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Title: Iron detection and remediation with a functionalized porous polymer applied to environmental water samples

Abstract

Iron is one of the most abundant elements in the environment and in the human body. As an essential nutrient, iron homeostasis is tightly regulated, and iron dysregulation is implicated in numerous pathologies, including neuro-degenerative diseases, atherosclerosis, and diabetes. Endogenous iron pool concentrations are directly linked to iron ion uptake from environmental sources such as drinking water, providing motivation for developing new technologies for assessing iron(II) and iron(III) levels in water. However, conventional methods for measuring aqueous iron pools remain laborious and costly and often require sophisticated equipment and/or additional processing steps to remove the iron ions from the original environmental source. We now report a simplified and accurate chemical platform for capturing and quantifying the iron present in aqueous samples through use of a post-synthetically modified porous aromatic framework (PAF). The ether/thioether-functionalized network polymer, PAF-1–ET, exhibits high selectivity for the uptake of iron(II) and iron(III) over other physiologically and environmentally relevant metal ions. Mössbauer spectroscopy, XANES, and EXAFS measurements provide evidence to support iron(III) coordination to oxygen-based ligands within the material. The polymer is further successfully employed to adsorb and remove iron ions from groundwater, including field sources in West Bengal, India. Combined with an 8-hydroxyquinoline colorimetric indicator, PAF-1–ETmore » enables the simple and direct determination of the iron(II) and iron(III) ion concentrations in these samples, providing a starting point for the design and use of molecularly-functionalized porous materials for potential dual detection and remediation applications.« less

Authors:
ORCiD logo [1]; ORCiD logo [2]; ORCiD logo [1];  [1];  [3];  [4]; ORCiD logo [2];  [1];  [4]; ORCiD logo [1]; ORCiD logo [5];  [4];  [3]; ORCiD logo [6]; ORCiD logo [6]; ORCiD logo [7]; ORCiD logo [8]
  1. Department of Chemistry, University of California, Berkeley, USA
  2. Department of Chemical and Biomolecular Engineering, University of California, Berkeley, USA
  3. Department of Civil and Environmental Engineering, University of California, Berkeley, USA
  4. Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, USA
  5. Department of Chemical and Biomolecular Engineering, University of California, Berkeley, USA, Materials Sciences Division
  6. Department of Chemistry, Missouri University of Science and Technology, University of Missouri, Rolla, USA
  7. Department of Chemistry, University of California, Berkeley, USA, Department of Chemical and Biomolecular Engineering
  8. Department of Chemistry, University of California, Berkeley, USA, Department of Molecular and Cell Biology
Publication Date:
Research Org.:
Energy Frontier Research Centers (EFRC) (United States). Center for Gas Separations Relevant to Clean Energy Technologies (CGS); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1524484
Alternate Identifier(s):
OSTI ID: 1559810
Grant/Contract Number:  
AC02-05CH11231; SC0001015
Resource Type:
Published Article
Journal Name:
Chemical Science
Additional Journal Information:
Journal Name: Chemical Science Journal Volume: 10 Journal Issue: 27; Journal ID: ISSN 2041-6520
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Lee, Sumin, Uliana, Adam, Taylor, Mercedes K., Chakarawet, Khetpakorn, Bandaru, Siva Rama Satyam, Gul, Sheraz, Xu, Jun, Ackerman, Cheri M., Chatterjee, Ruchira, Furukawa, Hiroyasu, Reimer, Jeffrey A., Yano, Junko, Gadgil, Ashok, Long, Gary J., Grandjean, Fernande, Long, Jeffrey R., and Chang, Christopher J. Iron detection and remediation with a functionalized porous polymer applied to environmental water samples. United Kingdom: N. p., 2019. Web. https://doi.org/10.1039/C9SC01441A.
Lee, Sumin, Uliana, Adam, Taylor, Mercedes K., Chakarawet, Khetpakorn, Bandaru, Siva Rama Satyam, Gul, Sheraz, Xu, Jun, Ackerman, Cheri M., Chatterjee, Ruchira, Furukawa, Hiroyasu, Reimer, Jeffrey A., Yano, Junko, Gadgil, Ashok, Long, Gary J., Grandjean, Fernande, Long, Jeffrey R., & Chang, Christopher J. Iron detection and remediation with a functionalized porous polymer applied to environmental water samples. United Kingdom. https://doi.org/10.1039/C9SC01441A
Lee, Sumin, Uliana, Adam, Taylor, Mercedes K., Chakarawet, Khetpakorn, Bandaru, Siva Rama Satyam, Gul, Sheraz, Xu, Jun, Ackerman, Cheri M., Chatterjee, Ruchira, Furukawa, Hiroyasu, Reimer, Jeffrey A., Yano, Junko, Gadgil, Ashok, Long, Gary J., Grandjean, Fernande, Long, Jeffrey R., and Chang, Christopher J. Wed . "Iron detection and remediation with a functionalized porous polymer applied to environmental water samples". United Kingdom. https://doi.org/10.1039/C9SC01441A.
@article{osti_1524484,
title = {Iron detection and remediation with a functionalized porous polymer applied to environmental water samples},
author = {Lee, Sumin and Uliana, Adam and Taylor, Mercedes K. and Chakarawet, Khetpakorn and Bandaru, Siva Rama Satyam and Gul, Sheraz and Xu, Jun and Ackerman, Cheri M. and Chatterjee, Ruchira and Furukawa, Hiroyasu and Reimer, Jeffrey A. and Yano, Junko and Gadgil, Ashok and Long, Gary J. and Grandjean, Fernande and Long, Jeffrey R. and Chang, Christopher J.},
abstractNote = {Iron is one of the most abundant elements in the environment and in the human body. As an essential nutrient, iron homeostasis is tightly regulated, and iron dysregulation is implicated in numerous pathologies, including neuro-degenerative diseases, atherosclerosis, and diabetes. Endogenous iron pool concentrations are directly linked to iron ion uptake from environmental sources such as drinking water, providing motivation for developing new technologies for assessing iron(II) and iron(III) levels in water. However, conventional methods for measuring aqueous iron pools remain laborious and costly and often require sophisticated equipment and/or additional processing steps to remove the iron ions from the original environmental source. We now report a simplified and accurate chemical platform for capturing and quantifying the iron present in aqueous samples through use of a post-synthetically modified porous aromatic framework (PAF). The ether/thioether-functionalized network polymer, PAF-1–ET, exhibits high selectivity for the uptake of iron(II) and iron(III) over other physiologically and environmentally relevant metal ions. Mössbauer spectroscopy, XANES, and EXAFS measurements provide evidence to support iron(III) coordination to oxygen-based ligands within the material. The polymer is further successfully employed to adsorb and remove iron ions from groundwater, including field sources in West Bengal, India. Combined with an 8-hydroxyquinoline colorimetric indicator, PAF-1–ET enables the simple and direct determination of the iron(II) and iron(III) ion concentrations in these samples, providing a starting point for the design and use of molecularly-functionalized porous materials for potential dual detection and remediation applications.},
doi = {10.1039/C9SC01441A},
journal = {Chemical Science},
number = 27,
volume = 10,
place = {United Kingdom},
year = {2019},
month = {7}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1039/C9SC01441A

