Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging

doi:10.1002/smll.201903382

Title: Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging

Authors:

Zhang, Qing ^[1]; Zhou, Huijun ^[2]; Chen, Hao ^[3]; Zhang, Xiao ^[3]; He, Shuqing ^[3]; Ma, Lina ^[4]; Qu, Chunrong ^[3]; Fang, Wei ^[3]; Han, Yanjiang ^[3]; Wang, Da ^[5]; Huang, Yuanjian ^[6]; Sun, Yueming ^[6]; Fan, Quli ^[7]; Chen, Yue ^[8];

^[3]

Molecular Imaging Program at Stanford (MIPS)Canary Center at Stanford for Cancer Early DetectionDepartment of Radiology and Bio‐X ProgramSchool of MedicineStanford University Stanford CA 94305‐5484 USA, Department of PharmaceuticsSchool of PharmacyNanjing Medical University Nanjing 211166 China
Molecular Imaging Program at Stanford (MIPS)Canary Center at Stanford for Cancer Early DetectionDepartment of Radiology and Bio‐X ProgramSchool of MedicineStanford University Stanford CA 94305‐5484 USA, Department of Nuclear MedicineWest China HospitalSichuan University Chengdu 610041 China
Molecular Imaging Program at Stanford (MIPS)Canary Center at Stanford for Cancer Early DetectionDepartment of Radiology and Bio‐X ProgramSchool of MedicineStanford University Stanford CA 94305‐5484 USA
Molecular Imaging Program at Stanford (MIPS)Canary Center at Stanford for Cancer Early DetectionDepartment of Radiology and Bio‐X ProgramSchool of MedicineStanford University Stanford CA 94305‐5484 USA, State Key Laboratory of Electroanalytical ChemistryChangchun Institute of Applied ChemistryChinese Academy of Sciences Changchun 130022 China
Department of PharmaceuticsSchool of PharmacyNanjing Medical University Nanjing 211166 China
Department of Colorectal SurgeryThe First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China
Key Laboratory for Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials (IAM)Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM)Nanjing University of Posts and Telecommunications Nanjing 210023 China
Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan ProvinceDepartment of Nuclear MedicineThe Affiliated Hospital of Southwest Medical University Luzhou 646000 China

Publication Date:: 2019-09-24

Sponsoring Org.:: USDOE

OSTI Identifier:: 1566189

Grant/Contract Number:: DE‐SC0008397

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Small

Additional Journal Information:: Journal Name: Small Journal Volume: 15 Journal Issue: 45; Journal ID: ISSN 1613-6810

Publisher:: Wiley Blackwell (John Wiley & Sons)

Country of Publication:: Germany

Language:: English

Citation Formats


                    Zhang, Qing, Zhou, Huijun, Chen, Hao, Zhang, Xiao, He, Shuqing, Ma, Lina, Qu, Chunrong, Fang, Wei, Han, Yanjiang, Wang, Da, Huang, Yuanjian, Sun, Yueming, Fan, Quli, Chen, Yue, and Cheng, Zhen. Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging.  Germany: N. p., 2019. 
        Web.  doi:10.1002/smll.201903382.

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                    Zhang, Qing, Zhou, Huijun, Chen, Hao, Zhang, Xiao, He, Shuqing, Ma, Lina, Qu, Chunrong, Fang, Wei, Han, Yanjiang, Wang, Da, Huang, Yuanjian, Sun, Yueming, Fan, Quli, Chen, Yue, & Cheng, Zhen. Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging.  Germany.  doi:10.1002/smll.201903382.

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                    Zhang, Qing, Zhou, Huijun, Chen, Hao, Zhang, Xiao, He, Shuqing, Ma, Lina, Qu, Chunrong, Fang, Wei, Han, Yanjiang, Wang, Da, Huang, Yuanjian, Sun, Yueming, Fan, Quli, Chen, Yue, and Cheng, Zhen. Tue .  
        "Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging".  Germany.  doi:10.1002/smll.201903382.

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@article{osti_1566189,

  title        = {Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging},

  author       = {Zhang, Qing and Zhou, Huijun and Chen, Hao and Zhang, Xiao and He, Shuqing and Ma, Lina and Qu, Chunrong and Fang, Wei and Han, Yanjiang and Wang, Da and Huang, Yuanjian and Sun, Yueming and Fan, Quli and Chen, Yue and Cheng, Zhen},

  abstractNote = {},

  doi          = {10.1002/smll.201903382},

  journal      = {Small},

  number       = 45,

  volume       = 15,

  place        = {Germany},

  year         = {2019},

  month        = {9}

}

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DOI: 10.1002/smll.201903382

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Title: Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image‐Guided Surgery via NIR‐II Fluorescence and PET Bimodal Imaging

Citation Formats

Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells journal, July 2016

Multifunctional Biomedical Imaging in Physiological and Pathological Conditions Using a NIR-II Probe journal, April 2017

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A new near-infrared persistent luminescence nanoparticle as a multifunctional nanoplatform for multimodal imaging and cancer therapy journal, January 2018

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journal, July 2016

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journal, April 2017

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journal, December 2016

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journal, May 2017

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journal, January 2019

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journal, July 2010

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journal, December 2018

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journal, January 2019

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journal, January 2019

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journal, October 2016

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journal, March 2019

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journal, January 2017

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Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles
journal, March 2012

In vivo real-time visualization of tissue blood flow and angiogenesis using Ag2S quantum dots in the NIR-II window
journal, January 2014

A new near-infrared persistent luminescence nanoparticle as a multifunctional nanoplatform for multimodal imaging and cancer therapy
journal, January 2018

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery
journal, January 2018

Optical molecular imaging for tumor detection and image-guided surgery
journal, March 2018

Organic Semiconducting Agents for Deep-Tissue Molecular Imaging: Second Near-Infrared Fluorescence, Self-Luminescence, and Photoacoustics
journal, July 2018

Optical nano-agents in the second near-infrared window for biomedical applications
journal, January 2019

Bright Aggregation-Induced-Emission Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumors
journal, May 2018

Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics
journal, January 2018

Multiple Core−Shell Functionalized Colloidal Mesoporous Silica Nanoparticles
journal, August 2009

Dragon fruit-like biocage as an iron trapping nanoplatform for high efficiency targeted cancer multimodality imaging
journal, November 2015

A small-molecule dye for NIR-II imaging
journal, November 2015

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
journal, April 2011

Biological Imaging Using Nanoparticles of Small Organic Molecules with Fluorescence Emission at Wavelengths Longer than 1000 nm
journal, October 2013

A surface-grafted ligand functionalization strategy for coordinate binding of doxorubicin at surface of PEGylated mesoporous silica nanoparticles: Toward pH-responsive drug delivery
journal, January 2017

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression
journal, August 2014

J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy
journal, January 2018

Transferring Biomarker into Molecular Probe: Melanin Nanoparticle as a Naturally Active Platform for Multimodality Imaging
journal, October 2014

Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer
journal, January 2016

Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer
journal, January 2016

Nanomaterials for In Vivo Imaging
journal, January 2017

Near-infrared fluorophores for biomedical imaging
journal, January 2017

Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy
journal, January 2019

Intranuclear Photosensitizer Delivery and Photosensitization for Enhanced Photodynamic Therapy with Ultralow Irradiance
journal, September 2014