Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection

doi:10.3389/fcimb.2019.00466

Title: Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection

Authors:: Weaver, Jr., Alan J.; Brandenburg, Kenneth S.; Smith, Brian W.; Leung, Kai P.

Publication Date:: 2020-01-10

Sponsoring Org.:: USDOE

OSTI Identifier:: 1582453

Resource Type:: Published Article

Journal Name:: Frontiers in Cellular and Infection Microbiology

Additional Journal Information:: Journal Name: Frontiers in Cellular and Infection Microbiology Journal Volume: 9; Journal ID: ISSN 2235-2988

Publisher:: Frontiers Media SA

Country of Publication:: Switzerland

Language:: English

Citation Formats


                    Weaver, Jr., Alan J., Brandenburg, Kenneth S., Smith, Brian W., and Leung, Kai P. Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection.  Switzerland: N. p., 2020. 
        Web.  doi:10.3389/fcimb.2019.00466.

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                    Weaver, Jr., Alan J., Brandenburg, Kenneth S., Smith, Brian W., & Leung, Kai P. Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection.  Switzerland.  doi:10.3389/fcimb.2019.00466.

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                    Weaver, Jr., Alan J., Brandenburg, Kenneth S., Smith, Brian W., and Leung, Kai P. Fri .  
        "Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection".  Switzerland.  doi:10.3389/fcimb.2019.00466.

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@article{osti_1582453,

  title        = {Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection},

  author       = {Weaver, Jr., Alan J. and Brandenburg, Kenneth S. and Smith, Brian W. and Leung, Kai P.},

  abstractNote = {},

  doi          = {10.3389/fcimb.2019.00466},

  journal      = {Frontiers in Cellular and Infection Microbiology},

  number       = ,

  volume       = 9,

  place        = {Switzerland},

  year         = {2020},

  month        = {1}

}

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DOI: 10.3389/fcimb.2019.00466

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Works referenced in this record:

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Title: Comparative Analysis of the Host Response in a Rat Model of Deep-Partial and Full-Thickness Burn Wounds With Pseudomonas aeruginosa Infection

Citation Formats

Burns, biofilm and a new appraisal of burn wound sepsis journal, February 2010

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds journal, May 2008

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Formation of Pseudomonas aeruginosa Biofilms in Full-thickness Scald Burn Wounds in Rats journal, September 2019

Association of high mobility group box-1 protein levels with sepsis and outcome of severely burned patients journal, January 2011

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Marked increase of plasma hyaluronan after major thermal injury and infusion therapy journal, March 1991

Changes in plasma fibronectin levels in burn patients journal, April 1987

Calculation of a new Meeh constant and experimental determination of burn size journal, December 1996

Circulating fibronectin in burned patients journal, July 1983

Modeling trauma in rats: similarities to humans and potential pitfalls to consider journal, September 2019

The Effects of Infection of Thermal Injury by Pseudomonas Aeruginosa pao1 on the Murine Cytokine Response journal, November 2001

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Sepsis in the burn patient: a different problem than sepsis in the general population journal, August 2017

Treatment before transfer: the patient with burns journal, September 2001

Burn size determines the inflammatory and hypermetabolic response journal, January 2007

Pseudomonas infections in the thermally injured patient journal, February 2004

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Temporal Cytokine Profiles in Severely Burned Patients: A Comparison of Adults and Children journal, June 2008

Comparison Between Civilian Burns and Combat Burns From Operation Iraqi Freedom and Operation Enduring Freedom journal, January 2006

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Comparison of Combat and Non-Combat Burns From Ongoing U.S. Military Operations journal, May 2006

Population differences in proinflammatory biology: Japanese have healthier profiles than Americans journal, March 2011

Biofilms in chronic wounds journal, January 2008

Increased Susceptibility to Infection Related to Extent of Burn Injury journal, February 1984

Role of Fibronectin in Diagnosing Bacterial Infection in Infancy journal, August 1988

ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival journal, January 2012

Changes in the Levels of Interleukins 6, 8, and 10, Tumor Necrosis Factor Alpha, and Granulocyte-colony Stimulating Factor in Korean Burn Patients: Relation to Burn Size and Postburn Time journal, January 2012

Infections in a burn intensive care unit: experience of seven years journal, January 2003

Circulating Fibronectin Depletion in Burned Patients: Relationship to Development of Infection and Prognostic Value journal, January 1985

Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. journal, February 1995

Topical Silver Treatment After Escharectomy of Infected Full Thickness Burn Wounds in Rats journal, January 2005

Regulatory T cell activity is partly inhibited in a mouse model of chronic Pseudomonas aeruginosa lung infection journal, October 2014

Compromised Host Defense on Pseudomonas aeruginosa Biofilms: Characterization of Neutrophil and Biofilm Interactions journal, October 2003

Genome Sequence of a Virulent Pseudomonas aeruginosa Strain, 12-4-4(59), Isolated from the Blood Culture of a Burn Patient journal, March 2016

Damage-associated molecular patterns (DAMPs) released after burn are associated with inflammation and monocyte activation journal, March 2017

Burn Trauma Induces Early Hmgb1 Release in Patients: its Correlation with Cytokines journal, January 2010

Opsonic Glycoprotein (Plasma Fibronectin) Levels after Burn Injury Relationship to Extent of Burn and Development of Sepsis journal, January 1980

Threshold age and burn size associated with poor outcomes in the elderly after burn injury journal, March 2016

