DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Discrimination against RNA Backbones by a ssDNA Binding Protein

Authors:
;
Publication Date:
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
OSTI Identifier:
1548408
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Published Article
Journal Name:
Structure
Additional Journal Information:
Journal Name: Structure Journal Volume: 26 Journal Issue: 5; Journal ID: ISSN 0969-2126
Publisher:
Elsevier
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Lloyd, Neil R., and Wuttke, Deborah S. Discrimination against RNA Backbones by a ssDNA Binding Protein. United Kingdom: N. p., 2018. Web. doi:10.1016/j.str.2018.03.016.
Lloyd, Neil R., & Wuttke, Deborah S. Discrimination against RNA Backbones by a ssDNA Binding Protein. United Kingdom. https://doi.org/10.1016/j.str.2018.03.016
Lloyd, Neil R., and Wuttke, Deborah S. Tue . "Discrimination against RNA Backbones by a ssDNA Binding Protein". United Kingdom. https://doi.org/10.1016/j.str.2018.03.016.
@article{osti_1548408,
title = {Discrimination against RNA Backbones by a ssDNA Binding Protein},
author = {Lloyd, Neil R. and Wuttke, Deborah S.},
abstractNote = {},
doi = {10.1016/j.str.2018.03.016},
journal = {Structure},
number = 5,
volume = 26,
place = {United Kingdom},
year = {2018},
month = {5}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1016/j.str.2018.03.016

Citation Metrics:
Cited by: 1 work
Citation information provided by
Web of Science

Save / Share:

Works referenced in this record:

Universal rules and idiosyncratic features in tRNA identity
journal, November 1998


Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences
journal, August 2017


iMOSFLM : a new graphical interface for diffraction-image processing with MOSFLM
journal, March 2011

  • Battye, T. Geoff G.; Kontogiannis, Luke; Johnson, Owen
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444910048675

How Shelterin Protects Mammalian Telomeres
journal, December 2008


Overview of the CCP 4 suite and current developments
journal, March 2011

  • Winn, Martyn D.; Ballard, Charles C.; Cowtan, Kevin D.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444910045749

The telomeric transcriptome of Schizosaccharomyces pombe
journal, December 2011

  • Bah, Amadou; Wischnewski, Harry; Shchepachev, Vadim
  • Nucleic Acids Research, Vol. 40, Issue 7
  • DOI: 10.1093/nar/gkr1153

How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA
journal, December 2009

  • Nandakumar, Jayakrishnan; Podell, Elaine R.; Cech, Thomas R.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue 2
  • DOI: 10.1073/pnas.0911099107

Structural Basis of Single-Stranded RNA Recognition
journal, March 2004

  • Messias, Ana C.; Sattler, Michael
  • Accounts of Chemical Research, Vol. 37, Issue 5
  • DOI: 10.1021/ar030034m

Schizosaccharomyces pombe Protection of Telomeres 1 Utilizes Alternate Binding Modes To Accommodate Different Telomeric Sequences
journal, August 2011

  • Altschuler, Sarah E.; Dickey, Thayne H.; Wuttke, Deborah S.
  • Biochemistry, Vol. 50, Issue 35
  • DOI: 10.1021/bi200826a

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes
journal, November 2013

  • Lee, Michael; Hills, Mark; Conomos, Dimitri
  • Nucleic Acids Research, Vol. 42, Issue 3
  • DOI: 10.1093/nar/gkt1117

Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes
journal, January 2013


MolProbity : all-atom structure validation for macromolecular crystallography
journal, December 2009

  • Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1
  • DOI: 10.1107/S0907444909042073

Nucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexes
journal, August 2003


Features and development of Coot
journal, March 2010

  • Emsley, P.; Lohkamp, B.; Scott, W. G.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4
  • DOI: 10.1107/S0907444910007493

Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans
journal, May 2001


RNA recognition motifs: boring? Not quite
journal, June 2008

  • Cléry, Antoine; Blatter, Markus; Allain, Frédéric H-T
  • Current Opinion in Structural Biology, Vol. 18, Issue 3
  • DOI: 10.1016/j.sbi.2008.04.002

The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
journal, June 2010


Towards automated crystallographic structure refinement with phenix.refine
journal, March 2012

  • Afonine, Pavel V.; Grosse-Kunstleve, Ralf W.; Echols, Nathaniel
  • Acta Crystallographica Section D Biological Crystallography, Vol. 68, Issue 4
  • DOI: 10.1107/S0907444912001308

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
journal, August 2007

  • Denchi, Eros Lazzerini; de Lange, Titia
  • Nature, Vol. 448, Issue 7157
  • DOI: 10.1038/nature06065

PHENIX: a comprehensive Python-based system for macromolecular structure solution
journal, January 2010

  • Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221
  • DOI: 10.1107/S0907444909052925

An introduction to data reduction: space-group determination, scaling and intensity statistics
journal, March 2011

  • Evans, Philip R.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S090744491003982X

