skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

This content will become publicly available on July 28, 2020

Title: Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development

Authors:
 [1];  [1];  [1];  [2]
  1. Department of Gynecology and ObstetricsAdnan Menderes University, Faculty of Medicine Aydin Turkey
  2. Intergen Genetics Center Ankara Turkey
Publication Date:
Sponsoring Org.:
USDOE Office of Environmental Management (EM), Acquisition and Project Management (EM-50)
OSTI Identifier:
1545479
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Journal of Obstetrics and Gynaecology Research
Additional Journal Information:
Journal Name: Journal of Obstetrics and Gynaecology Research Journal Volume: 45 Journal Issue: 10; Journal ID: ISSN 1341-8076
Publisher:
Wiley-Blackwell
Country of Publication:
Country unknown/Code not available
Language:
English

Citation Formats

Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., and Ceylaner, Serdar. Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development. Country unknown/Code not available: N. p., 2019. Web. doi:10.1111/jog.14071.
Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., & Ceylaner, Serdar. Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development. Country unknown/Code not available. doi:10.1111/jog.14071.
Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., and Ceylaner, Serdar. Mon . "Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development". Country unknown/Code not available. doi:10.1111/jog.14071.
@article{osti_1545479,
title = {Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development},
author = {Altinkaya, S. Ozlem and Avcioglu, Sumeyra N. and Sezer, Selda D. and Ceylaner, Serdar},
abstractNote = {},
doi = {10.1111/jog.14071},
journal = {Journal of Obstetrics and Gynaecology Research},
number = 10,
volume = 45,
place = {Country unknown/Code not available},
year = {2019},
month = {7}
}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on July 28, 2020
Publisher's Version of Record

Save / Share:

Works referenced in this record:

Tumor necrosis factor-α-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas
journal, October 2004


Rearrangement of the p53 gene in human osteogenic sarcomas.
journal, November 1987

  • Masuda, H.; Miller, C.; Koeffler, H. P.
  • Proceedings of the National Academy of Sciences, Vol. 84, Issue 21
  • DOI: 10.1073/pnas.84.21.7716

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
journal, December 2014

  • Wong, Terrence N.; Ramsingh, Giridharan; Young, Andrew L.
  • Nature, Vol. 518, Issue 7540
  • DOI: 10.1038/nature13968

Epidemiologic Contributions to Understanding the Etiology of Uterine Leiomyomata
journal, October 2000

  • Schwartz, Stephen M.; Marshall, Lynn M.; Baird, Donna D.
  • Environmental Health Perspectives, Vol. 108, Issue s5
  • DOI: 10.1289/ehp.00108s5821

Polymorphism of the p53 tumor suppressor gene is associated with susceptibility to uterine leiomyoma
journal, July 2005


The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction
journal, March 2016


A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
journal, September 2011

  • Stacey, Simon N.; Sulem, Patrick; Jonasdottir, Aslaug
  • Nature Genetics, Vol. 43, Issue 11
  • DOI: 10.1038/ng.926

Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression
journal, September 2013

  • Ortega, F. J.; Moreno-Navarrete, J. M.; Mayas, D.
  • International Journal of Obesity, Vol. 38, Issue 5
  • DOI: 10.1038/ijo.2013.163

Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer.
journal, May 1991

  • Chen, L. C.; Neubauer, A.; Kurisu, W.
  • Proceedings of the National Academy of Sciences, Vol. 88, Issue 9
  • DOI: 10.1073/pnas.88.9.3847

Germline Mutations of the p53 Tumor-Suppressor Gene in Children and Young Adults with Second Malignant Neoplasms
journal, May 1992


The role of p53 in cancer drug resistance and targeted chemotherapy
journal, November 2016


Putting p53 in Context
journal, September 2017


Apoptosis and aging: breast cells and apoptosis
journal, February 2001


Analysis of Ki-ras, p53, and MDM2 Genes in Uterine Leiomyomas and Leiomyosarcomas
journal, May 1997

  • Hall, Kevin L.; Teneriello, Michael G.; Taylor, Robert R.
  • Gynecologic Oncology, Vol. 65, Issue 2
  • DOI: 10.1006/gyno.1997.4653

An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.
journal, July 1992

  • Sun, Y.; Hegamyer, G.; Cheng, Y. J.
  • Proceedings of the National Academy of Sciences, Vol. 89, Issue 14
  • DOI: 10.1073/pnas.89.14.6516

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines
journal, January 2006

  • Liu, Y.; Bodmer, W. F.
  • Proceedings of the National Academy of Sciences, Vol. 103, Issue 4
  • DOI: 10.1073/pnas.0510146103