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation journal, July 2002

Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection journal, July 2014

Surface Infection with Pseudomonas Aeruginosa journal, January 1964

Multiple Organ Failure as a Cause of Death in Patients With Severe Burns journal, January 2012

Why chronic wounds will not heal: a novel hypothesis journal, January 2008

Plasma fibronectin synthesis in normal and injured humans as determined by stable isotope incorporation. journal, October 1989

Inflammation: A Double-Edged Sword in the Response to Pseudomonas aeruginosa Infection journal, January 2017

Alterations of acute phase reaction and cytokine production in patients following severe burn injury journal, September 2002

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journal, February 2010

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds
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Pseudomonas aeruginosa Induces Localized Immunosuppression during Pneumonia
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Formation of Pseudomonas aeruginosa Biofilms in Full-thickness Scald Burn Wounds in Rats
journal, September 2019

Association of high mobility group box-1 protein levels with sepsis and outcome of severely burned patients
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Burn wounds infected with Pseudomonas aeruginosa triggers weight loss in rats
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Nonrandom Distribution of Pseudomonas aeruginosa and Staphylococcus aureus in Chronic Wounds
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Marked increase of plasma hyaluronan after major thermal injury and infusion therapy
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Changes in plasma fibronectin levels in burn patients
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Calculation of a new Meeh constant and experimental determination of burn size
journal, December 1996

Circulating fibronectin in burned patients
journal, July 1983

Modeling trauma in rats: similarities to humans and potential pitfalls to consider
journal, September 2019

The Effects of Infection of Thermal Injury by Pseudomonas Aeruginosa pao1 on the Murine Cytokine Response
journal, November 2001

Infections Caused by Pseudomonas aeruginosa
journal, March 1983

Sepsis in the burn patient: a different problem than sepsis in the general population
journal, August 2017

Treatment before transfer: the patient with burns
journal, September 2001

Burn size determines the inflammatory and hypermetabolic response
journal, January 2007

Pseudomonas infections in the thermally injured patient
journal, February 2004

Development of Pseudomonas aeruginosa Biofilms in Partial-Thickness Burn Wounds Using a Sprague-Dawley Rat Model
journal, August 2018

Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2
journal, July 2006

Animal models in burn research
journal, April 2014

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent
journal, February 2005

Burn Wound Infections
journal, April 2006

Temporal Cytokine Profiles in Severely Burned Patients: A Comparison of Adults and Children
journal, June 2008

Comparison Between Civilian Burns and Combat Burns From Operation Iraqi Freedom and Operation Enduring Freedom
journal, January 2006

Predicting and managing sepsis in burn patients: current perspectives
journal, January 2017

Early clinical complete blood count changes in severe burn injuries
journal, February 2019

Comparison of Combat and Non-Combat Burns From Ongoing U.S. Military Operations
journal, May 2006

Population differences in proinflammatory biology: Japanese have healthier profiles than Americans
journal, March 2011

Biofilms in chronic wounds
journal, January 2008

Increased Susceptibility to Infection Related to Extent of Burn Injury
journal, February 1984

Role of Fibronectin in Diagnosing Bacterial Infection in Infancy
journal, August 1988

ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival
journal, January 2012

Changes in the Levels of Interleukins 6, 8, and 10, Tumor Necrosis Factor Alpha, and Granulocyte-colony Stimulating Factor in Korean Burn Patients: Relation to Burn Size and Postburn Time
journal, January 2012

Infections in a burn intensive care unit: experience of seven years
journal, January 2003

Circulating Fibronectin Depletion in Burned Patients: Relationship to Development of Infection and Prognostic Value
journal, January 1985

Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo.
journal, February 1995

Topical Silver Treatment After Escharectomy of Infected Full Thickness Burn Wounds in Rats
journal, January 2005

Regulatory T cell activity is partly inhibited in a mouse model of chronic Pseudomonas aeruginosa lung infection
journal, October 2014

Compromised Host Defense on Pseudomonas aeruginosa Biofilms: Characterization of Neutrophil and Biofilm Interactions
journal, October 2003

Genome Sequence of a Virulent Pseudomonas aeruginosa Strain, 12-4-4(59), Isolated from the Blood Culture of a Burn Patient
journal, March 2016

Damage-associated molecular patterns (DAMPs) released after burn are associated with inflammation and monocyte activation
journal, March 2017

Burn Trauma Induces Early Hmgb1 Release in Patients: its Correlation with Cytokines
journal, January 2010

Opsonic Glycoprotein (Plasma Fibronectin) Levels after Burn Injury Relationship to Extent of Burn and Development of Sepsis
journal, January 1980

Threshold age and burn size associated with poor outcomes in the elderly after burn injury
journal, March 2016

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
journal, July 2002

Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection
journal, July 2014

Surface Infection with Pseudomonas Aeruginosa
journal, January 1964

Multiple Organ Failure as a Cause of Death in Patients With Severe Burns
journal, January 2012

Why chronic wounds will not heal: a novel hypothesis
journal, January 2008

Plasma fibronectin synthesis in normal and injured humans as determined by stable isotope incorporation.
journal, October 1989

Inflammation: A Double-Edged Sword in the Response to Pseudomonas aeruginosa Infection
journal, January 2017

Alterations of acute phase reaction and cytokine production in patients following severe burn injury
journal, September 2002

Cytokine Expression Profile over time in Severely Burned Pediatric Patients
journal, January 2006