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Title: The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

Abstract

Transformative technologies are enabling the construction of three dimensional (3D) maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) aims to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, and the biomedical research community at large towards the shared vision of a comprehensive, accessible 3D molecular and cellular atlas of the human body, in health and various disease settings.

Authors:
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  1. Stanford University
  2. University of Washington
  3. University of Florida
  4. Broad Institute
  5. Broad Institute of MIT and Harvard
  6. New York Genome Center
  7. Harvard Medical School
  8. Purdue University
  9. University of Pittsburgh
  10. Carnegie Mellon University
  11. University of California, San Diego
  12. Indiana University-Bloomington
  13. Washington University In Saint Louis
  14. National Institute of Health
  15. California Institute of Technology
  16. University of Rochester
  17. Institute of Molecular Life Sciences
  18. VISITORS
  19. Vanderbilt University
  20. Delft University of Technology
  21. Dana-Farber Cancer Institute
  22. Harvard University
  23. Marquette University,
  24. BATTELLE (PACIFIC NW LAB)
  25. Wellcome Sanger Institute
  26. Jack Baskin School of Engineering
  27. Opto-Knowledge Systems, Inc
  28. Pittsburgh Supercomputing Center
  29. University of South Dakota
  30. University of North Carolina at Chapel Hill
  31. Knowinnovation Inc
  32. University of Cambridge
  33. Massachusetts Institute of Technology
  34. National Heart, Lung, and Blood Institute
  35. National Institute of Diabetes and Digestive and Kidney Diseases
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
Contributing Org.:
HuBMAP Consortium
OSTI Identifier:
1577443
Report Number(s):
PNNL-SA-146510
Journal ID: ISSN 0028-0836
Grant/Contract Number:  
AC05-76RL01830
Resource Type:
Accepted Manuscript
Journal Name:
Nature (London)
Additional Journal Information:
Journal Name: Nature (London); Journal Volume: 574; Journal Issue: 7777; Journal ID: ISSN 0028-0836
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Snyder, Michael, Lin, Shin, Posgai, Amanda, Atkinson, Mark A., Regev, Aviv, Rood, Jennifer, Rozenblatt-Rosen, Orit, Gaffney, Leslie, Hupalowska, Anna, Satija, Rahul, Gehlenborg, Nils, Shendure, Jay, Laskin, Julia, Harbury, Pehr, Nystrom, Nicholas, Silverstein, Jonathan C., Bar-Joseph, Ziv, Zhang, Kun, Borner, Katy, Lin, Yiin, Conroy, Richard, Procaccini, Dena, Roy, Ananda, Pillai, Ajay, Brown, Marishka, Galis, Zorina S., Long, Cai, Trapnell, Cole, Jackson, Dana, Nolan, Garry, Greenleaf, William J., Plevritis, Sylvia K., Ahadi, Sara, Nevins, Stephanie A., Lee, Hayan, Schuerch, Christian M., Black, Sarah, Venkataraaman, Vishal G., Esplin, Edward D., Horning, Aaron, Bahmani, Amir, Sun, Xin, Jain, Sanjay, Hagood, James, Pryhuber, Gloria, Kharchenko, Peter, Bodenmiller, Bernd, Brusko, Todd, Clare-Salzler, Micheal, Nick, Harry, Otto, Kevin, Wasserfall, Clive, Jorgensen, Marda, Brusko, Maigan, Maffioletti, Sergio, Caprioli, Richard M., Spraggins, Jeffrey, Gutierrez, Dainelle, Patterson, Nathan H., Neumann, Elizabeth K., Harris, Raymond, deCaestecker, Mark, Fogo, Agnes B., Van de Plas, Raf, Lau, Ken, Yuan, Guo-Cheng, Zhu, Qian, Dries, Ruben, Yin, Peng, Saka, Sinem K., Kishi, Jocelyn Y., Wang, Yu, Goldaracena, Isabel, Ye, DongeHye, Burnum-Johnson, Kristin E., Piehowski, Paul D., Ansong, Charles K., Zhu, Ying, Tushar, Desai, Mulye, Jay, Chou, Peter, Nagendran, Monica, Teichmann, Sarah A., Paten, Benedict, Murphy, Robert F., Ma, Jian, Kiselev, Vladimir, Kingsford, Carl, Ricarte, Allyson, Keays, Maria, Akoju, Sushma A., Ruffalo, Matthew, Vella, Margaret, McCallum, Chuck, Cross, Leonard, Friedman, Samuel H., Heiland, Randy, Herr, Bruce, Macklin, Paul, Quardokus, Ellen M., Record, Lisel, Sluka, James P., Weber, Griffin M., Blood, Philip D., Ropelewski, Alexander J., Shirley, William E., Scibek, Robin M., Mabee, Paula, Lenhardt, Christopher C., Robasky, Kimberly, Michailidis, Stravos, Marioni, John, Butler, Andrew, Stuart, Tim, Fisher, Eyal, Ghazanfar, Shila, Eraslan, Gocken, Biancalani, Tommaso, Vaishnav, Eeshit D., Srinivas, Pothur R., Pawlyk, Aaron, Sechi, Salvatore, Wilder, Elizabeth, and Anderson, James. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program. United States: N. p., 2019. Web. doi:10.1038/s41586-019-1629-x.
