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Title: Genomics of the origin and evolution of Citrus

Abstract

The genus Citrus, comprising some of the most widely cultivated fruit crops worldwide, includes an uncertain number of species. Here we describe ten natural citrus species, using genomic, phylogenetic and biogeographic analyses of 60 accessions representing diverse citrus germ plasms, and propose that citrus diversified during the late Miocene epoch through a rapid southeast Asian radiation that correlates with a marked weakening of the monsoons. A second radiation enabled by migration across the Wallace line gave rise to the Australian limes in the early Pliocene epoch. Further identification and analyses of hybrids and admixed genomes provides insights into the genealogy of major commercial cultivars of citrus. Among mandarins and sweet orange, we find an extensive network of relatedness that illuminates the domestication of these groups. Widespread pummelo admixture among these mandarins and its correlation with fruit size and acidity suggests a plausible role of pummelo introgression in the selection of palatable mandarins. This work provides a new evolutionary framework for the genus Citrus.

Authors:
 [1];  [2];  [2];  [2];  [2];  [2];  [2];  [2];  [3];  [3];  [4];  [5];  [6];  [7];  [8];  [5];  [9];  [2]
  1. USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
  2. Inst. Valenciano de Investigaciones Agrarias (IVIA), Moncada, Valencia (Spain). Centro de Genómica
  3. Centro de Investigación Príncipe Felipe (CIPF), Valencia (Spain)
  4. Inst. National de la Recherche Agronomique (INRA), San Giuliano (France)
  5. Univ. of Florida, Lake Alfred, FL (United States). Inst. of Food and Agricultural Sciences (IFAS)
  6. AGAP Research Unit, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Petit-Bourg, Guadeloupe (France)
  7. Univ. of California, Riverside, CA (United States)
  8. Centro de Investigación Príncipe Felipe (CIPF), Valencia (Spain); Spanish National Inst. of Bioinformatics (ELIXIR-es) at CIPF, Valencia (Spain)
  9. USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Univ. of California, Berkeley, CA (United States); Okinawa Inst. of Science and Technology Graduate Univ., Onna, Okinawa (Japan)
Publication Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC)
Sponsoring Org.:
USDOE
OSTI Identifier:
1543733
Resource Type:
Accepted Manuscript
Journal Name:
Nature (London)
Additional Journal Information:
Journal Name: Nature (London); Journal Volume: 554; Journal Issue: 7692; Journal ID: ISSN 0028-0836
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; Science & Technology - Other Topics

