Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling

Bian, Xuting; Liu, Tianyao; Zhou, Mei; He, Gang; Ma, Yuanyuan; Shi, Youxing; Wang, Yunjiao; Tang, Hong; Kang, Xia; Yang, Mingyu; Gustafsson, Jan‐Åke; Fan, Xiaotang; Tang, Kanglai

doi:10.1111/jcmm.14604

Title: Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling

Authors:

^[1]; Liu, Tianyao ^[2]; Zhou, Mei ^[1]; He, Gang ^[1]; Ma, Yuanyuan ^[2]; Shi, Youxing ^[1];

^[1]; Tang, Hong ^[1]; Kang, Xia ^[1]; Yang, Mingyu ^[1]; Gustafsson, Jan‐Åke ^[3]; Fan, Xiaotang ^[2]; Tang, Kanglai ^[1]

Department of Orthopedic Surgery Southwest Hospital, Army Medical University Chongqing China
Department of Developmental Neuropsychology, School of Psychology Third Military Medical University, Army Medical University Chongqing China
Center for Nuclear Receptors and Cell Signaling University of Houston Houston TX, Department of Biosciences and Nutrition, Center for Innovative Medicine Karolinska Institute Novum Sweden

Publication Date:: 2019-09-02

Sponsoring Org.:: USDOE

OSTI Identifier:: 1560237

Alternate Identifier(s):: OSTI ID: 1560238

Resource Type:: Published Article

Journal Name:: Journal of Cellular and Molecular Medicine

Additional Journal Information:: Journal Name: Journal of Cellular and Molecular Medicine Journal Volume: 23 Journal Issue: 11; Journal ID: ISSN 1582-1838

Publisher:: Wiley-Blackwell

Country of Publication:: Country unknown/Code not available

Language:: English

Citation Formats


                    Bian, Xuting, Liu, Tianyao, Zhou, Mei, He, Gang, Ma, Yuanyuan, Shi, Youxing, Wang, Yunjiao, Tang, Hong, Kang, Xia, Yang, Mingyu, Gustafsson, Jan‐Åke, Fan, Xiaotang, and Tang, Kanglai. Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling.  Country unknown/Code not available: N. p., 2019. 
Web.  doi:10.1111/jcmm.14604.

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                    Bian, Xuting, Liu, Tianyao, Zhou, Mei, He, Gang, Ma, Yuanyuan, Shi, Youxing, Wang, Yunjiao, Tang, Hong, Kang, Xia, Yang, Mingyu, Gustafsson, Jan‐Åke, Fan, Xiaotang, & Tang, Kanglai. Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling.  Country unknown/Code not available.  https://doi.org/10.1111/jcmm.14604

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                    Bian, Xuting, Liu, Tianyao, Zhou, Mei, He, Gang, Ma, Yuanyuan, Shi, Youxing, Wang, Yunjiao, Tang, Hong, Kang, Xia, Yang, Mingyu, Gustafsson, Jan‐Åke, Fan, Xiaotang, and Tang, Kanglai. Mon .  
"Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling".  Country unknown/Code not available.  https://doi.org/10.1111/jcmm.14604.

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@article{osti_1560237,

  title        = {Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling},

  author       = {Bian, Xuting and Liu, Tianyao and Zhou, Mei and He, Gang and Ma, Yuanyuan and Shi, Youxing and Wang, Yunjiao and Tang, Hong and Kang, Xia and Yang, Mingyu and Gustafsson, Jan‐Åke and Fan, Xiaotang and Tang, Kanglai},

  abstractNote = {},

  doi          = {10.1111/jcmm.14604},

  journal      = {Journal of Cellular and Molecular Medicine},

  number       = 11,

  volume       = 23,

  place        = {Country unknown/Code not available},

  year         = {2019},

  month        = {9}

}

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Title: Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up‐regulation of PPARγ signalling

Citation Formats

Estrogen Signaling through Estrogen Receptor Beta and G-Protein-Coupled Estrogen Receptor 1 in Human Cerebral Vascular Endothelial Cells: Implications for Cerebral Aneurysms journal, January 2013

Biologics for tendon repair journal, April 2015

Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis journal, January 2014

Corin protects H2O2-induced apoptosis through PI3K/AKT and NF-κB pathway in cardiomyocytes journal, January 2018

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An ERβ agonist induces browning of subcutaneous abdominal fat pad in obese female mice journal, December 2016

Inhibition of 5-LOX, COX-1, and COX-2 Increases Tendon Healing and Reduces Muscle Fibrosis and Lipid Accumulation After Rotator Cuff Repair journal, September 2014

In vitro tenocyte metabolism in aging and oestrogen deficiency journal, December 2012

