Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides

Zhang, Chuanliang; Li, Xinlu; Song, Dunlun; Ling, Yun; Zhou, Yuanlin; Yang, Xinling

doi:10.1002/ps.5721

Title: Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides

Authors:

Zhang, Chuanliang ^[1]; Li, Xinlu ^[1]; Song, Dunlun ^[2]; Ling, Yun ^[1]; Zhou, Yuanlin ^[1];

^[1]

Department of Applied Chemistry College of Science, China Agricultural University Beijing P. R. China
Department of Entomology College of Plant Protection, China Agricultural University Beijing P. R. China

Publication Date:: 2020-01-06

Sponsoring Org.:: USDOE

OSTI Identifier:: 1581203

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Pest Management Science

Additional Journal Information:: Journal Name: Pest Management Science Journal Volume: 76 Journal Issue: 10; Journal ID: ISSN 1526-498X

Publisher:: Wiley Blackwell (John Wiley & Sons)

Country of Publication:: United Kingdom

Language:: English

Citation Formats


                    Zhang, Chuanliang, Li, Xinlu, Song, Dunlun, Ling, Yun, Zhou, Yuanlin, and Yang, Xinling. Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides.  United Kingdom: N. p., 2020. 
Web.  doi:10.1002/ps.5721.

Copy to clipboard


                    Zhang, Chuanliang, Li, Xinlu, Song, Dunlun, Ling, Yun, Zhou, Yuanlin, & Yang, Xinling. Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides.  United Kingdom.  https://doi.org/10.1002/ps.5721

Copy to clipboard


                    Zhang, Chuanliang, Li, Xinlu, Song, Dunlun, Ling, Yun, Zhou, Yuanlin, and Yang, Xinling. Mon .  
"Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides".  United Kingdom.  https://doi.org/10.1002/ps.5721.

Copy to clipboard


                    
@article{osti_1581203,

  title        = {Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides},

  author       = {Zhang, Chuanliang and Li, Xinlu and Song, Dunlun and Ling, Yun and Zhou, Yuanlin and Yang, Xinling},

  abstractNote = {},

  doi          = {10.1002/ps.5721},

  journal      = {Pest Management Science},

  number       = 10,

  volume       = 76,

  place        = {United Kingdom},

  year         = {2020},

  month        = {1}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Accepted Manuscript (Publisher)

Publisher's Version of Record
https://doi.org/10.1002/ps.5721

Other availability

Search WorldCat to find libraries that may hold this journal

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Physiological effects of biostable kinin and CAPA analogs in the Chagas disease vector, Rhodnius prolixus
journal, November 2019

Sangha, Vishal; Nachman, Ronald J.; Lange, Angela
Insect Biochemistry and Molecular Biology, Vol. 114
DOI: 10.1016/j.ibmb.2019.103223

Peptidomimetic design
journal, January 1998

Ripka, Amy S.; Rich, Daniel H.
Current Opinion in Chemical Biology, Vol. 2, Issue 4
DOI: 10.1016/S1367-5931(98)80119-1

Effect of helicokinins and ACE inhibitors on water balance and development of Heliothis virescens larvae
journal, November 2000

Seinsche, A.; Dyker, H.; Lösel, P.
Journal of Insect Physiology, Vol. 46, Issue 11
DOI: 10.1016/S0022-1910(00)00065-2

Consensus chemistry and R-turn conformation of the active core of the insect kinin neuropeptide family
journal, January 1997

Roberts, Victoria A.; Nachman, Ronald J.; Coast, Geoff M.
Chemistry & Biology, Vol. 4, Issue 2
DOI: 10.1016/S1074-5521(97)90254-4

The Kinin Peptide Family in Invertebrates
journal, December 1999

Torfs, Pieter; Nieto, Julie; Veelaert, Dirk
Annals of the New York Academy of Sciences, Vol. 897, Issue 1 NEUROPEPTIDES
DOI: 10.1111/j.1749-6632.1999.tb07906.x

Design, synthesis and aphicidal activity of N-terminal modified insect kinin analogs
journal, June 2015

