Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation

Yan, Jipeng; Liang, Ling; He, Qian; Li, Chenlin; Xu, Feng; Sun, Jian; Goh, Ee‐Been; Konda, N. V. S. N. Murthy; Beller, Harry R.; Simmons, Blake A.; Pray, Todd R.; Thompson, Vicki S.; Singh, Seema; Sun, Ning

doi:10.1002/cssc.201901084

Title: Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation

Abstract

Abstract The conversion of municipal solid waste (MSW) and lignocellulosic biomass blends to methyl ketones (MKs) was investigated by using bioderived ionic liquid (bionic liquid)‐based hydrolysates followed by fermentation with an engineered Escherichia coli strain. The hydrolysates were produced by a one‐pot process using six types of MSW–biomass blends, choline‐based bionic liquids, and commercial enzymes. Based on the sugar yields, one blend (corn stover/MSW=95:5, w / w ) and two bionic liquids {cholinium lysinate ([Ch][Lys]) and cholinium aspartate ([Ch] ₂ [Asp])} were selected for scale‐up studies. Maximum yields of 82.3 % glucose and 54.4 % xylose were obtained from the selected blend in the scale‐up studies (6 L), which was comparable with 83.6 % glucose and 52.8 % xylose obtained at a smaller scale (0.2 L). Comparable or higher yields of medium‐chain (C ₁₁ –C ₁₇ ) MKs were achieved by using the MSW–biomass blend‐derived hydrolysates, relative to the sugar controls (glucose and xylose) with similar sugar feeding concentrations. Up to 1145 mg L ⁻¹ of MKs was produced by using MSW–biomass‐derived hydrolysates, and the MK titer decreased to 300 mg L ⁻¹ when the bionic‐liquid concentration in the hydrolysate increased from 1 to 2 %, indicative of bionic‐liquid inhibition. Technoeconomic analysis was conducted to investigate the economic potential of usingmore »« less

Authors:

^[1]; Liang, Ling ^[1]; He, Qian ^[1]; Li, Chenlin ^[2]; Xu, Feng ^[3]; Sun, Jian ^[3]; Goh, Ee‐Been ^[4]; Konda, N. V. S. N. Murthy ^[4]; Beller, Harry R. ^[5]; Simmons, Blake A. ^[4]; Pray, Todd R. ^[1]; Thompson, Vicki S. ^[2]; Singh, Seema ^[3];

^[1]

Advanced Biofuels and Bioproducts Process Development Unit Lawrence Berkeley National Laboratory Emeryville CA USA, Biological Systems and Engineering Division Lawrence Berkeley National Laboratory Berkeley CA USA
Energy, and Environmental Science and Technology Idaho National Laboratory Idaho Falls ID USA
Joint BioEnergy Institute Lawrence Berkeley National Laboratory Berkeley CA USA, Biological and Materials Sciences Center Sandia National Laboratories Livermore CA USA
Biological Systems and Engineering Division Lawrence Berkeley National Laboratory Berkeley CA USA, Joint BioEnergy Institute Lawrence Berkeley National Laboratory Berkeley CA USA
Joint BioEnergy Institute Lawrence Berkeley National Laboratory Berkeley CA USA, Earth and Environmental Sciences Lawrence Berkeley National Laboratory Berkeley CA USA

Publication Date:: Fri Aug 23 00:00:00 EDT 2019

Sponsoring Org.:: USDOE

OSTI Identifier:: 1558672

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: ChemSusChem

Additional Journal Information:: Journal Name: ChemSusChem Journal Volume: 12 Journal Issue: 18; Journal ID: ISSN 1864-5631

Publisher:: Wiley Blackwell (John Wiley & Sons)

Country of Publication:: Germany

Language:: English

Citation Formats


                    Yan, Jipeng, Liang, Ling, He, Qian, Li, Chenlin, Xu, Feng, Sun, Jian, Goh, Ee‐Been, Konda, N. V. S. N. Murthy, Beller, Harry R., Simmons, Blake A., Pray, Todd R., Thompson, Vicki S., Singh, Seema, and Sun, Ning. Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation.  Germany: N. p., 2019. 
Web.  doi:10.1002/cssc.201901084.

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                    Yan, Jipeng, Liang, Ling, He, Qian, Li, Chenlin, Xu, Feng, Sun, Jian, Goh, Ee‐Been, Konda, N. V. S. N. Murthy, Beller, Harry R., Simmons, Blake A., Pray, Todd R., Thompson, Vicki S., Singh, Seema, & Sun, Ning. Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation.  Germany.  https://doi.org/10.1002/cssc.201901084

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                    Yan, Jipeng, Liang, Ling, He, Qian, Li, Chenlin, Xu, Feng, Sun, Jian, Goh, Ee‐Been, Konda, N. V. S. N. Murthy, Beller, Harry R., Simmons, Blake A., Pray, Todd R., Thompson, Vicki S., Singh, Seema, and Sun, Ning. Fri .  
"Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation".  Germany.  https://doi.org/10.1002/cssc.201901084.

