Experiments and computations of microfluidic liquid–liquid flow patterns

Desir, Pierre; Chen, Tai-Ying; Bracconi, Mauro; Saha, Basudeb; Maestri, Matteo; Vlachos, Dionisios G.

doi:10.1039/C9RE00332K

Title: Experiments and computations of microfluidic liquid–liquid flow patterns

Abstract

We study two-phase liquid–liquid flow patterns in a 500 μm capillary microchannel for four biphasic systems: ethyl acetate/water, 2-pentanol/water, methyl isobutyl ketone/water, and heptane/water. Flow visualization experiments using laser induced fluorescence (LIF) reveal a total of 7 different flow patterns for all solvent pairs, namely slug flow, droplet flow, slug-droplet flow, parallel, annular, dispersed, and irregular flow. A map of different flow patterns was built to delineate the origin of their formation. We find conventional dimensionless groups are insufficient to uniquely identify the flow patterns. Computational fluid dynamics (CFD) modeling in OpenFOAM shows agreement with the experimental flow patterns for most of the two-phase flows. Principal component analysis reduces the dimensionality of potential descriptors of flow patterns and, unlike prior work using two dimensionless numbers, determines six important features that describe >95% of the variance of the experimental flow patterns. These include the total flow rate, the flow rate ratio between the two phases, the capillary and Ohnesorge numbers of the aqueous phase, and the Weber number and velocity of the organic phase. Lastly, we build a decision-tree model to further regress the data and identify the critical features and demonstrate an accuracy in predicting the flow patterns of upmore » to 93%.« less

Authors:

Desir, Pierre ^[1]; Chen, Tai-Ying ^[1];

^[2];

^[3];

^[2];

^[4]

Univ. of Delaware, Newark, DE (United States)
Laboratory of Catalysis and Catalytic Processes, Milano (Italy)
Catalysis Center for Energy Innovation, Newark DE (United States)
Univ. of Delaware, Newark, DE (United States); Catalysis Center for Energy Innovation, Newark DE (United States)

Publication Date:: Tue Oct 01 00:00:00 EDT 2019

Research Org.:: RAPID Manufacturing Institute, New York, NY (United States)

Sponsoring Org.:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Energy Efficiency Office. Advanced Manufacturing Office

OSTI Identifier:: 1642397

Alternate Identifier(s):: OSTI ID: 1569773

Grant/Contract Number:: EE0007888

Resource Type:: Accepted Manuscript

Journal Name:: Reaction Chemistry & Engineering

Additional Journal Information:: Journal Volume: 5; Journal Issue: 1; Journal ID: ISSN 2058-9883

Publisher:: Royal Society of Chemistry

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; Biomass; computational fluid dynamics; flow pattern; laser induced fluorescence; machine learning; two-phase flow

Citation Formats


                    Desir, Pierre, Chen, Tai-Ying, Bracconi, Mauro, Saha, Basudeb, Maestri, Matteo, and Vlachos, Dionisios G. Experiments and computations of microfluidic liquid–liquid flow patterns.  United States: N. p., 2019. 
Web.  doi:10.1039/C9RE00332K.

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                    Desir, Pierre, Chen, Tai-Ying, Bracconi, Mauro, Saha, Basudeb, Maestri, Matteo, & Vlachos, Dionisios G. Experiments and computations of microfluidic liquid–liquid flow patterns.  United States.  https://doi.org/10.1039/C9RE00332K

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                    Desir, Pierre, Chen, Tai-Ying, Bracconi, Mauro, Saha, Basudeb, Maestri, Matteo, and Vlachos, Dionisios G. Tue .  
"Experiments and computations of microfluidic liquid–liquid flow patterns".  United States.  https://doi.org/10.1039/C9RE00332K.  https://www.osti.gov/servlets/purl/1642397.

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@article{osti_1642397,

  title        = {Experiments and computations of microfluidic liquid–liquid flow patterns},

  author       = {Desir, Pierre and Chen, Tai-Ying and Bracconi, Mauro and Saha, Basudeb and Maestri, Matteo and Vlachos, Dionisios G.},