Citation Formats

Wu, Guohong Albert, Terol, Javier, Ibanez, Victoria, López-García, Antonio, Pérez-Román, Estela, Borredá, Carles, Domingo, Concha, Tadeo, Francisco R., Carbonell-Caballero, Jose, Alonso, Roberto, Curk, Franck, Du, Dongliang, Ollitrault, Patrick, Roose, Mikeal L., Dopazo, Joaquin, Gmitter, Frederick G., Rokhsar, Daniel S., and Talon, Manuel. Genomics of the origin and evolution of Citrus. United States: N. p., 2018. Web. doi:10.1038/nature25447.
Wu, Guohong Albert, Terol, Javier, Ibanez, Victoria, López-García, Antonio, Pérez-Román, Estela, Borredá, Carles, Domingo, Concha, Tadeo, Francisco R., Carbonell-Caballero, Jose, Alonso, Roberto, Curk, Franck, Du, Dongliang, Ollitrault, Patrick, Roose, Mikeal L., Dopazo, Joaquin, Gmitter, Frederick G., Rokhsar, Daniel S., & Talon, Manuel. Genomics of the origin and evolution of Citrus. United States. https://doi.org/10.1038/nature25447
Wu, Guohong Albert, Terol, Javier, Ibanez, Victoria, López-García, Antonio, Pérez-Román, Estela, Borredá, Carles, Domingo, Concha, Tadeo, Francisco R., Carbonell-Caballero, Jose, Alonso, Roberto, Curk, Franck, Du, Dongliang, Ollitrault, Patrick, Roose, Mikeal L., Dopazo, Joaquin, Gmitter, Frederick G., Rokhsar, Daniel S., and Talon, Manuel. Thu . "Genomics of the origin and evolution of Citrus". United States. https://doi.org/10.1038/nature25447. https://www.osti.gov/servlets/purl/1543733.
@article{osti_1543733,
title = {Genomics of the origin and evolution of Citrus},
author = {Wu, Guohong Albert and Terol, Javier and Ibanez, Victoria and López-García, Antonio and Pérez-Román, Estela and Borredá, Carles and Domingo, Concha and Tadeo, Francisco R. and Carbonell-Caballero, Jose and Alonso, Roberto and Curk, Franck and Du, Dongliang and Ollitrault, Patrick and Roose, Mikeal L. and Dopazo, Joaquin and Gmitter, Frederick G. and Rokhsar, Daniel S. and Talon, Manuel},
abstractNote = {The genus Citrus, comprising some of the most widely cultivated fruit crops worldwide, includes an uncertain number of species. Here we describe ten natural citrus species, using genomic, phylogenetic and biogeographic analyses of 60 accessions representing diverse citrus germ plasms, and propose that citrus diversified during the late Miocene epoch through a rapid southeast Asian radiation that correlates with a marked weakening of the monsoons. A second radiation enabled by migration across the Wallace line gave rise to the Australian limes in the early Pliocene epoch. Further identification and analyses of hybrids and admixed genomes provides insights into the genealogy of major commercial cultivars of citrus. Among mandarins and sweet orange, we find an extensive network of relatedness that illuminates the domestication of these groups. Widespread pummelo admixture among these mandarins and its correlation with fruit size and acidity suggests a plausible role of pummelo introgression in the selection of palatable mandarins. This work provides a new evolutionary framework for the genus Citrus.},
doi = {10.1038/nature25447},
journal = {Nature (London)},
number = 7692,
volume = 554,
place = {United States},
year = {Thu Feb 01 00:00:00 EST 2018},
month = {Thu Feb 01 00:00:00 EST 2018}
}

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Works referenced in this record:

On the History and Origin of Citrus
journal, November 1975

  • Scora, Rainer W.
  • Bulletin of the Torrey Botanical Club, Vol. 102, Issue 6
  • DOI: 10.2307/2484763

Southeast Asia's changing palaeogeography
journal, October 2009


Estimating Absolute Rates of Molecular Evolution and Divergence Times: A Penalized Likelihood Approach
journal, January 2002


Genetic structure and domestication history of the grape
journal, January 2011

  • Myles, Sean; Boyko, Adam R.; Owens, Christopher L.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 9
  • DOI: 10.1073/pnas.1009363108

The draft genome of sweet orange (Citrus sinensis)
journal, November 2012

  • Xu, Qiang; Chen, Ling-Ling; Ruan, Xiaoan
  • Nature Genetics, Vol. 45, Issue 1
  • DOI: 10.1038/ng.2472

From forest to field: Perennial fruit crop domestication
journal, September 2011

  • Miller, Allison J.; Gross, Briana L.
  • American Journal of Botany, Vol. 98, Issue 9
  • DOI: 10.3732/ajb.1000522

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
journal, March 2010

  • Guindon, Stéphane; Dufayard, Jean-François; Lefort, Vincent
  • Systematic Biology, Vol. 59, Issue 3
  • DOI: 10.1093/sysbio/syq010

Genome-wide efficient mixed-model analysis for association studies
journal, June 2012

  • Zhou, Xiang; Stephens, Matthew
  • Nature Genetics, Vol. 44, Issue 7
  • DOI: 10.1038/ng.2310

The age and biogeography of Citrus and the orange subfamily (Rutaceae: Aurantioideae) in Australasia and New Caledonia
journal, December 2008

  • Pfeil, Bernard E.; Crisp, Michael D.
  • American Journal of Botany, Vol. 95, Issue 12
  • DOI: 10.3732/ajb.0800214

Hybrid Origins of Citrus Varieties Inferred from DNA Marker Analysis of Nuclear and Organelle Genomes
journal, November 2016


Population genetics of genomics-based crop improvement methods
journal, March 2011

  • Hamblin, Martha T.; Buckler, Edward S.; Jannink, Jean-Luc
  • Trends in Genetics, Vol. 27, Issue 3
  • DOI: 10.1016/j.tig.2010.12.003

Citrus linczangensis sp. n., a Leaf Fossil of Rutaceae from the Late Miocene of Yunnan, China
journal, October 2013