Zhang, Chuanliang; Qu, Yanyan; Wu, Xiaoqing
Peptides, Vol. 68
DOI: 10.1016/j.peptides.2014.07.028

β-amino acid analogs of an insect neuropeptide feature potent bioactivity and resistance to peptidase hydrolysis
journal, January 2007

Zubrzak, Pawel; Williams, Howard; Coast, Geoffrey M.
Biopolymers, Vol. 88, Issue 1
DOI: 10.1002/bip.20638

The endopeptidase activity and the activation by Cl− of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica
journal, March 1996

Lamango, Nazarius S.; Sajid, Mohammed; Isaac, R. Elwyn
Biochemical Journal, Vol. 314, Issue 2
DOI: 10.1042/bj3140639

Synthesis, Biological Activity, and Conformational Study of N-Methylated Allatostatin Analogues Inhibiting Juvenile Hormone Biosynthesis
journal, March 2015

Xie, Yong; Zhang, Li; Zhang, Chuanliang
Journal of Agricultural and Food Chemistry, Vol. 63, Issue 11
DOI: 10.1021/acs.jafc.5b00882

The mosquito Aedes aegypti (L.) leucokinin receptor is a multiligand receptor for the three Aedes kinins
journal, January 2005

Pietrantonio, P. V.; Jagge, C.; Taneja-Bageshwar, S.
Insect Molecular Biology, Vol. 14, Issue 1
DOI: 10.1111/j.1365-2583.2004.00531.x

Diuretic activity of C-terminal group analogues of the insect kinins in Acheta domesticus
journal, January 1995

Nachman, Ronald J.; Coast, Geoffrey M.; Holman, G. Mark
Peptides, Vol. 16, Issue 5
DOI: 10.1016/0196-9781(95)00047-N

Prediction of Tight Turns and Their Types in Proteins
journal, November 2000

Chou, Kuo-Chen
Analytical Biochemistry, Vol. 286, Issue 1
DOI: 10.1006/abio.2000.4757

Isolation, characterization and biological activity of a diuretic myokinin neuropeptide from the housefly, Musca domestica
journal, January 1999

Holman, G. Mark; Nachman, Ronald J.; Coast, Geoffrey M.
Peptides, Vol. 20, Issue 1
DOI: 10.1016/S0196-9781(98)00150-8

Inhibition of digestive enzyme release by neuropeptides in larvae of Opisina arenosella (Lepidoptera: Cryptophasidae)
journal, June 2002

Harshini, S.; Nachman, R. J.; Sreekumar, S.
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, Vol. 132, Issue 2
DOI: 10.1016/S1096-4959(02)00047-7

Identification of selective and non-selective, biostable β-amino acid agonists of recombinant insect kinin receptors from the southern cattle tick Boophilus microplus and mosquito Aedes aegypti
journal, February 2008

Taneja-Bageshwar, Suparna; Strey, Allison; Zubrzak, Pawel
Peptides, Vol. 29, Issue 2
DOI: 10.1016/j.peptides.2007.07.034

Potential of natural peptidic compounds as leads for novel pesticides
journal, January 1993

Bland, John M.; Edwards, J. Vince; Eaton, Scott R.
Pesticide Science, Vol. 39, Issue 4
DOI: 10.1002/ps.2780390414

Aib-Containing Analogues of the Insect Kinin Neuropeptide Family Demonstrate Resistance to an Insect Angiotensin-Converting Enzyme and Potent Diuretic Activity
journal, January 1997

Nachman,, Ronald J.; Isaac, R. Elwyn; Coast, Geoffrey M.
Peptides, Vol. 18, Issue 1
DOI: 10.1016/S0196-9781(96)00233-1

New reagents, reactions, and peptidomimetics for drug design
journal, January 2001

Goodman, Murray; Zapf, Christoph; Rew, Yosup
Biopolymers, Vol. 60, Issue 3
DOI: 10.1002/1097-0282(2001)60:3<229::AID-BIP10034>3.0.CO;2-P

A Method of Computing the Effectiveness of an Insecticide
journal, April 1925

Abbott, W. S.
Journal of Economic Entomology, Vol. 18, Issue 2
DOI: 10.1093/jee/18.2.265a

