Biosynthesis, regulation, and engineering of microbially produced branched biofuels
Abstract
The steadily increasing demand on transportation fuels calls for renewable fuel replacements. This has attracted a growing amount of research to develop advanced biofuels that have similar physical, chemical, and combustion properties with petroleum-derived fossil fuels. Early generations of biofuels, such as ethanol, butanol, and straight-chain fatty acid-derived esters or hydrocarbons suffer from various undesirable properties and can only be blended in limited amounts. Recent research has shifted to the production of branched-chain biofuels that, compared to straight-chain fuels, have higher octane values, better cold flow and lower cloud points, making them more suitable for existing engines, particularly for diesel and jet engines. This review focuses on several types of branched-chain biofuels and their immediate precursors, including branched short-chain (C4-C8) and long-chain (C15-C19)-alcohols, alkanes, and esters. We discuss their biosynthesis, regulation, and recent efforts in their overproduction by engineered microbes.
- Publication Date:
- Research Org.:
- Washington Univ., St. Louis, MO (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division; National Science Foundation (NSF)
- OSTI Identifier:
- 1618763
- Alternate Identifier(s):
- OSTI ID: 1529120; OSTI ID: 1593362
- Grant/Contract Number:
- DESC0018324; SC0018324
- Resource Type:
- Published Article
- Journal Name:
- Biotechnology for Biofuels
- Additional Journal Information:
- Journal Name: Biotechnology for Biofuels Journal Volume: 12 Journal Issue: 1; Journal ID: ISSN 1754-6834
- Publisher:
- Springer Science + Business Media
- Country of Publication:
- Netherlands
- Language:
- English
- Subject:
- 09 BIOMASS FUELS; Advanced biofuels; Branched fuels; Branched fatty acids; Branched alcohols; Cyclopropane fatty acid
Citation Formats
Bai, Wenqin, Geng, Weitao, Wang, Shaojie, and Zhang, Fuzhong. Biosynthesis, regulation, and engineering of microbially produced branched biofuels. Netherlands: N. p., 2019.
Web. doi:10.1186/s13068-019-1424-9.
Bai, Wenqin, Geng, Weitao, Wang, Shaojie, & Zhang, Fuzhong. Biosynthesis, regulation, and engineering of microbially produced branched biofuels. Netherlands. https://doi.org/10.1186/s13068-019-1424-9
Bai, Wenqin, Geng, Weitao, Wang, Shaojie, and Zhang, Fuzhong. Sat .
"Biosynthesis, regulation, and engineering of microbially produced branched biofuels". Netherlands. https://doi.org/10.1186/s13068-019-1424-9.
@article{osti_1618763,
title = {Biosynthesis, regulation, and engineering of microbially produced branched biofuels},
author = {Bai, Wenqin and Geng, Weitao and Wang, Shaojie and Zhang, Fuzhong},
abstractNote = {The steadily increasing demand on transportation fuels calls for renewable fuel replacements. This has attracted a growing amount of research to develop advanced biofuels that have similar physical, chemical, and combustion properties with petroleum-derived fossil fuels. Early generations of biofuels, such as ethanol, butanol, and straight-chain fatty acid-derived esters or hydrocarbons suffer from various undesirable properties and can only be blended in limited amounts. Recent research has shifted to the production of branched-chain biofuels that, compared to straight-chain fuels, have higher octane values, better cold flow and lower cloud points, making them more suitable for existing engines, particularly for diesel and jet engines. This review focuses on several types of branched-chain biofuels and their immediate precursors, including branched short-chain (C4-C8) and long-chain (C15-C19)-alcohols, alkanes, and esters. We discuss their biosynthesis, regulation, and recent efforts in their overproduction by engineered microbes.},
doi = {10.1186/s13068-019-1424-9},
journal = {Biotechnology for Biofuels},
number = 1,
volume = 12,
place = {Netherlands},
year = {Sat Apr 13 00:00:00 EDT 2019},
month = {Sat Apr 13 00:00:00 EDT 2019}
}
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1186/s13068-019-1424-9
https://doi.org/10.1186/s13068-019-1424-9
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 17 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
ESR Studies on the Membrane Properties of a Moderately Halophilic Bacterium
journal, October 1980
- Hara, Hisako; Hyono, Atsushi; Kuriyama, Shigeko
- The Journal of Biochemistry, Vol. 88, Issue 5
Coexpressing Escherichia coli Cyclopropane Synthase with Sterculia foetida Lysophosphatidic Acid Acyltransferase Enhances Cyclopropane Fatty Acid Accumulation
journal, November 2013
- Yu, X. -H.; Prakash, R. R.; Sweet, M.
