Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome function
Abstract
Gut microbiota dysbiosis is a recognized contributing factor to many noncommunicable diseases, but more evidence is still needed to illustrate its causative impact on mental and brain health disorders and mechanism(s) for targeted mitigation.
- Authors:
-
[1];
[1]
- College of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China
- Infinitus (China) Company Ltd Research & Development Center, Guangzhou 510640, China
- Department of Food Science and Technology, The Ohio State University, Columbus, USA, Department of Microbiology
- Publication Date:
- Sponsoring Org.:
- USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research
- OSTI Identifier:
- 1559347
- Grant/Contract Number:
- D9163940
- Resource Type:
- Publisher's Accepted Manuscript
- Journal Name:
- Food & Function
- Additional Journal Information:
- Journal Name: Food & Function Journal Volume: 10 Journal Issue: 9; Journal ID: ISSN 2042-6496
- Publisher:
- Royal Society of Chemistry (RSC)
- Country of Publication:
- United Kingdom
- Language:
- English
Citation Formats
Qu, Wan, Liu, Shuo, Zhang, Weijie, Zhu, Huawei, Tao, Qian, Wang, Hua, and Yan, He. Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome function. United Kingdom: N. p., 2019.
Web. doi:10.1039/C9FO00399A.
Qu, Wan, Liu, Shuo, Zhang, Weijie, Zhu, Huawei, Tao, Qian, Wang, Hua, & Yan, He. Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome function. United Kingdom. https://doi.org/10.1039/C9FO00399A
Qu, Wan, Liu, Shuo, Zhang, Weijie, Zhu, Huawei, Tao, Qian, Wang, Hua, and Yan, He. Wed .
"Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome function". United Kingdom. https://doi.org/10.1039/C9FO00399A.
@article{osti_1559347,
title = {Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome function},
author = {Qu, Wan and Liu, Shuo and Zhang, Weijie and Zhu, Huawei and Tao, Qian and Wang, Hua and Yan, He},
abstractNote = {Gut microbiota dysbiosis is a recognized contributing factor to many noncommunicable diseases, but more evidence is still needed to illustrate its causative impact on mental and brain health disorders and mechanism(s) for targeted mitigation.},
doi = {10.1039/C9FO00399A},
journal = {Food & Function},
number = 9,
volume = 10,
place = {United Kingdom},
year = {2019},
month = {9}
}
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https://doi.org/10.1039/C9FO00399A
https://doi.org/10.1039/C9FO00399A
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Works referenced in this record:
The Central Nervous System and the Gut Microbiome
journal, November 2016
- Sharon, Gil; Sampson, Timothy R.; Geschwind, Daniel H.
- Cell, Vol. 167, Issue 4
Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model
journal, December 2017
- Yang, Chun; Qu, Youge; Fujita, Yuko
- Translational Psychiatry, Vol. 7, Issue 12
Microbiota and host determinants of behavioural phenotype in maternally separated mice
journal, July 2015
- De Palma, G.; Blennerhassett, P.; Lu, J.
- Nature Communications, Vol. 6, Issue 1
The effect of Chaihu-Shugan-San and its components on the expression of ERK5 in the hippocampus of depressed rats
journal, March 2014
- Qiu, Juan; Hu, Sui-Yu; Zhang, Chun-Hu
- Journal of Ethnopharmacology, Vol. 152, Issue 2
Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex
journal, January 2017
- Moussaoui, Nabila; Jacobs, Jonathan P.; Larauche, Muriel
- Journal of Neurogastroenterology and Motility, Vol. 23, Issue 1
Impact of gut microbiota on neurological diseases: Diet composition and novel treatments
journal, July 2018
- Larroya-García, Ana; Navas-Carrillo, Diana; Orenes-Piñero, Esteban
- Critical Reviews in Food Science and Nutrition, Vol. 59, Issue 19
Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys
journal, September 1999
- Bailey, Michael T.; Coe, Christopher L.