Citation Metrics:
Cited by: 4 works
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Works referenced in this record:

ATHENA , ARTEMIS , HEPHAESTUS : data analysis for X-ray absorption spectroscopy using IFEFFIT
journal, June 2005


Functionalized Porous Aromatic Framework for Efficient Uranium Adsorption from Aqueous Solutions
journal, March 2017

  • Li, Baiyan; Sun, Qi; Zhang, Yiming
  • ACS Applied Materials & Interfaces, Vol. 9, Issue 14
  • DOI: 10.1021/acsami.7b01711

NMR Studies of Cathode Materials for Lithium-Ion Rechargeable Batteries
journal, October 2004

  • Grey, Clare P.; Dupré, Nicolas
  • Chemical Reviews, Vol. 104, Issue 10
  • DOI: 10.1021/cr020734p

Iron Supplementation Increases Disease Activity and Vitamin E Ameliorates the Effect in Rats with Dextran Sulfate Sodium-Induced Colitis
journal, October 2002

  • Carrier, Julie; Aghdassi, Elaheh; Cullen, Jim
  • The Journal of Nutrition, Vol. 132, Issue 10
  • DOI: 10.1093/jn/131.10.3146

Functionalized Porous Aromatic Frameworks as High‐Performance Adsorbents for the Rapid Removal of Boric Acid from Water
journal, February 2019

  • Kamcev, Jovan; Taylor, Mercedes K.; Shin, Dong‐Myeong
  • Advanced Materials, Vol. 31, Issue 18
  • DOI: 10.1002/adma.201808027

Highly Water-Stable Zirconium Metal–Organic Framework UiO-66 Membranes Supported on Alumina Hollow Fibers for Desalination
journal, June 2015

  • Liu, Xinlei; Demir, Nilay Keser; Wu, Zhentao
  • Journal of the American Chemical Society, Vol. 137, Issue 22
  • DOI: 10.1021/jacs.5b02276

Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems
journal, July 2015

  • Aron, Allegra T.; Ramos-Torres, Karla M.; Cotruvo, Joseph A.
  • Accounts of Chemical Research, Vol. 48, Issue 8
  • DOI: 10.1021/acs.accounts.5b00221