  abstractNote = {We study two-phase liquid–liquid flow patterns in a 500 μm capillary microchannel for four biphasic systems: ethyl acetate/water, 2-pentanol/water, methyl isobutyl ketone/water, and heptane/water. Flow visualization experiments using laser induced fluorescence (LIF) reveal a total of 7 different flow patterns for all solvent pairs, namely slug flow, droplet flow, slug-droplet flow, parallel, annular, dispersed, and irregular flow. A map of different flow patterns was built to delineate the origin of their formation. We find conventional dimensionless groups are insufficient to uniquely identify the flow patterns. Computational fluid dynamics (CFD) modeling in OpenFOAM shows agreement with the experimental flow patterns for most of the two-phase flows. Principal component analysis reduces the dimensionality of potential descriptors of flow patterns and, unlike prior work using two dimensionless numbers, determines six important features that describe >95% of the variance of the experimental flow patterns. These include the total flow rate, the flow rate ratio between the two phases, the capillary and Ohnesorge numbers of the aqueous phase, and the Weber number and velocity of the organic phase. Lastly, we build a decision-tree model to further regress the data and identify the critical features and demonstrate an accuracy in predicting the flow patterns of up to 93%.},

  doi          = {10.1039/C9RE00332K},

  journal      = {Reaction Chemistry & Engineering},

  number       = 1,

  volume       = 5,

  place        = {United States},

  year         = {Tue Oct 01 00:00:00 EDT 2019},

  month        = {Tue Oct 01 00:00:00 EDT 2019}

}

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Works referenced in this record:

Liquid-liquid two-phase flow patterns in a rectangular microchannel
journal, January 2006

Zhao, Yuchao; Chen, Guangwen; Yuan, Quan
AIChE Journal, Vol. 52, Issue 12
DOI: 10.1002/aic.11029

Interfacial stabilization of organic–aqueous two-phase microflows for a miniaturized DNA extraction module
journal, June 2005

Reddy, Varun; Zahn, Jeffrey D.
Journal of Colloid and Interface Science, Vol. 286, Issue 1
DOI: 10.1016/j.jcis.2004.12.052

An Integrated Nanoliter DNA Analysis Device
journal, October 1998

Burns, M. A.
Science, Vol. 282, Issue 5388
DOI: 10.1126/science.282.5388.484

Hydrodynamic studies of liquid–liquid slug flows in circular microchannels
journal, March 2011

Ghaini, Aras; Mescher, Axel; Agar, David W.
Chemical Engineering Science, Vol. 66, Issue 6
DOI: 10.1016/j.ces.2010.12.033

Microfluidic methods for generating continuous droplet streams
journal, September 2007

Christopher, G. F.; Anna, S. L.
Journal of Physics D: Applied Physics, Vol. 40, Issue 19
DOI: 10.1088/0022-3727/40/19/R01

Numerical study on gas and liquid slugs for Taylor flow in a T-junction microchannel
journal, December 2006

Qian, Dongying; Lawal, Adeniyi
Chemical Engineering Science, Vol. 61, Issue 23
DOI: 10.1016/j.ces.2006.08.073

On-Chip Integration of Neutral Ionophore-Based Ion Pair Extraction Reaction
journal, March 2001

Hisamoto, Hideaki; Horiuchi, Takayuki; Tokeshi, Manabu
Analytical Chemistry, Vol. 73, Issue 6
DOI: 10.1021/ac001271v

Volume-of-fluid simulations in microfluidic T-junction devices: Influence of viscosity ratio on droplet size
journal, March 2017

Nekouei, Mehdi; Vanapalli, Siva A.
Physics of Fluids, Vol. 29, Issue 3
DOI: 10.1063/1.4978801

Formation of dispersions using “flow focusing” in microchannels
journal, January 2003

Anna, Shelley L.; Bontoux, Nathalie; Stone, Howard A.
Applied Physics Letters, Vol. 82, Issue 3
DOI: 10.1063/1.1537519

Process Intensification of Biodiesel Production Using a Tubular Micro-Reactor (TMR): Experimental and Numerical Assessment
journal, December 2016

López-Guajardo, Enrique; Ortiz-Nadal, Enrique; Montesinos-Castellanos, Alejandro
Chemical Engineering Communications, Vol. 204, Issue 4
DOI: 10.1080/00986445.2016.1277521

Kinetic study of hydrogen peroxide decomposition at high temperatures and concentrations in two capillary microreactors
journal, July 2016

Shang, Minjing; Noël, Timothy; Su, Yuanhai
AIChE Journal, Vol. 63, Issue 2
DOI: 10.1002/aic.15385

Scalability of mass transfer in liquid–liquid flow
journal, September 2014

Woitalka, A.; Kuhn, S.; Jensen, K. F.
Chemical Engineering Science, Vol. 116
DOI: 10.1016/j.ces.2014.04.036