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@article{osti_1558672,

  title        = {Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation},

  author       = {Yan, Jipeng and Liang, Ling and He, Qian and Li, Chenlin and Xu, Feng and Sun, Jian and Goh, Ee‐Been and Konda, N. V. S. N. Murthy and Beller, Harry R. and Simmons, Blake A. and Pray, Todd R. and Thompson, Vicki S. and Singh, Seema and Sun, Ning},

  abstractNote = {Abstract The conversion of municipal solid waste (MSW) and lignocellulosic biomass blends to methyl ketones (MKs) was investigated by using bioderived ionic liquid (bionic liquid)‐based hydrolysates followed by fermentation with an engineered Escherichia coli strain. The hydrolysates were produced by a one‐pot process using six types of MSW–biomass blends, choline‐based bionic liquids, and commercial enzymes. Based on the sugar yields, one blend (corn stover/MSW=95:5, w / w ) and two bionic liquids {cholinium lysinate ([Ch][Lys]) and cholinium aspartate ([Ch] 2 [Asp])} were selected for scale‐up studies. Maximum yields of 82.3 % glucose and 54.4 % xylose were obtained from the selected blend in the scale‐up studies (6 L), which was comparable with 83.6 % glucose and 52.8 % xylose obtained at a smaller scale (0.2 L). Comparable or higher yields of medium‐chain (C 11 –C 17 ) MKs were achieved by using the MSW–biomass blend‐derived hydrolysates, relative to the sugar controls (glucose and xylose) with similar sugar feeding concentrations. Up to 1145 mg L −1 of MKs was produced by using MSW–biomass‐derived hydrolysates, and the MK titer decreased to 300 mg L −1 when the bionic‐liquid concentration in the hydrolysate increased from 1 to 2 %, indicative of bionic‐liquid inhibition. Technoeconomic analysis was conducted to investigate the economic potential of using the selected MSW–biomass blend as a feedstock to produce MKs.},

  doi          = {10.1002/cssc.201901084},

  journal      = {ChemSusChem},

  number       = 18,

  volume       = 12,

  place        = {Germany},

  year         = {Fri Aug 23 00:00:00 EDT 2019},

  month        = {Fri Aug 23 00:00:00 EDT 2019}

}

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Title: Methyl Ketones from Municipal Solid Waste Blends by One‐Pot Ionic‐Liquid Pretreatment, Saccharification, and Fermentation

Abstract

Citation Formats

Evaluation of Toxicity and Biodegradability of Cholinium Amino Acids Ionic Liquids journal, March 2013

Blending municipal solid waste with corn stover for sugar production using ionic liquid process journal, June 2015

Modeling interactions between lignocellulose and ionic liquids using DFT-D journal, January 2011

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The effect of the ionic liquid anion in the pretreatment of pine wood chips journal, January 2010

Pretreatment of lignocellulosic biomass with renewable cholinium ionic liquids: Biomass fractionation, enzymatic digestion and ionic liquid reuse journal, September 2015

Dissolution of Wood in Ionic Liquids journal, October 2007

Substantial improvements in methyl ketone production in E. coli and insights on the pathway from in vitro studies journal, November 2014

Synthesis of methyl ketones by metabolically engineered Escherichia coli journal, August 2012

Current and Potential U.S. Corn Stover Supplies journal, January 2007

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Impact of high biomass loading on ionic liquid pretreatment journal, January 2013

CO 2 enabled process integration for the production of cellulosic ethanol using bionic liquids journal, January 2016

Lignin plays a negative role in the biochemical process for producing lignocellulosic biofuels journal, June 2014

Impact of Ionic Liquid Pretreatment Conditions on Cellulose Crystalline Structure Using 1-Ethyl-3-methylimidazolium Acetate journal, August 2012

Methods for recovery of ionic liquids—A review journal, May 2014

Scale-up and evaluation of high solid ionic liquid pretreatment and enzymatic hydrolysis of switchgrass journal, January 2013

Conversion of cellulose rich municipal solid waste blends using ionic liquids: feedstock convertibility and process scale-up journal, January 2017

Comparison of enzymatic reactivity of corn stover solids prepared by dilute acid, AFEX™, and ionic liquid pretreatments journal, January 2014

Fractionation of Lignocellulosic Materials with Ionic Liquids. 1. Effect of Mechanical Treatment journal, November 2011

Relevance of the acidic 1-butyl-3-methylimidazolium hydrogen sulphate ionic liquid in the selective catalysis of the biomass hemicellulose fraction journal, January 2015