- PLANT PHYSIOLOGY, Vol. 164, Issue 1
Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels
journal, January 2014
- Janßen, Helge; Steinbüchel, Alexander
- Biotechnology for Biofuels, Vol. 7, Issue 1
Production of medium chain length fatty alcohols from glucose in Escherichia coli
journal, November 2013
- Youngquist, J. Tyler; Schumacher, Martin H.; Rose, Joshua P.
- Metabolic Engineering, Vol. 20
Phylogenomic Investigation of Phospholipid Synthesis in Archaea
journal, January 2012
- Lombard, Jonathan; López-García, Purificación; Moreira, David
- Archaea, Vol. 2012
Engineering Microbial Metabolite Dynamics and Heterogeneity
journal, September 2017
- Schmitz, Alexander C.; Hartline, Christopher J.; Zhang, Fuzhong
- Biotechnology Journal, Vol. 12, Issue 10
Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli
journal, May 2011
- Bastian, Sabine; Liu, Xiang; Meyerowitz, Joseph T.
- Metabolic Engineering, Vol. 13, Issue 3, p. 345-352
Role of BkdR, a Transcriptional Activator of the SigL-Dependent Isoleucine and Valine Degradation Pathway inBacillus subtilis
journal, April 1999
- Debarbouille, Michel; Gardan, Rozenn; Arnaud, Maryvonne
- Journal of Bacteriology, Vol. 181, Issue 7
Effect of growth temperature on the long-chain diols and fatty acids of Thermomicrobium roseum.
journal, March 1987
- Pond, J. L.; Langworthy, T. A.
- Journal of Bacteriology, Vol. 169, Issue 3
Metabolic engineering of the pentose phosphate pathway for enhanced limonene production in the cyanobacterium Synechocysti s sp. PCC 6803
journal, December 2017
- Lin, Po-Cheng; Saha, Rajib; Zhang, Fuzhong
- Scientific Reports, Vol. 7, Issue 1
Steps towards ‘drop-in’ biofuels: focusing on metabolic pathways
journal, October 2018
- Jiang, Wen; Gu, Pengfei; Zhang, Fuzhong
- Current Opinion in Biotechnology, Vol. 53
Production of anteiso-branched fatty acids in Escherichia coli; next generation biofuels with improved cold-flow properties
journal, November 2014
- Haushalter, Robert W.; Kim, Woncheol; Chavkin, Ted A.
- Metabolic Engineering, Vol. 26
Production of 2-methyl-1-butanol and 3-methyl-1-butanol in engineered Corynebacterium glutamicum
journal, November 2016
- Vogt, Michael; Brüsseler, Christian; Ooyen, Jan van
- Metabolic Engineering, Vol. 38
Physiological Characterization of the ARO10-Dependent, Broad-Substrate-Specificity 2-Oxo Acid Decarboxylase Activity of Saccharomyces cerevisiae
journal, June 2005
- Vuralhan, Z.; Luttik, M. A. H.; Tai, S. L.
- Applied and Environmental Microbiology, Vol. 71, Issue 6
Expression of Genes for a Flavin Adenine Dinucleotide-Binding Oxidoreductase and a Methyltransferase from Mycobacterium chlorophenolicum Is Necessary for Biosynthesis of 10-Methyl Stearic Acid from Oleic Acid in Escherichia coli
journal, October 2017
- Machida, Shuntaro; Bakku, Ranjith K.; Suzuki, Iwane
- Frontiers in Microbiology, Vol. 8
Binding of L-branched-chain amino acids causes a conformational change in BkdR.
journal, January 1997
- Madhusudhan, K. T.; Huang, N.; Braswell, E. H.
- Journal of Bacteriology, Vol. 179, Issue 1
Genetic engineering to enhance the Ehrlich pathway and alter carbon flux for increased isobutanol production from glucose by Saccharomyces cerevisiae
journal, May 2012
- Kondo, Takashi; Tezuka, Hironori; Ishii, Jun
- Journal of Biotechnology, Vol. 159, Issue 1-2
FabH selectivity for anteiso branched-chain fatty acid precursors in low-temperature adaptation in Listeria monocytogenes
journal, December 2009
- Singh, Atul K.; Zhang, Yong-Mei; Zhu, Kun
- FEMS Microbiology Letters, Vol. 301, Issue 2
Biochemical characterization of an S-adenosyl-l-methionine-dependent methyltransferase (Rv0469) of Mycobacterium tuberculosis
journal, July 2013
- Meena, Laxman S.; Chopra, Puneet; Vishwakarma, Ram A.
