Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils

doi:10.1002/cphc.201901053

This content will become publicly available on January 8, 2021

Title: Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils

Authors:

^[1]; Ostrovsky, Dmitry ^[2]; Fu, Riqiang ^[3]

Department of ChemistryUniversity of Colorado Denver Denver CO 80204 USA
Department of MathematicsUniversity of Colorado Denver Denver CO 80204 USA
National High Field Magnetic Laboratory Tallahassee FL 32310 USA

Publication Date:: 2020-01-09

Sponsoring Org.:: USDOE

OSTI Identifier:: 1581839

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: ChemPhysChem

Additional Journal Information:: Journal Name: ChemPhysChem; Journal ID: ISSN 1439-4235

Publisher:: Wiley Blackwell (John Wiley & Sons)

Country of Publication:: Germany

Language:: English

Citation Formats


                    Vugmeyster, Liliya, Ostrovsky, Dmitry, and Fu, Riqiang. Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils.  Germany: N. p., 2020. 
        Web.  doi:10.1002/cphc.201901053.

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                    Vugmeyster, Liliya, Ostrovsky, Dmitry, & Fu, Riqiang. Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils.  Germany.  doi:10.1002/cphc.201901053.

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                    Vugmeyster, Liliya, Ostrovsky, Dmitry, and Fu, Riqiang. Thu .  
        "Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils".  Germany.  doi:10.1002/cphc.201901053.

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@article{osti_1581839,

  title        = {Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils},

  author       = {Vugmeyster, Liliya and Ostrovsky, Dmitry and Fu, Riqiang},

  abstractNote = {},

  doi          = {10.1002/cphc.201901053},

  journal      = {ChemPhysChem},

  number       = ,

  volume       = ,

  place        = {Germany},

  year         = {2020},

  month        = {1}

}

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This content will become publicly available on January 8, 2021

Title: Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q‐CEST) Solid‐State NMR for Static Powder Samples: Approach and Applications to Amyloid‐β Fibrils

Citation Formats

Using low-E resonators to reduce RF heating in biological samples for static solid-state NMR up to 900MHz journal, March 2007

A Simple Mesh Generator in MATLAB journal, January 2004

Rotational echo 14 N/ 13 C/ 1 H triple resonance solid‐state nuclear magnetic resonance: A probe of 13 C– 14 N internuclear distances journal, May 1993

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's -Amyloid Fibrils journal, January 2005

Experimental Constraints on Quaternary Structure in Alzheimer's β-Amyloid Fibrils † journal, January 2006

Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR journal, October 2011

Protein–ice interaction of an antifreeze protein observed with solid-state NMR journal, September 2010

Direct Determination of Motional Correlation Times by 1D MAS and 2D Exchange NMR Techniques journal, October 1998

Solid‐state dynamic processes in complex systems analyzed by two‐dimensional isotropic–anisotropic correlation nuclear magnetic resonance journal, July 1994

The Principles of Nuclear Magnetism journal, December 1961

The Unique Alzheimer’s β-Amyloid Triangular Fibril Has a Cavity along the Fibril Axis under Physiological Conditions journal, March 2011

The Scaling and Squaring Method for the Matrix Exponential Revisited journal, January 2005

Reaction Rates by Nuclear Magnetic Resonance journal, March 1958

Slow Motions in the Hydrophobic Core of Chicken Villin Headpiece Subdomain and Their Contributions to Configurational Entropy and Heat Capacity from Solid-State Deuteron NMR Measurements journal, December 2011

Spin-locking of half-integer quadrupolar nuclei in NMR of solids: The far off-resonance case journal, July 2017

Deuterium Rotating Frame NMR Relaxation Measurements in the Solid State under Static Conditions for Quantification of Dynamics journal, August 2018

The relaxation dynamics of spin I =1 nuclei with a static quadrupolar coupling and a radio‐frequency field journal, October 1993

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Fast Motions of Key Methyl Groups in Amyloid-β Fibrils journal, November 2016

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Microsecond Time Scale Proton Rotating-Frame Relaxation under Magic Angle Spinning journal, June 2017

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Spin-locking of half-integer quadrupolar nuclei in nuclear magnetic resonance of solids: Creation and evolution of coherences journal, February 2004

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Flexibility and Solvation of Amyloid-β Hydrophobic Core journal, July 2016

Studying dynamics by magic-angle spinning solid-state NMR spectroscopy: Principles and applications to biomolecules journal, August 2016

Using low-E resonators to reduce RF heating in biological samples for static solid-state NMR up to 900MHz
journal, March 2007

A Simple Mesh Generator in MATLAB
journal, January 2004

Rotational echo ¹⁴ N/ ¹³ C/ ¹ H triple resonance solid‐state nuclear magnetic resonance: A probe of ¹³ C– ¹⁴ N internuclear distances
journal, May 1993

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's -Amyloid Fibrils
journal, January 2005

Experimental Constraints on Quaternary Structure in Alzheimer's β-Amyloid Fibrils ^†
journal, January 2006

Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
journal, October 2011

Protein–ice interaction of an antifreeze protein observed with solid-state NMR
journal, September 2010

Direct Determination of Motional Correlation Times by 1D MAS and 2D Exchange NMR Techniques
journal, October 1998

Solid‐state dynamic processes in complex systems analyzed by two‐dimensional isotropic–anisotropic correlation nuclear magnetic resonance
journal, July 1994

The Principles of Nuclear Magnetism
journal, December 1961

The Unique Alzheimer’s β-Amyloid Triangular Fibril Has a Cavity along the Fibril Axis under Physiological Conditions
journal, March 2011

The Scaling and Squaring Method for the Matrix Exponential Revisited
journal, January 2005

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journal, March 1958

Slow Motions in the Hydrophobic Core of Chicken Villin Headpiece Subdomain and Their Contributions to Configurational Entropy and Heat Capacity from Solid-State Deuteron NMR Measurements
journal, December 2011

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journal, July 2017

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journal, August 2018

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journal, October 1993

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils
journal, November 2008

SWISS-MODEL and the Swiss-Pdb Viewer: An environment for comparative protein modeling
journal, January 1997

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journal, September 2009

Measurement of Proton Chemical Shifts in Invisible States of Slowly Exchanging Protein Systems by Chemical Exchange Saturation Transfer
journal, November 2012

Fast Motions of Key Methyl Groups in Amyloid-β Fibrils
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journal, June 2017

Fiber Diffraction Data Indicate a Hollow Core for the Alzheimer's Aβ 3-Fold Symmetric Fibril
journal, October 2012

MAS NMR spin locking of half-integer quadrupolar nuclei
journal, January 1992

ODESSA, a New 1D NMR Exchange Experiment for Chemically Equivalent Nuclei in Rotating Solids
journal, November 1996

Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation
journal, April 2012

Chemical exchange in biomacromolecules: Past, present, and future
journal, April 2014

Selective inversion investigations of slow molecular motion in solid state deuteron NMR spectroscopy
journal, April 1996

Deuterium quadrupole-echo NMR spectroscopy. III. Practical aspects of lineshape calculations for multiaxis rotational processes
journal, March 1987

Spin-locking of half-integer quadrupolar nuclei in nuclear magnetic resonance of solids: Creation and evolution of coherences
journal, February 2004

Seeded growth of -amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure
journal, April 2009

Effects of jump dynamics on solid state nuclear magnetic resonance line shapes and spin relaxation times
journal, May 2009

Flexibility and Solvation of Amyloid-β Hydrophobic Core
journal, July 2016

Studying dynamics by magic-angle spinning solid-state NMR spectroscopy: Principles and applications to biomolecules
journal, August 2016