Enhanced in vivo activity of peptidase-resistant analogs of the insect kinin neuropeptide family
journal, April 2002

Nachman, Ronald J.; Strey, Allison; Isaac, Elwyn
Peptides, Vol. 23, Issue 4
DOI: 10.1016/S0196-9781(01)00654-4

cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation
journal, April 2002

Nachman, Ronald J.; Zabrocki, Janusz; Olczak, Jacek
Peptides, Vol. 23, Issue 4
DOI: 10.1016/S0196-9781(01)00651-9

Cloning and Expression of an Evolutionary Conserved Single-domain Angiotensin Converting Enzyme from Drosophila melanogaster
journal, June 1995

Cornell, Michael J.; Williams, Tracy A.; Lamango, Nazarius S.
Journal of Biological Chemistry, Vol. 270, Issue 23
DOI: 10.1074/jbc.270.23.13613

The diuretic activity of a series of cephalomyotropic neuropeptides, the achetakinins, on isolated Malpighian tubules of the house cricket, Acheta domesticus
journal, January 1990

Coast, Geoffrey M.; Holman, G. Mark; Nachman, Ronald J.
Journal of Insect Physiology, Vol. 36, Issue 7
DOI: 10.1016/0022-1910(90)90098-Z

Insect Neuropeptides
journal, January 1990

Holman, G. M.; Nachman, R. J.; Wright, M. S.
Annual Review of Entomology, Vol. 35, Issue 1
DOI: 10.1146/annurev.en.35.010190.001221

Functional analysis of a G protein-coupled receptor from the Southern cattle tick Boophilus microplus (Acari: Ixodidae) identifies it as the first arthropod myokinin receptor
journal, February 2003

Holmes, S. P.; Barhoumi, R.; Nachman, R. J.
Insect Molecular Biology, Vol. 12, Issue 1
DOI: 10.1046/j.1365-2583.2003.00384.x

Toward the Development of Novel Pest Management Agents Based upon Insect Kinin Neuropeptide Analogues
journal, April 2009

Nachman, Ronald J.; Pietrantonio, Patricia V.; Coast, Geoffrey M.
Annals of the New York Academy of Sciences, Vol. 1163, Issue 1
DOI: 10.1111/j.1749-6632.2008.03633.x

Biostable agonists that match or exceed activity of native insect kinins on recombinant arthropod GPCRs
journal, May 2009

Taneja-Bageshwar, Suparna; Strey, Allison; Isaac, R. Elwyn
General and Comparative Endocrinology, Vol. 162, Issue 1
DOI: 10.1016/j.ygcen.2008.10.013

β-Peptides: From Structure to Function
journal, October 2001

Cheng, Richard P.; Gellman, Samuel H.; DeGrado, William F.
Chemical Reviews, Vol. 101, Issue 10
DOI: 10.1021/cr000045i

Insect peptide hormones: a selective review of their physiology and potential application for pest control: Insect peptide hormones
journal, July 2003

Gäde, Gerd; Goldsworthy, Graham J.
Pest Management Science, Vol. 59, Issue 10
DOI: 10.1002/ps.755

Antifeedant activity and high mortality in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae) induced by biostable insect kinin analogs
journal, March 2010

Smagghe, Guy; Mahdian, Kamran; Zubrzak, Pawel
Peptides, Vol. 31, Issue 3
DOI: 10.1016/j.peptides.2009.07.001

A worldwide survey of neonicotinoids in honey
journal, October 2017

Mitchell, E. A. D.; Mulhauser, B.; Mulot, M.
Science, Vol. 358, Issue 6359
DOI: 10.1126/science.aan3684

Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid ( Myzus persicae and Macrosiphum rosae ) stress tolerance
journal, February 2019

Alford, Lucy; Marley, Richard; Dornan, Anthony
Pest Management Science, Vol. 75, Issue 6
DOI: 10.1002/ps.5372

Biostable insect kinin analogs reduce blood meal and disrupt ecdysis in the blood-gorging Chagas’ disease vector, Rhodnius prolixus
journal, June 2016

