Adult height, body mass index change, and body shape change in relation to esophageal squamous cell carcinoma risk: A population‐based case‐control study in China
Abstract
Abstract The relationship between risk of esophageal squamous cell carcinoma (ESCC) and adult height, changes in individual body mass index (BMI) and body shape is not established. We performed a large population‐based case‐control study, which enrolled a total of 1414 ESCC cases and 1989 controls in a high‐incidence area in China. Using face‐to‐face interview with a structured questionnaire, information on participants' heights, weights, and perceived body shapes at 20 years of age was collected. Additionally, data on weight and perceived body shape among the same participants 10 years prior to ascertainment were collected using the same method. Odd ratios (ORs) of ESCC risk in relation to BMI and body shape were estimated using unconditional logistic regression models. The adjusted results indicated that ESCC risk in adults rapidly rose as height increased, plateauing at 170 cm among men and 157 cm among women. Among participants who were underweight, normal weight, or thinner than body shape 4, body weight loss was associated with increased risk of ESCC, and body weight gain was associated with decreased incidence of ESCC (ORs ranging from 0.40 to 0.76). Notably, however, changes in body weight did not significantly affect ESCC risk among participants who were overweight, obese, or larger than bodymore »
- Authors:
-
- Clinical Epidemiology Unit Qilu Hospital of Shandong University Jinan China
- Department of Epidemiology and Health Statistics, School of Public Health Shandong University Jinan China
- Fudan University Taizhou Institute of Health Sciences Taizhou China
- Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden
- Fudan University Taizhou Institute of Health Sciences Taizhou China, State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences Fudan University Shanghai China
- Clinical Epidemiology Unit Qilu Hospital of Shandong University Jinan China, Department of Epidemiology and Health Statistics, School of Public Health Shandong University Jinan China, Fudan University Taizhou Institute of Health Sciences Taizhou China
- Fudan University Taizhou Institute of Health Sciences Taizhou China, Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden
- Publication Date:
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1562161
- Alternate Identifier(s):
- OSTI ID: 1562162
- Resource Type:
- Published Article
- Journal Name:
- Cancer medicine
- Additional Journal Information:
- Journal Name: Cancer medicine Journal Volume: 8 Journal Issue: 12; Journal ID: ISSN 2045-7634
- Publisher:
- Wiley Blackwell (John Wiley & Sons)
- Country of Publication:
- United Kingdom
- Language:
- English
Citation Formats
Yang, Xiaorong, Zhang, Tongchao, Yin, Xiaolin, Yuan, Ziyu, Chen, Hui, Plymoth, Amelie, Jin, Li, Chen, Xingdong, Lu, Ming, and Ye, Weimin. Adult height, body mass index change, and body shape change in relation to esophageal squamous cell carcinoma risk: A population‐based case‐control study in China. United Kingdom: N. p., 2019.
Web. doi:10.1002/cam4.2444.
Yang, Xiaorong, Zhang, Tongchao, Yin, Xiaolin, Yuan, Ziyu, Chen, Hui, Plymoth, Amelie, Jin, Li, Chen, Xingdong, Lu, Ming, & Ye, Weimin. Adult height, body mass index change, and body shape change in relation to esophageal squamous cell carcinoma risk: A population‐based case‐control study in China. United Kingdom. https://doi.org/10.1002/cam4.2444
Yang, Xiaorong, Zhang, Tongchao, Yin, Xiaolin, Yuan, Ziyu, Chen, Hui, Plymoth, Amelie, Jin, Li, Chen, Xingdong, Lu, Ming, and Ye, Weimin. Thu .
"Adult height, body mass index change, and body shape change in relation to esophageal squamous cell carcinoma risk: A population‐based case‐control study in China". United Kingdom. https://doi.org/10.1002/cam4.2444.
@article{osti_1562161,
title = {Adult height, body mass index change, and body shape change in relation to esophageal squamous cell carcinoma risk: A population‐based case‐control study in China},
author = {Yang, Xiaorong and Zhang, Tongchao and Yin, Xiaolin and Yuan, Ziyu and Chen, Hui and Plymoth, Amelie and Jin, Li and Chen, Xingdong and Lu, Ming and Ye, Weimin},
abstractNote = {Abstract The relationship between risk of esophageal squamous cell carcinoma (ESCC) and adult height, changes in individual body mass index (BMI) and body shape is not established. We performed a large population‐based case‐control study, which enrolled a total of 1414 ESCC cases and 1989 controls in a high‐incidence area in China. Using face‐to‐face interview with a structured questionnaire, information on participants' heights, weights, and perceived body shapes at 20 years of age was collected. Additionally, data on weight and perceived body shape among the same participants 10 years prior to ascertainment were collected using the same method. Odd ratios (ORs) of ESCC risk in relation to BMI and body shape were estimated using unconditional logistic regression models. The adjusted results indicated that ESCC risk in adults rapidly rose as height increased, plateauing at 170 cm among men and 157 cm among women. Among participants who were underweight, normal weight, or thinner than body shape 4, body weight loss was associated with increased risk of ESCC, and body weight gain was associated with decreased incidence of ESCC (ORs ranging from 0.40 to 0.76). Notably, however, changes in body weight did not significantly affect ESCC risk among participants who were overweight, obese, or larger than body shape 3. Maintaining a fit body shape and a reasonable BMI is advisable and of vital importance to reduce the risk of ESCC, especially in high‐risk areas.},
doi = {10.1002/cam4.2444},
journal = {Cancer medicine},
number = 12,
volume = 8,
place = {United Kingdom},
year = {Thu Aug 01 00:00:00 EDT 2019},
month = {Thu Aug 01 00:00:00 EDT 2019}
}
https://doi.org/10.1002/cam4.2444
Web of Science
Works referenced in this record:
Trajectory of body shape across the lifespan and cancer risk: Trajectory of body shape and cancer risk
journal, February 2016
- Song, Mingyang; Willett, Walter C.; Hu, Frank B.
