skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer

Authors:
; ; ; ORCiD logo; ; ; ; ; ; ORCiD logo; ; ; ; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1581861
Grant/Contract Number:  
Laboratory Directed Research and Development (LDRD), contract number DEAC05-00OR22725; Lyceum Foundation Scholarship
Resource Type:
Published Article
Journal Name:
PLoS ONE
Additional Journal Information:
Journal Name: PLoS ONE Journal Volume: 15 Journal Issue: 1; Journal ID: ISSN 1932-6203
Publisher:
Public Library of Science (PLoS)
Country of Publication:
United States
Language:
English

Citation Formats

Miao, Ruizhong, Badger, Taylor C., Groesch, Kathleen, Diaz-Sylvester, Paula L., Wilson, Teresa, Ghareeb, Allen, Martin, Jongjin Anne, Cregger, Melissa, Welge, Michael, Bushell, Colleen, Auvil, Loretta, Zhu, Ruoqing, Brard, Laurent, Braundmeier-Fleming, Andrea, and Laganà, ed., Antonio Simone. Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer. United States: N. p., 2020. Web. doi:10.1371/journal.pone.0227707.
Miao, Ruizhong, Badger, Taylor C., Groesch, Kathleen, Diaz-Sylvester, Paula L., Wilson, Teresa, Ghareeb, Allen, Martin, Jongjin Anne, Cregger, Melissa, Welge, Michael, Bushell, Colleen, Auvil, Loretta, Zhu, Ruoqing, Brard, Laurent, Braundmeier-Fleming, Andrea, & Laganà, ed., Antonio Simone. Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer. United States. doi:10.1371/journal.pone.0227707.
Miao, Ruizhong, Badger, Taylor C., Groesch, Kathleen, Diaz-Sylvester, Paula L., Wilson, Teresa, Ghareeb, Allen, Martin, Jongjin Anne, Cregger, Melissa, Welge, Michael, Bushell, Colleen, Auvil, Loretta, Zhu, Ruoqing, Brard, Laurent, Braundmeier-Fleming, Andrea, and Laganà, ed., Antonio Simone. Thu . "Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer". United States. doi:10.1371/journal.pone.0227707.
@article{osti_1581861,
title = {Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer},
author = {Miao, Ruizhong and Badger, Taylor C. and Groesch, Kathleen and Diaz-Sylvester, Paula L. and Wilson, Teresa and Ghareeb, Allen and Martin, Jongjin Anne and Cregger, Melissa and Welge, Michael and Bushell, Colleen and Auvil, Loretta and Zhu, Ruoqing and Brard, Laurent and Braundmeier-Fleming, Andrea and Laganà, ed., Antonio Simone},
abstractNote = {},
doi = {10.1371/journal.pone.0227707},
journal = {PLoS ONE},
number = 1,
volume = 15,
place = {United States},
year = {2020},
month = {1}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1371/journal.pone.0227707

Save / Share:

Works referenced in this record:

Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation
journal, July 2014

  • Africa, Charlene; Nel, Janske; Stemmet, Megan
  • International Journal of Environmental Research and Public Health, Vol. 11, Issue 7
  • DOI: 10.3390/ijerph110706979

Diagnosis of ruptured ectopic pregnancy with peritoneal lavage
journal, October 1982


Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A prospective pilot study
journal, April 2018

  • Duarte, S. M. B.; Stefano, J. T.; Miele, L.
  • Nutrition, Metabolism and Cardiovascular Diseases, Vol. 28, Issue 4
  • DOI: 10.1016/j.numecd.2017.10.014

Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases
journal, October 2015

  • Paul, Bidisha; Barnes, Stephen; Demark-Wahnefried, Wendy
  • Clinical Epigenetics, Vol. 7, Issue 1
  • DOI: 10.1186/s13148-015-0144-7

Case for a role of the microbiome in gynecologic cancers: Clinician's perspective: Role of the microbiome in gynecologic cancers
journal, August 2018

  • Mert, Ismail; Walther-Antonio, Marina; Mariani, Andrea
  • Journal of Obstetrics and Gynaecology Research, Vol. 44, Issue 9
  • DOI: 10.1111/jog.13701

