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Title: Laser‐Induced Nanodroplet Injection and Reconfigurable Double Emulsions with Designed Inner Structures

Abstract

Microfabrication of complex double emulsion droplets with controlled substructures, which resemble biological cells, is an important but a highly challenging subject. Here, a new approach is proposed based on laser-induced injection of water nanodroplets into a liquid crystal (LC) drop. In contrast to the conventional top-down microfluidic fabrication, this method employs a series of bottom-up strategies such as nanodroplet injection, spontaneous and assisted coalescence, elastically driven actuation, and self-assembly. Each step is controlled precisely by adjusting the laser beam, interfacial tension, and its gradients, surface anchoring, and elasticity of the LC. Whispering gallery mode illumination is used to monitor the injection of droplets. A broad spectrum of double emulsions with a predesigned hierarchical architecture is fabricated and reconfigured by temperature, laser-induced coalescence, and injection. The proposed bottom-up method to produce customized microemulsions that are responsive to environmental cues can be used in the development of drug delivery systems, biosensors, and functional soft matter microstructures.

Authors:
 [1];  [1];  [2];  [3];  [4]; ORCiD logo [1]
+ Show Author Affiliations
  1. Department of Electrical and Computer EngineeringSungkyunkwan University Suwon 16419 Republic of Korea
  2. Department of Electrical and Computer EngineeringSungkyunkwan University Suwon 16419 Republic of Korea, Merck Performance Materials Ltd. Pyeongtaek 17956 Republic of Korea
  3. Advanced Materials and Liquid Crystal InstituteKent State University Kent OH 44242 USA
  4. Advanced Materials and Liquid Crystal InstituteKent State University Kent OH 44242 USA, Department of PhysicsKent State University Kent OH 44242 USA
Publication Date:
Research Org.:
Kent State Univ., Kent, OH (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Research Foundation of Korea (NRF); Ministry of Science and ICT; China Scholarship Council
OSTI Identifier:
1560273
Alternate Identifier(s):
OSTI ID: 1560274; OSTI ID: 1623473
Grant/Contract Number:  
SC0019105; NRF‐2019R1A2C2008359
Resource Type:
Published Article
Journal Name:
Advanced Science
Additional Journal Information:
Journal Name: Advanced Science Journal Volume: 6 Journal Issue: 17; Journal ID: ISSN 2198-3844
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
Germany
Language:
English
Subject:
Chemistry; Science & Technology - Other Topics; Materials Science

Citation Formats

Guo, Jin‐Kun, Hong, Seung‐Ho, Yoon, Hyun‐Jin, Babakhanova, Greta, Lavrentovich, Oleg D., and Song, Jang‐Kun. Laser‐Induced Nanodroplet Injection and Reconfigurable Double Emulsions with Designed Inner Structures. Germany: N. p., 2019. Web. doi:10.1002/advs.201900785.
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Guo, Jin‐Kun, Hong, Seung‐Ho, Yoon, Hyun‐Jin, Babakhanova, Greta, Lavrentovich, Oleg D., & Song, Jang‐Kun. Laser‐Induced Nanodroplet Injection and Reconfigurable Double Emulsions with Designed Inner Structures. Germany. doi:10.1002/advs.201900785.
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Guo, Jin‐Kun, Hong, Seung‐Ho, Yoon, Hyun‐Jin, Babakhanova, Greta, Lavrentovich, Oleg D., and Song, Jang‐Kun. Wed . "Laser‐Induced Nanodroplet Injection and Reconfigurable Double Emulsions with Designed Inner Structures". Germany. doi:10.1002/advs.201900785.
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@article{osti_1560273,
title = {Laser‐Induced Nanodroplet Injection and Reconfigurable Double Emulsions with Designed Inner Structures},
author = {Guo, Jin‐Kun and Hong, Seung‐Ho and Yoon, Hyun‐Jin and Babakhanova, Greta and Lavrentovich, Oleg D. and Song, Jang‐Kun},
abstractNote = {Microfabrication of complex double emulsion droplets with controlled substructures, which resemble biological cells, is an important but a highly challenging subject. Here, a new approach is proposed based on laser-induced injection of water nanodroplets into a liquid crystal (LC) drop. In contrast to the conventional top-down microfluidic fabrication, this method employs a series of bottom-up strategies such as nanodroplet injection, spontaneous and assisted coalescence, elastically driven actuation, and self-assembly. Each step is controlled precisely by adjusting the laser beam, interfacial tension, and its gradients, surface anchoring, and elasticity of the LC. Whispering gallery mode illumination is used to monitor the injection of droplets. A broad spectrum of double emulsions with a predesigned hierarchical architecture is fabricated and reconfigured by temperature, laser-induced coalescence, and injection. The proposed bottom-up method to produce customized microemulsions that are responsive to environmental cues can be used in the development of drug delivery systems, biosensors, and functional soft matter microstructures.},
doi = {10.1002/advs.201900785},
journal = {Advanced Science},
number = 17,
volume = 6,
place = {Germany},
year = {2019},
month = {7}
}
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DOI: 10.1002/advs.201900785
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