  • Xie, Sanping; Manchester, Steven R.; Liu, Kenan
  • International Journal of Plant Sciences, Vol. 174, Issue 8
  • DOI: 10.1086/671796

The Leaf Oils of the Australian Species of Citrus (Rutaceae)
journal, July 2001

  • Brophy, Joseph J.; Goldsack, Robert J.; Forster, Paul I.
  • Journal of Essential Oil Research, Vol. 13, Issue 4
  • DOI: 10.1080/10412905.2001.9699690

The role of the uplift of the Qinghai-Tibetan Plateau for the evolution of Tibetan biotas: Evolution of Tibetan biotas
journal, May 2014

  • Favre, Adrien; Päckert, Martin; Pauls, Steffen U.
  • Biological Reviews, Vol. 90, Issue 1
  • DOI: 10.1111/brv.12107

Fast and accurate long-read alignment with Burrows–Wheeler transform
journal, January 2010


Genomic analyses of primitive, wild and cultivated citrus provide insights into asexual reproduction
journal, April 2017

  • Wang, Xia; Xu, Yuantao; Zhang, Siqi
  • Nature Genetics, Vol. 49, Issue 5
  • DOI: 10.1038/ng.3839

The possible role of Yunnan, China, in the origin of contemporary citrus species (rutaceae)
journal, April 1990

  • Gmitter, Frederick G.; Hu, Xulan
  • Economic Botany, Vol. 44, Issue 2
  • DOI: 10.1007/BF02860491

Emergence and evolution of Himalaya: reconstructing history in the light of recent studies
journal, September 2002


Phylogeography of plants in Taiwan and the Ryukyu Archipelago
journal, February 2006

  • Chiang, Tzen-Yuh; Schaal, Barbara A.
  • TAXON, Vol. 55, Issue 1
  • DOI: 10.2307/25065526

Global chronostratigraphical correlation table for the last 2.7 million years
journal, June 2008


Quantitative reconstruction of the Late Miocene monsoon climates of southwest China: A case study of the Lincang flora from Yunnan Province
journal, May 2011

  • Jacques, Frédéric M. B.; Guo, Shuang-Xing; Su, Tao
  • Palaeogeography, Palaeoclimatology, Palaeoecology, Vol. 304, Issue 3-4
  • DOI: 10.1016/j.palaeo.2010.04.014

Han Yen-Chih's Chü Lu
journal, January 1923


Phylogenetic origin of limes and lemons revealed by cytoplasmic and nuclear markers
journal, March 2016

  • Curk, Franck; Ollitrault, Frédérique; Garcia-Lor, Andres
  • Annals of Botany, Vol. 117, Issue 4
  • DOI: 10.1093/aob/mcw005

New Insight into the History of Domesticated Apple: Secondary Contribution of the European Wild Apple to the Genome of Cultivated Varieties
journal, May 2012


A Survey and Isozyme Analysis of Wild Mandarin, Tachibana (Citrus tachibana (Mak.) Tanaka) Growing in Japan [日本におけるタチバナ (Citrus tachibana (Mak.) Tanaka) の分布とアイソザイム分析]
journal, January 1990

  • Hirai, Masashi; Mitsue, Shuichi; Kita, Keiji
  • Journal of the Japanese Society for Horticultural Science, Vol. 59, Issue 1
  • DOI: 10.2503/jjshs.59.1

The Genomic Signature of Crop-Wild Introgression in Maize
journal, May 2013


The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
journal, July 2010


MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space
journal, February 2012

  • Ronquist, Fredrik; Teslenko, Maxim; van der Mark, Paul
  • Systematic Biology, Vol. 61, Issue 3
  • DOI: 10.1093/sysbio/sys029

Citrus phylogeny and genetic origin of important species as investigated by molecular markers
journal, June 2000

  • Nicolosi, E.; Deng, Z. N.; Gentile, A.
  • Theoretical and Applied Genetics, Vol. 100, Issue 8
  • DOI: 10.1007/s001220051419

Maps of Pleistocene sea levels in Southeast Asia: shorelines, river systems and time durations
journal, September 2000


A molecular phylogeny of the orange subfamily(Rutaceae: Aurantioideae) using nine cpDNA sequences
journal, March 2009

