Porous Chitin Microbeads for More Sustainable Cosmetics
Abstract
The microbead form is a material architecture that is promising for use in biomedical and cosmetic applications; however, the use of petroleum-based microbeads (i.e., plastics) has raised significant environmental concerns in recent years. Microbeads prepared from renewable polymers could represent a sustainable alternative to these synthetic microbeads. This work explores the use of chitin in preparing biodegradable, biocompatible microbeads of low toxicity. Chitin microbeads were synthesized using the ionic liquid (IL) 1-ethyl-3-methylimidazo-lium acetate ([C2mim][OAc]); the IL was used to both extract chitin directly from waste shrimp shell and to prepare the porous microbeads by coagulation in polypropylene glycol (PPG). The effects of biopolymer source and bead-preparation parameters on the formation of beads were investigated, as well as the effects of the drying conditions on the dry bead structure. It was found that IL-extracted chitin could be used to prepare beads of homogeneous size distribution (with 60% of beads 125-250 μm) and shape, while commercially available practical grade chitin could not, suggesting that high molecular weight chitin is required for bead-material formation. Supercritical CO2 drying and lyophilization of the wet beads led to dry chitin beads with an opaque appearance, porous interiors, and uniform shape. Loading and release studies of representativemore »
- Authors:
-
- McGill Univ., Montreal, QC (Canada). Dept. of Chemistry
- Mari Signum, Ltd., Rockville, MD (United States)
- Univ. of Alabama, Tuscaloosa, AL (United States). Dept. of Chemistry
- McGill Univ., Montreal, QC (Canada). Dept. of Chemistry; Univ. of Alabama, Tuscaloosa, AL (United States). Dept. of Chemistry; 525 Solutions, Inc., Tuscaloosa, AL (United States)
- Publication Date:
- Research Org.:
- Univ. of Alabama, Tuscaloosa, AL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); Canada Excellence Research Chairs (CERC) Program
- OSTI Identifier:
- 1593138
- Alternate Identifier(s):
- OSTI ID: 1593139
- Grant/Contract Number:
- SC0010152
- Resource Type:
- Accepted Manuscript
- Journal Name:
- ACS Sustainable Chemistry & Engineering
- Additional Journal Information:
- Journal Volume: 5; Journal Issue: 12; Journal ID: ISSN 2168-0485
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; Microspheres; Porous beads; Chitin; Ionic liquids; Cosmetic microbeads; Microspheres, Porous beads, Chitin, Ionic liquids, Cosmetic microbeads
Citation Formats
King, Catherine A., Shamshina, Julia L., Zavgorodnya, Oleksandra, Cutfield, Tatum, Block, Leah E., and Rogers, Robin D. Porous Chitin Microbeads for More Sustainable Cosmetics. United States: N. p., 2017.
Web. doi:10.1021/acssuschemeng.7b03053.
King, Catherine A., Shamshina, Julia L., Zavgorodnya, Oleksandra, Cutfield, Tatum, Block, Leah E., & Rogers, Robin D. Porous Chitin Microbeads for More Sustainable Cosmetics. United States. https://doi.org/10.1021/acssuschemeng.7b03053
King, Catherine A., Shamshina, Julia L., Zavgorodnya, Oleksandra, Cutfield, Tatum, Block, Leah E., and Rogers, Robin D. Mon .
"Porous Chitin Microbeads for More Sustainable Cosmetics". United States. https://doi.org/10.1021/acssuschemeng.7b03053. https://www.osti.gov/servlets/purl/1593138.
