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Title: Biocuration: Distilling data into knowledge

Journal Article · · PLoS Biology (Online)

Data, including information generated from them by processing and analysis, are an asset with measurable value. The assets that biological research funding produces are the data generated, the information derived from these data, and, ultimately, the discoveries and knowledge these lead to. From the time when Henry Oldenburg published the first scientific journal in 1665 (Proceedings of the Royal Society) to the founding of the United States National Library of Medicine in 1879 to the present, there has been a sustained drive to improve how researchers can record and discover what is known. Researchers' experimental work builds upon years and (collectively) billions of dollars' worth of earlier work. Today, researchers are generating data at ever-faster rates because of advances in instrumentation and technology, coupled with decreases in production costs. Unfortunately, the ability of researchers to manage and disseminate their results has not kept pace, so their work cannot achieve its maximal impact. Strides have recently been made, but more awareness is needed of the essential role that biological data resources, including biocuration, play in maintaining and linking this ever-growing flood of data and information. The aim of this paper is to describe the nature of data as an asset, the role biocurators play in increasing its value, and consistent, practical means to measure effectiveness that can guide planning and justify costs in biological research information resources' development and management.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Contributing Organization:
International Society for Biocuration
Grant/Contract Number:
AC02-05CH11231
OSTI ID:
1559141
Journal Information:
PLoS Biology (Online), Journal Name: PLoS Biology (Online) Journal Issue: 4 Vol. 16; ISSN 1545-7885
Publisher:
Public Library of ScienceCopyright Statement
Country of Publication:
United States
Language:
English

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ProPheno 1.0: An Online Dataset for Accelerating the Complete Characterization of the Human Protein-Phenotype Landscape in Biomedical Literature conference February 2020
Ten quick tips for biocuration journal May 2019
Annotation of phenotypes using ontologies: a gold standard for the training and evaluation of natural language processing systems journal January 2018
A nomenclature and classification for the congenital myasthenic syndromes: preparing for FAIR data in the genomic era journal November 2018
COPO: a metadata platform for brokering FAIR data in the life sciences journal January 2020
Ten quick tips for biocuration journal May 2019