- Biological Chemistry, Vol. 394, Issue 7
The Envelope of Mycobacteria
journal, June 1995
- Brennan, Patrick J.; Nikaido, Hiroshi
- Annual Review of Biochemistry, Vol. 64, Issue 1
Metabolic engineering of microbial pathways for advanced biofuels production
journal, December 2011
- Zhang, Fuzhong; Rodriguez, Sarah; Keasling, Jay D.
- Current Opinion in Biotechnology, Vol. 22, Issue 6
Modular pathway engineering for the microbial production of branched-chain fatty alcohols
journal, October 2017
- Jiang, Wen; Qiao, James B.; Bentley, Gayle J.
- Biotechnology for Biofuels, Vol. 10, Issue 1
Engineering Bacillus subtilis for isobutanol production by heterologous Ehrlich pathway construction and the biosynthetic 2-ketoisovalerate precursor pathway overexpression
journal, April 2011
- Li, Shanshan; Wen, Jianping; Jia, Xiaoqiang
- Applied Microbiology and Biotechnology, Vol. 91, Issue 3
Activation of the Bacillus subtilis global regulator CodY by direct interaction with branched-chain amino acids: CodY activation by amino acids
journal, June 2004
- Shivers, Robert P.; Sonenshein, Abraham L.
- Molecular Microbiology, Vol. 53, Issue 2
An Investigation of the Metabolism of Valine to Isobutyl Alcohol in Saccharomyces cerevisiae
journal, October 1998
- Dickinson, J. Richard; Harrison, Scott J.; Hewlins, Michael J. E.
- Journal of Biological Chemistry, Vol. 273, Issue 40, p. 25751-25756
Improving biodiesel fuel properties by modifying fatty ester composition
journal, January 2009
- Knothe, Gerhard
- Energy & Environmental Science, Vol. 2, Issue 7
Engineering Escherichia coli to produce branched-chain fatty acids in high percentages
journal, November 2016
- Bentley, Gayle J.; Jiang, Wen; Guamán, Linda P.
- Metabolic Engineering, Vol. 38
Strain optimization for efficient isobutanol production using Corynebacterium glutamicum under oxygen deprivation : Extractive Isobutanol Production by
journal, June 2013
- Yamamoto, Shogo; Suda, Masako; Niimi, Satoko
- Biotechnology and Bioengineering, Vol. 110, Issue 11
A new physiological role for Pdr12p in Saccharomyces cerevisiae : export of aromatic and branched-chain organic acids produced in amino acid catabolism
journal, September 2006
- Hazelwood, Lucie A.; Tai, Siew Leng; Boer, Viktor M.
- FEMS Yeast Research, Vol. 6, Issue 6
Expression and characterization of Rv0447c product, potentially the methyltransferase involved in tuberculostearic acid biosynthesis in Mycobacterium tuberculosis : Biosynthesis of Tuberculostearic Acid
journal, July 2013
- Meena, Laxman S.; Kolattukudy, Pappachan E.
- Biotechnology and Applied Biochemistry, Vol. 60, Issue 4
Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels
journal, July 2006
- Hill, J.; Nelson, E.; Tilman, D.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 30
Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli
journal, April 2013
- Howard, T. P.; Middelhaufe, S.; Moore, K.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 19
3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation
journal, January 2010
- Connor, Michael R.; Cann, Anthony F.; Liao, James C.
- Applied Microbiology and Biotechnology, Vol. 86, Issue 4
Carbocyclic fatty acids in plants: Biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of Sterculia foetida
journal, May 2002
- Bao, X.; Katz, S.; Pollard, M.
- Proceedings of the National Academy of Sciences, Vol. 99, Issue 10
Iso- and anteiso-fatty acids in bacteria: biosynthesis, function, and taxonomic significance.
journal, January 1991
- Kaneda, T.
- Microbiological Reviews, Vol. 55, Issue 2
Current knowledge on isobutanol production with Escherichia coli , Bacillus subtilis and Corynebacterium glutamicum
journal, November 2011
- Blombach, Bastian; Eikmanns, Bernhard J.
