Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling

Journal Article · 31 July 2018 · Cell Systems

DOI: https://doi.org/10.1016/j.cels.2018.06.002 · OSTI ID:1564483

Rukhlenko, Oleksii S.; Khorsand, Fahimeh; Krstic, Aleksandar; Rozanc, Jan; Alexopoulos, Leonidas G.; Rauch, Nora; Erickson, Keesha E.; Hlavacek, William S.; Posner, Richard G.; Gómez-Coca, Silvia; Rosta, Edina; Fitzgibbon, Cheree; Matallanas, David; Rauch, Jens; Kolch, Walter; Kholodenko, Boris N.

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• Research Organization: Los Alamos National Laboratory (LANL)
• Sponsoring Organization: USDOE; USDOE Office of Science (SC). Biological and Environmental Research (BER) (SC-23)
• Grant/Contract Number: AC52-06NA25396
• OSTI ID: 1564483
• Report Number(s): LA-UR-18-26812; S2405471218302424; PII: S2405471218302424
• Journal Information: Cell Systems, Journal Name: Cell Systems Journal Issue: 2 Vol. 7; ISSN 2405-4712
• Publisher: ElsevierCopyright Statement
• Country of Publication: Niger
• Language: English