Balancing Acts
journal, April 2004


High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men.
journal, September 1992


Selective binding and removal of guests in a microporous metal–organic framework
journal, December 1995

  • Yaghi, O. M.; Li, Guangming; Li, Hailian
  • Nature, Vol. 378, Issue 6558, p. 703-706
  • DOI: 10.1038/378703a0

Paramagnetic NMR in solution and the solid state
journal, April 2019

  • Pell, Andrew J.; Pintacuda, Guido; Grey, Clare P.
  • Progress in Nuclear Magnetic Resonance Spectroscopy, Vol. 111
  • DOI: 10.1016/j.pnmrs.2018.05.001

Highly porous and stable metal–organic frameworks for uranium extraction
journal, January 2013

  • Carboni, Michaël; Abney, Carter W.; Liu, Shubin
  • Chemical Science, Vol. 4, Issue 6, p. 2396-2402
  • DOI: 10.1039/c3sc50230a

A highly porous metal–organic framework for large organic molecule capture and chromatographic separation
journal, January 2017

  • Li, Pei-Zhou; Su, Jie; Liang, Jie
  • Chemical Communications, Vol. 53, Issue 24
  • DOI: 10.1039/C7CC01063J

Ammonia Capture in Porous Organic Polymers Densely Functionalized with Brønsted Acid Groups
journal, January 2014

  • Van Humbeck, Jeffrey F.; McDonald, Thomas M.; Jing, Xiaofei
  • Journal of the American Chemical Society, Vol. 136, Issue 6, p. 2432-2440
  • DOI: 10.1021/ja4105478

A reactivity-based probe of the intracellular labile ferrous iron pool
journal, July 2016

  • Spangler, Benjamin; Morgan, Charles W.; Fontaine, Shaun D.
  • Nature Chemical Biology, Vol. 12, Issue 9
  • DOI: 10.1038/nchembio.2116

Iron overload enhances the development of experimental liver cirrhosis in mice
journal, April 2003

  • Arezzini, Beatrice; Lunghi, Benedetta; Lungarella, Giuseppe
  • The International Journal of Biochemistry & Cell Biology, Vol. 35, Issue 4
  • DOI: 10.1016/S1357-2725(02)00298-4

Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe
journal, September 2013

  • Au-Yeung, Ho Yu; Chan, Jefferson; Chantarojsiri, Teera
  • Journal of the American Chemical Society, Vol. 135, Issue 40
  • DOI: 10.1021/ja4072964

A turn-on fluorescent probe for detection of hydrogen sulfide in aqueous solution and living cells
journal, January 2014

  • Zhu, Dongjian; Xue, Lin; Li, Guoping
  • Organic Chemistry Frontiers, Vol. 1, Issue 5
  • DOI: 10.1039/c4qo00048j

An investigation of the local iron environment in iron phosphate glasses having different Fe(II) concentrations
journal, August 2002


Escherichia coli Attenuation by Fe Electrocoagulation in Synthetic Bengal Groundwater: Effect of pH and Natural Organic Matter
journal, July 2015

  • Delaire, Caroline; van Genuchten, Case M.; Nelson, Kara L.
  • Environmental Science & Technology, Vol. 49, Issue 16
  • DOI: 10.1021/acs.est.5b01696

Mercury nano-trap for effective and efficient removal of mercury(II) from aqueous solution
journal, November 2014

  • Li, Baiyan; Zhang, Yiming; Ma, Dingxuan
  • Nature Communications, Vol. 5, Issue 1
  • DOI: 10.1038/ncomms6537

The role of iron and reactive oxygen species in cell death
journal, December 2013

  • Dixon, Scott J.; Stockwell, Brent R.
  • Nature Chemical Biology, Vol. 10, Issue 1
  • DOI: 10.1038/nchembio.1416

Applications of water stable metal–organic frameworks
journal, January 2016

  • Wang, Chenghong; Liu, Xinlei; Keser Demir, Nilay
  • Chemical Society Reviews, Vol. 45, Issue 18
  • DOI: 10.1039/C6CS00362A

Synthetic fluorescent sensors for studying the cell biology of metals
journal, February 2008

  • Domaille, Dylan W.; Que, Emily L.; Chang, Christopher J.
  • Nature Chemical Biology, Vol. 4, Issue 3
  • DOI: 10.1038/nchembio.69

In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection
journal, November 2017

  • Aron, Allegra T.; Heffern, Marie C.; Lonergan, Zachery R.
  • Proceedings of the National Academy of Sciences, Vol. 114, Issue 48
  • DOI: 10.1073/pnas.1708747114

Drinking water quality in the Ethiopian section of the East African Rift Valley I—data and health aspects
journal, July 2003


Preparation, characterization and biological activity of Schiff base compounds derived from 8-hydroxyquinoline-2-carboxaldehyde and Jeffamines ED®
journal, May 2002