RNA regulatory networks diversified through curvature of the PUF protein scaffold
journal, September 2015

  • Wilinski, Daniel; Qiu, Chen; Lapointe, Christopher P.
  • Nature Communications, Vol. 6, Issue 1
  • DOI: 10.1038/ncomms9213

Origins of Specificity in Protein-DNA Recognition
journal, June 2010


Co-crystal structure of TBP recognizing the minor groove of a TATA element
journal, October 1993

  • Kim, Joseph L.; Nikolov, Dimitar B.; Burley, Stephen K.
  • Nature, Vol. 365, Issue 6446
  • DOI: 10.1038/365520a0

Site-Directed Mutagenesis Reveals the Thermodynamic Requirements for Single-Stranded DNA Recognition by the Telomere-Binding Protein Cdc13
journal, March 2003

  • Anderson, Emily M.; Halsey, Wayne A.; Wuttke, Deborah S.
  • Biochemistry, Vol. 42, Issue 13
  • DOI: 10.1021/bi027047c

From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold
journal, February 2004

  • Bochkarev, Alexey; Bochkareva, Elena
  • Current Opinion in Structural Biology, Vol. 14, Issue 1
  • DOI: 10.1016/j.sbi.2004.01.001

Escherichia Coli Single-Stranded DNA-Binding Protein: Multiple DNA-Binding Modes and Cooperativities
journal, June 1994


The telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3′ end availability
journal, July 2014

  • Dickey, Thayne H.; Wuttke, Deborah S.
  • Nucleic Acids Research, Vol. 42, Issue 15
  • DOI: 10.1093/nar/gku680

The Tetrahymena telomerase p75–p45–p19 subcomplex is a unique CST complex
journal, November 2015

  • Wan, Bingbing; Tang, Ting; Upton, Heather
  • Nature Structural & Molecular Biology, Vol. 22, Issue 12
  • DOI: 10.1038/nsmb.3126

Vertebrate POT1 Restricts G-Overhang Length and Prevents Activation of a Telomeric DNA Damage Checkpoint but Is Dispensable for Overhang Protection
journal, September 2006

  • Churikov, Dmitri; Wei, Chao; Price, Carolyn M.
  • Molecular and Cellular Biology, Vol. 26, Issue 18
  • DOI: 10.1128/MCB.01011-06

Themes in ssDNA recognition by telomere-end protection proteins
journal, September 2006


DNA–protein π-interactions in nature: abundance, structure, composition and strength of contacts between aromatic amino acids and DNA nucleobases or deoxyribose sugar
journal, April 2014

  • Wilson, Katie A.; Kellie, Jennifer L.; Wetmore, Stacey D.
  • Nucleic Acids Research, Vol. 42, Issue 10
  • DOI: 10.1093/nar/gku269

TER1, the RNA subunit of fission yeast telomerase
journal, December 2007

  • Leonardi, Jessica; Box, Jessica A.; Bunch, Jeremy T.
  • Nature Structural & Molecular Biology, Vol. 15, Issue 1
  • DOI: 10.1038/nsmb1343

Structure of DNA polymerase I Klenow fragment bound to duplex DNA
journal, April 1993


Nonadditivity in the Recognition of Single-Stranded DNA by the Schizosaccharomyces pombe Protection of Telomeres 1 DNA-Binding Domain, Pot1-DBD
journal, July 2009

  • Croy, Johnny E.; Altschuler, Sarah E.; Grimm, Nicole E.
  • Biochemistry, Vol. 48, Issue 29
  • DOI: 10.1021/bi900307x

DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
journal, November 2003

  • Lei, Ming; Podell, Elaine R.; Baumann, Peter
  • Nature, Vol. 426, Issue 6963
  • DOI: 10.1038/nature02092

Extended DNA Binding Site in Pot1 Broadens Sequence Specificity to Allow Recognition of Heterogeneous Fission Yeast Telomeres
journal, March 2005

  • Trujillo, Kelly M.; Bunch, Jeremy T.; Baumann, Peter
  • Journal of Biological Chemistry, Vol. 280, Issue 10
  • DOI: 10.1074/jbc.M414511200

Crystal structure of a yeast TBP/TATA-box complex
journal, October 1993

  • Kim, Youngchang; Geiger, James. H.; Hahn, Steven
  • Nature, Vol. 365, Issue 6446
  • DOI: 10.1038/365512a0

POT1 as a terminal transducer of TRF1 telomere length control
journal, May 2003


SOLVE and RESOLVE: automated structure solution, density modification and model building
journal, November 2003


Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Ion effects on ligand-nucleic acid interactions
journal, October 1976


How Telomeres Solve the End-Protection Problem
journal, November 2009


Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
journal, November 2004

  • Lei, Ming; Podell, Elaine R.; Cech, Thomas R.
  • Nature Structural & Molecular Biology, Vol. 11, Issue 12
  • DOI: 10.1038/nsmb867