- Bioengineered Bugs, Vol. 2, Issue 6
The formation of cyclopropane fatty acids in Salmonella enterica serovar Typhimurium
journal, January 2005
- Kim, B. H.
- Microbiology, Vol. 151, Issue 1
Rewriting yeast central carbon metabolism for industrial isoprenoid production
journal, September 2016
- Meadows, Adam L.; Hawkins, Kristy M.; Tsegaye, Yoseph
- Nature, Vol. 537, Issue 7622
Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization
journal, August 2017
- Meadows, Corey W.; Kang, Aram; Lee, Taek S.
- Biotechnology Journal, Vol. 13, Issue 1
Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432
journal, June 2001
- Alvarez, Héctor M.; Souto, Maria F.; Viale, Alberto
- FEMS Microbiology Letters, Vol. 200, Issue 2
Dynamic metabolic control: towards precision engineering of metabolism
journal, January 2018
- Liu, Di; Mannan, Ahmad A.; Han, Yichao
- Journal of Industrial Microbiology & Biotechnology, Vol. 45, Issue 7
The Ehrlich Pathway for Fusel Alcohol Production: a Century of Research on Saccharomyces cerevisiae Metabolism
journal, February 2008
- Hazelwood, L. A.; Daran, J. -M.; van Maris, A. J. A.
- Applied and Environmental Microbiology, Vol. 74, Issue 8
Membrane topology of Salmonella invasion protein SipB confers osmotolerance
journal, October 2012
- Asakura, Hiroshi; Ekawa, Tomoya; Sugimoto, Naoki
- Biochemical and Biophysical Research Communications, Vol. 426, Issue 4
New branched-chain fatty acids from the senegalese gorgonianLeptogorgia piccola (white and yellow morphs)
journal, May 1995
- Mirallès, Joseph; Barnathan, Gilles; Galonnier, Renée
- Lipids, Vol. 30, Issue 5
Cyclopropane fatty acids improve Escherichia coli survival in acidified minimal media by reducing membrane permeability to H+ and enhanced ability to extrude H+
journal, July 2008
- Shabala, Lana; Ross, Tom
- Research in Microbiology, Vol. 159, Issue 6
Metabolically engineered Saccharomyces cerevisiae for branched-chain ester productions
journal, December 2016
- Yuan, Jifeng; Mishra, Pranjul; Ching, Chi Bun
- Journal of Biotechnology, Vol. 239
Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production
journal, April 2018
- Tan, Zaigao; Yoon, Jong Moon; Chowdhury, Anupam
- Biotechnology for Biofuels, Vol. 11, Issue 1
High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal
journal, March 2011
- Baez, Antonino; Cho, Kwang-Myung; Liao, James C.
- Applied Microbiology and Biotechnology, Vol. 90, Issue 5
Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatidylinositol dimannosides
journal, March 2014
- Bansal-Mutalik, Ritu; Nikaido, Hiroshi
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 13
Expanding metabolism for biosynthesis of nonnatural alcohols
journal, December 2008
- Zhang, K.; Sawaya, M. R.; Eisenberg, D. S.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 52
beta -Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is a Determining Factor in Branched-Chain Fatty Acid Biosynthesis
journal, January 2000
- Choi, K. -H.; Heath, R. J.; Rock, C. O.
- Journal of Bacteriology, Vol. 182, Issue 2
Bacillus subtilis ilvB operon: an intersection of global regulons : CcpA and CodY control
journal, April 2005
- Shivers, Robert P.; Sonenshein, Abraham L.
- Molecular Microbiology, Vol. 56, Issue 6
MS/MS Approach for Characterization of the Fatty Acid Distribution on Mycobacterial Phosphatidyl- myo -inositol Mannosides
journal, December 2006
- Gilleron, Martine; Lindner, Buko; Puzo, Germain
- Analytical Chemistry, Vol. 78, Issue 24
A Comprehensive Evaluation of the Melting Points of Fatty Acids and Esters Determined by Differential Scanning Calorimetry
journal, June 2009
- Knothe, Gerhard; Dunn, Robert O.
- Journal of the American Oil Chemists' Society, Vol. 86, Issue 9
Metabolic engineering of Escherichia coli for production of fatty acid short-chain esters through combination of the fatty acid and 2-keto acid pathways
journal, March 2014
- Guo, Daoyi; Zhu, Jing; Deng, Zixin
- Metabolic Engineering, Vol. 22
Cold induction of the Bacillus subtilis bkd operon is mediated by increased mRNA stability
journal, July 2004
- Nickel, M.; Homuth, G.; B�hnisch, C.