The role of lysosomes in iron metabolism and recycling
journal, December 2011

  • Kurz, Tino; Eaton, John W.; Brunk, Ulf T.
  • The International Journal of Biochemistry & Cell Biology, Vol. 43, Issue 12
  • DOI: 10.1016/j.biocel.2011.08.016

Contamination of drinking water resources in the Mekong delta floodplains: Arsenic and other trace metals pose serious health risks to population
journal, August 2008


Extraction of Lanthanide and Actinide Ions from Aqueous Mixtures Using a Carboxylic Acid-Functionalized Porous Aromatic Framework
journal, April 2016


A Cryptand Metal-Organic Framework as a Platform for the Selective Uptake and Detection of Group I Metal Cations
journal, January 2017

  • Sapchenko, Sergey A.; Demakov, Pavel A.; Samsonenko, Denis G.
  • Chemistry - A European Journal, Vol. 23, Issue 10
  • DOI: 10.1002/chem.201605895

Highly effective ammonia removal in a series of Brønsted acidic porous polymers: investigation of chemical and structural variations
journal, January 2017

  • Barin, Gokhan; Peterson, Gregory W.; Crocellà, Valentina
  • Chemical Science, Vol. 8, Issue 6
  • DOI: 10.1039/C6SC05079D

Thioether-Based Fluorescent Covalent Organic Framework for Selective Detection and Facile Removal of Mercury(II)
journal, February 2016

  • Ding, San-Yuan; Dong, Ming; Wang, Ya-Wen
  • Journal of the American Chemical Society, Vol. 138, Issue 9
  • DOI: 10.1021/jacs.5b10754

Risks of Copper and Iron Toxicity during Aging in Humans
journal, February 2010

  • Brewer, George J.
  • Chemical Research in Toxicology, Vol. 23, Issue 2
  • DOI: 10.1021/tx900338d

Rapid, Selective Heavy Metal Removal from Water by a Metal–Organic Framework/Polydopamine Composite
journal, March 2018


Targeted Synthesis of a Porous Aromatic Framework with High Stability and Exceptionally High Surface Area
journal, November 2009

  • Ben, Teng; Ren, Hao; Ma, Shengqian
  • Angewandte Chemie International Edition, Vol. 48, Issue 50, p. 9457-9460
  • DOI: 10.1002/anie.200904637

O-TRENSOX, a New Tripodal Iron Chelator Based on 8-Hydroxyquinoline Subunits:  Thermodynamic and Kinetic Studies
journal, August 1997

  • Serratrice, Guy; Boukhalfa, Hakim; Béguin, Claude
  • Inorganic Chemistry, Vol. 36, Issue 18
  • DOI: 10.1021/ic9608096

A naphthalimide–quinoline based probe for selective, fluorescence ratiometric sensing of trivalent ions
journal, January 2013

  • Goswami, Shyamaprosad; Aich, Krishnendu; Das, Avijit Kumar
  • RSC Advances, Vol. 3, Issue 7
  • DOI: 10.1039/c2ra22624c

High-field cross polarization NMR from laser-polarized xenon to a polymer surface
journal, September 1993

  • Long, H. W.; Gaede, H. C.; Shore, J.
  • Journal of the American Chemical Society, Vol. 115, Issue 18
  • DOI: 10.1021/ja00071a086

Activity-based sensing fluorescent probes for iron in biological systems
journal, April 2018

  • Aron, Allegra T.; Reeves, Audrey G.; Chang, Christopher J.
  • Current Opinion in Chemical Biology, Vol. 43
  • DOI: 10.1016/j.cbpa.2017.12.010

Hepatic Iron Overload and Hepatocellular Carcinoma
journal, January 2014


Conjugated Microporous Poly(aryleneethynylene) Networks
journal, September 2007

  • Jiang, Jia-Xing; Su, Fabing; Trewin, Abbie
  • Angewandte Chemie International Edition, Vol. 46, Issue 45
  • DOI: 10.1002/anie.200701595

Vibrational, X-ray absorption, and Mössbauer spectra of sulfate minerals from the weathered massive sulfide deposit at Iron Mountain, California
journal, May 2011


Preparation of Nanofibrous Metal–Organic Framework Filters for Efficient Air Pollution Control
journal, April 2016

  • Zhang, Yuanyuan; Yuan, Shuai; Feng, Xiao
  • Journal of the American Chemical Society, Vol. 138, Issue 18
  • DOI: 10.1021/jacs.6b02553

Iron(III), cobalt(II) and copper(II) complexes bearing 8-quinolinol encapsulated in zeoliteY for the aerobic oxidation of styrene
journal, March 2011