- International Journal of Cancer, Vol. 138, Issue 10
Leanness and squamous cell oesophageal cancer
journal, July 2001
- Gallus, S.; La Vecchia, C.; Levi, F.
- Annals of Oncology, Vol. 12, Issue 7
Body mass index change during adulthood and risk of oesophageal squamous-cell carcinoma in a Japanese population: the Japan Public Health (JPHC)-based prospective study
journal, September 2017
- Song, Huan; Saito, Eiko; Sawada, Norie
- British Journal of Cancer, Vol. 117, Issue 11
Body Mass Index and Risk of Adenocarcinomas of the Esophagus and Gastric Cardia
journal, January 1998
- Chow, Wong-Ho; Blot, William J.; Vaughan, Thomas L.
- JNCI: Journal of the National Cancer Institute, Vol. 90, Issue 2
Smoking and alcohol drinking in relation to the risk of esophageal squamous cell carcinoma: A population-based case-control study in China
journal, December 2017
- Yang, Xiaorong; Chen, Xingdong; Zhuang, Maoqiang
- Scientific Reports, Vol. 7, Issue 1
Global incidence of oesophageal cancer by histological subtype in 2012
journal, October 2014
- Arnold, Melina; Soerjomataram, Isabelle; Ferlay, Jacques
- Gut, Vol. 64, Issue 3
The association between change in body mass index and upper aerodigestive tract cancers in the ARCAGE project: Multicenter case-control study
journal, January 2011
- Park, Sungshim Lani; Lee, Yuan-Chin Amy; Marron, Manuela
- International Journal of Cancer, Vol. 128, Issue 6
Height and Body Mass Index in Relation to Esophageal Cancer; 23-year Follow-up of Two Million Norwegian Men and Women
journal, October 2004
- Engeland, Anders; Tretli, Steinar; Bjørge, Tone
- Cancer Causes & Control, Vol. 15, Issue 8
A prospective cohort study of obesity and risk of oesophageal and gastric adenocarcinoma in the NIH–AARP Diet and Health Study
journal, December 2011
- O'Doherty, Mark G.; Freedman, Neal D.; Hollenbeck, Albert R.
- Gut, Vol. 61, Issue 9
Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk
journal, August 2011
- Green, Jane; Cairns, Benjamin J.; Casabonne, Delphine
- The Lancet Oncology, Vol. 12, Issue 8
Very hot tea drinking increases esophageal squamous cell carcinoma risk in a high-risk area of China: a population-based case–control study
journal, January 2018
- Yang, Xiaorong; Ni, Yingchun; Yuan, Ziyu
- Clinical Epidemiology, Vol. Volume 10
Attained height, sex, and risk of cancer at different anatomic sites in the NIH-AARP Diet and Health Study
journal, October 2014
- Kabat, Geoffrey C.; Kim, Mimi Y.; Hollenbeck, Albert R.
- Cancer Causes & Control, Vol. 25, Issue 12
Body size and composition and the risk of gastric and oesophageal adenocarcinoma
journal, January 2006
- MacInnis, Robert J.; English, Dallas R.; Hopper, John L.
- International Journal of Cancer, Vol. 118, Issue 10
Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis
journal, January 2013
- Flegal, Katherine M.; Kit, Brian K.; Orpana, Heather
- JAMA, Vol. 309, Issue 1
Using SITAR (SuperImposition by Translation and Rotation) to estimate age at peak height velocity in Avon Longitudinal Study of Parents and Children
journal, January 2018
- Frysz, Monika; Howe, Laura D.; Tobias, Jonathan H.
- Wellcome Open Research, Vol. 3
Pooled cohort study on height and risk of cancer and cancer death
journal, October 2013
- Wirén, Sara; Häggström, Christel; Ulmer, Hanno
- Cancer Causes & Control, Vol. 25, Issue 2
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
journal, September 2018
- Bray, Freddie; Ferlay, Jacques; Soerjomataram, Isabelle
- CA: A Cancer Journal for Clinicians, Vol. 68, Issue 6
Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments
journal, October 2018
- O’Sullivan, Jacintha; Lysaght, Joanne; Donohoe, Claire L.
