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Title: Biosynthesis, regulation, and engineering of microbially produced branched biofuels

Abstract

The steadily increasing demand on transportation fuels calls for renewable fuel replacements. This has attracted a growing amount of research to develop advanced biofuels that have similar physical, chemical, and combustion properties with petroleum-derived fossil fuels. Early generations of biofuels, such as ethanol, butanol, and straight-chain fatty acid-derived esters or hydrocarbons suffer from various undesirable properties and can only be blended in limited amounts. Recent research has shifted to the production of branched-chain biofuels that, compared to straight-chain fuels, have higher octane values, better cold flow and lower cloud points, making them more suitable for existing engines, particularly for diesel and jet engines. This review focuses on several types of branched-chain biofuels and their immediate precursors, including branched short-chain (C4-C8) and long-chain (C15-C19)-alcohols, alkanes, and esters. We discuss their biosynthesis, regulation, and recent efforts in their overproduction by engineered microbes.

Authors:
 [1];  [1];  [1]; ORCiD logo [1]
  1. Washington Univ., St. Louis, MO (United States)
Publication Date:
Research Org.:
Washington Univ., St. Louis, MO (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23). Biological Systems Science Division
OSTI Identifier:
1529120
Grant/Contract Number:  
SC0018324
Resource Type:
Accepted Manuscript
Journal Name:
Biotechnology for Biofuels
Additional Journal Information:
Journal Volume: 12; Journal Issue: 1; Journal ID: ISSN 1754-6834
Publisher:
BioMed Central
Country of Publication:
United States
Language:
English
Subject:
09 BIOMASS FUELS; Advanced biofuels; Branched fuels; Branched fatty acids; Branched alcohols; Cyclopropane fatty acid

Citation Formats

Bai, Wenqin, Geng, Weitao, Wang, Shaojie, and Zhang, Fuzhong. Biosynthesis, regulation, and engineering of microbially produced branched biofuels. United States: N. p., 2019. Web. doi:10.1186/s13068-019-1424-9.
Bai, Wenqin, Geng, Weitao, Wang, Shaojie, & Zhang, Fuzhong. Biosynthesis, regulation, and engineering of microbially produced branched biofuels. United States. doi:10.1186/s13068-019-1424-9.
Bai, Wenqin, Geng, Weitao, Wang, Shaojie, and Zhang, Fuzhong. Sat . "Biosynthesis, regulation, and engineering of microbially produced branched biofuels". United States. doi:10.1186/s13068-019-1424-9. https://www.osti.gov/servlets/purl/1529120.
@article{osti_1529120,
title = {Biosynthesis, regulation, and engineering of microbially produced branched biofuels},
author = {Bai, Wenqin and Geng, Weitao and Wang, Shaojie and Zhang, Fuzhong},
abstractNote = {The steadily increasing demand on transportation fuels calls for renewable fuel replacements. This has attracted a growing amount of research to develop advanced biofuels that have similar physical, chemical, and combustion properties with petroleum-derived fossil fuels. Early generations of biofuels, such as ethanol, butanol, and straight-chain fatty acid-derived esters or hydrocarbons suffer from various undesirable properties and can only be blended in limited amounts. Recent research has shifted to the production of branched-chain biofuels that, compared to straight-chain fuels, have higher octane values, better cold flow and lower cloud points, making them more suitable for existing engines, particularly for diesel and jet engines. This review focuses on several types of branched-chain biofuels and their immediate precursors, including branched short-chain (C4-C8) and long-chain (C15-C19)-alcohols, alkanes, and esters. We discuss their biosynthesis, regulation, and recent efforts in their overproduction by engineered microbes.},
doi = {10.1186/s13068-019-1424-9},
journal = {Biotechnology for Biofuels},
number = 1,
volume = 12,
place = {United States},
year = {2019},
month = {4}
}

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Works referenced in this record:

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