  • Yang, Ying; Ding, Hong; Hao, Shijie
  • Applied Organometallic Chemistry, Vol. 25, Issue 4
  • DOI: 10.1002/aoc.1752

Sulfonate-Grafted Porous Polymer Networks for Preferential CO2 Adsorption at Low Pressure
journal, November 2011

  • Lu, Weigang; Yuan, Daqiang; Sculley, Julian
  • Journal of the American Chemical Society, Vol. 133, Issue 45, p. 18126-18129
  • DOI: 10.1021/ja2087773

Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson’s Disease
journal, June 2016

  • Lee, Sumin; Barin, Gokhan; Ackerman, Cheri M.
  • Journal of the American Chemical Society, Vol. 138, Issue 24
  • DOI: 10.1021/jacs.6b02515

Multiple-scattering calculations of x-ray-absorption spectra
journal, July 1995


Microorganisms pumping iron: anaerobic microbial iron oxidation and reduction
journal, October 2006

  • Weber, Karrie A.; Achenbach, Laurie A.; Coates, John D.
  • Nature Reviews Microbiology, Vol. 4, Issue 10, p. 752-764
  • DOI: 10.1038/nrmicro1490

Occurrence and characteristics of inorganic ions and microorganisms in potable water from Jamaica
journal, July 2010


Metal organic frameworks as adsorbents for dye adsorption: overview, prospects and future challenges
journal, December 2012

  • Adeyemo, Aderonke Ajibola; Adeoye, Idowu Olatunbosun; Bello, Olugbenga Solomon
  • Toxicological & Environmental Chemistry, Vol. 94, Issue 10
  • DOI: 10.1080/02772248.2012.744023

Natural abundance 13C and 15N solid-state NMR analysis of paramagnetic transition-metal cyanide coordination polymers
journal, January 2009

  • Aguiar, Pedro M.; Katz, Michael J.; Leznoff, Daniel B.
  • Physical Chemistry Chemical Physics, Vol. 11, Issue 32
  • DOI: 10.1039/b907747b

Living with Iron (and Oxygen): Questions and Answers about Iron Homeostasis
journal, October 2009

  • Theil, Elizabeth C.; Goss, Dixie J.
  • Chemical Reviews, Vol. 109, Issue 10
  • DOI: 10.1021/cr900052g

Searching for harmony in transition-metal signaling
journal, September 2015


Role of deferiprone in chelation therapy for transfusional iron overload
journal, July 2003


Metal–organic frameworks for the removal of toxic industrial chemicals and chemical warfare agents
journal, January 2017

  • Bobbitt, N. Scott; Mendonca, Matthew L.; Howarth, Ashlee J.
  • Chemical Society Reviews, Vol. 46, Issue 11
  • DOI: 10.1039/C7CS00108H

A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria
journal, January 2013

  • Chen, Yuncong; Zhu, Chengcheng; Yang, Zhenghao
  • Angewandte Chemie International Edition, Vol. 52, Issue 6
  • DOI: 10.1002/anie.201207701

Porous Aromatic Frameworks as a Platform for Multifunctional Applications
journal, February 2019


Polyamine-Tethered Porous Polymer Networks for Carbon Dioxide Capture from Flue Gas
journal, June 2012

  • Lu, Weigang; Sculley, Julian P.; Yuan, Daqiang
  • Angewandte Chemie International Edition, Vol. 51, Issue 30, p. 7480-7484
  • DOI: 10.1002/anie.201202176

Challenges and opportunities in the use of iron in water and wastewater treatment
journal, March 2002


An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells
journal, October 2016

  • Aron, Allegra T.; Loehr, Morten O.; Bogena, Jana
  • Journal of the American Chemical Society, Vol. 138, Issue 43
  • DOI: 10.1021/jacs.6b08016

Electro-chemical arsenic remediation: Field trials in West Bengal
journal, August 2014


Targeted Synthesis of a Porous Aromatic Framework with High Stability and Exceptionally High Surface Area
journal, November 2009


Polyamine-Tethered Porous Polymer Networks for Carbon Dioxide Capture from Flue Gas
journal, June 2012

  • Lu, Weigang; Sculley, Julian P.; Yuan, Daqiang
  • Angewandte Chemie, Vol. 124, Issue 30
  • DOI: 10.1002/ange.201202176

Hepatic iron overload and hepatocellular carcinoma
journal, December 2009


    Works referencing / citing this record:

    Functionalized Porous Aromatic Frameworks as High‐Performance Adsorbents for the Rapid Removal of Boric Acid from Water
    journal, February 2019

    • Kamcev, Jovan; Taylor, Mercedes K.; Shin, Dong‐Myeong
    • Advanced Materials, Vol. 31, Issue 18
    • DOI: 10.1002/adma.201808027