@article{osti_1593138,
title = {Porous Chitin Microbeads for More Sustainable Cosmetics},
author = {King, Catherine A. and Shamshina, Julia L. and Zavgorodnya, Oleksandra and Cutfield, Tatum and Block, Leah E. and Rogers, Robin D.},
abstractNote = {The microbead form is a material architecture that is promising for use in biomedical and cosmetic applications; however, the use of petroleum-based microbeads (i.e., plastics) has raised significant environmental concerns in recent years. Microbeads prepared from renewable polymers could represent a sustainable alternative to these synthetic microbeads. This work explores the use of chitin in preparing biodegradable, biocompatible microbeads of low toxicity. Chitin microbeads were synthesized using the ionic liquid (IL) 1-ethyl-3-methylimidazo-lium acetate ([C2mim][OAc]); the IL was used to both extract chitin directly from waste shrimp shell and to prepare the porous microbeads by coagulation in polypropylene glycol (PPG). The effects of biopolymer source and bead-preparation parameters on the formation of beads were investigated, as well as the effects of the drying conditions on the dry bead structure. It was found that IL-extracted chitin could be used to prepare beads of homogeneous size distribution (with 60% of beads 125-250 μm) and shape, while commercially available practical grade chitin could not, suggesting that high molecular weight chitin is required for bead-material formation. Supercritical CO2 drying and lyophilization of the wet beads led to dry chitin beads with an opaque appearance, porous interiors, and uniform shape. Loading and release studies of representative active compounds (indigo dye and sodium salicylate) into the chitin beads indicated that the dry beads could be easily loaded from an aqueous solution of active and could release 90% of the active compound within 7 h in deionized (DI) water at room temperature.},
doi = {10.1021/acssuschemeng.7b03053},
journal = {ACS Sustainable Chemistry & Engineering},
number = 12,
volume = 5,
place = {United States},
year = {Mon Oct 30 00:00:00 EDT 2017},
month = {Mon Oct 30 00:00:00 EDT 2017}
}
Web of Science
Works referenced in this record:
Scientific Evidence Supports a Ban on Microbeads
journal, July 2015
- Rochman, Chelsea M.; Kross, Sara M.; Armstrong, Jonathan B.
- Environmental Science & Technology, Vol. 49, Issue 18
The present and future of microplastic pollution in the marine environment
journal, February 2014
- Ivar do Sul, Juliana A.; Costa, Monica F.
- Environmental Pollution, Vol. 185
Functional polymer microspheres
journal, October 2000
- Kawaguchi, Haruma
- Progress in Polymer Science, Vol. 25, Issue 8
Biocompatibility of microparticles into soft tissue fillers
journal, December 2004
- Laeschke, Klaus
- Seminars in Cutaneous Medicine and Surgery, Vol. 23, Issue 4
Polymeric Microspheres for Medical Applications
journal, June 2010
- Saralidze, Ketie; Koole, Leo H.; Knetsch, Menno L. W.
- Materials, Vol. 3, Issue 6
The pollution of the marine environment by plastic debris: a review
journal, September 2002
- Derraik, José G. B.
- Marine Pollution Bulletin, Vol. 44, Issue 9
Characterisation, quantity and sorptive properties of microplastics extracted from cosmetics
journal, October 2015
- Napper, Imogen E.; Bakir, Adil; Rowland, Steven J.
- Marine Pollution Bulletin, Vol. 99, Issue 1-2
Microplastic pollution in the surface waters of the Laurentian Great Lakes
journal, December 2013
- Eriksen, Marcus; Mason, Sherri; Wilson, Stiv
- Marine Pollution Bulletin, Vol. 77, Issue 1-2
Microplastics as contaminants in the marine environment: A review
journal, December 2011
- Cole, Matthew; Lindeque, Pennie; Halsband, Claudia
- Marine Pollution Bulletin, Vol. 62, Issue 12
Chemical Pollutants Sorbed to Ingested Microbeads from Personal Care Products Accumulate in Fish
journal, March 2016
- Wardrop, Peter; Shimeta, Jeff; Nugegoda, Dayanthi
- Environmental Science & Technology, Vol. 50, Issue 7
Microplastics in the marine environment
journal, August 2011
- Andrady, Anthony L.
- Marine Pollution Bulletin, Vol. 62, Issue 8
International policies to reduce plastic marine pollution from single-use plastics (plastic bags and microbeads): A review
journal, May 2017
- Xanthos, Dirk; Walker, Tony R.
- Marine Pollution Bulletin, Vol. 118, Issue 1-2
Green Polymer Chemistry and Bio-based Plastics: Dreams and Reality
journal, November 2012
- Mülhaupt, Rolf
- Macromolecular Chemistry and Physics, Vol. 214, Issue 2
Chitin and chitosan: Properties and applications
journal, July 2006
- Rinaudo, Marguerite
- Progress in Polymer Science, Vol. 31, Issue 7
Release characteristics of vitamin E incorporated chitosan microspheres and in vitro–in vivo evaluation for topical application
journal, March 2011
- Yenilmez, E.; Başaran, E.; Yazan, Y.
- Carbohydrate Polymers, Vol. 84, Issue 2
Biomedical applications of chitin and chitosan based nanomaterials—A short review
journal, September 2010
- Jayakumar, R.; Menon, Deepthy; Manzoor, K.
