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Title: Protective effects of mung bean ( Vigna radiata L.) and pea ( Pisum sativum L.) against high‐fat‐induced oxidative stress

Abstract

Abstract Hyperlipidemia is closely related to oxidative stress, and it has been proved that the intake of legumes can protect the body from chronic diseases related to oxidative stress. In this study, we investigated the protective effects of mung beans and peas against high‐fat‐diet‐induced rats. It was found that, with 50% addition of mung beans or peas, the intake of mung beans and peas could significantly restore the levels of serum total cholesterol, low‐density lipoprotein cholesterol, and high‐density lipoprotein cholesterol. Liver staining also showed that high‐fat diet (HFD) led to liver lesions, whereas whole‐grain intake could significantly relieve these symptoms. Compared with the HFD group, the antioxidant defense system and antioxidant gene expression in administered legume groups improved markedly. Furthermore, the antioxidant activities of the two legume extracts were determined. Characterization showed that the ethanol extracts of mung beans and peas possessed high antioxidant activities, for their ability to scavenge ABTS and DPPH, reduce Fe 3+ and their antilipid peroxidation capacity. Treatments with ethanol extracts at different doses could restore the levels of intracellular lipid, malondialdehyde, and antioxidant enzyme activities in oleic acid‐induced HepG2 cells. All these results suggested that mung beans and peas or their extracts may be utilizedmore » as good candidates of natural antioxidant agents.« less

Authors:
 [1]; ORCiD logo [1];  [1];  [1];  [2];  [1];  [1]
  1. School of Medical Instruments and Food Engineering University of Shanghai for Science and Technology Shanghai China
  2. College of Information Engineering Shanghai Maritime University Shanghai China
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1575105
Alternate Identifier(s):
OSTI ID: 1575106
Resource Type:
Published Article
Journal Name:
Food Science and Nutrition
Additional Journal Information:
Journal Name: Food Science and Nutrition Journal Volume: 7 Journal Issue: 12; Journal ID: ISSN 2048-7177
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
United States
Language:
English

Citation Formats

Liu, Dandan, Guan, Xiao, Huang, Kai, Li, Sen, Liu, Jing, Yu, Wenwen, and Duan, Ruiqian. Protective effects of mung bean ( Vigna radiata L.) and pea ( Pisum sativum L.) against high‐fat‐induced oxidative stress. United States: N. p., 2019. Web. doi:10.1002/fsn3.1271.
Liu, Dandan, Guan, Xiao, Huang, Kai, Li, Sen, Liu, Jing, Yu, Wenwen, & Duan, Ruiqian. Protective effects of mung bean ( Vigna radiata L.) and pea ( Pisum sativum L.) against high‐fat‐induced oxidative stress. United States. https://doi.org/10.1002/fsn3.1271
Liu, Dandan, Guan, Xiao, Huang, Kai, Li, Sen, Liu, Jing, Yu, Wenwen, and Duan, Ruiqian. Thu . "Protective effects of mung bean ( Vigna radiata L.) and pea ( Pisum sativum L.) against high‐fat‐induced oxidative stress". United States. https://doi.org/10.1002/fsn3.1271.
@article{osti_1575105,
title = {Protective effects of mung bean ( Vigna radiata L.) and pea ( Pisum sativum L.) against high‐fat‐induced oxidative stress},
author = {Liu, Dandan and Guan, Xiao and Huang, Kai and Li, Sen and Liu, Jing and Yu, Wenwen and Duan, Ruiqian},
abstractNote = {Abstract Hyperlipidemia is closely related to oxidative stress, and it has been proved that the intake of legumes can protect the body from chronic diseases related to oxidative stress. In this study, we investigated the protective effects of mung beans and peas against high‐fat‐diet‐induced rats. It was found that, with 50% addition of mung beans or peas, the intake of mung beans and peas could significantly restore the levels of serum total cholesterol, low‐density lipoprotein cholesterol, and high‐density lipoprotein cholesterol. Liver staining also showed that high‐fat diet (HFD) led to liver lesions, whereas whole‐grain intake could significantly relieve these symptoms. Compared with the HFD group, the antioxidant defense system and antioxidant gene expression in administered legume groups improved markedly. Furthermore, the antioxidant activities of the two legume extracts were determined. Characterization showed that the ethanol extracts of mung beans and peas possessed high antioxidant activities, for their ability to scavenge ABTS and DPPH, reduce Fe 3+ and their antilipid peroxidation capacity. Treatments with ethanol extracts at different doses could restore the levels of intracellular lipid, malondialdehyde, and antioxidant enzyme activities in oleic acid‐induced HepG2 cells. All these results suggested that mung beans and peas or their extracts may be utilized as good candidates of natural antioxidant agents.},
doi = {10.1002/fsn3.1271},
journal = {Food Science and Nutrition},
number = 12,
volume = 7,
place = {United States},
year = {Thu Nov 21 00:00:00 EST 2019},
month = {Thu Nov 21 00:00:00 EST 2019}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1002/fsn3.1271

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Cited by: 5 works
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