Lange, Angela B.; Nachman, Ronald J.; Kaczmarek, Krzysztof
Peptides, Vol. 80
DOI: 10.1016/j.peptides.2016.01.012

Eco-Friendly Insecticide Discovery via Peptidomimetics: Design, Synthesis, and Aphicidal Activity of Novel Insect Kinin Analogues
journal, May 2015

Zhang, Chuanliang; Qu, Yanyan; Wu, Xiaoqing
Journal of Agricultural and Food Chemistry, Vol. 63, Issue 18
DOI: 10.1021/acs.jafc.5b01225

Evaluation of Aib and PEG-polymer insect kinin analogs on mosquito and tick GPCRs identifies potent new pest management tools with potentially enhanced biostability and bioavailability
journal, July 2019

Xiong, Caixing; Kaczmarek, Krzysztof; Zabrocki, Janusz
General and Comparative Endocrinology, Vol. 278
DOI: 10.1016/j.ygcen.2018.08.002

Primary structure and synthesis of a blocked myotropic neuropeptide isolated from the cockroach, Leucophaea maderae
journal, January 1986

Holman, G. M.; Cook, B. J.; Nachman, R. J.
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, Vol. 85, Issue 1
DOI: 10.1016/0742-8413(86)90077-0

Hydrolysis of Insect Neuropeptides by an Angiotensin-Converting Enzyme From the Housefly, Musca domestica
journal, January 1997

Lamango, N. S.; Nachman, R. J.; Hayes, T. K.
Peptides, Vol. 18, Issue 1
DOI: 10.1016/S0196-9781(96)00232-X

A C-terminal aldehyde insect kinin analog enhances inhibition of weight gain and induces significant mortality in Helicoverpa zea larvae
journal, October 2003

Nachman, Ronald J.; Coast, Geoffrey M.; Douat, Céline
Peptides, Vol. 24, Issue 10
DOI: 10.1016/j.peptides.2003.06.008

Comparative structure-activity analysis of insect kinin core analogs on recombinant kinin receptors from Southern cattle tickBoophilus microplus (Acari: Ixodidae) and mosquitoAedes aegypti (Diptera: Culicidae)
journal, January 2006

Taneja-Bageshwar, Suparna; Strey, Allison; Zubrzak, Pawel
Archives of Insect Biochemistry and Physiology, Vol. 62, Issue 3
DOI: 10.1002/arch.20129

Peptidomimetics, a synthetic tool of drug discovery
journal, June 2008

Vagner, Josef; Qu, Hongchang; Hruby, Victor J.
Current Opinion in Chemical Biology, Vol. 12, Issue 3
DOI: 10.1016/j.cbpa.2008.03.009

Peptidomimetic therapeutics: scientific approaches and opportunities
journal, February 2017

Qvit, Nir; Rubin, Samuel J. S.; Urban, Travis J.
Drug Discovery Today, Vol. 22, Issue 2
DOI: 10.1016/j.drudis.2016.11.003

Advances in the application of neuropeptides in insect control
journal, September 2000

Altstein, Miriam; Ben-Aziz, Orna; Schefler, Irit
Crop Protection, Vol. 19, Issue 8-10
DOI: 10.1016/S0261-2194(00)00071-5

Similar Records in DOE PAGES and OSTI.GOV collections:

Disabled insecticidal proteins: A novel tool to understand differences in insect receptor utilization

Journal Article Jerga, Agoston ; Evdokimov, Artem G. ; Moshiri, Farhad ; ... - Insect Biochemistry and Molecular Biology
https://doi.org/10.1016/j.ibmb.2018.12.006
Characterization and property investigation of novel eco‐friendly agar/carrageenan/TiO ₂ nanocomposite films

Journal Article Hou, X. ; Xue, Z. ; Liu, J. ; ... - Journal of Applied Polymer Science
https://doi.org/10.1002/app.47113
Rapid and eco-friendly synthesis of copper nanoparticles

Journal Article Suresh, Y., E-mail: sap-bak@yahoo.com ; Annapurna, S., E-mail: sap-bak@yahoo.com ; Bhikshamaiah, G., E-mail: sap-bak@yahoo.com ; ... - AIP Conference Proceedings