Interfacial Tension of Alkane + Water Systems ^†
journal, September 2001

Zeppieri, Susana; Rodríguez, Jhosgre; López de Ramos, A. L.
Journal of Chemical & Engineering Data, Vol. 46, Issue 5
DOI: 10.1021/je000245r

Prediction of Liquid–Liquid Flow Patterns in a Y-Junction Circular Microchannel Using Advanced Neural Network Techniques
journal, October 2016

Giri Nandagopal, M. S.; Selvaraju, N.
Industrial & Engineering Chemistry Research, Vol. 55, Issue 43
DOI: 10.1021/acs.iecr.6b02438

Size control of calcium alginate beads containing living cells using micro-nozzle array
journal, June 2005

Sugiura, Shinji; Oda, Tatsuya; Izumida, Yasuhiko
Biomaterials, Vol. 26, Issue 16
DOI: 10.1016/j.biomaterials.2004.08.029

Random Forests for mapping and analysis of microkinetics models
journal, July 2018

Partopour, Behnam; Paffenroth, Randy C.; Dixon, Anthony G.
Computers & Chemical Engineering, Vol. 115
DOI: 10.1016/j.compchemeng.2018.04.019

A systematic analysis of performance measures for classification tasks
journal, July 2009

Sokolova, Marina; Lapalme, Guy
Information Processing & Management, Vol. 45, Issue 4
DOI: 10.1016/j.ipm.2009.03.002

ANN-based prediction of two-phase gas- liquid flow patterns in a circular conduit
journal, September 2006

Sharma, H.; Das, G.; Samanta, A. N.
AIChE Journal, Vol. 52, Issue 9
DOI: 10.1002/aic.10922

A Continuous-Flow Microcapillary Reactor for the Preparation of a Size Series of CdSe Nanocrystals
journal, November 2003

Yen, B. K. H.; Stott, N. E.; Jensen, K. F.
Advanced Materials, Vol. 15, Issue 21
DOI: 10.1002/adma.200305162

Numerical Study on Bubble Formation of a Gas-Liquid Flow in a T-Junction Microchannel
journal, December 2009

Dai, L.; Cai, W.; Xin, F.
Chemical Engineering & Technology, Vol. 32, Issue 12
DOI: 10.1002/ceat.200900351

Distribution of Methyl red on the Water–Organic Liquid Interface in a Microchannel
journal, June 2001

Surmeian, Mariana; Hibara, A.; Slyadnev, M.
Analytical Letters, Vol. 34, Issue 9
DOI: 10.1081/AL-100104916

Volume-of-Fluid Interface Tracking with Smoothed Surface Stress Methods for Three-Dimensional Flows
journal, July 1999

Gueyffier, Denis; Li, Jie; Nadim, Ali
Journal of Computational Physics, Vol. 152, Issue 2
DOI: 10.1006/jcph.1998.6168

A continuum method for modeling surface tension
journal, June 1992

Brackbill, J. U.; Kothe, D. B.; Zemach, C.
Journal of Computational Physics, Vol. 100, Issue 2
DOI: 10.1016/0021-9991(92)90240-Y

Micro wet analysis system using multi-phase laminar flows in three-dimensional microchannel networkElectronic supplementary information (ESI) available: illustration and microscopic view of two-phase laminar flow. See http://www.rsc.org/suppdata/lc/b4/b400233d/
journal, January 2004

Kikutani, Yoshikuni; Hisamoto, Hideaki; Tokeshi, Manabu
Lab on a Chip, Vol. 4, Issue 4
DOI: 10.1039/b400233d

OpenFOAM Computational Fluid Dynamic Simulations of Two-Phase Flow and Mass Transfer in an Advanced-Flow Reactor
journal, June 2015

Nieves-Remacha, María José; Yang, Lu; Jensen, Klavs F.
Industrial & Engineering Chemistry Research, Vol. 54, Issue 26
DOI: 10.1021/acs.iecr.5b00480

Simulations and analysis of multiphase transport and reaction in segmented flow microreactors
journal, September 2017

Yang, Lu; Nieves-Remacha, Maria Jose; Jensen, Klavs F.
Chemical Engineering Science, Vol. 169
DOI: 10.1016/j.ces.2016.12.003

An Introduction to Statistical Learning
book, January 2013

James, Gareth; Witten, Daniela; Hastie, Trevor
Springer Texts in Statistics
DOI: 10.1007/978-1-4614-7138-7

Liquid–Liquid Two-Phase Flow Patterns in Y-Junction Microchannels
journal, October 2017