- Molecular Genetics and Genomics, Vol. 272, Issue 1
Anaerobic production of medium-chain fatty alcohols via a β-reduction pathway
journal, July 2018
- Mehrer, Christopher R.; Incha, Matthew R.; Politz, Mark C.
- Metabolic Engineering, Vol. 48
Interplay of Aro80 and GATA activators in regulation of genes for catabolism of aromatic amino acids in Saccharomyces cerevisiae : Regulation of genes for aromatic amino acids catabolism
journal, May 2013
- Lee, Kyusung; Hahn, Ji-Sook
- Molecular Microbiology, Vol. 88, Issue 6
Lipomannan and Lipoarabinomannan from a Clinical Isolate of Mycobacterium kansasii : NOVEL STRUCTURAL FEATURES AND APOPTOSIS-INDUCING PROPERTIES
journal, June 2003
- Guérardel, Yann; Maes, Emmanuel; Briken, Volker
- Journal of Biological Chemistry, Vol. 278, Issue 38
Cyclopropane ring formation in membrane lipids of bacteria.
journal, January 1997
- Grogan, D. W.; Cronan, J. E.
- Microbiology and molecular biology reviews : MMBR, Vol. 61, Issue 4
Practical Strategies for Discovering Regulatory DNA Sequence Motifs
journal, January 2006
- MacIsaac, Kenzie D.; Fraenkel, Ernest
- PLoS Computational Biology, Vol. 2, Issue 4
Metabolic Feedback Circuits Provide Rapid Control of Metabolite Dynamics
journal, January 2018
- Liu, Di; Zhang, Fuzhong
- ACS Synthetic Biology, Vol. 7, Issue 2
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
journal, January 2008
- Atsumi, Shota; Hanai, Taizo; Liao, James C.
- Nature, Vol. 451, Issue 7174, p. 86-89
Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property
journal, June 2015
- Tao, Hui; Guo, Daoyi; Zhang, Yuchen
- Biotechnology for Biofuels, Vol. 8, Issue 1
Applications and advances of metabolite biosensors for metabolic engineering
journal, September 2015
- Liu, Di; Evans, Trent; Zhang, Fuzhong
- Metabolic Engineering, Vol. 31
Cyclopropane fatty acids are involved in organic solvent tolerance but not in acid stress resistance in Pseudomonas putida DOT-T1E
journal, March 2009
- Pini, Cecilia-Vanesa; Bernal, Patricia; Godoy, Patricia
- Microbial Biotechnology, Vol. 2, Issue 2
Activation of Aro80 transcription factor by heat-induced aromatic amino acid influx in Saccharomyces cerevisiae
journal, August 2013
- Lee, Kyusung; Sung, Changmin; Kim, Byung-Gee
- Biochemical and Biophysical Research Communications, Vol. 438, Issue 1
Integrated Electromicrobial Conversion of CO2 to Higher Alcohols
journal, March 2012
- Li, H.; Opgenorth, P. H.; Wernick, D. G.
- Science, Vol. 335, Issue 6076, p. 1596-1596
Expanding ester biosynthesis in Escherichia coli
journal, March 2014
- Rodriguez, Gabriel M.; Tashiro, Yohei; Atsumi, Shota
- Nature Chemical Biology, Vol. 10, Issue 4
Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis
journal, March 2016
- Xiao, Yi; Bowen, Christopher H.; Liu, Di
- Nature Chemical Biology, Vol. 12, Issue 5
Biosynthesis of Branched-Chain Fatty Acids: iv. Factors Affecting Relative Abundance of Fatty Acids Produced by Bacillus Subtilis
journal, June 1966
- Kaneda, Toshi
- Canadian Journal of Microbiology, Vol. 12, Issue 3
Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance
journal, January 2013
- Matsuda, Fumio; Ishii, Jun; Kondo, Takashi
- Microbial Cell Factories, Vol. 12, Issue 1
Fatty Acid Distribution in Bacterial Phospholipids. The Specificity of the Cyclopropane Synthetase Reaction *
journal, September 1964
- Hildebrand, John G.; Law, John H.
