Cytokinin Transporters: Multisite Players in Cytokinin Homeostasis and Signal Distribution

Liu, Chang -Jun; Zhao, Yunjun; Zhang, Kewei

doi:10.3389/fpls.2019.00693

Title: Cytokinin Transporters: Multisite Players in Cytokinin Homeostasis and Signal Distribution

Journal Article · 31 May 2019 · Frontiers in Plant Science

DOI: https://doi.org/10.3389/fpls.2019.00693 · OSTI ID:1542279

Liu, Chang -Jun ^[1]; Zhao, Yunjun ^[1]; Zhang, Kewei ^[2]

Brookhaven National Lab. (BNL), Upton, NY (United States)
Zhejiang Normal Univ., Jinhua (China)

Here, cytokinins are a group of mobile adenine derivatives that act as chemical signals regulating a variety of biological processes implicated in plant development and stress responses. Their synthesis, homeostasis, and signaling perception evoke complicated intracellular traffic, intercellular movement, and in short- and long-distance translocation. Over nearly two decades, subsets of membrane transporters have been recognized and implicated in the transport of cytokinins as well as the related adenylates. In this review, we aim to recapitulate the key progresses in the exploration of the transporter proteins involved in cytokinin traffic and translocation, discuss their functional implications in the cytokinin-mediated paracrine and long-distance communication, and highlight some knowledge gaps and open issues toward comprehensively understanding the molecular mechanism of membrane transporters in controlling spatiotemporal distribution of cytokinin species.

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Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)

Grant/Contract Number:: SC0012704

OSTI ID:: 1542279

Report Number(s):: BNL--211842-2019-JAAM

Journal Information:: Frontiers in Plant Science, Journal Name: Frontiers in Plant Science Vol. 10; ISSN 1664-462X

Publisher:: Frontiers Research FoundationCopyright Statement

Country of Publication:: United States

Language:: English

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AtIPT3 is a Key Determinant of Nitrate-Dependent Cytokinin Biosynthesis in Arabidopsis Takei, Kentaro; Ueda, Nanae; Aoki, Koh Plant and Cell Physiology, Vol. 45, Issue 8 https://doi.org/10.1093/pcp/pch119	journal	August 2004
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Functional Characterization and Expression Analysis of a Gene, OsENT2 , Encoding an Equilibrative Nucleoside Transporter in Rice Suggest a Function in Cytokinin Transport Hirose, Naoya; Makita, Nobue; Yamaya, Tomoyuki Plant Physiology, Vol. 138, Issue 1 https://doi.org/10.1104/pp.105.060137	journal	April 2005
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Proteome Analysis in Arabidopsis Reveals Shoot- and Root-Specific Targets of Cytokinin Action and Differential Regulation of Hormonal Homeostasis Žd'árská, Markéta; Zatloukalová, Pavlína; Benítez, Mariana Plant Physiology, Vol. 161, Issue 2 https://doi.org/10.1104/pp.112.202853	journal	December 2012
A Robust and Sensitive Synthetic Sensor to Monitor the Transcriptional Output of the Cytokinin Signaling Network in Planta Zürcher, Evelyne; Tavor-Deslex, Deborah; Lituiev, Dmytro Plant Physiology, Vol. 161, Issue 3 https://doi.org/10.1104/pp.112.211763	journal	January 2013
Structure and Function of Nucleoside Hydrolases from Physcomitrella patens and Maize Catalyzing the Hydrolysis of Purine, Pyrimidine, and Cytokinin Ribosides Kopecna, M.; Blaschke, H.; Kopecny, D. PLANT PHYSIOLOGY, Vol. 163, Issue 4 https://doi.org/10.1104/pp.113.228775	journal	October 2013
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