Interactions Between the Intestinal Microbiome and Liver Diseases
journal, May 2014


The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass
journal, February 2008


Sonographic detection of echogenic fluid and correlation with culdocentesis in the evaluation of ectopic pregnancy.
journal, May 1998

  • Chen, P. C.; Sickler, G. K.; Dubinsky, T. J.
  • American Journal of Roentgenology, Vol. 170, Issue 5
  • DOI: 10.2214/ajr.170.5.9574606

The Intestinal Microbiome in Early Life: Health and Disease
journal, September 2014

  • Arrieta, Marie-Claire; Stiemsma, Leah T.; Amenyogbe, Nelly
  • Frontiers in Immunology, Vol. 5
  • DOI: 10.3389/fimmu.2014.00427

Stool Microbiota at Neutrophil Recovery Is Predictive for Severe Acute Graft vs Host Disease After Hematopoietic Cell Transplantation
journal, August 2017

  • Golob, Jonathan L.; Pergam, Steven A.; Srinivasan, Sujatha
  • Clinical Infectious Diseases, Vol. 65, Issue 12
  • DOI: 10.1093/cid/cix699

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
journal, November 2017

  • Routy, Bertrand; Le Chatelier, Emmanuelle; Derosa, Lisa
  • Science, Vol. 359, Issue 6371
  • DOI: 10.1126/science.aan3706

The early detection of ovarian cancer: from traditional methods to proteomics. Can we really do better than serum CA-125?
journal, September 2008

  • Nossov, Vladimir; Amneus, Malaika; Su, Feng
  • American Journal of Obstetrics and Gynecology, Vol. 199, Issue 3
  • DOI: 10.1016/j.ajog.2008.04.009

Evaluation of ovarian cancer biomarkers HE4 and CA-125 in women presenting with a suspicious cystic ovarian mass
journal, January 2011

  • Partheen, Karolina; Kristjansdottir, Björg; Sundfeldt, Karin
  • Journal of Gynecologic Oncology, Vol. 22, Issue 4
  • DOI: 10.3802/jgo.2011.22.4.244

Gut microbiota, metabolites and host immunity
journal, May 2016

  • Rooks, Michelle G.; Garrett, Wendy S.
  • Nature Reviews Immunology, Vol. 16, Issue 6
  • DOI: 10.1038/nri.2016.42

The microbiome and rheumatoid arthritis
journal, August 2011


Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment
journal, June 2018


A Review and Tutorial of Machine Learning Methods for Microbiome Host Trait Prediction
journal, June 2019


Irritable bowel syndrome: a gut microbiota-related disorder?
journal, January 2017

  • Bhattarai, Yogesh; Muniz Pedrogo, David A.; Kashyap, Purna C.
  • American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 312, Issue 1
  • DOI: 10.1152/ajpgi.00338.2016

Regression shrinkage and selection via the lasso: a retrospective: Regression Shrinkage and Selection via the Lasso
journal, April 2011


Ovarian cancer screening—ultrasound; impact on ovarian cancer mortality
journal, October 2018

  • Kamal, Rasha; Hamed, Soha; Mansour, Sahar
  • The British Journal of Radiology, Vol. 91, Issue 1090
  • DOI: 10.1259/bjr.20170571

Imaging and Differential Diagnosis of Ovarian Cancer
journal, August 2019


Prediction error estimation: a comparison of resampling methods
journal, May 2005


Blowing on Embers: Commensal Microbiota and Our Immune System
journal, July 2014


Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
journal, November 2013


Gut microbes as future therapeutics in treating inflammatory and infectious diseases: Lessons from recent findings
journal, November 2018

  • Mukherjee, Suprabhat; Joardar, Nikhilesh; Sengupta, Subhasree
  • The Journal of Nutritional Biochemistry, Vol. 61
  • DOI: 10.1016/j.jnutbio.2018.07.010

Search and clustering orders of magnitude faster than BLAST
journal, August 2010


Defining dysbiosis and its influence on host immunity and disease: How changes in microbiota structure influence health
journal, June 2014

  • Petersen, Charisse; Round, June L.
  • Cellular Microbiology, Vol. 16, Issue 7
  • DOI: 10.1111/cmi.12308

