Vol. 169, Issue 3
Rising atmospheric methane: 2007-2014 growth and isotopic shift: RISING METHANE 2007-2014
journal, September 2016
- Nisbet, E. G.; Dlugokencky, E. J.; Manning, M. R.
- Global Biogeochemical Cycles, Vol. 30, Issue 9
Methanocella paludicola gen. nov., sp. nov., a methane-producing archaeon, the first isolate of the lineage 'Rice Cluster I', and proposal of the new archaeal order Methanocellales ord. nov.
journal, April 2008
- Sakai, S.; Imachi, H.; Hanada, S.
- INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 58, Issue 4
Primary structure and properties of the formyltransferase from the mesophilic Methanosarcina barkeri: comparison with the enzymes from thermophilic and hyperthermophilic methanogens
journal, February 1996
- Kunow, Jasper; Shima, Seigo; Vorholt, Julia A.
- Archives of Microbiology, Vol. 165, Issue 2
Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum.
journal, January 1989
- Baron, S. F.; Ferry, J. G.
- Journal of Bacteriology, Vol. 171, Issue 7
Methane production from coal by a single methanogen
journal, October 2016
- Mayumi, D.; Mochimaru, H.; Tamaki, H.
- Science, Vol. 354, Issue 6309
Sodium dependence of growth and methane formation in Methanobacterium thermoautotrophicum
journal, January 1981
- Perski, Hans-Joachim; Moll, Johanna; Thauer, Rudolf K.
- Archives of Microbiology, Vol. 130, Issue 4
Hydrogenases from Methanogenic Archaea, Nickel, a Novel Cofactor, and H 2 Storage
journal, June 2010
- Thauer, Rudolf K.; Kaster, Anne-Kristin; Goenrich, Meike
- Annual Review of Biochemistry, Vol. 79, Issue 1
Methanobacterium thermoautotrophicum contains a soluble enzyme system that specifically catalyzes the reduction of the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate with H 2
journal, July 1988
- Hedderich, R.; Thauer, R. K.
- FEBS Letters, Vol. 234, Issue 1
Physiological role of the F 420 -non-reducing hydrogenase (Mvh) from Methanothermobacter marburgensis
journal, September 2003
- Stojanowic, Alexander; Mander, Gerd J.; Duin, Evert C.
- Archives of Microbiology, Vol. 180, Issue 3
Formylmethanofuran dehydrogenases from methanogenic Archaea Substrate specificity, EPR properties and reversible inactivation by cyanide of the molybdenum or tungsten iron-sulfur proteins
journal, March 1994
- Bertram, Peter A.; Karrasch, Marion; Schmitz, Ruth A.
- European Journal of Biochemistry, Vol. 220, Issue 2