Drawing with Iron on a Gel Containing a Supramolecular Siderophore

Xiao, Songjun; Paukstelis, Paul J.; Ash, Richard D.; Zavalij, Peter Y.; Davis, Jeffery T.

doi:10.1002/ange.201910872

Title: Drawing with Iron on a Gel Containing a Supramolecular Siderophore

Journal Article · 04 November 2019 · Angewandte Chemie

DOI: https://doi.org/10.1002/ange.201910872 · OSTI ID:1573078

Xiao, Songjun ^[1]; Paukstelis, Paul J. ^[1]; Ash, Richard D. ^[2]; Zavalij, Peter Y. ^[1];

^[1]

Department of Chemistry and Biochemistry University of Maryland College Park MD 20742 USA
Department of Geology University of Maryland College Park MD 20742 USA

Abstract Guanosine‐5′‐hydroxamic acid ( 3 ) forms hydrogels when mixed with guanosine ( 1 ) and KCl. The 5′‐hydroxamic acid (HA) unit is pH‐responsive and also chelates Fe ³⁺ . When gels are prepared under basic conditions, the 5′‐HA groups are deprotonated and the anionic hydrogel binds cationic thiazole orange (TO), signaled by enhanced fluorescence. The HA nucleoside 3 , when immobilized in the G‐quartet gel, acts as a supramolecular siderophore to form red complexes with Fe ³⁺ . We patterned the hydrogel's surface with FeCl ₃ , by hand and by using a 3D printer. Patterns form instantly, are visible by eye, and can be erased using vitamin C. This hydrogel, combining self‐assembled G‐quartet and siderophore–Fe ³⁺ motifs, is strong, can be molded into different shapes, and is stable on the bench or under salt water.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: NONE; FG02-98ER14888

OSTI ID:: 1573078

Journal Information:: Angewandte Chemie, Journal Name: Angewandte Chemie Journal Issue: 51 Vol. 131; ISSN 0044-8249

Publisher:: Wiley Blackwell (John Wiley & Sons)Copyright Statement

Country of Publication:: Germany

Language:: English

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