Enhanced production of glucose and xylose with partial dissolution of corn stover in ionic liquid, 1-Ethyl-3-methylimidazolium acetate journal, June 2012

Glucose Solvation by the Ionic Liquid 1,3-Dimethylimidazolium Chloride: A Simulation Study journal, December 2007

Impact of mixed feedstocks and feedstock densification on ionic liquid pretreatment efficiency journal, January 2013

Novel renewable ionic liquids as highly effective solvents for pretreatment of rice straw biomass by selective removal of lignin journal, April 2012

Visualization of biomass solubilization and cellulose regeneration during ionic liquid pretreatment of switchgrass journal, September 2009

Impact of ionic liquid pretreated plant biomass on Saccharomyces cerevisiae growth and biofuel production journal, January 2011

Switchable Ionic liquids (SILs) based on glycerol and acid gases journal, January 2011

Switchable ionic liquids based on di-carboxylic acids for one-pot conversion of biomass to an advanced biofuel journal, January 2016

Engineering of Bacterial Methyl Ketone Synthesis for Biofuels journal, October 2011

Ionic liquids from renewable biomaterials: synthesis, characterization and application in the pretreatment of biomass journal, January 2012

Ionic Liquids: New Targets and Media for α-Amino Acid and Peptide Chemistry journal, December 2008

Pre-treatment of lignocellulosic biomass using ionic liquids: Wheat straw fractionation journal, August 2013

Comparing the Recalcitrance of Eucalyptus, Pine, and Switchgrass Using Ionic Liquid and Dilute Acid Pretreatments journal, May 2012

Fractionation of Lignocellulosic Materials Using Ionic Liquids: Part 2. Effect of Particle Size on the Mechanisms of Fractionation journal, February 2013

Rhodosporidium toruloides: a new platform organism for conversion of lignocellulose into terpene biofuels and bioproducts journal, October 2017

Factors Affecting Wood Dissolution and Regeneration of Ionic Liquids journal, March 2010

Acidolysis of Wood in Ionic Liquids journal, April 2010

Acidic Ionic Liquids as Sustainable Approach of Cellulose and Lignocellulosic Biomass Conversion without Additional Catalysts journal, February 2015

Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover report, March 2011

DEVELOPMENTAL NEUROSCIENCE:Enhanced: Choline, a Vital Amine journal, August 1998

DESIGNER SOLVENTS: Ionic liquids may boost clean technology development journal, March 1998

One-pot integrated biofuel production using low-cost biocompatible protic ionic liquids journal, January 2017

Significantly enhancing enzymatic hydrolysis of rice straw after pretreatment using renewable ionic liquid–water mixtures journal, May 2013

Loop vs. batch reactor setups in the fractionation of birch chips using switchable ionic liquids journal, February 2014

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids journal, March 2012

PHA Recovery from Biomass journal, August 2013

Scale-Up of Ionic Liquid-Based Fractionation of Single and Mixed Feedstocks journal, February 2015

One-pot ionic liquid pretreatment and saccharification of switchgrass journal, January 2013

Production of first and second generation biofuels: A comprehensive review journal, February 2010

Scale-up and process integration of sugar production by acidolysis of municipal solid waste/corn stover blends in ionic liquids journal, January 2017

Switchable Ionic Liquids as Delignification Solvents for Lignocellulosic Materials journal, March 2014

Evaluation of Toxicity and Biodegradability of Cholinium Amino Acids Ionic Liquids
journal, March 2013

Blending municipal solid waste with corn stover for sugar production using ionic liquid process
journal, June 2015

Modeling interactions between lignocellulose and ionic liquids using DFT-D
journal, January 2011

Transforming biomass conversion with ionic liquids: process intensification and the development of a high-gravity, one-pot process for the production of cellulosic ethanol
journal, January 2016

The mechanisms of carbon catabolite repression in bacteria
journal, April 2008

Sugars and sugar derivatives in ionic liquid media obtained from lignocellulosic biomass: Comparison of capillary electrophoresis and chromatographic analysis
journal, March 2014

The effect of the ionic liquid anion in the pretreatment of pine wood chips
journal, January 2010

Pretreatment of lignocellulosic biomass with renewable cholinium ionic liquids: Biomass fractionation, enzymatic digestion and ionic liquid reuse
journal, September 2015

Dissolution of Wood in Ionic Liquids
journal, October 2007

Substantial improvements in methyl ketone production in E. coli and insights on the pathway from in vitro studies
journal, November 2014

Synthesis of methyl ketones by metabolically engineered Escherichia coli
journal, August 2012

Current and Potential U.S. Corn Stover Supplies
journal, January 2007

Comparison of dilute acid and ionic liquid pretreatment of switchgrass: Biomass recalcitrance, delignification and enzymatic saccharification
journal, July 2010