Gene and protein expression of progesterone receptor isoforms A and B, p53 and p21 in myometrium and uterine leiomyoma
journal, February 2012

  • Lora, Vanessa; Grings, Anelise Olmos; Capp, Edison
  • Archives of Gynecology and Obstetrics, Vol. 286, Issue 1
  • DOI: 10.1007/s00404-012-2245-2

TP53 polymorphism in plasma cell myeloma
journal, February 2018

  • Zmorzynski, Szymon Andrzej; Korszen-Pilecka, Iwona; Wojcierowska-Litwin, Magdalena
  • Folia Histochemica et Cytobiologica, Vol. 55, Issue 4
  • DOI: 10.5603/FHC.a2017.0022

Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis
journal, December 2006


Four novel single nucleotide polymorphisms within the promoter region of p53 gene and their associations with uterine leiomyoma
journal, January 2007

  • Hsieh, Yao-Yuan; Wang, Jui-Ping; Lin, Chich-Sheng
  • Molecular Reproduction and Development, Vol. 74, Issue 7
  • DOI: 10.1002/mrd.20464

Apoptosis in Human Uterine Leiomyomas
journal, May 2004


Melanoma arising in a Giant congenital melanocytic nevus: two case reports
journal, February 2019

  • Belysheva, Tatiana S.; Vishnevskaya, Yana V.; Nasedkina, Tatiana V.
  • Diagnostic Pathology, Vol. 14, Issue 1
  • DOI: 10.1186/s13000-019-0797-1

Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis of glucose-6-phosphate dehydrogenase
journal, January 1970

  • Townsend, Duane E.; Sparkes, Roberts.; Baluda, Maryellen C.
  • American Journal of Obstetrics and Gynecology, Vol. 107, Issue 8
  • DOI: 10.1016/S0002-9378(15)30365-3

Why are there hotspot mutations in the TP53 gene in human cancers?
journal, November 2017

  • Baugh, Evan H.; Ke, Hua; Levine, Arnold J.
  • Cell Death & Differentiation, Vol. 25, Issue 1
  • DOI: 10.1038/cdd.2017.180

Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma - A case-control study
journal, November 2015


p53 Mutations are common in pancreatic cancer and are absent in chronic pancreatitis
journal, May 1993


Mutation analysis ofCDP,TP53, andKRAS in uterine leiomyomas
journal, May 2003

  • Patrikis, Maria I.; Bryan, Emma J.; Thomas, Nicola A.
  • Molecular Carcinogenesis, Vol. 37, Issue 2
  • DOI: 10.1002/mc.10127

Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors
journal, August 2016


Mutational hot spot in the p53 gene in human hepatocellular carcinomas
journal, April 1991

  • Hsu, I. C.; Metcalf, R. A.; Sun, T.
  • Nature, Vol. 350, Issue 6317
  • DOI: 10.1038/350427a0

Prognostic Significance of TP53 Mutations and Single Nucleotide Polymorphisms in Acute Myeloid Leukemia: A case Series and Literature Review
journal, February 2014

  • Zeichner, Simon Blechman; Alghamdi, Sarah; Elhammady, Gina
  • Asian Pacific Journal of Cancer Prevention, Vol. 15, Issue 4
  • DOI: 10.7314/APJCP.2014.15.4.1603

Tumor suppressive role for kinases phosphorylating p53 in DNA damage-induced apoptosis
journal, October 2018

  • Yogosawa, Satomi; Yoshida, Kiyotsugu
  • Cancer Science, Vol. 109, Issue 11
  • DOI: 10.1111/cas.13792

Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma
journal, June 2008

  • Russell-Swetek, A.; West, A. N.; Mintern, J. E.
  • Journal of Medical Genetics, Vol. 45, Issue 9
  • DOI: 10.1136/jmg.2008.059568

A crucial role for adipose tissue p53 in the regulation of insulin resistance
journal, August 2009

  • Minamino, Tohru; Orimo, Masayuki; Shimizu, Ippei
  • Nature Medicine, Vol. 15, Issue 9
  • DOI: 10.1038/nm.2014

Absence of p53-Dependent Apoptosis Combined With Nonhomologous End-Joining Deficiency Leads to a Severe Diabetic Phenotype in Mice
journal, October 2009

  • Tavana, O.; Puebla-Osorio, N.; Sang, M.
  • Diabetes, Vol. 59, Issue 1
  • DOI: 10.2337/db09-0792