Copper nanoparticles were synthesized successfully through chemical reduction method stabilized by PVA along with different stabilizers namely, Kondagogu (Cochlospermum gossypium), Maida Flour and Starch. The resulting copper nanoparticles were characterized by X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR) Spectroscopy and Scanning Electron Microscopy (SEM) experiments to study the size and shape of the particles and functional group of the stabilizing agent. The particle sizes were confirmed by Small Angle X-ray Scattering (SAXS) experiment and are found to be around 6.5 nm.
https://doi.org/10.1063/1.4872606
Eco-friendly fly ash utilization: potential for land application

Journal Article Malik, A ; Thapliyal, A - Critical Reviews in Environmental Science and Technology

The increase in demand for power in domestic, agricultural, and industrial sectors has increased the pressure on coal combustion and aggravated the problem of fly ash generation/disposal. Consequently the research targeting effective utilization of fly ash has also gained momentum. Fly ash has proved to be an economical substitute for expensive adsorbents as well as a suitable raw material for brick manufacturing, zeolite synthesis, etc. Fly ash is a reservoir of essential minerals but is deficient in nitrogen and phosphorus. By amending fly ash with soil and/or various organic materials (sewage sludge, bioprocess materials) as well as microbial inoculants likemore »« less
https://doi.org/10.1080/10643380701413690
Development of a novel geminal-difluorination method and its application in the synthesis of sup 18 F-labeled fatty acid analogues as potential myocardial imaging agents

Miscellaneous Pochapsky, S S

An efficient two-step fluorination procedure for transforming a ketone or aldehyde to the corresponding gem-difluoro compound has been developed. The gem-difluoro compounds can be prepared by first forming the corresponding 1,3-dithiolane followed by reaction with 1,3-dibromo-5,5-dimethylhydantoin and pyridinium poly(hydrogen fluoride). The reaction requires 2 equivalents of Br{sup +} and appears to proceed through a sequence of two bromosulfonium ions that open and cleave, respectively, to sulfur- and fluorine-stabilized carbocations that are trapped by fluoride ion. A convenient, general synthetic route to functionalized fatty acids has been developed and utilized in the synthesis of (16-{sup 18}F),6,6-trifluorohexadecanoic acid and (16-{sup 18}F)7,7-trifluorohexadecanoic acidmore »« less

Similar Records

Title: Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco‐friendly insecticides

Citation Formats

Physiological effects of biostable kinin and CAPA analogs in the Chagas disease vector, Rhodnius prolixus journal, November 2019

Peptidomimetic design journal, January 1998

Effect of helicokinins and ACE inhibitors on water balance and development of Heliothis virescens larvae journal, November 2000

Consensus chemistry and R-turn conformation of the active core of the insect kinin neuropeptide family journal, January 1997

The Kinin Peptide Family in Invertebrates journal, December 1999

Design, synthesis and aphicidal activity of N-terminal modified insect kinin analogs journal, June 2015

β-amino acid analogs of an insect neuropeptide feature potent bioactivity and resistance to peptidase hydrolysis journal, January 2007

The endopeptidase activity and the activation by Cl− of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica journal, March 1996

Synthesis, Biological Activity, and Conformational Study of N-Methylated Allatostatin Analogues Inhibiting Juvenile Hormone Biosynthesis journal, March 2015

The mosquito Aedes aegypti (L.) leucokinin receptor is a multiligand receptor for the three Aedes kinins journal, January 2005

Diuretic activity of C-terminal group analogues of the insect kinins in Acheta domesticus journal, January 1995

Prediction of Tight Turns and Their Types in Proteins journal, November 2000

Isolation, characterization and biological activity of a diuretic myokinin neuropeptide from the housefly, Musca domestica journal, January 1999

Inhibition of digestive enzyme release by neuropeptides in larvae of Opisina arenosella (Lepidoptera: Cryptophasidae) journal, June 2002

Identification of selective and non-selective, biostable β-amino acid agonists of recombinant insect kinin receptors from the southern cattle tick Boophilus microplus and mosquito Aedes aegypti journal, February 2008