Snyder, Michael, Lin, Shin, Posgai, Amanda, Atkinson, Mark A., Regev, Aviv, Rood, Jennifer, Rozenblatt-Rosen, Orit, Gaffney, Leslie, Hupalowska, Anna, Satija, Rahul, Gehlenborg, Nils, Shendure, Jay, Laskin, Julia, Harbury, Pehr, Nystrom, Nicholas, Silverstein, Jonathan C., Bar-Joseph, Ziv, Zhang, Kun, Borner, Katy, Lin, Yiin, Conroy, Richard, Procaccini, Dena, Roy, Ananda, Pillai, Ajay, Brown, Marishka, Galis, Zorina S., Long, Cai, Trapnell, Cole, Jackson, Dana, Nolan, Garry, Greenleaf, William J., Plevritis, Sylvia K., Ahadi, Sara, Nevins, Stephanie A., Lee, Hayan, Schuerch, Christian M., Black, Sarah, Venkataraaman, Vishal G., Esplin, Edward D., Horning, Aaron, Bahmani, Amir, Sun, Xin, Jain, Sanjay, Hagood, James, Pryhuber, Gloria, Kharchenko, Peter, Bodenmiller, Bernd, Brusko, Todd, Clare-Salzler, Micheal, Nick, Harry, Otto, Kevin, Wasserfall, Clive, Jorgensen, Marda, Brusko, Maigan, Maffioletti, Sergio, Caprioli, Richard M., Spraggins, Jeffrey, Gutierrez, Dainelle, Patterson, Nathan H., Neumann, Elizabeth K., Harris, Raymond, deCaestecker, Mark, Fogo, Agnes B., Van de Plas, Raf, Lau, Ken, Yuan, Guo-Cheng, Zhu, Qian, Dries, Ruben, Yin, Peng, Saka, Sinem K., Kishi, Jocelyn Y., Wang, Yu, Goldaracena, Isabel, Ye, DongeHye, Burnum-Johnson, Kristin E., Piehowski, Paul D., Ansong, Charles K., Zhu, Ying, Tushar, Desai, Mulye, Jay, Chou, Peter, Nagendran, Monica, Teichmann, Sarah A., Paten, Benedict, Murphy, Robert F., Ma, Jian, Kiselev, Vladimir, Kingsford, Carl, Ricarte, Allyson, Keays, Maria, Akoju, Sushma A., Ruffalo, Matthew, Vella, Margaret, McCallum, Chuck, Cross, Leonard, Friedman, Samuel H., Heiland, Randy, Herr, Bruce, Macklin, Paul, Quardokus, Ellen M., Record, Lisel, Sluka, James P., Weber, Griffin M., Blood, Philip D., Ropelewski, Alexander J., Shirley, William E., Scibek, Robin M., Mabee, Paula, Lenhardt, Christopher C., Robasky, Kimberly, Michailidis, Stravos, Marioni, John, Butler, Andrew, Stuart, Tim, Fisher, Eyal, Ghazanfar, Shila, Eraslan, Gocken, Biancalani, Tommaso, Vaishnav, Eeshit D., Srinivas, Pothur R., Pawlyk, Aaron, Sechi, Salvatore, Wilder, Elizabeth, & Anderson, James. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program. United States. doi:10.1038/s41586-019-1629-x.
Snyder, Michael, Lin, Shin, Posgai, Amanda, Atkinson, Mark A., Regev, Aviv, Rood, Jennifer, Rozenblatt-Rosen, Orit, Gaffney, Leslie, Hupalowska, Anna, Satija, Rahul, Gehlenborg, Nils, Shendure, Jay, Laskin, Julia, Harbury, Pehr, Nystrom, Nicholas, Silverstein, Jonathan C., Bar-Joseph, Ziv, Zhang, Kun, Borner, Katy, Lin, Yiin, Conroy, Richard, Procaccini, Dena, Roy, Ananda, Pillai, Ajay, Brown, Marishka, Galis, Zorina S., Long, Cai, Trapnell, Cole, Jackson, Dana, Nolan, Garry, Greenleaf, William J., Plevritis, Sylvia K., Ahadi, Sara, Nevins, Stephanie A., Lee, Hayan, Schuerch, Christian M., Black, Sarah, Venkataraaman, Vishal G., Esplin, Edward D., Horning, Aaron, Bahmani, Amir, Sun, Xin, Jain, Sanjay, Hagood, James, Pryhuber, Gloria, Kharchenko, Peter, Bodenmiller, Bernd, Brusko, Todd, Clare-Salzler, Micheal, Nick, Harry, Otto, Kevin, Wasserfall, Clive, Jorgensen, Marda, Brusko, Maigan, Maffioletti, Sergio, Caprioli, Richard M., Spraggins, Jeffrey, Gutierrez, Dainelle, Patterson, Nathan H., Neumann, Elizabeth K., Harris, Raymond, deCaestecker, Mark, Fogo, Agnes B., Van de Plas, Raf, Lau, Ken, Yuan, Guo-Cheng, Zhu, Qian, Dries, Ruben, Yin, Peng, Saka, Sinem K., Kishi, Jocelyn Y., Wang, Yu, Goldaracena, Isabel, Ye, DongeHye, Burnum-Johnson, Kristin E., Piehowski, Paul D., Ansong, Charles K., Zhu, Ying, Tushar, Desai, Mulye, Jay, Chou, Peter, Nagendran, Monica, Teichmann, Sarah