Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system

doi:10.1016/j.actbio.2018.03.052

Title: Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system

Full Record
Other Related Research

Authors:: Wang, Yingwei; Zhang, Jianhua; Qin, Zixi; Fan, Zepei; Lu, Cheng; Chen, Baoxin; Zhao, Jupeng; Li, Xiaojuan; Xiao, Fei; Lin, Xi; Wu, Zheng

Publication Date:: 2018-05-01

Sponsoring Org.:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI Identifier:: 1548471

Grant/Contract Number:: 2014AA020534

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Acta Biomaterialia

Additional Journal Information:: Journal Name: Acta Biomaterialia Journal Volume: 72 Journal Issue: C; Journal ID: ISSN 1742-7061

Publisher:: Elsevier

Country of Publication:: Netherlands

Language:: English

Citation Formats


                    Wang, Yingwei, Zhang, Jianhua, Qin, Zixi, Fan, Zepei, Lu, Cheng, Chen, Baoxin, Zhao, Jupeng, Li, Xiaojuan, Xiao, Fei, Lin, Xi, and Wu, Zheng. Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system.  Netherlands: N. p., 2018. 
        Web.  doi:10.1016/j.actbio.2018.03.052.

Copy to clipboard


                    Wang, Yingwei, Zhang, Jianhua, Qin, Zixi, Fan, Zepei, Lu, Cheng, Chen, Baoxin, Zhao, Jupeng, Li, Xiaojuan, Xiao, Fei, Lin, Xi, & Wu, Zheng. Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system.  Netherlands.  doi:https://doi.org/10.1016/j.actbio.2018.03.052

Copy to clipboard


                    Wang, Yingwei, Zhang, Jianhua, Qin, Zixi, Fan, Zepei, Lu, Cheng, Chen, Baoxin, Zhao, Jupeng, Li, Xiaojuan, Xiao, Fei, Lin, Xi, and Wu, Zheng. Tue .  
        "Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system".  Netherlands.  doi:https://doi.org/10.1016/j.actbio.2018.03.052.

Copy to clipboard


                    
@article{osti_1548471,

  title        = {Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system},

  author       = {Wang, Yingwei and Zhang, Jianhua and Qin, Zixi and Fan, Zepei and Lu, Cheng and Chen, Baoxin and Zhao, Jupeng and Li, Xiaojuan and Xiao, Fei and Lin, Xi and Wu, Zheng},

  abstractNote = {},

  doi          = {10.1016/j.actbio.2018.03.052},

  journal      = {Acta Biomaterialia},

  number       = C,

  volume       = 72,

  place        = {Netherlands},

  year         = {2018},

  month        = {5}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Accepted Manuscript (Publisher)

Publisher's Version of Record
DOI: https://doi.org/10.1016/j.actbio.2018.03.052

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 3 works

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE PAGES and OSTI.GOV collections:

Dynamics of bone marrow-derived endothelial progenitor cell/mesenchymal stem cell interaction in co-culture and its implications in angiogenesis

Journal Article Aguirre, A. ; Planell, J. A. ; Dept. of Material Science and Metallurgical Engineering, Technical University of Catalonia ; ... - Biochemical and Biophysical Research Communications

Research highlights: {yields} BM-EPCs and MSCs establish complex, self-organizing structures in co-culture. {yields} Co-culture decreases proliferation by cellular self-regulatory mechanisms. {yields} Co-cultured cells present an activated proangiogenic phenotype. {yields} qRT-PCR and cluster analysis identify new target genes playing important roles. -- Abstract: Tissue engineering aims to regenerate tissues and organs by using cell and biomaterial-based approaches. One of the current challenges in the field is to promote proper vascularization in the implant to prevent cell death and promote host integration. Bone marrow endothelial progenitor cells (BM-EPCs) and mesenchymal stem cells (MSCs) are bone marrow resident stem cells widely employed formore »« less
DOI: https://doi.org/10.1016/J.BBRC.2010.08.073
Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine

Journal Article Tomar, Geetanjali B. ; Srivastava, Rupesh K. ; Gupta, Navita ; ... - Biochemical and Biophysical Research Communications

Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation into multiple cell lineages. Presently, bone marrow is considered as a prime source of MSCs; however, there are some drawbacks and limitations in use of these MSCs for cell therapy. In this study, we demonstrate that human gingival tissue-derived MSCs have several advantages over bone marrow-derived MSCs. Gingival MSCs are easy to isolate, homogenous and proliferate faster than bone marrow MSCs without any growth factor. Importantly, gingival MSCs display stable morphology and do not loose MSC characteristic at higher passages. In addition, gingival MSCs maintain normal karyotype and telomerase activitymore »« less
DOI: https://doi.org/10.1016/J.BBRC.2010.01.126
Enhanced cell survival and paracrine effects of mesenchymal stem cells overexpressing hepatocyte growth factor promote cardioprotection in myocardial infarction

Journal Article Zhao, Liyan ; Liu, Xiaolin ; Zhang, Yuelin ; ... - Experimental Cell Research

Poor cell survival post transplantation compromises the therapeutic benefits of mesenchymal stem cells (MSCs) in myocardial infarction (MI). Hepatocyte growth factor (HGF) is an important cytokine for angiogenesis, anti-inflammation and anti-apoptosis. This study aimed to evaluate the cardioprotective effects of MSCs overexpressing HGF in a mouse model of MI. The apoptosis of umbilical cord-derived MSCs (UC-MSCs) and HGF-UC-MSCs under normoxic and hypoxic conditions was detected. The conditioned medium (CdM) of UC-MSCs and HGF-UC-MSCs under a hypoxic condition was harvested and its protective effect on neonatal cardiomyocytes (NCMs) exposed to a hypoxic challenge was examined. UC-MSCs and HGF-UC-MSCs were transplanted intomore »« less
DOI: https://doi.org/10.1016/J.YEXCR.2016.03.024
Role of human amnion-derived mesenchymal stem cells in promoting osteogenic differentiation by influencing p38 MAPK signaling in lipopolysaccharide -induced human bone marrow mesenchymal stem cells

Journal Article Wang, Yuli ; Wu, Hongxia ; Shen, Ming ; ... - Experimental Cell Research

Periodontitis is a chronic inflammatory disease induced by bacterial pathogens, which not only affect connective tissue attachments but also cause alveolar bone loss. In this study, we investigated the anti-inflammatory effects of Human amnion-derived mesenchymal stem cells (HAMSCs) on human bone marrow mesenchymal stem cells (HBMSCs) under lipopolysaccharide (LPS)-induced inflammatory conditions. Proliferation levels were measured by flow cytometry and immunofluorescence staining of 5-ethynyl-2′-deoxyuridine (EdU). Osteoblastic differentiation and mineralization were investigated using chromogenic alkaline phosphatase activity (ALP) activity substrate assays, Alizarin red S staining, and RT-PCR analysis of HBMSCs osteogenic marker expression. Oxidative stress induced by LPS was investigated by assayingmore »« less
DOI: https://doi.org/10.1016/J.YEXCR.2016.11.003
Direct Write Assembly of Graphene/Poly(ε-Caprolactone) Composite Scaffolds and Evaluation of Their Biological Performance Using Mouse Bone Marrow Mesenchymal Stem Cells

Journal Article Deliormanlı, Aylin M., E-mail: aylin.deliormanli@cbu.edu.tr - Applied Biochemistry and Biotechnology

Scaffold and mesenchymal stem cell–based cartilage tissue engineering offers a favorable way for the repair and regeneration of injured cartilage. In this study, poly (ε-caprolactone) PCL scaffolds with grid-like structure having periodic lattice was manufactured by robocasting method in the presence of graphene nanoplatelets for cartilage tissue engineering applications. For this purpose, a PCL solution (20 wt%) containing pristine graphene nanopowders in the form of platelets was prepared as printing ink and it was dispensed through a nozzle at room temperature to an ethanol bath at 4 °C. The construction of porous scaffolds was made by a layer-by-layer assembly. Results revealed thatmore »« less
DOI: https://doi.org/10.1007/S12010-019-02976-5

Similar Records