Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development

doi:10.1111/jog.14071

This content will become publicly available on July 28, 2020

Title: Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development

Authors:

Altinkaya, S. Ozlem ^[1]; Avcioglu, Sumeyra N. ^[1]; Sezer, Selda D. ^[1]; Ceylaner, Serdar ^[2]

Department of Gynecology and ObstetricsAdnan Menderes University, Faculty of Medicine Aydin Turkey
Intergen Genetics Center Ankara Turkey

Publication Date:: 2019-07-29

Sponsoring Org.:: USDOE Office of Environmental Management (EM), Acquisition and Project Management (EM-50)

OSTI Identifier:: 1545479

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Journal of Obstetrics and Gynaecology Research

Additional Journal Information:: Journal Name: Journal of Obstetrics and Gynaecology Research Journal Volume: 45 Journal Issue: 10; Journal ID: ISSN 1341-8076

Publisher:: Wiley-Blackwell

Country of Publication:: Country unknown/Code not available

Language:: English

Citation Formats


                    Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., and Ceylaner, Serdar. Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development.  Country unknown/Code not available: N. p., 2019. 
        Web.  doi:10.1111/jog.14071.

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                    Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., & Ceylaner, Serdar. Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development.  Country unknown/Code not available.  doi:10.1111/jog.14071.

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                    Altinkaya, S. Ozlem, Avcioglu, Sumeyra N., Sezer, Selda D., and Ceylaner, Serdar. Mon .  
        "Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development".  Country unknown/Code not available.  doi:10.1111/jog.14071.

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@article{osti_1545479,

  title        = {Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development},

  author       = {Altinkaya, S. Ozlem and Avcioglu, Sumeyra N. and Sezer, Selda D. and Ceylaner, Serdar},

  abstractNote = {},

  doi          = {10.1111/jog.14071},

  journal      = {Journal of Obstetrics and Gynaecology Research},

  number       = 10,

  volume       = 45,

  place        = {Country unknown/Code not available},

  year         = {2019},

  month        = {7}

}

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DOI: 10.1111/jog.14071

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Similar Records

This content will become publicly available on July 28, 2020

Title: Analysis of TP53 gene in uterine myomas: No mutations but P72R polymorphism is associated with myoma development

Citation Formats

Tumor necrosis factor-α-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas journal, October 2004

Rearrangement of the p53 gene in human osteogenic sarcomas. journal, November 1987

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia journal, December 2014

Epidemiologic Contributions to Understanding the Etiology of Uterine Leiomyomata journal, October 2000

Polymorphism of the p53 tumor suppressor gene is associated with susceptibility to uterine leiomyoma journal, July 2005

The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction journal, March 2016

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility journal, September 2011

Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression journal, September 2013

Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer. journal, May 1991

Germline Mutations of the p53 Tumor-Suppressor Gene in Children and Young Adults with Second Malignant Neoplasms journal, May 1992

The role of p53 in cancer drug resistance and targeted chemotherapy journal, November 2016

Putting p53 in Context journal, September 2017

Apoptosis and aging: breast cells and apoptosis journal, February 2001

Analysis of Ki-ras, p53, and MDM2 Genes in Uterine Leiomyomas and Leiomyosarcomas journal, May 1997

An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma. journal, July 1992

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines journal, January 2006

Gene and protein expression of progesterone receptor isoforms A and B, p53 and p21 in myometrium and uterine leiomyoma journal, February 2012

Molecular analyses of 6 different types of uterine smooth muscle tumors: Emphasis in atypical leiomyoma: Analysis of Uterine Smooth Muscle Tumors journal, July 2014

TP53 polymorphism in plasma cell myeloma journal, February 2018

Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis journal, December 2006

Four novel single nucleotide polymorphisms within the promoter region of p53 gene and their associations with uterine leiomyoma journal, January 2007

Apoptosis in Human Uterine Leiomyomas journal, May 2004

Melanoma arising in a Giant congenital melanocytic nevus: two case reports journal, February 2019

Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis of glucose-6-phosphate dehydrogenase journal, January 1970

Why are there hotspot mutations in the TP53 gene in human cancers? journal, November 2017

Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma - A case-control study journal, November 2015

p53 Mutations are common in pancreatic cancer and are absent in chronic pancreatitis journal, May 1993

Mutation analysis ofCDP,TP53, andKRAS in uterine leiomyomas journal, May 2003

Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors journal, August 2016

Mutational hot spot in the p53 gene in human hepatocellular carcinomas journal, April 1991

Prognostic Significance of TP53 Mutations and Single Nucleotide Polymorphisms in Acute Myeloid Leukemia: A case Series and Literature Review journal, February 2014

Tumor suppressive role for kinases phosphorylating p53 in DNA damage-induced apoptosis journal, October 2018

Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma journal, June 2008

A crucial role for adipose tissue p53 in the regulation of insulin resistance journal, August 2009

Absence of p53-Dependent Apoptosis Combined With Nonhomologous End-Joining Deficiency Leads to a Severe Diabetic Phenotype in Mice journal, October 2009

Tumor necrosis factor-α-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas
journal, October 2004

Rearrangement of the p53 gene in human osteogenic sarcomas.
journal, November 1987

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
journal, December 2014

Epidemiologic Contributions to Understanding the Etiology of Uterine Leiomyomata
journal, October 2000

Polymorphism of the p53 tumor suppressor gene is associated with susceptibility to uterine leiomyoma
journal, July 2005

The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction
journal, March 2016

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
journal, September 2011

Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression
journal, September 2013

Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer.
journal, May 1991

Germline Mutations of the p53 Tumor-Suppressor Gene in Children and Young Adults with Second Malignant Neoplasms
journal, May 1992

The role of p53 in cancer drug resistance and targeted chemotherapy
journal, November 2016

Putting p53 in Context
journal, September 2017

Apoptosis and aging: breast cells and apoptosis
journal, February 2001

Analysis of Ki-ras, p53, and MDM2 Genes in Uterine Leiomyomas and Leiomyosarcomas
journal, May 1997

An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.
journal, July 1992

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines
journal, January 2006

Gene and protein expression of progesterone receptor isoforms A and B, p53 and p21 in myometrium and uterine leiomyoma
journal, February 2012

Molecular analyses of 6 different types of uterine smooth muscle tumors: Emphasis in atypical leiomyoma: Analysis of Uterine Smooth Muscle Tumors
journal, July 2014

TP53 polymorphism in plasma cell myeloma
journal, February 2018

Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis
journal, December 2006

Four novel single nucleotide polymorphisms within the promoter region of p53 gene and their associations with uterine leiomyoma
journal, January 2007

Apoptosis in Human Uterine Leiomyomas
journal, May 2004

Melanoma arising in a Giant congenital melanocytic nevus: two case reports
journal, February 2019

Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis of glucose-6-phosphate dehydrogenase
journal, January 1970

Why are there hotspot mutations in the TP53 gene in human cancers?
journal, November 2017

Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma - A case-control study
journal, November 2015

p53 Mutations are common in pancreatic cancer and are absent in chronic pancreatitis
journal, May 1993

Mutation analysis ofCDP,TP53, andKRAS in uterine leiomyomas
journal, May 2003

Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors
journal, August 2016

Mutational hot spot in the p53 gene in human hepatocellular carcinomas
journal, April 1991

Prognostic Significance of TP53 Mutations and Single Nucleotide Polymorphisms in Acute Myeloid Leukemia: A case Series and Literature Review
journal, February 2014

Tumor suppressive role for kinases phosphorylating p53 in DNA damage-induced apoptosis
journal, October 2018

Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma
journal, June 2008

A crucial role for adipose tissue p53 in the regulation of insulin resistance
journal, August 2009

Absence of p53-Dependent Apoptosis Combined With Nonhomologous End-Joining Deficiency Leads to a Severe Diabetic Phenotype in Mice
journal, October 2009