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Title: Raman mapping of fentanyl transdermal delivery systems with off-label modifications

Abstract

Raman mapping and chemometric models were used to characterize crystal formation in fentanyl transdermal delivery systems resulting from off-label modifications.

Authors:
 [1]; ORCiD logo [1]; ORCiD logo [1];  [2]; ORCiD logo [1]; ORCiD logo [1];  [1]
  1. Food and Drug Administration (FDA)/Center for Drug Evaluation and Research (CDER)/Office of Pharmaceutical Quality (OPQ)/Office of Testing and Research (OTR)/Division of Pharmaceutical Analysis (DPA), St Louis, USA
  2. FDA/CDER/OPQ/Office of New Drug Products (ONDP), Silver Spring, USA
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1579278
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Analyst
Additional Journal Information:
Journal Name: Analyst; Journal ID: ISSN 0003-2654
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Xu, Teng, Yilmaz, Huzeyfe, Willett, Daniel R., Strasinger, Caroline, Rodriguez, Jason D., Keire, David A., and Wokovich, Anna M. Raman mapping of fentanyl transdermal delivery systems with off-label modifications. United Kingdom: N. p., 2020. Web. doi:10.1039/C9AN01289C.
Xu, Teng, Yilmaz, Huzeyfe, Willett, Daniel R., Strasinger, Caroline, Rodriguez, Jason D., Keire, David A., & Wokovich, Anna M. Raman mapping of fentanyl transdermal delivery systems with off-label modifications. United Kingdom. doi:10.1039/C9AN01289C.
Xu, Teng, Yilmaz, Huzeyfe, Willett, Daniel R., Strasinger, Caroline, Rodriguez, Jason D., Keire, David A., and Wokovich, Anna M. Wed . "Raman mapping of fentanyl transdermal delivery systems with off-label modifications". United Kingdom. doi:10.1039/C9AN01289C.
@article{osti_1579278,
title = {Raman mapping of fentanyl transdermal delivery systems with off-label modifications},
author = {Xu, Teng and Yilmaz, Huzeyfe and Willett, Daniel R. and Strasinger, Caroline and Rodriguez, Jason D. and Keire, David A. and Wokovich, Anna M.},
abstractNote = {Raman mapping and chemometric models were used to characterize crystal formation in fentanyl transdermal delivery systems resulting from off-label modifications.},
doi = {10.1039/C9AN01289C},
journal = {Analyst},
number = ,
volume = ,
place = {United Kingdom},
year = {2020},
month = {1}
}

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