Impact of high biomass loading on ionic liquid pretreatment
journal, January 2013

CO ₂ enabled process integration for the production of cellulosic ethanol using bionic liquids
journal, January 2016

Lignin plays a negative role in the biochemical process for producing lignocellulosic biofuels
journal, June 2014

Impact of Ionic Liquid Pretreatment Conditions on Cellulose Crystalline Structure Using 1-Ethyl-3-methylimidazolium Acetate
journal, August 2012

Methods for recovery of ionic liquids—A review
journal, May 2014

Scale-up and evaluation of high solid ionic liquid pretreatment and enzymatic hydrolysis of switchgrass
journal, January 2013

Conversion of cellulose rich municipal solid waste blends using ionic liquids: feedstock convertibility and process scale-up
journal, January 2017

Comparison of enzymatic reactivity of corn stover solids prepared by dilute acid, AFEX™, and ionic liquid pretreatments
journal, January 2014

Fractionation of Lignocellulosic Materials with Ionic Liquids. 1. Effect of Mechanical Treatment
journal, November 2011

Relevance of the acidic 1-butyl-3-methylimidazolium hydrogen sulphate ionic liquid in the selective catalysis of the biomass hemicellulose fraction
journal, January 2015

Enhanced production of glucose and xylose with partial dissolution of corn stover in ionic liquid, 1-Ethyl-3-methylimidazolium acetate
journal, June 2012

Glucose Solvation by the Ionic Liquid 1,3-Dimethylimidazolium Chloride: A Simulation Study
journal, December 2007

Impact of mixed feedstocks and feedstock densification on ionic liquid pretreatment efficiency
journal, January 2013

Novel renewable ionic liquids as highly effective solvents for pretreatment of rice straw biomass by selective removal of lignin
journal, April 2012

Visualization of biomass solubilization and cellulose regeneration during ionic liquid pretreatment of switchgrass
journal, September 2009

Impact of ionic liquid pretreated plant biomass on Saccharomyces cerevisiae growth and biofuel production
journal, January 2011

Switchable Ionic liquids (SILs) based on glycerol and acid gases
journal, January 2011

Switchable ionic liquids based on di-carboxylic acids for one-pot conversion of biomass to an advanced biofuel
journal, January 2016

Engineering of Bacterial Methyl Ketone Synthesis for Biofuels
journal, October 2011

Ionic liquids from renewable biomaterials: synthesis, characterization and application in the pretreatment of biomass
journal, January 2012

Ionic Liquids: New Targets and Media for α-Amino Acid and Peptide Chemistry
journal, December 2008

Pre-treatment of lignocellulosic biomass using ionic liquids: Wheat straw fractionation
journal, August 2013

Comparing the Recalcitrance of Eucalyptus, Pine, and Switchgrass Using Ionic Liquid and Dilute Acid Pretreatments
journal, May 2012

Fractionation of Lignocellulosic Materials Using Ionic Liquids: Part 2. Effect of Particle Size on the Mechanisms of Fractionation
journal, February 2013

Rhodosporidium toruloides: a new platform organism for conversion of lignocellulose into terpene biofuels and bioproducts
journal, October 2017

Factors Affecting Wood Dissolution and Regeneration of Ionic Liquids
journal, March 2010

Acidolysis of Wood in Ionic Liquids
journal, April 2010

Acidic Ionic Liquids as Sustainable Approach of Cellulose and Lignocellulosic Biomass Conversion without Additional Catalysts
journal, February 2015

Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover
report, March 2011

DEVELOPMENTAL NEUROSCIENCE:Enhanced: Choline, a Vital Amine
journal, August 1998

DESIGNER SOLVENTS: Ionic liquids may boost clean technology development
journal, March 1998

One-pot integrated biofuel production using low-cost biocompatible protic ionic liquids
journal, January 2017

Significantly enhancing enzymatic hydrolysis of rice straw after pretreatment using renewable ionic liquid–water mixtures
journal, May 2013

Loop vs. batch reactor setups in the fractionation of birch chips using switchable ionic liquids
journal, February 2014

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
journal, March 2012

PHA Recovery from Biomass
journal, August 2013

Scale-Up of Ionic Liquid-Based Fractionation of Single and Mixed Feedstocks
journal, February 2015

One-pot ionic liquid pretreatment and saccharification of switchgrass
journal, January 2013

Production of first and second generation biofuels: A comprehensive review
journal, February 2010

Scale-up and process integration of sugar production by acidolysis of municipal solid waste/corn stover blends in ionic liquids
journal, January 2017

Switchable Ionic Liquids as Delignification Solvents for Lignocellulosic Materials
journal, March 2014