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
journal, January 2010


Variable selection using random forests
journal, October 2010

  • Genuer, Robin; Poggi, Jean-Michel; Tuleau-Malot, Christine
  • Pattern Recognition Letters, Vol. 31, Issue 14
  • DOI: 10.1016/j.patrec.2010.03.014

Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohnʼs Disease
journal, January 2016


The role of the vaginal microbiome in gynaecological cancer
journal, April 2017

  • Champer, M.; Wong, Am; Champer, J.
  • BJOG: An International Journal of Obstetrics & Gynaecology, Vol. 125, Issue 3
  • DOI: 10.1111/1471-0528.14631

CA-125 concentration in serum and peritoneal fluid in patients with endometriosis – preliminary results
journal, January 2012

  • Szubert, Maria; Suzin, Jacek; Wierzbowski, Tomasz
  • Archives of Medical Science, Vol. 3
  • DOI: 10.5114/aoms.2012.29529

HE4 in the differential diagnosis of ovarian masses
journal, June 2015


The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes
journal, March 2011


On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other
journal, March 1947


Dietary modulation of the microbiome affects autoinflammatory disease
journal, September 2014

  • Lukens, John R.; Gurung, Prajwal; Vogel, Peter
  • Nature, Vol. 516, Issue 7530
  • DOI: 10.1038/nature13788

Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer
journal, March 2010


Unraveling a difficult diagnosis: the tricks for early recognition of ovarian cancer
journal, July 2019


Screening for Ovarian Cancer: US Preventive Services Task Force Recommendation Statement
journal, February 2018


Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma
journal, March 2019


The role of the microbiome in cancer development and therapy: Microbiome and Cancer
journal, May 2017

  • Bhatt, Aadra P.; Redinbo, Matthew R.; Bultman, Scott J.
  • CA: A Cancer Journal for Clinicians, Vol. 67, Issue 4
  • DOI: 10.3322/caac.21398

CA 125 in peritoneal fluid and serum from patients with benign gynecologic conditions and ovarian cancer
journal, February 1990


HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm
journal, February 2011

  • Van Gorp, T.; Cadron, I.; Despierre, E.
  • British Journal of Cancer, Vol. 104, Issue 5
  • DOI: 10.1038/sj.bjc.6606092

The Biological Observation Matrix (BIOM) format or: how I learned to stop worrying and love the ome-ome
journal, July 2012

  • McDonald, Daniel; Clemente, Jose C.; Kuczynski, Justin
  • GigaScience, Vol. 1, Issue 1
  • DOI: 10.1186/2047-217X-1-7

Insights into the Role of Erysipelotrichaceae in the Human Host
journal, November 2015


QIIME allows analysis of high-throughput community sequencing data
journal, April 2010

  • Caporaso, J. Gregory; Kuczynski, Justin; Stombaugh, Jesse
  • Nature Methods, Vol. 7, Issue 5
  • DOI: 10.1038/nmeth.f.303

Galaxy: A platform for interactive large-scale genome analysis
journal, September 2005


Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation
journal, December 2014

  • Gregory, Jill C.; Buffa, Jennifer A.; Org, Elin
  • Journal of Biological Chemistry, Vol. 290, Issue 9
  • DOI: 10.1074/jbc.M114.618249

Phylogenomics and signature proteins for the alpha Proteobacteria and its main groups
journal, January 2007


The gut microbiome, symptoms, and targeted interventions in children with cancer: a systematic review
journal, November 2017

  • Bai, Jinbing; Behera, Madhusmita; Bruner, Deborah Watkins
  • Supportive Care in Cancer, Vol. 26, Issue 2
  • DOI: 10.1007/s00520-017-3982-3

Leveraging sequence-based faecal microbial community survey data to identify a composite biomarker for colorectal cancer
journal, March 2017


Discovery of a Novel Seminal Fluid Microbiome and Influence of Estrogen Receptor Alpha Genetic Status
journal, March 2016

  • Javurek, Angela B.; Spollen, William G.; Ali, Amber M. Mann
  • Scientific Reports, Vol. 6, Issue 1
  • DOI: 10.1038/srep23027

