Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions
Abstract
We present a multilayer dropmaker geometry that enables the modular fabrication of microfluidic devices containing precisely patterned channel surface wettability. The platform is used for the scalable production of uniform double emulsion drops.
- Authors:
-
- School of Engineering and Applied Sciences, Harvard University, Cambridge, USA
- Lawrence Livermore National Laboratory, Livermore, USA
- School of Engineering and Applied Sciences, Harvard University, Cambridge, USA, School of Chemical Engineering and Technology
- School of Engineering and Applied Sciences, Harvard University, Cambridge, USA, Department of Physics
- Publication Date:
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1576640
- Grant/Contract Number:
- AC52-07NA27344
- Resource Type:
- Publisher's Accepted Manuscript
- Journal Name:
- Lab on a chip (Print)
- Additional Journal Information:
- Journal Name: Lab on a chip (Print) Journal Volume: 20 Journal Issue: 1; Journal ID: ISSN 1473-0197
- Publisher:
- Royal Society of Chemistry (RSC)
- Country of Publication:
- France
- Language:
- English
Citation Formats
Nawar, Saraf, Stolaroff, Joshuah K., Ye, Congwang, Wu, Huayin, Nguyen, Du Thai, Xin, Feng, and Weitz, David A. Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions. France: N. p., 2020.
Web. doi:10.1039/C9LC00966C.
Nawar, Saraf, Stolaroff, Joshuah K., Ye, Congwang, Wu, Huayin, Nguyen, Du Thai, Xin, Feng, & Weitz, David A. Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions. France. doi:10.1039/C9LC00966C.
Nawar, Saraf, Stolaroff, Joshuah K., Ye, Congwang, Wu, Huayin, Nguyen, Du Thai, Xin, Feng, and Weitz, David A. Wed .
"Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions". France. doi:10.1039/C9LC00966C.
@article{osti_1576640,
title = {Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions},
author = {Nawar, Saraf and Stolaroff, Joshuah K. and Ye, Congwang and Wu, Huayin and Nguyen, Du Thai and Xin, Feng and Weitz, David A.},
abstractNote = {We present a multilayer dropmaker geometry that enables the modular fabrication of microfluidic devices containing precisely patterned channel surface wettability. The platform is used for the scalable production of uniform double emulsion drops.},
doi = {10.1039/C9LC00966C},
journal = {Lab on a chip (Print)},
number = 1,
volume = 20,
place = {France},
year = {2020},
month = {1}
}
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1039/C9LC00966C
DOI: 10.1039/C9LC00966C
Other availability
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Low temperature and deformation-free bonding of PMMA microfluidic devices with stable hydrophilicity via oxygen plasma treatment and PVA coating
journal, January 2015
- Yu, H.; Chong, Z. Z.; Tor, S. B.
- RSC Advances, Vol. 5, Issue 11
Encapsulation and Enhanced Retention of Fragrance in Polymer Microcapsules
journal, September 2015
- Lee, Hyomin; Choi, Chang-Hyung; Abbaspourrad, Alireza
- ACS Applied Materials & Interfaces, Vol. 8, Issue 6
Droplets Formation and Merging in Two-Phase Flow Microfluidics
journal, April 2011
- Gu, Hao; Duits, Michel H. G.; Mugele, Frieder
- International Journal of Molecular Sciences, Vol. 12, Issue 4
Mechanisms of Oxygen Plasma Nanotexturing of Organic Polymer Surfaces: From Stable Super Hydrophilic to Super Hydrophobic Surfaces
journal, October 2009
- Tsougeni, K.; Vourdas, N.; Tserepi, A.
- Langmuir, Vol. 25, Issue 19
Fabrication and characterization of poly(methylmethacrylate) microfluidic devices bonded using surface modifications and solvents
journal, January 2006
- Brown, Laurie; Koerner, Terry; Horton, J. Hugh
- Lab Chip, Vol. 6, Issue 1
Monodisperse Double Emulsions Generated from a Microcapillary Device
journal, April 2005
- Utada, A. S.
