A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner

doi:10.1002/mp.13724

Title: A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner

Authors:

Jiang, Jianyong ^[1]; Li, Ke ^[2]; Wang, Qiang ^[1]; Puterbaugh, Kenneth ^[3]; Young, John W. ^[3]; Siegel, Stefan B. ^[3]; O'Sullivan, Joseph A. ^[2]; Tai, Yuan‐Chuan ^[1]

Mallinckrodt Institute of Radiology, Washington University in St. Louis St. Louis MO 63110USA
Department of Electrical and Systems Engineering Washington University in St. Louis St. Louis MO 63130USA
Molecular Imaging Siemens Medical Solutions USA, Inc Knoxville TN 37932USA

Publication Date:: 2019-08-07

Sponsoring Org.:: USDOE

OSTI Identifier:: 1547606

Grant/Contract Number:: SC0005157

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Medical Physics

Additional Journal Information:: Journal Name: Medical Physics Journal Volume: 46 Journal Issue: 9; Journal ID: ISSN 0094-2405

Publisher:: Wiley Blackwell (John Wiley & Sons)

Country of Publication:: United States

Language:: English

Citation Formats


                    Jiang, Jianyong, Li, Ke, Wang, Qiang, Puterbaugh, Kenneth, Young, John W., Siegel, Stefan B., O'Sullivan, Joseph A., and Tai, Yuan‐Chuan. A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner.  United States: N. p., 2019. 
        Web.  doi:10.1002/mp.13724.

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                    Jiang, Jianyong, Li, Ke, Wang, Qiang, Puterbaugh, Kenneth, Young, John W., Siegel, Stefan B., O'Sullivan, Joseph A., & Tai, Yuan‐Chuan. A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner.  United States.  doi:10.1002/mp.13724.

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                    Jiang, Jianyong, Li, Ke, Wang, Qiang, Puterbaugh, Kenneth, Young, John W., Siegel, Stefan B., O'Sullivan, Joseph A., and Tai, Yuan‐Chuan. Wed .  
        "A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner".  United States.  doi:10.1002/mp.13724.

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@article{osti_1547606,

  title        = {A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner},

  author       = {Jiang, Jianyong and Li, Ke and Wang, Qiang and Puterbaugh, Kenneth and Young, John W. and Siegel, Stefan B. and O'Sullivan, Joseph A. and Tai, Yuan‐Chuan},

  abstractNote = {},

  doi          = {10.1002/mp.13724},

  journal      = {Medical Physics},

  number       = 9,

  volume       = 46,

  place        = {United States},

  year         = {2019},

  month        = {8}

}

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DOI: 10.1002/mp.13724

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Title: A second‐generation virtual‐pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole‐body PET/CT scanner

Citation Formats

Targeted multi-pinhole SPECT journal, November 2010

Feasibility study of a point‐of‐care positron emission tomography system with interactive imaging capability journal, February 2019

Clinical Imaging Characteristics of the Positron Emission Mammography Camera: PEM Flex Solo II journal, September 2009

Initial Characterization of a Dedicated Breast PET/CT Scanner During Human Imaging journal, August 2009

Study of a high-resolution PET system using a Silicon detector probe journal, September 2014

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Combined PET/MR Imaging — Technology and Applications journal, February 2010

GATE: A Geant4-Based Simulation Platform for PET and SPECT Integrating Movement and Time Management journal, October 2003

A High-Resolution PET Demonstrator using a Silicon “Magnifying Glass” journal, January 2012

Monitoring Tumor Response to Therapy with 18F-FLT PET journal, May 2010

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Adaptive Imaging for Lesion Detection Using a Zoom-in PET System journal, January 2011

A compact high resolution flat panel PET detector based on the new 4-side buttable MPPC for biomedical applications journal, September 2015

A combined time-of-flight and depth-of-interaction detector for total-body positron emission tomography: A combined time-of-flight and depth-of-interaction detector journal, January 2016

Performance evaluation of a very high resolution small animal PET imager using silicon scatter detectors journal, April 2007

Breast cancer detection using high-resolution breast PET compared to whole-body PET or PET/CT journal, October 2013

Micro Insert: A Prototype Full-Ring PET Device for Improving the Image Resolution of a Small-Animal PET Scanner journal, September 2008

Image reconstruction and system modeling techniques for virtual-pinhole PET insert systems journal, April 2012

Comparison of quantitative diagnostic tests: Type I error, power, and sample size journal, March 1987

Improving PET imaging for breast cancer using virtual pinhole PET half-ring insert journal, September 2013

Fully 3D list-mode time-of-flight PET image reconstruction on GPUs using CUDA: Fully 3D list-mode time-of-flight PET on GPU-CUDA journal, December 2011

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Radionuclide Methods and Instrumentation for Breast Cancer Detection and Diagnosis journal, July 2013