    Conjugated Microporous Poly(aryleneethynylene) Networks
    journal, September 2007

    • Jiang, Jia-Xing; Su, Fabing; Trewin, Abbie
    • Angewandte Chemie International Edition, Vol. 46, Issue 45
    • DOI: 10.1002/anie.200701595

    Targeted Synthesis of a Porous Aromatic Framework with High Stability and Exceptionally High Surface Area
    journal, November 2009

    • Ben, Teng; Ren, Hao; Ma, Shengqian
    • Angewandte Chemie International Edition, Vol. 48, Issue 50, p. 9457-9460
    • DOI: 10.1002/anie.200904637

    Polyamine-Tethered Porous Polymer Networks for Carbon Dioxide Capture from Flue Gas
    journal, June 2012

    • Lu, Weigang; Sculley, Julian P.; Yuan, Daqiang
    • Angewandte Chemie International Edition, Vol. 51, Issue 30, p. 7480-7484
    • DOI: 10.1002/anie.201202176

    A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria
    journal, January 2013

    • Chen, Yuncong; Zhu, Chengcheng; Yang, Zhenghao
    • Angewandte Chemie International Edition, Vol. 52, Issue 6
    • DOI: 10.1002/anie.201207701

    Iron(III), cobalt(II) and copper(II) complexes bearing 8-quinolinol encapsulated in zeoliteY for the aerobic oxidation of styrene
    journal, March 2011

    • Yang, Ying; Ding, Hong; Hao, Shijie
    • Applied Organometallic Chemistry, Vol. 25, Issue 4
    • DOI: 10.1002/aoc.1752

    A Cryptand Metal-Organic Framework as a Platform for the Selective Uptake and Detection of Group I Metal Cations
    journal, January 2017

    • Sapchenko, Sergey A.; Demakov, Pavel A.; Samsonenko, Denis G.
    • Chemistry - A European Journal, Vol. 23, Issue 10
    • DOI: 10.1002/chem.201605895

    Occurrence and characteristics of inorganic ions and microorganisms in potable water from Jamaica
    journal, July 2010


    The role of lysosomes in iron metabolism and recycling
    journal, December 2011

    • Kurz, Tino; Eaton, John W.; Brunk, Ulf T.
    • The International Journal of Biochemistry & Cell Biology, Vol. 43, Issue 12
    • DOI: 10.1016/j.biocel.2011.08.016

    Activity-based sensing fluorescent probes for iron in biological systems
    journal, April 2018

    • Aron, Allegra T.; Reeves, Audrey G.; Chang, Christopher J.
    • Current Opinion in Chemical Biology, Vol. 43
    • DOI: 10.1016/j.cbpa.2017.12.010

    Vibrational, X-ray absorption, and Mössbauer spectra of sulfate minerals from the weathered massive sulfide deposit at Iron Mountain, California
    journal, May 2011


    Contamination of drinking water resources in the Mekong delta floodplains: Arsenic and other trace metals pose serious health risks to population
    journal, August 2008


    Paramagnetic NMR in solution and the solid state
    journal, April 2019

    • Pell, Andrew J.; Pintacuda, Guido; Grey, Clare P.
    • Progress in Nuclear Magnetic Resonance Spectroscopy, Vol. 111
    • DOI: 10.1016/j.pnmrs.2018.05.001

    Electro-chemical arsenic remediation: Field trials in West Bengal
    journal, August 2014


    Preparation, characterization and biological activity of Schiff base compounds derived from 8-hydroxyquinoline-2-carboxaldehyde and Jeffamines ED®
    journal, May 2002


    An investigation of the local iron environment in iron phosphate glasses having different Fe(II) concentrations
    journal, August 2002


    Drinking water quality in the Ethiopian section of the East African Rift Valley I—data and health aspects
    journal, July 2003


    Balancing Acts
    journal, April 2004


    Iron overload enhances the development of experimental liver cirrhosis in mice
    journal, April 2003

    • Arezzini, Beatrice; Lunghi, Benedetta; Lungarella, Giuseppe
    • The International Journal of Biochemistry & Cell Biology, Vol. 35, Issue 4
    • DOI: 10.1016/s1357-2725(02)00298-4

    Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems
    journal, July 2015

    • Aron, Allegra T.; Ramos-Torres, Karla M.; Cotruvo, Joseph A.
    • Accounts of Chemical Research, Vol. 48, Issue 8
    • DOI: 10.1021/acs.accounts.5b00221

    Escherichia coli Attenuation by Fe Electrocoagulation in Synthetic Bengal Groundwater: Effect of pH and Natural Organic Matter
    journal, July 2015

    • Delaire, Caroline; van Genuchten, Case M.; Nelson, Kara L.
    • Environmental Science & Technology, Vol. 49, Issue 16
    • DOI: 10.1021/acs.est.5b01696