- Science, Vol. 308, Issue 5721
Double emulsions based on silicone-fluorocarbon-water and their skin penetration
journal, February 2016
- Mahrhauser, Denise-Silvia; Fischer, Claudia; Valenta, Claudia
- International Journal of Pharmaceutics, Vol. 498, Issue 1-2
Microencapsulation of pesticides and their improved handling safety
journal, January 2001
- Tsuji, K.
- Journal of Microencapsulation, Vol. 18, Issue 2
High-volume production of single and compound emulsions in a microfluidic parallelization arrangement coupled with coaxial annular world-to-chip interfaces
journal, January 2012
- Nisisako, Takasi; Ando, Takuya; Hatsuzawa, Takeshi
- Lab on a Chip, Vol. 12, Issue 18
Silicon and glass very large scale microfluidic droplet integration for terascale generation of polymer microparticles
journal, March 2018
- Yadavali, Sagar; Jeong, Heon-Ho; Lee, Daeyeon
- Nature Communications, Vol. 9, Issue 1
Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability
journal, January 2008
- Abate, Adam R.; Krummel, Amber T.; Lee, Daeyeon
- Lab on a Chip, Vol. 8, Issue 12
Functionalization of Polymer Sensor Surfaces by Oxygen Plasma Treatment
journal, September 2009
- Landgraf, R.; Kaiser, M. -K.; Posseckardt, J.
- Procedia Chemistry, Vol. 1, Issue 1
Microfluidic synthesis of advanced microparticles for encapsulation and controlled release
journal, January 2012
- Duncanson, Wynter J.; Lin, Tina; Abate, Adam R.
- Lab on a Chip, Vol. 12, Issue 12
Patterning microfluidic device wettability using flow confinement
journal, January 2010
- Abate, Adam R.; Thiele, Julian; Weinhart, Marie
- Lab on a Chip, Vol. 10, Issue 14
High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping
journal, March 2015
- Femmer, Tim; Jans, Alexander; Eswein, Rudi
- ACS Applied Materials & Interfaces, Vol. 7, Issue 23
Influence of double (w 1 /o/w 2 ) emulsion composition on lubrication properties
journal, January 2017
- Oppermann, A. K. L.; Verkaaik, L. C.; Stieger, M.
- Food & Function, Vol. 8, Issue 2
W/O/W Multiple Emulsions for Dermatological and Cosmetic Use, Obtained with Ethylene Oxide Free Emulsifiers
journal, March 2005
- Carlotti, M. Eugenia; Gallarate, M.; Sapino, S.
- Journal of Dispersion Science and Technology, Vol. 26, Issue 2
Microencapsulation of Oils: A Comprehensive Review of Benefits, Techniques, and Applications: Encapsulation of marine, vegetable, essential oils…
journal, November 2015
- Bakry, Amr M.; Abbas, Shabbar; Ali, Barkat
- Comprehensive Reviews in Food Science and Food Safety, Vol. 15, Issue 1
Capsules: Their Past and Opportunities for Their Future
journal, July 2017
- Amstad, Esther
- ACS Macro Letters, Vol. 6, Issue 8
Tandem emulsification for high-throughput production of double emulsions
journal, January 2017
- Eggersdorfer, M. L.; Zheng, W.; Nawar, S.
- Lab on a Chip, Vol. 17, Issue 5
Microfluidics-assisted engineering of polymeric microcapsules with high encapsulation efficiency for protein drug delivery
journal, September 2014
- Pessi, Jenni; Santos, Hélder A.; Miroshnyk, Inna
- International Journal of Pharmaceutics, Vol. 472, Issue 1-2
Encapsulation of Resveratrol Using Water-in-Oil-in-Water Double Emulsions
journal, March 2010
- Hemar, Yacine; Cheng, Li Jiang; Oliver, Christine M.
- Food Biophysics, Vol. 5, Issue 2
Robust scalable high throughput production of monodisperse drops
journal, January 2016
- Amstad, E.; Chemama, M.; Eggersdorfer, M.
- Lab on a Chip, Vol. 16, Issue 21
High throughput production of single core double emulsions in a parallelized microfluidic device
journal, January 2012
- Romanowsky, Mark B.; Abate, Adam R.; Rotem, Assaf
- Lab on a Chip, Vol. 12, Issue 4