Darekar, Mayur; Singh, Krishna Kumar; Mukhopadhyay, Sulekha
Industrial & Engineering Chemistry Research, Vol. 56, Issue 42
DOI: 10.1021/acs.iecr.7b03164

Advanced neural network prediction and system identification of liquid-liquid flow patterns in circular microchannels with varying angle of confluence
journal, February 2017

Nandagopal, M. S. Giri; Abraham, Eldho; Selvaraju, N.
Chemical Engineering Journal, Vol. 309
DOI: 10.1016/j.cej.2016.10.106

Flow patterns of immiscible liquid-liquid flow in a rectangular microchannel with T-junction
journal, November 2016

Yagodnitsyna, Anna A.; Kovalev, Alexander V.; Bilsky, Artur V.
Chemical Engineering Journal, Vol. 303
DOI: 10.1016/j.cej.2016.06.023

Liquid–Liquid Flow in a Capillary Microreactor: Hydrodynamic Flow Patterns and Extraction Performance
journal, June 2011

Jovanović, Jovan; Rebrov, Evgeny V.; Nijhuis, T. A. (Xander)
Industrial & Engineering Chemistry Research, Vol. 51, Issue 2
DOI: 10.1021/ie200715m

The Elements of Statistical Learning
book, January 2009

Hastie, Trevor; Tibshirani, Robert; Friedman, Jerome
Springer Series in Statistics
DOI: 10.1007/978-0-387-84858-7

Drop impact onto a liquid layer of finite thickness: Dynamics of the cavity evolution
journal, March 2009

Berberović, Edin; van Hinsberg, Nils P.; Jakirlić, Suad
Physical Review E, Vol. 79, Issue 3
DOI: 10.1103/PhysRevE.79.036306

Benchmark numerical simulations of segmented two-phase flows in microchannels using the Volume of Fluid method
journal, November 2013

Hoang, Duong A.; van Steijn, Volkert; Portela, Luis M.
Computers & Fluids, Vol. 86
DOI: 10.1016/j.compfluid.2013.06.024

Transition from squeezing to dripping in a microfluidic T-shaped junction
journal, January 2008

De Menech, M.; Garstecki, P.; Jousse, F.
Journal of Fluid Mechanics, Vol. 595
DOI: 10.1017/S002211200700910X

Liquid–liquid two-phase flow patterns and mass transfer characteristics in rectangular glass microreactors
journal, August 2008

Dessimoz, Anne-Laure; Cavin, Laurent; Renken, Albert
Chemical Engineering Science, Vol. 63, Issue 16
DOI: 10.1016/j.ces.2008.05.005

Microfluidic Droplet-Based Liquid−Liquid Extraction
journal, April 2008

Mary, Pascaline; Studer, Vincent; Tabeling, Patrick
Analytical Chemistry, Vol. 80, Issue 8
DOI: 10.1021/ac800088s

Effective interfacial area for mass transfer in the liquid–liquid slug flow capillary microreactors
journal, April 2010

Ghaini, A.; Kashid, M. N.; Agar, D. W.
Chemical Engineering and Processing: Process Intensification, Vol. 49, Issue 4
DOI: 10.1016/j.cep.2010.03.009

Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up
journal, January 2006

Garstecki, Piotr; Fuerstman, Michael J.; Stone, Howard A.
Lab on a Chip, Vol. 6, Issue 3
DOI: 10.1039/b510841a

Flow patterns and pressure drop of ionic liquid–water two-phase flows in microchannels
journal, September 2013

Tsaoulidis, Dimitrios; Dore, Valentina; Angeli, Panagiota
International Journal of Multiphase Flow, Vol. 54
DOI: 10.1016/j.ijmultiphaseflow.2013.02.002

Two-phase microfluidic flows
journal, April 2011

Zhao, Chun-Xia; Middelberg, Anton P. J.
Chemical Engineering Science, Vol. 66, Issue 7
DOI: 10.1016/j.ces.2010.08.038

A tensorial approach to computational continuum mechanics using object-oriented techniques
journal, January 1998

Weller, H. G.; Tabor, G.; Jasak, H.
Computers in Physics, Vol. 12, Issue 6
DOI: 10.1063/1.168744

Volume of fluid (VOF) method for the dynamics of free boundaries
journal, January 1981

Hirt, C. W.; Nichols, B. D.
Journal of Computational Physics, Vol. 39, Issue 1
DOI: 10.1016/0021-9991(81)90145-5