- Developmental Psychobiology, Vol. 35, Issue 2
Reduced microbiome alpha diversity in young patients with ADHD
journal, July 2018
- Prehn-Kristensen, Alexander; Zimmermann, Alexandra; Tittmann, Lukas
- PLOS ONE, Vol. 13, Issue 7
New evidences on the altered gut microbiota in autism spectrum disorders
journal, February 2017
- Strati, Francesco; Cavalieri, Duccio; Albanese, Davide
- Microbiome, Vol. 5, Issue 1
Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies
journal, July 2019
- Pham, Thu Ha; Gardier, Alain M.
- Pharmacology & Therapeutics, Vol. 199
Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats
journal, May 2014
- Liu, Dexiang; Xie, Kai; Yang, Xudong
- Behavioural Brain Research, Vol. 264
Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences
journal, November 2010
- Kumar, Baldeep; Kuhad, Anurag; Chopra, Kanwaljit
- Psychopharmacology, Vol. 214, Issue 4
Major Depressive Disorder
journal, January 2008
- Belmaker, R. H.; Agam, Galila
- New England Journal of Medicine, Vol. 358, Issue 1
In vivo administration of valproate reduces the nerve terminal (synaptosomal) activity of GABA aminotransferase in discrete brain areas of rats
journal, October 1993
- Löscher, Wolfgang
- Neuroscience Letters, Vol. 160, Issue 2
Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome
journal, May 2017
- Labus, Jennifer S.; Hollister, Emily B.; Jacobs, Jonathan
- Microbiome, Vol. 5, Issue 1
In vitro fermentation of B-GOS: impact on faecal bacterial populations and metabolic activity in autistic and non-autistic children
journal, November 2016
- Grimaldi, Roberta; Cela, Drinalda; Swann, Jonathan R.
- FEMS Microbiology Ecology, Vol. 93, Issue 2
5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease
journal, December 2018
- Klein, Christian; Roussel, Guy; Brun, Susana
- Acta Neuropathologica Communications, Vol. 6, Issue 1
Gut Microbial Diversity Is Reduced in Smokers with Crohnʼs Disease
journal, January 2016
- Opstelten, Jorrit L.; Plassais, Jonathan; van Mil, Saskia W. C.
- Inflammatory Bowel Diseases, Vol. 22, Issue 9
Role of the Brain-Gut Axis in the Pathophysiology of Crohn’s Disease
journal, January 2008
- Stasi, Cristina; Orlandelli, Ermes
- Digestive Diseases, Vol. 26, Issue 2
Pathogenic potential of lactobacilli
journal, December 1994
- Harty, D. W. S.; Oakey, H. J.; Patrikakis, M.
- International Journal of Food Microbiology, Vol. 24, Issue 1-2
Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress
journal, April 2017
- Liu, Ya-Min; Shen, Ji-Duo; Xu, Li-Ping
- International Immunopharmacology, Vol. 45
Resources and Biological Activities of Natural Polyphenols
journal, December 2014
- Li, An-Na; Li, Sha; Zhang, Yu-Jie
- Nutrients, Vol. 6, Issue 12
Pathogenic relevance of Lactobacillus: a retrospective review of over 200 cases
journal, December 2004
- Cannon, J. P.; Lee, T. A.; Bolanos, J. T.
- European Journal of Clinical Microbiology & Infectious Diseases, Vol. 24, Issue 1
Altered gut microbiota in Rett syndrome
journal, July 2016
- Strati, Francesco; Cavalieri, Duccio; Albanese, Davide
- Microbiome, Vol. 4, Issue 1
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
journal, August 2011
- Bravo, J. A.; Forsythe, P.; Chew, M. V.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 38
Gut Microbiota is Altered in Patients with Alzheimer’s Disease
journal, May 2018
- Zhuang, Zhen-Qian; Shen, Lin-Lin; Li, Wei-Wei
- Journal of Alzheimer's Disease, Vol. 63, Issue 4
The burden of mental, neurological, and substance use disorders in China and India: a systematic analysis of community representative epidemiological studies
journal, July 2016
- Charlson, Fiona J.; Baxter, Amanda J.; Cheng, Hui G.