  • Bayer, Randall J.; Mabberley, David J.; Morton, Cynthia
  • American Journal of Botany, Vol. 96, Issue 3
  • DOI: 10.3732/ajb.0800341

Archaeological and genetic insights into the origins of domesticated rice
journal, April 2014

  • Gross, B. L.; Zhao, Z.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 17
  • DOI: 10.1073/pnas.1308942110

APE: Analyses of Phylogenetics and Evolution in R language
journal, January 2004


A Numerical Taxonomic Study of Affinity Relationships in Cultivated Citrus and Its Close Relatives
journal, July 1976

  • Barrett, H. C.; Rhodes, A. M.
  • Systematic Botany, Vol. 1, Issue 2
  • DOI: 10.2307/2418763

Sequencing of diverse mandarin, pummelo and orange genomes reveals complex history of admixture during citrus domestication
journal, June 2014

  • Wu, G. Albert; Prochnik, Simon; Jenkins, Jerry
  • Nature Biotechnology, Vol. 32, Issue 7
  • DOI: 10.1038/nbt.2906

Late Miocene southwestern Chinese floristic diversity shaped by the southeastern uplift of the Tibetan Plateau
journal, October 2014

  • Jacques, Frédéric M. B.; Su, Tao; Spicer, Robert A.
  • Palaeogeography, Palaeoclimatology, Palaeoecology, Vol. 411
  • DOI: 10.1016/j.palaeo.2014.05.041

Genomics and the Contrasting Dynamics of Annual and Perennial Domestication
journal, December 2015

  • Gaut, Brandon S.; Díez, Concepción M.; Morrell, Peter L.
  • Trends in Genetics, Vol. 31, Issue 12
  • DOI: 10.1016/j.tig.2015.10.002

Ancient genomes reveal social and genetic structure of Late Neolithic Switzerland
journal, April 2020

  • Furtwängler, Anja; Rohrlach, A. B.; Lamnidis, Thiseas C.
  • Nature Communications, Vol. 11, Issue 1
  • DOI: 10.1038/s41467-020-15560-x

Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells
journal, May 2021


New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
text, January 2010

  • Guindon, Stéphane; Dufayard, Jean-François; Lefort, Vincent
  • Oxford University Press
  • DOI: 10.5167/uzh-155669

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
text, January 2010


The Genomic Signature of Crop-Wild Introgression in Maize
text, January 2012


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Association between blooming time and climatic adaptation in Prunus mume
journal, December 2019

  • Shi, Ting; Luo, Wenjie; Li, Hantao
  • Ecology and Evolution, Vol. 10, Issue 1
  • DOI: 10.1002/ece3.5894

Towards an Effective and Efficient Management of Genome Data: An Information Systems Engineering Perspective
book, May 2019

  • García S., Alberto; Reyes Román, José Fabián; Casamayor, Juan Carlos
  • Information Systems Engineering in Responsible Information Systems: CAiSE Forum 2019, Rome, Italy, June 3–7, 2019, Proceedings, p. 99-110
  • DOI: 10.1007/978-3-030-21297-1_9

New Citrus chloroplast haplotypes revealed by molecular markers using Algerian and Spanish accessions
journal, September 2018

  • Maddi, Taklit; Pérez-Román, Estela; Maiza-Benabdesselam, Fadila
  • Genetic Resources and Crop Evolution, Vol. 65, Issue 8
  • DOI: 10.1007/s10722-018-0685-7

Genome sequences of horticultural plants: past, present, and future
journal, October 2019


CitGVD: a comprehensive database of citrus genomic variations
journal, February 2020


The structure and function of the global citrus rhizosphere microbiome
journal, November 2018


Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex
journal, February 2019


Subfunctionalization of the Ruby2–Ruby1 gene cluster during the domestication of citrus
journal, October 2018


Evolution of self-compatibility by a mutant Sm-RNase in citrus
journal, February 2020


Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L.
journal, October 2018


Differential Impacts of Citrus Thrips Across Sweet Orange and Mandarin Species
journal, July 2019

  • Mueller, Tobias G.; Kahl, Hanna M.; Cass, Bodil N.
  • Journal of Economic Entomology, Vol. 112, Issue 6
  • DOI: 10.1093/jee/toz178

Resistance of Fruits From a Mandarin Cultivar to Feeding by Fork-Tailed Bush Katydids
journal, October 2019