- Carbohydrate Polymers, Vol. 82, Issue 2
Application of chitin- and chitosan-based materials for enzyme immobilizations: a review
journal, August 2004
- Krajewska, Barbara
- Enzyme and Microbial Technology, Vol. 35, Issue 2-3
Dissolution or extraction of crustacean shells using ionic liquids to obtain high molecular weight purified chitin and direct production of chitin films and fibers
journal, January 2010
- Qin, Ying; Lu, Xingmei; Sun, Ning
- Green Chemistry, Vol. 12, Issue 6, 968-971
Chitin–calcium alginate composite fibers for wound care dressings spun from ionic liquid solution
journal, January 2014
- Shamshina, J. L.; Gurau, G.; Block, L. E.
- J. Mater. Chem. B, Vol. 2, Issue 25
Surface modification of ionic liquid-spun chitin fibers for the extraction of uranium from seawater: seeking the strength of chitin and the chemical functionality of chitosan
journal, January 2014
- Barber, Patrick S.; Kelley, Steven P.; Griggs, Chris S.
- Green Chem., Vol. 16, Issue 4
A platform for more sustainable chitin films from an ionic liquid process
journal, January 2017
- King, Catherine; Shamshina, Julia L.; Gurau, Gabriela
- Green Chemistry, Vol. 19, Issue 1
Electrospinning of chitin nanofibers directly from an ionic liquid extract of shrimp shells
journal, January 2013
- Barber, Patrick S.; Griggs, Chris S.; Bonner, Jonathan R.
- Green Chemistry, Vol. 15, Issue 3
Electrospinning Biopolymers from Ionic Liquids Requires Control of Different Solution Properties than Volatile Organic Solvents
journal, May 2017
- Zavgorodnya, Oleksandra; Shamshina, Julia L.; Bonner, Jonathan R.
- ACS Sustainable Chemistry & Engineering, Vol. 5, Issue 6
“Practical” Electrospinning of Biopolymers in Ionic Liquids
journal, December 2016
- Shamshina, Julia L.; Zavgorodnya, Oleksandra; Bonner, Jonathan R.
- ChemSusChem, Vol. 10, Issue 1
Ionic Liquid-Reconstituted Cellulose Composites as Solid Support Matrices for Biocatalyst Immobilization
journal, September 2005
- Turner, Megan B.; Spear, Scott K.; Holbrey, John D.
- Biomacromolecules, Vol. 6, Issue 5
Preparation and characterization of chitin beads as a wound dressing precursor
journal, January 2000
- Yusof, Nealda Leila Binte Muhammad; Lim, Lee Yong; Khor, Eugene
- Journal of Biomedical Materials Research, Vol. 54, Issue 1
Preparation of CM-chitin microspheres by complexation with iron(III) in w/o emulsion and their biodisposition characteristics in mice
journal, September 2000
- Hata, H.
- Biomaterials, Vol. 21, Issue 17
Factorial design, preparation and characterization of new beads formed from alginate, polyphosphate and glycerol gelling solution for microorganism microencapsulation
journal, April 2015
- dos Santos, G. F.; Locatelli, G. O.; Coêlho, D. A.
- Journal of Sol-Gel Science and Technology, Vol. 75, Issue 2
Reduction of acidity and removal of metal ions from coal mining effluents using chitosan microspheres
journal, October 2007
- Laus, Rogério; Geremias, Reginaldo; Vasconcelos, Helder L.
- Journal of Hazardous Materials, Vol. 149, Issue 2
Spray-Drying Microencapsulation of Anthocyanins by Natural Biopolymers: A Review
journal, March 2014
- Mahdavi, Sahar Akhavan; Jafari, Seid Mahdi; Ghorbani, Mohammad
- Drying Technology, Vol. 32, Issue 5
Fabrication of chitin microspheres and their multipurpose application as catalyst support and adsorbent
journal, April 2015
- Wang, Yuntao; Li, Yan; Liu, Shilin
- Carbohydrate Polymers, Vol. 120
Highly Biocompatible Nanofibrous Microspheres Self-Assembled from Chitin in NaOH/Urea Aqueous Solution as Cell Carriers
journal, February 2015
- Duan, Bo; Zheng, Xing; Xia, Zhixiong
- Angewandte Chemie International Edition, Vol. 54, Issue 17
Conferring Natural-Derived Porous Microspheres with Surface Multifunctionality through Facile Coordination-Enabled Self-Assembly Process
journal, March 2016
- Han, Pingping; Shi, Jiafu; Nie, Teng
- ACS Applied Materials & Interfaces, Vol. 8, Issue 12
Design and functionalization of chitin-based microsphere scaffolds
journal, January 2013
- Silva, Simone S.; Duarte, Ana Rita C.; Mano, João F.