Virtual-Pinhole PET journal, February 2008

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Real time image reconstruction using GPUs for a surgical PET imaging probe system conference, October 2009

Update on Time-of-Flight PET Imaging journal, December 2014

Model-based normalization for iterative 3D PET image reconstruction journal, July 2002

Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care journal, September 2017

Clinical Performance of 2 Dedicated PET Scanners for Breast Imaging: Initial Evaluation journal, August 2012

Imaging of pulmonary mass lesions with whole-body positron emission tomography and fluorodeoxyglucose journal, July 1993

Performance Characteristics of a New LSO PET/CT Scanner With Extended Axial Field-of-View and PSF Reconstruction journal, June 2009

A simulation study for the design of a prototype insert for whole-body PET scanners journal, June 2006

Simple charge division readouts for imaging scintillator arrays using a multi-channel PMT journal, June 1996

Design of a very high-resolution small animal PET scanner using a silicon scatter detector insert journal, July 2007

Theoretical analysis and simulation study of a high-resolution zoom-in PET system journal, August 2009

Multi-resolution image reconstruction for a high-resolution small animal PET device conference, January 2003

Targeted multi-pinhole SPECT
journal, November 2010

Feasibility study of a point‐of‐care positron emission tomography system with interactive imaging capability
journal, February 2019

Clinical Imaging Characteristics of the Positron Emission Mammography Camera: PEM Flex Solo II
journal, September 2009

Initial Characterization of a Dedicated Breast PET/CT Scanner During Human Imaging
journal, August 2009

Study of a high-resolution PET system using a Silicon detector probe
journal, September 2014

Role of Positron Emission Tomography for the Monitoring of Response to Therapy in Breast Cancer
journal, January 2015

Combined PET/MR Imaging — Technology and Applications
journal, February 2010

GATE: A Geant4-Based Simulation Platform for PET and SPECT Integrating Movement and Time Management
journal, October 2003

A High-Resolution PET Demonstrator using a Silicon “Magnifying Glass”
journal, January 2012

Monitoring Tumor Response to Therapy with 18F-FLT PET
journal, May 2010

Fast List-Mode Reconstruction for Time-of-Flight PET Using Graphics Hardware
journal, February 2011

Adaptive Imaging for Lesion Detection Using a Zoom-in PET System
journal, January 2011

A compact high resolution flat panel PET detector based on the new 4-side buttable MPPC for biomedical applications
journal, September 2015

A combined time-of-flight and depth-of-interaction detector for total-body positron emission tomography: A combined time-of-flight and depth-of-interaction detector
journal, January 2016

Performance evaluation of a very high resolution small animal PET imager using silicon scatter detectors
journal, April 2007

Breast cancer detection using high-resolution breast PET compared to whole-body PET or PET/CT
journal, October 2013

Micro Insert: A Prototype Full-Ring PET Device for Improving the Image Resolution of a Small-Animal PET Scanner
journal, September 2008

Image reconstruction and system modeling techniques for virtual-pinhole PET insert systems
journal, April 2012

Comparison of quantitative diagnostic tests: Type I error, power, and sample size
journal, March 1987

Improving PET imaging for breast cancer using virtual pinhole PET half-ring insert
journal, September 2013

Fully 3D list-mode time-of-flight PET image reconstruction on GPUs using CUDA: Fully 3D list-mode time-of-flight PET on GPU-CUDA
journal, December 2011

Positron emission tomography with fluorine-18-deoxyglucose in the detection and staging of breast cancer
journal, June 1993

Radionuclide Methods and Instrumentation for Breast Cancer Detection and Diagnosis
journal, July 2013

Virtual-Pinhole PET
journal, February 2008

An evaluation of polygraphers' judgments: A review from a decision theoretic perspective.
journal, January 1982

A silicon PET probe
journal, August 2011

Real time image reconstruction using GPUs for a surgical PET imaging probe system
conference, October 2009

Update on Time-of-Flight PET Imaging
journal, December 2014

Model-based normalization for iterative 3D PET image reconstruction
journal, July 2002

Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care
journal, September 2017

Clinical Performance of 2 Dedicated PET Scanners for Breast Imaging: Initial Evaluation
journal, August 2012

Imaging of pulmonary mass lesions with whole-body positron emission tomography and fluorodeoxyglucose
journal, July 1993

Performance Characteristics of a New LSO PET/CT Scanner With Extended Axial Field-of-View and PSF Reconstruction
journal, June 2009

A simulation study for the design of a prototype insert for whole-body PET scanners
journal, June 2006

Simple charge division readouts for imaging scintillator arrays using a multi-channel PMT
journal, June 1996

Design of a very high-resolution small animal PET scanner using a silicon scatter detector insert
journal, July 2007

Theoretical analysis and simulation study of a high-resolution zoom-in PET system
journal, August 2009

Multi-resolution image reconstruction for a high-resolution small animal PET device
conference, January 2003