A., Paten, Benedict, Murphy, Robert F., Ma, Jian, Kiselev, Vladimir, Kingsford, Carl, Ricarte, Allyson, Keays, Maria, Akoju, Sushma A., Ruffalo, Matthew, Vella, Margaret, McCallum, Chuck, Cross, Leonard, Friedman, Samuel H., Heiland, Randy, Herr, Bruce, Macklin, Paul, Quardokus, Ellen M., Record, Lisel, Sluka, James P., Weber, Griffin M., Blood, Philip D., Ropelewski, Alexander J., Shirley, William E., Scibek, Robin M., Mabee, Paula, Lenhardt, Christopher C., Robasky, Kimberly, Michailidis, Stravos, Marioni, John, Butler, Andrew, Stuart, Tim, Fisher, Eyal, Ghazanfar, Shila, Eraslan, Gocken, Biancalani, Tommaso, Vaishnav, Eeshit D., Srinivas, Pothur R., Pawlyk, Aaron, Sechi, Salvatore, Wilder, Elizabeth, and Anderson, James. Wed . "The human body at cellular resolution: the NIH Human Biomolecular Atlas Program". United States. doi:10.1038/s41586-019-1629-x. https://www.osti.gov/servlets/purl/1577443.
@article{osti_1577443,
title = {The human body at cellular resolution: the NIH Human Biomolecular Atlas Program},
author = {Snyder, Michael and Lin, Shin and Posgai, Amanda and Atkinson, Mark A. and Regev, Aviv and Rood, Jennifer and Rozenblatt-Rosen, Orit and Gaffney, Leslie and Hupalowska, Anna and Satija, Rahul and Gehlenborg, Nils and Shendure, Jay and Laskin, Julia and Harbury, Pehr and Nystrom, Nicholas and Silverstein, Jonathan C. and Bar-Joseph, Ziv and Zhang, Kun and Borner, Katy and Lin, Yiin and Conroy, Richard and Procaccini, Dena and Roy, Ananda and Pillai, Ajay and Brown, Marishka and Galis, Zorina S. and Long, Cai and Trapnell, Cole and Jackson, Dana and Nolan, Garry and Greenleaf, William J. and Plevritis, Sylvia K. and Ahadi, Sara and Nevins, Stephanie A. and Lee, Hayan and Schuerch, Christian M. and Black, Sarah and Venkataraaman, Vishal G. and Esplin, Edward D. and Horning, Aaron and Bahmani, Amir and Sun, Xin and Jain, Sanjay and Hagood, James and Pryhuber, Gloria and Kharchenko, Peter and Bodenmiller, Bernd and Brusko, Todd and Clare-Salzler, Micheal and Nick, Harry and Otto, Kevin and Wasserfall, Clive and Jorgensen, Marda and Brusko, Maigan and Maffioletti, Sergio and Caprioli, Richard M. and Spraggins, Jeffrey and Gutierrez, Dainelle and Patterson, Nathan H. and Neumann, Elizabeth K. and Harris, Raymond and deCaestecker, Mark and Fogo, Agnes B. and Van de Plas, Raf and Lau, Ken and Yuan, Guo-Cheng and Zhu, Qian and Dries, Ruben and Yin, Peng and Saka, Sinem K. and Kishi, Jocelyn Y. and Wang, Yu and Goldaracena, Isabel and Ye, DongeHye and Burnum-Johnson, Kristin E. and Piehowski, Paul D. and Ansong, Charles K. and Zhu, Ying and Tushar, Desai and Mulye, Jay and Chou, Peter and Nagendran, Monica and Teichmann, Sarah A. and Paten, Benedict and Murphy, Robert F. and Ma, Jian and Kiselev, Vladimir and Kingsford, Carl and Ricarte, Allyson and Keays, Maria and Akoju, Sushma A. and Ruffalo, Matthew and Vella, Margaret and McCallum, Chuck and Cross, Leonard and Friedman, Samuel H. and Heiland, Randy and Herr, Bruce and Macklin, Paul and Quardokus, Ellen M. and Record, Lisel and Sluka, James P. and Weber, Griffin M. and Blood, Philip D. and Ropelewski, Alexander J. and Shirley, William E. and Scibek, Robin M. and Mabee, Paula and Lenhardt, Christopher C. and Robasky, Kimberly and Michailidis, Stravos and Marioni, John and Butler, Andrew and Stuart, Tim and Fisher, Eyal and Ghazanfar, Shila and Eraslan, Gocken and Biancalani, Tommaso and Vaishnav, Eeshit D. and Srinivas, Pothur R. and Pawlyk, Aaron and Sechi, Salvatore and Wilder, Elizabeth and Anderson, James},
abstractNote = {Transformative technologies are enabling the construction of three dimensional (3D) maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) aims to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, and the biomedical research community at large towards the shared vision of a comprehensive, accessible 3D molecular and cellular atlas of the human body, in health and various disease settings.},
doi = {10.1038/s41586-019-1629-x},
journal = {Nature (London)},
number = 7777,
volume = 574,
place = {United States},
year = {2019},
month = {10}
}