- Green Chemistry, Vol. 15, Issue 11
Chitin/PLGA blend microspheres as a biodegradable drug-delivery system: phase-separation, degradation and release behavior
journal, August 2002
- Mi, Fwu-Long; Lin, Yi-Mei; Wu, Yu-Bey
- Biomaterials, Vol. 23, Issue 15
Magnetic chitosan microspheres: preparation and characterization
journal, February 2002
- Denkbaş, Emir Baki; Kiliçay, Ebru; Birlikseven, Cengiz
- Reactive and Functional Polymers, Vol. 50, Issue 3
Continuous Production of Cellulose Microbeads via Membrane Emulsification
journal, June 2017
- Coombs OBrien, James; Torrente-Murciano, Laura; Mattia, Davide
- ACS Sustainable Chemistry & Engineering, Vol. 5, Issue 7
Iron(II) cross-linked chitin-based gel beads: Preparation, magnetic property and adsorption of methyl orange
journal, October 2010
- Li, Guoxiang; Du, Yumin; Tao, Yongzhen
- Carbohydrate Polymers, Vol. 82, Issue 3
Surface tension of ionic liquids and ionic liquid solutions
journal, January 2012
- Tariq, Mohammad; Freire, Mara G.; Saramago, Benilde
- Chem. Soc. Rev., Vol. 41, Issue 2
Gas–liquid interface of room-temperature ionic liquids
journal, January 2010
- Santos, Cherry S.; Baldelli, Steven
- Chemical Society Reviews, Vol. 39, Issue 6
Studies on the controlled morphology and wettability of polystyrene surfaces by electrospinning or electrospraying
journal, September 2006
- Zheng, Jianfen; He, Aihua; Li, Junxing
- Polymer, Vol. 47, Issue 20
Effect of the degree of deacetylation on the thermal decomposition of chitin and chitosan nanofibers
journal, March 2010
- Nam, Young Sik; Park, Won Ho; Ihm, Daewoo
- Carbohydrate Polymers, Vol. 80, Issue 1
Chemistry of Aerogels and Their Applications
journal, November 2002
- Pierre, Alain C.; Pajonk, Gérard M.
- Chemical Reviews, Vol. 102, Issue 11
Chitin characterization by SEM, FTIR, XRD, and 13 C cross polarization/mass angle spinning NMR : Chitin Characterization
journal, June 2004
- Cárdenas, Galo; Cabrera, Gustavo; Taboada, Edelio
- Journal of Applied Polymer Science, Vol. 93, Issue 4
Degree of deacetylation of chitosan using conductometric titration and solid-state NMR
journal, August 1993
- Raymond, Louise; Morin, Frederick G.; Marchessault, Robert H.
- Carbohydrate Research, Vol. 246, Issue 1
The Crystal Structure of α-Chitin (Poly-N-Acetyl-D-Glucosamine)
journal, September 1957
- Carlström, Diego
- The Journal of Biophysical and Biochemical Cytology, Vol. 3, Issue 5
Mini-Review: Green sustainable processes using supercritical fluid carbon dioxide
journal, January 2009
- Ramsey, Edward; Sun, Qiubai; Zhang, Zhiqiang
- Journal of Environmental Sciences, Vol. 21, Issue 6
Supercritical Fluid Applications: Industrial Developments and Economic Issues
journal, October 2000
- Perrut, Michel
- Industrial & Engineering Chemistry Research, Vol. 39, Issue 12
Works referencing / citing this record:
Preparation of Polymer Microparticles through Nonaqueous Suspension Polycondensations. Part II—Effects of Operating Variables on Properties of Poly(butylene succinate)
journal, August 2018
- Dutra, Luciana; Souza, Márcio Nele; Pinto, José Carlos
- Macromolecular Reaction Engineering, Vol. 12, Issue 6
Microplastics pollution in Bangladesh: current scenario and future research perspective
journal, November 2019
- Karim, Md. Ekramul; Sanjee, Sohana Al; Mahmud, Shohel
- Chemistry and Ecology, Vol. 36, Issue 1
Use of Ionic Liquids in Chitin Biorefinery: A Systematic Review
journal, January 2020
- Shamshina, Julia L.; Berton, Paula
- Frontiers in Bioengineering and Biotechnology, Vol. 8
Preparation, Mechanical Properties, and Biocompatibility of Graphene Oxide-Reinforced Chitin Monofilament Absorbable Surgical Sutures
journal, April 2019
- Zhang, Wei; Yin, Bin; Xin, Yu
- Marine Drugs, Vol. 17, Issue 4