- Biochemistry, Vol. 3, Issue 9
Metabolically engineered Saccharomyces cerevisiae for enhanced isoamyl alcohol production
journal, November 2016
- Yuan, Jifeng; Chen, Xue; Mishra, Pranjul
- Applied Microbiology and Biotechnology, Vol. 101, Issue 1
Metabolic engineering of Saccharomyces cerevisiae for the production of isobutanol and 3-methyl-1-butanol
journal, October 2014
- Park, Seong-Hee; Kim, Sujin; Hahn, Ji-Sook
- Applied Microbiology and Biotechnology, Vol. 98, Issue 21
Enhanced production of branched-chain fatty acids by replacing β-ketoacyl-(acyl-carrier-protein) synthase III (FabH): Enhanced Production of Branched-Chain Fatty Acids
journal, April 2015
- Jiang, Wen; Jiang, Yanfang; Bentley, Gayle J.
- Biotechnology and Bioengineering, Vol. 112, Issue 8
Modifications in membrane fatty acid composition of Salmonella typhimurium in response to growth conditions and their effect on heat resistance
journal, April 2008
- Álvarez-Ordóñez, Avelino; Fernández, Ana; López, Mercedes
- International Journal of Food Microbiology, Vol. 123, Issue 3
Membrane cyclopropane fatty acid content is a major factor in acid resistance of Escherichia coli
journal, July 1999
- Chang, Ying-Ying; Cronan, John E.
- Molecular Microbiology, Vol. 33, Issue 2
Comprehensive characterization of toxicity of fermentative metabolites on microbial growth
journal, November 2017
- Wilbanks, Brandon; Trinh, Cong T.
- Biotechnology for Biofuels, Vol. 10, Issue 1
Construction of a cyanobacterium synthesizing cyclopropane fatty acids
journal, September 2016
- Machida, Shuntaro; Shiraiwa, Yoshihiro; Suzuki, Iwane
- Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1861, Issue 9
Production of 2-methyl-1-butanol in engineered Escherichia coli
journal, August 2008
- Cann, Anthony F.; Liao, James C.
- Applied Microbiology and Biotechnology, Vol. 81, Issue 1
A Novel Mycolic Acid Cyclopropane Synthetase Is Required for Cording, Persistence, and Virulence of Mycobacterium tuberculosis
journal, April 2000
- Glickman, Michael S.; Cox, Jeffery S.; Jacobs, William R.
- Molecular Cell, Vol. 5, Issue 4
Bridging the gap between systems biology and synthetic biology
journal, January 2013
- Liu, Di; Hoynes-O’Connor, Allison; Zhang, Fuzhong
- Frontiers in Microbiology, Vol. 4
Effect of Methyl-Branched Fatty Acids on the Structure of Lipid Bilayers
journal, November 2014
- Poger, David; Caron, Bertrand; Mark, Alan E.
- The Journal of Physical Chemistry B, Vol. 118, Issue 48
Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde
journal, November 2009
- Atsumi, Shota; Higashide, Wendy; Liao, James C.
- Nature Biotechnology, Vol. 27, Issue 12, p. 1177-1180
Acid habituation of Escherichia coli and the potential role of cyclopropane fatty acids in low pH tolerance
journal, July 1997
- Brown, Janelle L.; Ross, Thomas; McMeekin, Thomas A.
- International Journal of Food Microbiology, Vol. 37, Issue 2-3
Engineering Brevibacterium flavum for the production of renewable bioenergy: C4-C5 advanced alcohols : Engineering
journal, May 2017
- Su, HaiFeng; Lin, JiaFu; Wang, YuanHong
- Biotechnology and Bioengineering, Vol. 114, Issue 9
ESR Studies on the Membrane Properties of a Moderately Halophilic Bacterium
journal, October 1980
- Hyono, Atsushi; Kuriyama, Shigeko; Hara, Hisako
- The Journal of Biochemistry, Vol. 88, Issue 5
Works referencing / citing this record:
A novel C-terminal degron identified in bacterial aldehyde decarbonylases using directed evolution
journal, June 2020
- Liu, Yilan; Chen, Jinjin; Khusnutdinova, Anna N.
- Biotechnology for Biofuels, Vol. 13, Issue 1
Metabolic engineering of Zymomonas mobilis for anaerobic isobutanol production
journal, January 2020
- Qiu, Mengyue; Shen, Wei; Yan, Xiongyin
- Biotechnology for Biofuels, Vol. 13, Issue 1