    Functionalized Porous Aromatic Framework for Efficient Uranium Adsorption from Aqueous Solutions
    journal, March 2017

    • Li, Baiyan; Sun, Qi; Zhang, Yiming
    • ACS Applied Materials & Interfaces, Vol. 9, Issue 14
    • DOI: 10.1021/acsami.7b01711

    Extraction of Lanthanide and Actinide Ions from Aqueous Mixtures Using a Carboxylic Acid-Functionalized Porous Aromatic Framework
    journal, April 2016


    Rapid, Selective Heavy Metal Removal from Water by a Metal–Organic Framework/Polydopamine Composite
    journal, March 2018


    Porous Aromatic Frameworks as a Platform for Multifunctional Applications
    journal, February 2019


    NMR Studies of Cathode Materials for Lithium-Ion Rechargeable Batteries
    journal, October 2004

    • Grey, Clare P.; Dupré, Nicolas
    • Chemical Reviews, Vol. 104, Issue 10
    • DOI: 10.1021/cr020734p

    Living with Iron (and Oxygen): Questions and Answers about Iron Homeostasis
    journal, October 2009

    • Theil, Elizabeth C.; Goss, Dixie J.
    • Chemical Reviews, Vol. 109, Issue 10
    • DOI: 10.1021/cr900052g

    O-TRENSOX, a New Tripodal Iron Chelator Based on 8-Hydroxyquinoline Subunits:  Thermodynamic and Kinetic Studies
    journal, August 1997

    • Serratrice, Guy; Boukhalfa, Hakim; Béguin, Claude
    • Inorganic Chemistry, Vol. 36, Issue 18
    • DOI: 10.1021/ic9608096

    High-field cross polarization NMR from laser-polarized xenon to a polymer surface
    journal, September 1993

    • Long, H. W.; Gaede, H. C.; Shore, J.
    • Journal of the American Chemical Society, Vol. 115, Issue 18
    • DOI: 10.1021/ja00071a086

    Sulfonate-Grafted Porous Polymer Networks for Preferential CO2 Adsorption at Low Pressure
    journal, November 2011

    • Lu, Weigang; Yuan, Daqiang; Sculley, Julian
    • Journal of the American Chemical Society, Vol. 133, Issue 45, p. 18126-18129
    • DOI: 10.1021/ja2087773

    Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe
    journal, September 2013

    • Au-Yeung, Ho Yu; Chan, Jefferson; Chantarojsiri, Teera
    • Journal of the American Chemical Society, Vol. 135, Issue 40
    • DOI: 10.1021/ja4072964

    Ammonia Capture in Porous Organic Polymers Densely Functionalized with Brønsted Acid Groups
    journal, January 2014

    • Van Humbeck, Jeffrey F.; McDonald, Thomas M.; Jing, Xiaofei
    • Journal of the American Chemical Society, Vol. 136, Issue 6, p. 2432-2440
    • DOI: 10.1021/ja4105478

    Highly Water-Stable Zirconium Metal–Organic Framework UiO-66 Membranes Supported on Alumina Hollow Fibers for Desalination
    journal, June 2015

    • Liu, Xinlei; Demir, Nilay Keser; Wu, Zhentao
    • Journal of the American Chemical Society, Vol. 137, Issue 22
    • DOI: 10.1021/jacs.5b02276

    Thioether-Based Fluorescent Covalent Organic Framework for Selective Detection and Facile Removal of Mercury(II)
    journal, February 2016

    • Ding, San-Yuan; Dong, Ming; Wang, Ya-Wen
    • Journal of the American Chemical Society, Vol. 138, Issue 9
    • DOI: 10.1021/jacs.5b10754

    Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson’s Disease
    journal, June 2016

    • Lee, Sumin; Barin, Gokhan; Ackerman, Cheri M.
    • Journal of the American Chemical Society, Vol. 138, Issue 24
    • DOI: 10.1021/jacs.6b02515

    Preparation of Nanofibrous Metal–Organic Framework Filters for Efficient Air Pollution Control
    journal, April 2016

    • Zhang, Yuanyuan; Yuan, Shuai; Feng, Xiao
    • Journal of the American Chemical Society, Vol. 138, Issue 18
    • DOI: 10.1021/jacs.6b02553

    An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells
    journal, October 2016

    • Aron, Allegra T.; Loehr, Morten O.; Bogena, Jana
    • Journal of the American Chemical Society, Vol. 138, Issue 43
    • DOI: 10.1021/jacs.6b08016

    Risks of Copper and Iron Toxicity during Aging in Humans
    journal, February 2010

    • Brewer, George J.
    • Chemical Research in Toxicology, Vol. 23, Issue 2
    • DOI: 10.1021/tx900338d