  • Cass, Bodil N.; Grafton-Cardwell, Elizabeth E.; Rosenheim, Jay A.
  • Journal of Economic Entomology, Vol. 112, Issue 6
  • DOI: 10.1093/jee/toz241

Recombination and Large Structural Variations Shape Interspecific Edible Bananas Genomes
journal, November 2018

  • Baurens, Franc-Christophe; Martin, Guillaume; Hervouet, Catherine
  • Molecular Biology and Evolution, Vol. 36, Issue 1
  • DOI: 10.1093/molbev/msy199

Phylogenomics Reveals an Ancient Hybrid Origin of the Persian Walnut
journal, June 2019

  • Zhang, Bo-Wen; Xu, Lin-Lin; Li, Nan
  • Molecular Biology and Evolution, Vol. 36, Issue 11
  • DOI: 10.1093/molbev/msz112

Hesperidin supplementation has no effect on blood glucose control: A systematic review and meta‐analysis of randomized controlled clinical trials
journal, December 2019

  • Shams‐Rad, Shamim; Mohammadi, Mohammad; Ramezani‐Jolfaie, Nahid
  • British Journal of Clinical Pharmacology, Vol. 86, Issue 1
  • DOI: 10.1111/bcp.14120

The complex evolutionary history of apricots: Species divergence, gene flow and multiple domestication events
journal, November 2019

  • Liu, Shuo; Cornille, Amandine; Decroocq, Stéphane
  • Molecular Ecology, Vol. 28, Issue 24
  • DOI: 10.1111/mec.15296

Phyllosticta citricarpa and sister species of global importance to Citrus
journal, September 2019

  • Guarnaccia, Vladimiro; Gehrmann, Thies; Silva‐Junior, Geraldo J.
  • Molecular Plant Pathology, Vol. 20, Issue 12
  • DOI: 10.1111/mpp.12861

Genome sequencing and CRISPR /Cas9 gene editing of an early flowering Mini‐Citrus ( Fortunella hindsii )
journal, May 2019

  • Zhu, Chenqiao; Zheng, Xiongjie; Huang, Yue
  • Plant Biotechnology Journal, Vol. 17, Issue 11
  • DOI: 10.1111/pbi.13132

A high-throughput SNP discovery strategy for RNA-seq data
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journal, September 2019

  • Patané, José S. L.; Martins, Joaquim; Rangel, Luiz Thiberio
  • BMC Genomics, Vol. 20, Issue 1
  • DOI: 10.1186/s12864-019-6007-4

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Simulation-Based Evaluation of Three Methods for Local Ancestry Deconvolution of Non-model Crop Species Genomes
journal, December 2019

  • Cottin, Aurélien; Penaud, Benjamin; Glaszmann, Jean-Christophe
  • G3: Genes|Genomes|Genetics, Vol. 10, Issue 2
  • DOI: 10.1534/g3.119.400873

Volatile Compounds in Citrus Essential Oils: A Comprehensive Review
journal, February 2019

  • González-Mas, M. Carmen; Rambla, José L.; López-Gresa, M. Pilar
  • Frontiers in Plant Science, Vol. 10
  • DOI: 10.3389/fpls.2019.00012

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journal, April 2019

  • De Ollas, Carlos; Morillón, Raphaël; Fotopoulos, Vasileios
  • Frontiers in Plant Science, Vol. 10
  • DOI: 10.3389/fpls.2019.00427

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  • Sadka, Avi; Shlizerman, Lyudmila; Kamara, Itzhak
  • Frontiers in Plant Science, Vol. 10
  • DOI: 10.3389/fpls.2019.01167

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journal, July 2019

  • Kimball, Rebecca T.; Oliveros, Carl H.; Wang, Ning
  • Diversity, Vol. 11, Issue 7
  • DOI: 10.3390/d11070109

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  • Damasco, Gabriel; Shivakumar, Vikram S.; Misciewicz, Tracy M.
  • Genes, Vol. 10, Issue 5
  • DOI: 10.3390/genes10050392

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  • Nadi, Roya; Golein, Behrouz; Gómez-Cadenas, Aurelio
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  • DOI: 10.1093/jxb/erz506

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  • DOI: 10.5194/we-21-15-2021