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Works referenced in this record:

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
journal, March 2019


Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry
journal, May 2018


An Immune Atlas of Clear Cell Renal Cell Carcinoma
journal, May 2017

  • Chevrier, Stéphane; Levine, Jacob Harrison; Zanotelli, Vito Riccardo Tomaso
  • Cell, Vol. 169, Issue 4
  • DOI: 10.1016/j.cell.2017.04.016

Scaling single-cell genomics from phenomenology to mechanism
journal, January 2017


The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas
journal, November 2017


The Cardiac Atlas Project—an imaging database for computational modeling and statistical atlases of the heart
journal, July 2011


Factors That Influence the Quality of RNA From the Pancreas of Organ Donors
journal, January 2017


Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data
journal, October 2018

  • Zhu, Qian; Shah, Sheel; Dries, Ruben
  • Nature Biotechnology, Vol. 36, Issue 12
  • DOI: 10.1038/nbt.4260

The Human Cell Atlas
journal, December 2017


Power analysis of single-cell RNA-sequencing experiments
journal, March 2017

  • Svensson, Valentine; Natarajan, Kedar Nath; Ly, Lam-Ha
  • Nature Methods, Vol. 14, Issue 4
  • DOI: 10.1038/nmeth.4220

Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping
journal, February 2015

  • Van de Plas, Raf; Yang, Junhai; Spraggins, Jeffrey
  • Nature Methods, Vol. 12, Issue 4
  • DOI: 10.1038/nmeth.3296

CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
journal, February 2018


In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus
journal, October 2016


Toil enables reproducible, open source, big biomedical data analyses
journal, April 2017

  • Vivian, John; Rao, Arjun Arkal; Nothaft, Frank Austin
  • Nature Biotechnology, Vol. 35, Issue 4
  • DOI: 10.1038/nbt.3772

Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry
journal, January 2018

  • Schulz, Daniel; Zanotelli, Vito Riccardo Tomaso; Fischer, Jana Raja
  • Cell Systems, Vol. 6, Issue 1
  • DOI: 10.1016/j.cels.2017.12.001

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging
journal, August 2018


Comprehensive single-cell transcriptional profiling of a multicellular organism
journal, August 2017


Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
journal, May 2015


Erratum to: A benchmark for RNA-seq quantification pipelines
journal, September 2016


Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes: Tissue Biobank for Diabetes
journal, October 2012

  • Campbell-Thompson, Martha; Wasserfall, Clive; Kaddis, John
  • Diabetes/Metabolism Research and Reviews, Vol. 28, Issue 7
  • DOI: 10.1002/dmrr.2316

Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues
journal, August 2019


Expression Atlas update—an integrated database of gene and protein expression in humans, animals and plants
journal, October 2015

  • Petryszak, Robert; Keays, Maria; Tang, Y. Amy
  • Nucleic Acids Research, Vol. 44, Issue D1
  • DOI: 10.1093/nar/gkv1045

Single-cell in situ RNA profiling by sequential hybridization
journal, March 2014

  • Lubeck, Eric; Coskun, Ahmet F.; Zhiyentayev, Timur
  • Nature Methods, Vol. 11, Issue 4
  • DOI: 10.1038/nmeth.2892

The FAIR Guiding Principles for scientific data management and stewardship
journal, March 2016

  • Wilkinson, Mark D.; Dumontier, Michel; Aalbersberg, IJsbrand Jan
  • Scientific Data, Vol. 3, Issue 1
  • DOI: 10.1038/sdata.2016.18

High Spatial Resolution Imaging of Mouse Pancreatic Islets Using Nanospray Desorption Electrospray Ionization Mass Spectrometry
journal, April 2018


Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors
journal, April 2018

  • Haghverdi, Laleh; Lun, Aaron T. L.; Morgan, Michael D.
  • Nature Biotechnology, Vol. 36, Issue 5
  • DOI: 10.1038/nbt.4091

SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues
journal, May 2019


Integrating single-cell transcriptomic data across different conditions, technologies, and species
journal, April 2018

  • Butler, Andrew; Hoffman, Paul; Smibert, Peter
  • Nature Biotechnology, Vol. 36, Issue 5
  • DOI: 10.1038/nbt.4096

A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility
journal, August 2018


Ultrasensitive optical imaging with lanthanide lumiphores
journal, November 2017

  • Cho, Ukrae; Riordan, Daniel P.; Ciepla, Paulina
  • Nature Chemical Biology, Vol. 14, Issue 1
  • DOI: 10.1038/nchembio.2513

Analysis of Tissue Specimens by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry in Biological and Clinical Research
journal, February 2013

  • Norris, Jeremy L.; Caprioli, Richard M.
  • Chemical Reviews, Vol. 113, Issue 4
  • DOI: 10.1021/cr3004295

The Dockstore: enabling modular, community-focused sharing of Docker-based genomics tools and workflows
journal, January 2017


histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data
journal, August 2017

  • Schapiro, Denis; Jackson, Hartland W.; Raghuraman, Swetha
  • Nature Methods, Vol. 14, Issue 9
  • DOI: 10.1038/nmeth.4391

Single-cell epigenomics: techniques and emerging applications
journal, October 2015

  • Schwartzman, Omer; Tanay, Amos
  • Nature Reviews Genetics, Vol. 16, Issue 12
  • DOI: 10.1038/nrg3980

Single-cell chromatin accessibility reveals principles of regulatory variation
journal, June 2015

  • Buenrostro, Jason D.; Wu, Beijing; Litzenburger, Ulrike M.
  • Nature, Vol. 523, Issue 7561
  • DOI: 10.1038/nature14590

An interactive framework for whole-brain maps at cellular resolution
journal, December 2017


Principles of metadata organization at the ENCODE data coordination center
journal, January 2016


Next Generation Histology-Directed Imaging Mass Spectrometry Driven by Autofluorescence Microscopy
journal, October 2018


A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM)
journal, August 2001

  • Mazziotta, John; Toga, Arthur; Evans, Alan
  • Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, Vol. 356, Issue 1412
  • DOI: 10.1098/rstb.2001.0915