- Nature Reviews Gastroenterology & Hepatology, Vol. 15, Issue 11
Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study
journal, November 2007
- Reeves, Gillian K.; Pirie, Kirstin; Beral, Valerie
- BMJ, Vol. 335, Issue 7630
Large body size and sedentary lifestyle during childhood and early adulthood and esophageal squamous cell carcinoma in a high-risk population
journal, November 2011
- Etemadi, A.; Golozar, A.; Kamangar, F.
- Annals of Oncology, Vol. 23, Issue 6
Somatic mutant clones colonize the human esophagus with age
journal, October 2018
- Martincorena, Iñigo; Fowler, Joanna C.; Wabik, Agnieszka
- Science, Vol. 362, Issue 6417
Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus
journal, October 2007
- Whiteman, D. C.; Sadeghi, S.; Pandeya, N.
- Gut, Vol. 57, Issue 2
Body mass index, long-term weight change, and esophageal squamous cell carcinoma: Is the inverse association modified by smoking status?
journal, August 2011
- Lahmann, Petra H.; Pandeya, Nirmala; Webb, Penelope M.
- Cancer, Vol. 118, Issue 7
Obesity paradox in cancer: new insights provided by body composition
journal, February 2014
- Gonzalez, Maria Cristina; Pastore, Carla A.; Orlandi, Silvana P.
- The American Journal of Clinical Nutrition, Vol. 99, Issue 5
Anthropometry and Esophageal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition
journal, June 2009
- Steffen, A.; Schulze, M. B.; Pischon, T.
- Cancer Epidemiology Biomarkers & Prevention, Vol. 18, Issue 7
Poor oral health is associated with an increased risk of esophageal squamous cell carcinoma - a population-based case-control study in China: Oral health and risk of esophageal squamous cell carcinoma
journal, November 2016
- Chen, Xingdong; Yuan, Ziyu; Lu, Ming
- International Journal of Cancer, Vol. 140, Issue 3
Esophageal cancer and body mass index: Results from a prospective study of 220,000 men in China and a meta-analysis of published studies
journal, December 2007
- Smith, Margaret; Zhou, Maigeng; Whitlock, Gary
- International Journal of Cancer, Vol. 122, Issue 7
Esophageal cancer: epidemiology, pathogenesis and prevention
journal, August 2008
- Umar, Sarah B.; Fleischer, David E.
- Nature Clinical Practice Gastroenterology & Hepatology, Vol. 5, Issue 9
Epidemiological features of esophageal cancer. Squamous cell carcinoma versus adenocarcinoma
journal, June 2014
- Henry, Maria Aparecida Coelho de Arruda; Lerco, Mauro Masson; Ribeiro, Priscila Watson
- Acta Cirurgica Brasileira, Vol. 29, Issue 6
Dietary habits and esophageal cancer: Dietary habits and esophageal cancer
journal, June 2013
- Palladino-Davis, A. G.; Mendez, B. M.; Fisichella, P. M.
- Diseases of the Esophagus, Vol. 28, Issue 1
Are Cell Number and Cell Proliferation Risk Factors for Cancer?1
journal, July 1988
- Albanes, D.; Winick, M.
- JNCI Journal of the National Cancer Institute, Vol. 80, Issue 10
Risk of Esophageal Adenocarcinoma Decreases With Height, Based on Consortium Analysis and Confirmed by Mendelian Randomization
journal, October 2014
- Thrift, Aaron P.; Risch, Harvey A.; Onstad, Lynn
- Clinical Gastroenterology and Hepatology, Vol. 12, Issue 10
Body mass index in relation to oesophageal and oesophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON Consortium
journal, November 2012
- Hoyo, Cathrine; Cook, Michael B.; Kamangar, Farin
- International Journal of Epidemiology, Vol. 41, Issue 6
Gastroesophageal Reflux Does Not Alter Effects of Body Mass Index on Risk of Esophageal Adenocarcinoma
journal, January 2014
- Lagergren, Jesper; Mattsson, Fredrik; Nyrén, Olof
- Clinical Gastroenterology and Hepatology, Vol. 12, Issue 1
Body mass index and long-term risk of death from esophageal squamous cell carcinoma in a Chinese population: BMI and ESCC risk in Chinese
journal, April 2016
- Wang, Shao-Ming; Fan, Jin-Hu; Jia, Meng-Meng
- Thoracic Cancer, Vol. 7, Issue 4
The Figure Rating Scale as an Index of Weight Status of Women on Videotape*
journal, December 2006
- Cardinal, Tiffany M.; Kaciroti, Niko; Lumeng, Julie C.
- Obesity, Vol. 14, Issue 12
Body mass index, height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study
journal, June 2007
- Merry, A. H. H.; Schouten, L. J.; Goldbohm, R. A.
- Gut, Vol. 56, Issue 11