Liquid–liquid microflow reaction engineering
journal, January 2017

Wang, Kai; Li, Liantang; Xie, Pei
Reaction Chemistry & Engineering, Vol. 2, Issue 5
DOI: 10.1039/C7RE00082K

Effect of channel size on mass transfer during liquid–liquid plug flow in small scale extractors
journal, February 2015

Tsaoulidis, Dimitrios; Angeli, Panagiota
Chemical Engineering Journal, Vol. 262
DOI: 10.1016/j.cej.2014.10.012

Experimental investigation of liquid–liquid mixing in T-shaped micro-mixers using <mml:math altimg="si31.gif" display="inline" overflow="scroll" xmlns:xocs="http://www.elsevier.com/xml/xocs/dtd" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.elsevier.com/xml/ja/dtd" xmlns:ja="http://www.elsevier.com/xml/ja/dtd" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:tb="http://www.elsevier.com/xml/common/table/dtd" xmlns:sb="http://www.elsevier.com/xml/common/struct-bib/dtd" xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:cals="http://www.elsevier.com/xml/common/cals/dtd"><mml:mi mathvariant="normal">μ</mml:mi></mml:math>-LIF and <mml:math altimg="si32.gif" display="inline" overflow="scroll" xmlns:xocs="http://www.elsevier.com/xml/xocs/dtd" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.elsevier.com/xml/ja/dtd" xmlns:ja="http://www.elsevier.com/xml/ja/dtd" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:tb="http://www.elsevier.com/xml/common/table/dtd" xmlns:sb="http://www.elsevier.com/xml/common/struct-bib/dtd" xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:cals="http://www.elsevier.com/xml/common/cals/dtd"><mml:mi mathvariant="normal">μ</mml:mi></mml:math>-PIV
journal, May 2006

Hoffmann, Marko; Schlüter, Michael; Räbiger, Norbert
Chemical Engineering Science, Vol. 61, Issue 9
DOI: 10.1016/j.ces.2005.11.029

Membrane-Based, Liquid–Liquid Separator with Integrated Pressure Control
journal, July 2013

Adamo, Andrea; Heider, Patrick L.; Weeranoppanant, Nopphon
Industrial & Engineering Chemistry Research, Vol. 52, Issue 31
DOI: 10.1021/ie401180t

Continuous Micro Liquid-Liquid Extraction
journal, April 2013

Assmann, N.; Ładosz, A.; Rudolf von Rohr, P.
Chemical Engineering & Technology, Vol. 36, Issue 6
DOI: 10.1002/ceat.201200557

Liquid−Liquid Slug Flow in a Capillary: An Alternative to Suspended Drop or Film Contactors
journal, December 2007

Kashid, M. N.; Harshe, Y. M.; Agar, D. W.
Industrial & Engineering Chemistry Research, Vol. 46, Issue 25
DOI: 10.1021/ie070077x

Hydrodynamics of liquid–liquid slug flow capillary microreactor: Flow regimes, slug size and pressure drop
journal, July 2007

Kashid, Madhvanand N.; Agar, David W.
Chemical Engineering Journal, Vol. 131, Issue 1-3
DOI: 10.1016/j.cej.2006.11.020

Initial Interfacial Tension for Various Organic–Water Systems and Study of the Effect of Solute Concentration and Temperature
journal, March 2017

Shahid, Muhammad Zubair; Usman, Muhammad Rashid; Akram, Muhammad Sarfraz
Journal of Chemical & Engineering Data, Vol. 62, Issue 4
DOI: 10.1021/acs.jced.6b00703

Data science: Accelerating innovation and discovery in chemical engineering
journal, February 2016

Beck, David A. C.; Carothers, James M.; Subramanian, Venkat R.
AIChE Journal, Vol. 62, Issue 5
DOI: 10.1002/aic.15192

Continuous 5-Hydroxymethylfurfural Production from Monosaccharides in a Microreactor
journal, September 2017

Muranaka, Yosuke; Nakagawa, Hiroyuki; Masaki, Rie
Industrial & Engineering Chemistry Research, Vol. 56, Issue 39
DOI: 10.1021/acs.iecr.7b02017

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journal, March 2021

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DOI: 10.1007/s10278-021-00442-5

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journal, January 2021

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Scientific Reports, Vol. 11, Issue 1
DOI: 10.1038/s41598-020-79947-y

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text, January 2003

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Carnegie Mellon University
DOI: 10.1184/r1/6466991

