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Title: Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis

Authors:
; ; ; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1579432
Resource Type:
Published Article
Journal Name:
Journal of Food and Drug Analysis
Additional Journal Information:
Journal Name: Journal of Food and Drug Analysis Journal Volume: 28 Journal Issue: 1; Journal ID: ISSN 1021-9498
Publisher:
The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)
Country of Publication:
Country unknown/Code not available
Language:
English

Citation Formats

Xia, Qingsu, He, Xiaobo, Shi, Qiang, Lin, Ge, and Fu, Peter P. Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis. Country unknown/Code not available: N. p., 2020. Web. doi:10.1016/j.jfda.2019.12.001.
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Xia, Qingsu, He, Xiaobo, Shi, Qiang, Lin, Ge, & Fu, Peter P. Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis. Country unknown/Code not available. https://doi.org/10.1016/j.jfda.2019.12.001
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Xia, Qingsu, He, Xiaobo, Shi, Qiang, Lin, Ge, and Fu, Peter P. Wed . "Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis". Country unknown/Code not available. https://doi.org/10.1016/j.jfda.2019.12.001.
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@article{osti_1579432,
title = {Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis},
author = {Xia, Qingsu and He, Xiaobo and Shi, Qiang and Lin, Ge and Fu, Peter P.},
abstractNote = {},
doi = {10.1016/j.jfda.2019.12.001},
journal = {Journal of Food and Drug Analysis},
number = 1,
volume = 28,
place = {Country unknown/Code not available},
year = {2020},
month = {1}
}
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Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1016/j.jfda.2019.12.001
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Works referenced in this record:

Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease
journal, December 2014

  • Edgar, John A.; Molyneux, Russell J.; Colegate, Steven M.
  • Chemical Research in Toxicology, Vol. 28, Issue 1
  • DOI: 10.1021/tx500403t

Metabolic Activation of the Tumorigenic Pyrrolizidine Alkaloid, Riddelliine, Leading to DNA Adduct Formation in Vivo
journal, January 2001

  • Yang, Ya-Chen; Yan, Jian; Doerge, Daniel R.
  • Chemical Research in Toxicology, Vol. 14, Issue 1
  • DOI: 10.1021/tx000150n

7-Glutathione Pyrrole Adduct: A Potential DNA Reactive Metabolite of Pyrrolizidine Alkaloids
journal, March 2015

  • Xia, Qingsu; Ma, Liang; He, Xiaobo
  • Chemical Research in Toxicology, Vol. 28, Issue 4
  • DOI: 10.1021/tx500417q

7- N -Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids
journal, October 2016

1-Formyl-7-hydroxy-6,7-dihydro-5 H -pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids
journal, May 2019

Preparation of rat liver cells
journal, October 1972

Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity
journal, August 2013

  • Xia, Qingsu; Zhao, Yuewei; Von Tungeln, Linda S.
  • Chemical Research in Toxicology, Vol. 26, Issue 9
  • DOI: 10.1021/tx400241c

Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms
journal, January 2004

  • Fu, Peter P.; Xia, Qingsu; Lin, Ge
  • Drug Metabolism Reviews, Vol. 36, Issue 1
  • DOI: 10.1081/DMR-120028426

Species differences in the hepatic microsomal enzyme metabolism of the pyrrolizidine alkaloids
journal, October 1998

Detection of Pyrrolizidine Alkaloid DNA Adducts in Livers of Cattle Poisoned with Heliotropium europaeum
journal, February 2017

Pyrrolizidine Alkaloid-Protein Adducts: Potential Non-invasive Biomarkers of Pyrrolizidine Alkaloid-Induced Liver Toxicity and Exposure
journal, July 2016

Pyrrolizidine Alkaloids: Metabolic Activation Pathways Leading to Liver Tumor Initiation
journal, November 2016

Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis
journal, May 2014

  • Ruan, Jianqing; Yang, Mengbi; Fu, Peter
  • Chemical Research in Toxicology, Vol. 27, Issue 6
  • DOI: 10.1021/tx500071q

Involvement of cytochrome P450 3A in the metabolism and covalent binding of14C-monocrotaline in rat liver microsomes
journal, January 1998

7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids
journal, March 2017

7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids
journal, September 2015

Toxicity and Metabolism of Pyrrolizidine Alkaloids
journal, January 1988

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