Potential of natural peptidic compounds as leads for novel pesticides journal, January 1993

Aib-Containing Analogues of the Insect Kinin Neuropeptide Family Demonstrate Resistance to an Insect Angiotensin-Converting Enzyme and Potent Diuretic Activity journal, January 1997

New reagents, reactions, and peptidomimetics for drug design journal, January 2001

A Method of Computing the Effectiveness of an Insecticide journal, April 1925

Enhanced in vivo activity of peptidase-resistant analogs of the insect kinin neuropeptide family journal, April 2002

cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation journal, April 2002

Cloning and Expression of an Evolutionary Conserved Single-domain Angiotensin Converting Enzyme from Drosophila melanogaster journal, June 1995

The diuretic activity of a series of cephalomyotropic neuropeptides, the achetakinins, on isolated Malpighian tubules of the house cricket, Acheta domesticus journal, January 1990

Insect Neuropeptides journal, January 1990

Functional analysis of a G protein-coupled receptor from the Southern cattle tick Boophilus microplus (Acari: Ixodidae) identifies it as the first arthropod myokinin receptor journal, February 2003

Toward the Development of Novel Pest Management Agents Based upon Insect Kinin Neuropeptide Analogues journal, April 2009

Biostable agonists that match or exceed activity of native insect kinins on recombinant arthropod GPCRs journal, May 2009

β-Peptides: From Structure to Function journal, October 2001

Insect peptide hormones: a selective review of their physiology and potential application for pest control: Insect peptide hormones journal, July 2003

Antifeedant activity and high mortality in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae) induced by biostable insect kinin analogs journal, March 2010

A worldwide survey of neonicotinoids in honey journal, October 2017

Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid ( Myzus persicae and Macrosiphum rosae ) stress tolerance journal, February 2019

Biostable insect kinin analogs reduce blood meal and disrupt ecdysis in the blood-gorging Chagas’ disease vector, Rhodnius prolixus journal, June 2016

Eco-Friendly Insecticide Discovery via Peptidomimetics: Design, Synthesis, and Aphicidal Activity of Novel Insect Kinin Analogues journal, May 2015

Evaluation of Aib and PEG-polymer insect kinin analogs on mosquito and tick GPCRs identifies potent new pest management tools with potentially enhanced biostability and bioavailability journal, July 2019

Primary structure and synthesis of a blocked myotropic neuropeptide isolated from the cockroach, Leucophaea maderae journal, January 1986

Hydrolysis of Insect Neuropeptides by an Angiotensin-Converting Enzyme From the Housefly, Musca domestica journal, January 1997

A C-terminal aldehyde insect kinin analog enhances inhibition of weight gain and induces significant mortality in Helicoverpa zea larvae journal, October 2003

Comparative structure-activity analysis of insect kinin core analogs on recombinant kinin receptors from Southern cattle tickBoophilus microplus (Acari: Ixodidae) and mosquitoAedes aegypti (Diptera: Culicidae) journal, January 2006

Peptidomimetics, a synthetic tool of drug discovery journal, June 2008

Peptidomimetic therapeutics: scientific approaches and opportunities journal, February 2017

Advances in the application of neuropeptides in insect control journal, September 2000

Physiological effects of biostable kinin and CAPA analogs in the Chagas disease vector, Rhodnius prolixus
journal, November 2019

Peptidomimetic design
journal, January 1998

Effect of helicokinins and ACE inhibitors on water balance and development of Heliothis virescens larvae
journal, November 2000

Consensus chemistry and R-turn conformation of the active core of the insect kinin neuropeptide family
journal, January 1997

The Kinin Peptide Family in Invertebrates
journal, December 1999

Design, synthesis and aphicidal activity of N-terminal modified insect kinin analogs
journal, June 2015

β-amino acid analogs of an insect neuropeptide feature potent bioactivity and resistance to peptidase hydrolysis
journal, January 2007

The endopeptidase activity and the activation by Cl− of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica
journal, March 1996

Synthesis, Biological Activity, and Conformational Study of N-Methylated Allatostatin Analogues Inhibiting Juvenile Hormone Biosynthesis
journal, March 2015