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DOI: 10.1184/r1/6466991.v1

The Elements of Statistical Learning
book, January 2001

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DOI: 10.1007/978-0-387-21606-5

Volume-of-fluid simulations in microfluidic T-junction devices: Influence of viscosity ratio on droplet size
text, January 2017

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arXiv
DOI: 10.48550/arxiv.1703.00937

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Title: Experiments and computations of microfluidic liquid–liquid flow patterns

Abstract

Citation Formats

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Interfacial stabilization of organic–aqueous two-phase microflows for a miniaturized DNA extraction module journal, June 2005

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journal, November 2003

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journal, December 2009

Distribution of Methyl red on the Water–Organic Liquid Interface in a Microchannel
journal, June 2001

Volume-of-Fluid Interface Tracking with Smoothed Surface Stress Methods for Three-Dimensional Flows
journal, July 1999

A continuum method for modeling surface tension
journal, June 1992

Micro wet analysis system using multi-phase laminar flows in three-dimensional microchannel networkElectronic supplementary information (ESI) available: illustration and microscopic view of two-phase laminar flow. See http://www.rsc.org/suppdata/lc/b4/b400233d/
journal, January 2004

OpenFOAM Computational Fluid Dynamic Simulations of Two-Phase Flow and Mass Transfer in an Advanced-Flow Reactor
journal, June 2015

Simulations and analysis of multiphase transport and reaction in segmented flow microreactors
journal, September 2017

An Introduction to Statistical Learning
book, January 2013

Liquid–Liquid Two-Phase Flow Patterns in Y-Junction Microchannels
journal, October 2017

Advanced neural network prediction and system identification of liquid-liquid flow patterns in circular microchannels with varying angle of confluence
journal, February 2017

Flow patterns of immiscible liquid-liquid flow in a rectangular microchannel with T-junction
journal, November 2016

Liquid–Liquid Flow in a Capillary Microreactor: Hydrodynamic Flow Patterns and Extraction Performance
journal, June 2011

The Elements of Statistical Learning
book, January 2009

Drop impact onto a liquid layer of finite thickness: Dynamics of the cavity evolution
journal, March 2009

Benchmark numerical simulations of segmented two-phase flows in microchannels using the Volume of Fluid method
journal, November 2013

Transition from squeezing to dripping in a microfluidic T-shaped junction
journal, January 2008

Liquid–liquid two-phase flow patterns and mass transfer characteristics in rectangular glass microreactors
journal, August 2008

Microfluidic Droplet-Based Liquid−Liquid Extraction
journal, April 2008

Effective interfacial area for mass transfer in the liquid–liquid slug flow capillary microreactors
journal, April 2010

Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up
journal, January 2006

Flow patterns and pressure drop of ionic liquid–water two-phase flows in microchannels
journal, September 2013

Two-phase microfluidic flows
journal, April 2011

A tensorial approach to computational continuum mechanics using object-oriented techniques
journal, January 1998

Volume of fluid (VOF) method for the dynamics of free boundaries
journal, January 1981

Liquid–liquid microflow reaction engineering
journal, January 2017

Effect of channel size on mass transfer during liquid–liquid plug flow in small scale extractors
journal, February 2015

Membrane-Based, Liquid–Liquid Separator with Integrated Pressure Control
journal, July 2013

Continuous Micro Liquid-Liquid Extraction
journal, April 2013

Liquid−Liquid Slug Flow in a Capillary: An Alternative to Suspended Drop or Film Contactors
journal, December 2007

Hydrodynamics of liquid–liquid slug flow capillary microreactor: Flow regimes, slug size and pressure drop
journal, July 2007

Initial Interfacial Tension for Various Organic–Water Systems and Study of the Effect of Solute Concentration and Temperature
journal, March 2017

Data science: Accelerating innovation and discovery in chemical engineering
journal, February 2016

Continuous 5-Hydroxymethylfurfural Production from Monosaccharides in a Microreactor
journal, September 2017

HER2 Molecular Marker Scoring Using Transfer Learning and Decision Level Fusion
journal, March 2021

Optimization of probiotic therapeutics using machine learning in an artificial human gastrointestinal tract
journal, January 2021

Formation of dispersions using ‘‘flow focusing’’ in microchannels
text, January 2003

Formation of dispersions using ‘‘flow focusing’’ in microchannels
text, January 2003

The Elements of Statistical Learning
book, January 2001

Volume-of-fluid simulations in microfluidic T-junction devices: Influence of viscosity ratio on droplet size
text, January 2017