- The Lancet, Vol. 388, Issue 10042
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat
journal, November 2016
- Kelly, John R.; Borre, Yuliya; O' Brien, Ciaran
- Journal of Psychiatric Research, Vol. 82
Exercise-induced stress behavior, gut-microbiota-brain axis and diet: a systematic review for athletes
journal, November 2016
- Clark, Allison; Mach, Núria
- Journal of the International Society of Sports Nutrition, Vol. 13, Issue 1
Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies
journal, January 2007
- Ruhé, H. G.; Mason, N. S.; Schene, A. H.
- Molecular Psychiatry, Vol. 12, Issue 4
Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels
journal, August 2018
- Sales, Amanda J.; Crestani, Carlos C.; Guimarães, Francisco S.
- Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 86
Lactobacillus plantarum attenuates anxiety-related behavior and protects against stress-induced dysbiosis in adult zebrafish
journal, September 2016
- Davis, Daniel J.; Doerr, Holly M.; Grzelak, Agata K.
- Scientific Reports, Vol. 6, Issue 1
Plasma Metabonomics as a Novel Diagnostic Approach for Major Depressive Disorder
journal, January 2012
- Zheng, Peng; Gao, Hong C.; Li, Qi
- Journal of Proteome Research, Vol. 11, Issue 3
Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
journal, December 2013
- Hsiao, Elaine Y.; McBride, Sara W.; Hsien, Sophia
- Cell, Vol. 155, Issue 7
Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depression
journal, February 2015
- Chen, Guanghui; Yang, Deyu; Yang, Yongtao
- Behavioural Brain Research, Vol. 278
Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics
journal, May 2017
- Yu, Meng; Jia, Hongmei; Zhou, Chao
- Journal of Pharmaceutical and Biomedical Analysis, Vol. 138
Bifidobacterium in the gut microbiota confer resilience to chronic social defeat stress in mice
journal, April 2017
- Yang, Chun; Fujita, Yuko; Ren, Qian
- Scientific Reports, Vol. 7, Issue 1
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
journal, May 1997
- Murray, Christopher JL; Lopez, Alan D.
- The Lancet, Vol. 349, Issue 9063
Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota: INTERPLAY BETWEEN HERBAL MEDICINES AND GUT MICROBIOTA
journal, January 2017
- Xu, Jun; Chen, Hu-Biao; Li, Song-Lin
- Medicinal Research Reviews, Vol. 37, Issue 5
Dietary modulation of clostridial cluster XIVa gut bacteria (Roseburia spp.) by chitin–glucan fiber improves host metabolic alterations induced by high-fat diet in mice
journal, January 2012
- Neyrinck, Audrey M.; Possemiers, Sam; Verstraete, Willy
- The Journal of Nutritional Biochemistry, Vol. 23, Issue 1
Modulation of Gut Microbiome Composition and Function in Experimental Colitis Treated with Sulfasalazine
journal, September 2017
- Zheng, Haihui; Chen, Mingyi; Li, Yuan
- Frontiers in Microbiology, Vol. 8
Ruminococcus gnavus: An unusual pathogen in septic arthritis
journal, December 2014
- Titécat, Marie; Wallet, Frédéric; Vieillard, Marie-Hélène
- Anaerobe, Vol. 30
Safety assessment of probiotics for human use
journal, May 2010
- Sanders, Mary Ellen; Akkermans, Louis M. A.; Haller, Dirk
- Gut Microbes, Vol. 1, Issue 3
Metabolic factors-triggered inflammatory response drives antidepressant effects of exercise in CUMS rats
journal, August 2015
- Liu, Weina; Wang, Hongmei; Wang, Yangkai
- Psychiatry Research, Vol. 228, Issue 3
Gut Microbiota in Multiple Sclerosis: Possible Influence of Immunomodulators
journal, January 2015
- Cantarel, Brandi L.; Waubant, Emmanuelle; Chehoud, Christel
- Journal of Investigative Medicine, Vol. 63, Issue 5
A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota
journal, January 2017