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Achilles Tendon Rupture: A Review of Etiology, Population, Anatomy, Risk Factors, and Injury Prevention journal, December 2009

Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring journal, September 2007

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Achilles Tendon Disorders journal, October 1994

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Tendon injuries: Basic science and new repair proposals journal, July 2017

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Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewal journal, October 2012

Influence of acid and bile acid on ERK activity, PPARγ expression and cell proliferation in normal human esophageal epithelial cells journal, January 2006

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The effect of estrogen on tendon and ligament metabolism and function journal, September 2017

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Estrogen Signaling through Estrogen Receptor Beta and G-Protein-Coupled Estrogen Receptor 1 in Human Cerebral Vascular Endothelial Cells: Implications for Cerebral Aneurysms
journal, January 2013

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journal, April 2015

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journal, January 2014

Corin protects H2O2-induced apoptosis through PI3K/AKT and NF-κB pathway in cardiomyocytes
journal, January 2018

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journal, March 2015

An ERβ agonist induces browning of subcutaneous abdominal fat pad in obese female mice
journal, December 2016

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journal, September 2014

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journal, December 2012

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma
journal, October 2013

Achilles Tendon Rupture: A Review of Etiology, Population, Anatomy, Risk Factors, and Injury Prevention
journal, December 2009

Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring
journal, September 2007

Generation and reproductive phenotypes of mice lacking estrogen receptor
journal, December 1998

Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ
journal, June 2008

Achilles Tendon Disorders
journal, October 1994

Changes in transcription profile and cytoskeleton morphology in pelvic ligament fibroblasts in response to stretch: the effects of estradiol and levormeloxifene
journal, November 2007

Tendon injuries: Basic science and new repair proposals
journal, July 2017

In Vivo Identity of Tendon Stem Cells and the Roles of Stem Cells in Tendon Healing
journal, December 2013

Cell and Biologic-Based Treatment of Flexor Tendon Injuries
journal, September 2016

Di-(2-ethylhexyl)-phthalate induces apoptosis via the PPARγ/PTEN/AKT pathway in differentiated human embryonic stem cells
journal, September 2019

Comparison of Potentials of Stem Cells Isolated from Tendon and Bone Marrow for Musculoskeletal Tissue Engineering
journal, April 2012

The Effect of the Menstrual Cycle on Anterior Cruciate Ligament Injuries in Women as Determined by Hormone Levels
journal, March 2002

The Pleiotropic Effects of PPARs on Vascular Cells and Angiogenesis: Implications for Tissue Engineering
journal, March 2016

LXR agonist rescued the deficit in the proliferation of the cerebellar granule cells induced by dexamethasone
journal, September 2016

The Role of the Paratenon in Achilles Tendon Healing: A Study in Rats
journal, March 2018

Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewal
journal, October 2012

Influence of acid and bile acid on ERK activity, PPARγ expression and cell proliferation in normal human esophageal epithelial cells
journal, January 2006

Achilles tendon disorders
journal, March 2013

Biologics in Achilles tendon healing and repair: a review
journal, February 2015

The spatio-temporal dynamics of ligament healing
journal, March 2009

Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes
journal, May 2015

The effect of estrogen on tendon and ligament metabolism and function
journal, September 2017

PPAR Gamma and Angiogenesis: Endothelial Cells Perspective
journal, January 2016

The role of estrogen receptors in the control of energy and glucose homeostasis
journal, October 2008

17β-Estradiol inhibition of PPARγ-induced adipogenesis and adipocyte-specific gene expression
journal, February 2011

Biomechanical and histological comparison of the influence of oestrogen deficient state on tendon healing potential in rats
journal, April 2009

Effect of diosgenin on metabolic dysfunction: Role of ERβ in the regulation of PPARγ
journal, December 2015

Acute Achilles tendon rupture
journal, October 2015

The cross-talk between estrogen receptor and peroxisome proliferator-activated receptor gamma in thyroid cancer: ERs and PPAR Gamma in Thyroid Cancer
journal, October 2013

Identity of tendon stem cells - how much do we know?
journal, December 2012

Dexamethasone inhibits the differentiation of rat tendon stem cells into tenocytes by targeting the scleraxis gene
journal, August 2015

Characterization of differential properties of rabbit tendon stem cells and tenocytes
journal, January 2010

Achilles tendon healing: Long-term biomechanical effects of postoperative mobilization and immobilization in a new mouse model
journal, September 2002

Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing
journal, October 2017

Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche
journal, September 2007

Changes in extracellular matrix proteins in the cardinal ligaments of post-menopausal women with or without prolapse: a computerized immunohistomorphometric analysis
journal, October 2003