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Title: Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging

Abstract

5BMF is a new fluorescent mitochondria-accumulating delocalized lipophilic cations [DLC] that boasts significantly increased anti-cancer effects and low toxicity in comparison to previous DLCs, addressing current hurdles in DLC clinical translation.

Authors:
 [1];  [2];  [3];  [3];  [3];  [3];  [3];  [3];  [3];  [4];  [4]; ORCiD logo [3]
  1. Department of Radiology, The First Hospital of Jilin University, Changchun, China, Center for Molecular Imaging Research
  2. Department of Radiology, The First Hospital of Jilin University, Changchun, China, Molecular Imaging Program at Stanford (MIPS)
  3. Molecular Imaging Program at Stanford (MIPS), Bio-X Program, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University
  4. Department of Radiology, The First Hospital of Jilin University, Changchun, China
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1542520
Grant/Contract Number:  
SC0008397
Resource Type:
Published Article
Journal Name:
Chemical Science
Additional Journal Information:
Journal Name: Chemical Science Journal Volume: 10 Journal Issue: 34; Journal ID: ISSN 2041-6520
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Chen, Hao, Wang, Jing, Feng, Xin, Zhu, Mark, Hoffmann, Simon, Hsu, Alex, Qian, Kun, Huang, Daijuan, Zhao, Feng, Liu, Wei, Zhang, Huimao, and Cheng, Zhen. Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging. United Kingdom: N. p., 2019. Web. doi:10.1039/C9SC01410A.
Chen, Hao, Wang, Jing, Feng, Xin, Zhu, Mark, Hoffmann, Simon, Hsu, Alex, Qian, Kun, Huang, Daijuan, Zhao, Feng, Liu, Wei, Zhang, Huimao, & Cheng, Zhen. Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging. United Kingdom. doi:10.1039/C9SC01410A.
Chen, Hao, Wang, Jing, Feng, Xin, Zhu, Mark, Hoffmann, Simon, Hsu, Alex, Qian, Kun, Huang, Daijuan, Zhao, Feng, Liu, Wei, Zhang, Huimao, and Cheng, Zhen. Wed . "Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging". United Kingdom. doi:10.1039/C9SC01410A.
@article{osti_1542520,
title = {Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging},
author = {Chen, Hao and Wang, Jing and Feng, Xin and Zhu, Mark and Hoffmann, Simon and Hsu, Alex and Qian, Kun and Huang, Daijuan and Zhao, Feng and Liu, Wei and Zhang, Huimao and Cheng, Zhen},
abstractNote = {5BMF is a new fluorescent mitochondria-accumulating delocalized lipophilic cations [DLC] that boasts significantly increased anti-cancer effects and low toxicity in comparison to previous DLCs, addressing current hurdles in DLC clinical translation.},
doi = {10.1039/C9SC01410A},
journal = {Chemical Science},
number = 34,
volume = 10,
place = {United Kingdom},
year = {2019},
month = {8}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1039/C9SC01410A

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