The mosquito Aedes aegypti (L.) leucokinin receptor is a multiligand receptor for the three Aedes kinins
journal, January 2005

Diuretic activity of C-terminal group analogues of the insect kinins in Acheta domesticus
journal, January 1995

Prediction of Tight Turns and Their Types in Proteins
journal, November 2000

Isolation, characterization and biological activity of a diuretic myokinin neuropeptide from the housefly, Musca domestica
journal, January 1999

Inhibition of digestive enzyme release by neuropeptides in larvae of Opisina arenosella (Lepidoptera: Cryptophasidae)
journal, June 2002

Identification of selective and non-selective, biostable β-amino acid agonists of recombinant insect kinin receptors from the southern cattle tick Boophilus microplus and mosquito Aedes aegypti
journal, February 2008

Potential of natural peptidic compounds as leads for novel pesticides
journal, January 1993

Aib-Containing Analogues of the Insect Kinin Neuropeptide Family Demonstrate Resistance to an Insect Angiotensin-Converting Enzyme and Potent Diuretic Activity
journal, January 1997

New reagents, reactions, and peptidomimetics for drug design
journal, January 2001

A Method of Computing the Effectiveness of an Insecticide
journal, April 1925

Enhanced in vivo activity of peptidase-resistant analogs of the insect kinin neuropeptide family
journal, April 2002

cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation
journal, April 2002

Cloning and Expression of an Evolutionary Conserved Single-domain Angiotensin Converting Enzyme from Drosophila melanogaster
journal, June 1995

The diuretic activity of a series of cephalomyotropic neuropeptides, the achetakinins, on isolated Malpighian tubules of the house cricket, Acheta domesticus
journal, January 1990

Insect Neuropeptides
journal, January 1990

Functional analysis of a G protein-coupled receptor from the Southern cattle tick Boophilus microplus (Acari: Ixodidae) identifies it as the first arthropod myokinin receptor
journal, February 2003

Toward the Development of Novel Pest Management Agents Based upon Insect Kinin Neuropeptide Analogues
journal, April 2009

Biostable agonists that match or exceed activity of native insect kinins on recombinant arthropod GPCRs
journal, May 2009

β-Peptides: From Structure to Function
journal, October 2001

Insect peptide hormones: a selective review of their physiology and potential application for pest control: Insect peptide hormones
journal, July 2003

Antifeedant activity and high mortality in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae) induced by biostable insect kinin analogs
journal, March 2010

A worldwide survey of neonicotinoids in honey
journal, October 2017

Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid ( Myzus persicae and Macrosiphum rosae ) stress tolerance
journal, February 2019

Biostable insect kinin analogs reduce blood meal and disrupt ecdysis in the blood-gorging Chagas’ disease vector, Rhodnius prolixus
journal, June 2016

Eco-Friendly Insecticide Discovery via Peptidomimetics: Design, Synthesis, and Aphicidal Activity of Novel Insect Kinin Analogues
journal, May 2015

Evaluation of Aib and PEG-polymer insect kinin analogs on mosquito and tick GPCRs identifies potent new pest management tools with potentially enhanced biostability and bioavailability
journal, July 2019

Primary structure and synthesis of a blocked myotropic neuropeptide isolated from the cockroach, Leucophaea maderae
journal, January 1986

Hydrolysis of Insect Neuropeptides by an Angiotensin-Converting Enzyme From the Housefly, Musca domestica
journal, January 1997

A C-terminal aldehyde insect kinin analog enhances inhibition of weight gain and induces significant mortality in Helicoverpa zea larvae
journal, October 2003

Comparative structure-activity analysis of insect kinin core analogs on recombinant kinin receptors from Southern cattle tickBoophilus microplus (Acari: Ixodidae) and mosquitoAedes aegypti (Diptera: Culicidae)
journal, January 2006

Peptidomimetics, a synthetic tool of drug discovery
journal, June 2008

Peptidomimetic therapeutics: scientific approaches and opportunities
journal, February 2017

Advances in the application of neuropeptides in insect control
journal, September 2000