- Zhao, Le; Zhang, Qi; Ma, Weini
- Food & Function, Vol. 8, Issue 12
A metagenome-wide association study of gut microbiota in type 2 diabetes
journal, September 2012
- Qin, Junjie; Li, Yingrui; Cai, Zhiming
- Nature, Vol. 490, Issue 7418
The Many Faces of Glutathione in Bacteria
journal, May 2006
- Masip, Lluis; Veeravalli, Karthik; Georgiou, George
- Antioxidants & Redox Signaling, Vol. 8, Issue 5-6
GABA and 5-HT systems are implicated in the anxiolytic-like effect of spinosin in mice
journal, January 2015
- Liu, Jie; Zhai, Wei-Min; Yang, Yuan-Xiao
- Pharmacology Biochemistry and Behavior, Vol. 128
Altered fecal microbiota composition in patients with major depressive disorder
journal, August 2015
- Jiang, Haiyin; Ling, Zongxin; Zhang, Yonghua
- Brain, Behavior, and Immunity, Vol. 48
Gut microbiota-involved mechanisms in enhancing systemic exposure of ginsenosides by coexisting polysaccharides in ginseng decoction
journal, March 2016
- Zhou, Shan-Shan; Xu, Jun; Zhu, He
- Scientific Reports, Vol. 6, Issue 1
A randomised controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial)
journal, January 2017
- Jacka, Felice N.; O’Neil, Adrienne; Opie, Rachelle
- BMC Medicine, Vol. 15, Issue 1
Tightening the Case for Gut Microbiota in Autism-Spectrum Disorder
journal, March 2017
- Braun, Jonathan
- Cellular and Molecular Gastroenterology and Hepatology, Vol. 3, Issue 2
Chronic treatment with baicalin prevents the chronic mild stress-induced depressive-like behavior: Involving the inhibition of cyclooxygenase-2 in rat brain
journal, January 2013
- Li, Yu-Cheng; Shen, Ji-Duo; Li, Jing
- Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 40
Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota
journal, June 2015
- Chang, Chih-Jung; Lin, Chuan-Sheng; Lu, Chia-Chen
- Nature Communications, Vol. 6, Issue 1
Inactivation of beef brain alpha-ketoglutarate dehydrogenase complex by valproic acid and valproic acid metabolites. Possible mechanism of anticonvulsant and toxic actions.
journal, November 1990
- Luder, A. S.; Parks, J. K.; Frerman, F.
- Journal of Clinical Investigation, Vol. 86, Issue 5
Gastrointestinal microbiota in children with autism in Slovakia
journal, January 2015
- Tomova, Aleksandra; Husarova, Veronika; Lakatosova, Silvia
- Physiology & Behavior, Vol. 138
Direction of the brain–gut pathway in functional gastrointestinal disorders
journal, March 2012
- Whitehouse, Heather J.; Ford, Alexander C.
- Gut, Vol. 61, Issue 9
Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula
journal, October 2014
- Xu, Jia; Lian, Fengmei; Zhao, Linhua
- The ISME Journal, Vol. 9, Issue 3
A metagenomics approach to the intestinal microbiome structure and function in high fat diet-induced obesity mice fed with oolong tea polyphenols
journal, January 2018
- Cheng, Mei; Zhang, Xin; Zhu, Jieyu
- Food & Function, Vol. 9, Issue 2
Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010
journal, November 2013
- Whiteford, Harvey A.; Degenhardt, Louisa; Rehm, Jürgen
- The Lancet, Vol. 382, Issue 9904
Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism
journal, April 2016
- Zheng, P.; Zeng, B.; Zhou, C.
- Molecular Psychiatry, Vol. 21, Issue 6
Prevotella and Klebsiella proportions in fecal microbial communities are potential characteristic parameters for patients with major depressive disorder
journal, January 2017
- Lin, Ping; Ding, Bingyu; Feng, Chunyan
- Journal of Affective Disorders, Vol. 207
Correlation between the human fecal microbiota and depression
journal, June 2014
- Naseribafrouei, A.; Hestad, K.; Avershina, E.
- Neurogastroenterology & Motility, Vol. 26, Issue 8