Drawing with Iron on a Gel Containing a Supramolecular Siderophore
Abstract
Abstract Guanosine‐5′‐hydroxamic acid ( 3 ) forms hydrogels when mixed with guanosine ( 1 ) and KCl. The 5′‐hydroxamic acid (HA) unit is pH‐responsive and also chelates Fe 3+ . When gels are prepared under basic conditions, the 5′‐HA groups are deprotonated and the anionic hydrogel binds cationic thiazole orange (TO), signaled by enhanced fluorescence. The HA nucleoside 3 , when immobilized in the G‐quartet gel, acts as a supramolecular siderophore to form red complexes with Fe 3+ . We patterned the hydrogel's surface with FeCl 3 , by hand and by using a 3D printer. Patterns form instantly, are visible by eye, and can be erased using vitamin C. This hydrogel, combining self‐assembled G‐quartet and siderophore–Fe 3+ motifs, is strong, can be molded into different shapes, and is stable on the bench or under salt water.
- Authors:
-
[1]
- Univ. of Maryland, College Park, MD (United States). Dept. of Chemistry and Biochemistry
- Univ. of Maryland, College Park, MD (United States). Dept. of Geology
- Publication Date:
- Research Org.:
- Univ. of Maryland, College Park, MD (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1800949
- Alternate Identifier(s):
- OSTI ID: 1573075
- Grant/Contract Number:
- FG02-98ER14888
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Angewandte Chemie (International Edition)
- Additional Journal Information:
- Journal Name: Angewandte Chemie (International Edition); Journal Volume: 58; Journal Issue: 51; Journal ID: ISSN 1433-7851
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; self-assembly; iron; hydroxamic acid; hydrogels; G-quadruplexes
Citation Formats
Xiao, Songjun, Paukstelis, Paul J., Ash, Richard D., Zavalij, Peter Y., and Davis, Jeffery T. Drawing with Iron on a Gel Containing a Supramolecular Siderophore. United States: N. p., 2019.
Web. doi:10.1002/anie.201910872.
Xiao, Songjun, Paukstelis, Paul J., Ash, Richard D., Zavalij, Peter Y., & Davis, Jeffery T. Drawing with Iron on a Gel Containing a Supramolecular Siderophore. United States. https://doi.org/10.1002/anie.201910872
Xiao, Songjun, Paukstelis, Paul J., Ash, Richard D., Zavalij, Peter Y., and Davis, Jeffery T. Wed .
"Drawing with Iron on a Gel Containing a Supramolecular Siderophore". United States. https://doi.org/10.1002/anie.201910872. https://www.osti.gov/servlets/purl/1800949.
@article{osti_1800949,
title = {Drawing with Iron on a Gel Containing a Supramolecular Siderophore},
author = {Xiao, Songjun and Paukstelis, Paul J. and Ash, Richard D. and Zavalij, Peter Y. and Davis, Jeffery T.},
abstractNote = {Abstract Guanosine‐5′‐hydroxamic acid ( 3 ) forms hydrogels when mixed with guanosine ( 1 ) and KCl. The 5′‐hydroxamic acid (HA) unit is pH‐responsive and also chelates Fe 3+ . When gels are prepared under basic conditions, the 5′‐HA groups are deprotonated and the anionic hydrogel binds cationic thiazole orange (TO), signaled by enhanced fluorescence. The HA nucleoside 3 , when immobilized in the G‐quartet gel, acts as a supramolecular siderophore to form red complexes with Fe 3+ . We patterned the hydrogel's surface with FeCl 3 , by hand and by using a 3D printer. Patterns form instantly, are visible by eye, and can be erased using vitamin C. This hydrogel, combining self‐assembled G‐quartet and siderophore–Fe 3+ motifs, is strong, can be molded into different shapes, and is stable on the bench or under salt water.},
doi = {10.1002/anie.201910872},
journal = {Angewandte Chemie (International Edition)},
number = 51,
volume = 58,
place = {United States},
year = {Wed Oct 16 00:00:00 EDT 2019},
month = {Wed Oct 16 00:00:00 EDT 2019}
}
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Works referencing / citing this record:
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