Complete genome sequence of Odoribacter splanchnicus type strain (1651/6T)
journal, April 2011

  • Göker, Markus; Gronow, Sabine; Zeytun, Ahmet
  • Standards in Genomic Sciences, Vol. 4, Issue 2
  • DOI: 10.4056/sigs.1714269

Microbiota: a key orchestrator of cancer therapy
journal, March 2017

  • Roy, Soumen; Trinchieri, Giorgio
  • Nature Reviews Cancer, Vol. 17, Issue 5
  • DOI: 10.1038/nrc.2017.13

Mediterranean Diet and Health: Food Effects on Gut Microbiota and Disease Control
journal, July 2014

  • Del Chierico, Federica; Vernocchi, Pamela; Dallapiccola, Bruno
  • International Journal of Molecular Sciences, Vol. 15, Issue 7
  • DOI: 10.3390/ijms150711678

Diagnostic value of derived neutrophil‐to‐lymphocyte ratio in patients with ovarian cancer
journal, January 2019

  • Wu, Yang‐yang; Qin, Yuan‐yuan; Qin, Jin‐qiu
  • Journal of Clinical Laboratory Analysis, Vol. 33, Issue 4
  • DOI: 10.1002/jcla.22833

Measuring and testing dependence by correlation of distances
journal, December 2007

  • Székely, Gábor J.; Rizzo, Maria L.; Bakirov, Nail K.
  • The Annals of Statistics, Vol. 35, Issue 6
  • DOI: 10.1214/009053607000000505

Regularization Paths for Generalized Linear Models via Coordinate Descent
journal, January 2010

  • Friedman, Jerome; Hastie, Trevor; Tibshirani, Robert
  • Journal of Statistical Software, Vol. 33, Issue 1
  • DOI: 10.18637/jss.v033.i01

Immune System and DNA Repair Defects in Ovarian Cancer: Implications for Locoregional Approaches
journal, May 2019

  • Farolfi, Alberto; Gurioli, Giorgia; Fugazzola, Paola
  • International Journal of Molecular Sciences, Vol. 20, Issue 10
  • DOI: 10.3390/ijms20102569

The vaginal and gastrointestinal microbiomes in gynecologic cancers: A review of applications in etiology, symptoms and treatment
journal, July 2015


The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead
journal, May 2014


Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
journal, March 2012

  • Caporaso, J. Gregory; Lauber, Christian L.; Walters, William A.
  • The ISME Journal, Vol. 6, Issue 8
  • DOI: 10.1038/ismej.2012.8

Evaluation of the antimicrobial effect of lactoferrin on Porphyromonas gingivalis , Prevotella intermedia and Prevotella nigrescens
journal, May 1998


Increased Systolic and Diastolic Blood Pressure Is Associated With Altered Gut Microbiota Composition and Butyrate Production in Early Pregnancy
journal, October 2016


Feasibility and surgical outcomes of conventional and robot-assisted laparoscopy for early-stage ovarian cancer: a retrospective, multicenter analysis
journal, April 2016

  • Bellia, Adriano; Vitale, Salvatore Giovanni; Laganà, Antonio Simone
  • Archives of Gynecology and Obstetrics, Vol. 294, Issue 3
  • DOI: 10.1007/s00404-016-4087-9

Random Forests
journal, January 2001


HE4 tumor marker concentration in neoplastic peritoneal effusion and in peritoneal fluid associated with benign gynecological diseases
journal, January 2014

  • Chudecka-Głaz, Anita; Cymbaluk-Płoska, Aneta; Menkiszak, Janusz
  • Journal of Ovarian Research, Vol. 7, Issue 1
  • DOI: 10.1186/1757-2215-7-22

Comprehensive Serum Profiling for the Discovery of Epithelial Ovarian Cancer Biomarkers
journal, December 2011


Robotic Surgery in Women With Ovarian Cancer: Surgical Technique and Evidence of Clinical Outcomes
journal, March 2016

  • Minig, Lucas; Padilla Iserte, Pablo; Zorrero, Cristina
  • Journal of Minimally Invasive Gynecology, Vol. 23, Issue 3
  • DOI: 10.1016/j.jmig.2015.10.014