LGI1 antibody‐associated limbic encephalitis started from unilateral basal ganglia to medial temporal lobe and insula
Abstract
Abstract Leucine‐rich glioma‐inactivated 1 (LGI1) antibody‐associated limbic encephalitis is a rare autoimmune encephalitis. Here, we report a 39‐year‐old woman presented with generalized tonic‐clonic seizures, night delirium, bilateral upper limb tremor, and hyponatremia. Her symptoms did not improve with initial steroid therapy, and brain magnetic resonance imaging (MRI) showed a progression of abnormalities from right basal ganglia to medial temporal lobe and insula. The presence of LGI1 antibodies in the patient's serum confirmed the clinical diagnosis. After the combined treatments of methylprednisolone, plasma exchange, and intravenous immunoglobulin, her clinical symptoms resolved completely.
- Authors:
-
[1];
[1];
[1];
- Department of Neurology Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Kitaku Okayama Japan
- Publication Date:
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1577905
- Resource Type:
- Publisher's Accepted Manuscript
- Journal Name:
- Neurology and Clinical Neuroscience
- Additional Journal Information:
- Journal Name: Neurology and Clinical Neuroscience Journal Volume: 8 Journal Issue: 2; Journal ID: ISSN 2049-4173
- Publisher:
- Wiley-Blackwell
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Citation Formats
Liu, Xia, Omote, Yoshio, Osakada, Yosuke, Tadokoro, Koh, Takemoto, Mami, Hishikawa, Nozomi, Yamashita, Toru, Ohta, Yasuyuki, and Abe, Koji. LGI1 antibody‐associated limbic encephalitis started from unilateral basal ganglia to medial temporal lobe and insula. Country unknown/Code not available: N. p., 2019.
Web. doi:10.1111/ncn3.12351.
Liu, Xia, Omote, Yoshio, Osakada, Yosuke, Tadokoro, Koh, Takemoto, Mami, Hishikawa, Nozomi, Yamashita, Toru, Ohta, Yasuyuki, & Abe, Koji. LGI1 antibody‐associated limbic encephalitis started from unilateral basal ganglia to medial temporal lobe and insula. Country unknown/Code not available. https://doi.org/10.1111/ncn3.12351
Liu, Xia, Omote, Yoshio, Osakada, Yosuke, Tadokoro, Koh, Takemoto, Mami, Hishikawa, Nozomi, Yamashita, Toru, Ohta, Yasuyuki, and Abe, Koji. Mon .
"LGI1 antibody‐associated limbic encephalitis started from unilateral basal ganglia to medial temporal lobe and insula". Country unknown/Code not available. https://doi.org/10.1111/ncn3.12351.
@article{osti_1577905,
title = {LGI1 antibody‐associated limbic encephalitis started from unilateral basal ganglia to medial temporal lobe and insula},
author = {Liu, Xia and Omote, Yoshio and Osakada, Yosuke and Tadokoro, Koh and Takemoto, Mami and Hishikawa, Nozomi and Yamashita, Toru and Ohta, Yasuyuki and Abe, Koji},
abstractNote = {Abstract Leucine‐rich glioma‐inactivated 1 (LGI1) antibody‐associated limbic encephalitis is a rare autoimmune encephalitis. Here, we report a 39‐year‐old woman presented with generalized tonic‐clonic seizures, night delirium, bilateral upper limb tremor, and hyponatremia. Her symptoms did not improve with initial steroid therapy, and brain magnetic resonance imaging (MRI) showed a progression of abnormalities from right basal ganglia to medial temporal lobe and insula. The presence of LGI1 antibodies in the patient's serum confirmed the clinical diagnosis. After the combined treatments of methylprednisolone, plasma exchange, and intravenous immunoglobulin, her clinical symptoms resolved completely.},
doi = {10.1111/ncn3.12351},
journal = {Neurology and Clinical Neuroscience},
number = 2,
volume = 8,
place = {Country unknown/Code not available},
year = {Mon Dec 09 00:00:00 EST 2019},
month = {Mon Dec 09 00:00:00 EST 2019}
}
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