    Challenges and opportunities in the use of iron in water and wastewater treatment
    journal, March 2002


    Selective binding and removal of guests in a microporous metal–organic framework
    journal, December 1995

    • Yaghi, O. M.; Li, Guangming; Li, Hailian
    • Nature, Vol. 378, Issue 6558, p. 703-706
    • DOI: 10.1038/378703a0

    The role of iron and reactive oxygen species in cell death
    journal, December 2013

    • Dixon, Scott J.; Stockwell, Brent R.
    • Nature Chemical Biology, Vol. 10, Issue 1
    • DOI: 10.1038/nchembio.1416

    Searching for harmony in transition-metal signaling
    journal, September 2015


    A reactivity-based probe of the intracellular labile ferrous iron pool
    journal, July 2016

    • Spangler, Benjamin; Morgan, Charles W.; Fontaine, Shaun D.
    • Nature Chemical Biology, Vol. 12, Issue 9
    • DOI: 10.1038/nchembio.2116

    Synthetic fluorescent sensors for studying the cell biology of metals
    journal, February 2008

    • Domaille, Dylan W.; Que, Emily L.; Chang, Christopher J.
    • Nature Chemical Biology, Vol. 4, Issue 3
    • DOI: 10.1038/nchembio.69

    Mercury nano-trap for effective and efficient removal of mercury(II) from aqueous solution
    journal, November 2014

    • Li, Baiyan; Zhang, Yiming; Ma, Dingxuan
    • Nature Communications, Vol. 5, Issue 1
    • DOI: 10.1038/ncomms6537

    Microorganisms pumping iron: anaerobic microbial iron oxidation and reduction
    journal, October 2006

    • Weber, Karrie A.; Achenbach, Laurie A.; Coates, John D.
    • Nature Reviews Microbiology, Vol. 4, Issue 10, p. 752-764
    • DOI: 10.1038/nrmicro1490

    Natural abundance 13C and 15N solid-state NMR analysis of paramagnetic transition-metal cyanide coordination polymers
    journal, January 2009

    • Aguiar, Pedro M.; Katz, Michael J.; Leznoff, Daniel B.
    • Physical Chemistry Chemical Physics, Vol. 11, Issue 32
    • DOI: 10.1039/b907747b

    A naphthalimide–quinoline based probe for selective, fluorescence ratiometric sensing of trivalent ions
    journal, January 2013

    • Goswami, Shyamaprosad; Aich, Krishnendu; Das, Avijit Kumar
    • RSC Advances, Vol. 3, Issue 7
    • DOI: 10.1039/c2ra22624c

    Highly porous and stable metal–organic frameworks for uranium extraction
    journal, January 2013

    • Carboni, Michaël; Abney, Carter W.; Liu, Shubin
    • Chemical Science, Vol. 4, Issue 6, p. 2396-2402
    • DOI: 10.1039/c3sc50230a

    A turn-on fluorescent probe for detection of hydrogen sulfide in aqueous solution and living cells
    journal, January 2014

    • Zhu, Dongjian; Xue, Lin; Li, Guoping
    • Organic Chemistry Frontiers, Vol. 1, Issue 5
    • DOI: 10.1039/c4qo00048j

    Applications of water stable metal–organic frameworks
    journal, January 2016

    • Wang, Chenghong; Liu, Xinlei; Keser Demir, Nilay
    • Chemical Society Reviews, Vol. 45, Issue 18
    • DOI: 10.1039/c6cs00362a

    Highly effective ammonia removal in a series of Brønsted acidic porous polymers: investigation of chemical and structural variations
    journal, January 2017

    • Barin, Gokhan; Peterson, Gregory W.; Crocellà, Valentina
    • Chemical Science, Vol. 8, Issue 6
    • DOI: 10.1039/c6sc05079d

    A highly porous metal–organic framework for large organic molecule capture and chromatographic separation
    journal, January 2017

    • Li, Pei-Zhou; Su, Jie; Liang, Jie
    • Chemical Communications, Vol. 53, Issue 24
    • DOI: 10.1039/c7cc01063j

    Metal–organic frameworks for the removal of toxic industrial chemicals and chemical warfare agents
    journal, January 2017

    • Bobbitt, N. Scott; Mendonca, Matthew L.; Howarth, Ashlee J.
    • Chemical Society Reviews, Vol. 46, Issue 11
    • DOI: 10.1039/c7cs00108h

    In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection
    journal, November 2017

    • Aron, Allegra T.; Heffern, Marie C.; Lonergan, Zachery R.
    • Proceedings of the National Academy of Sciences, Vol. 114, Issue 48
    • DOI: 10.1073/pnas.1708747114

    Metal organic frameworks as adsorbents for dye adsorption: overview, prospects and future challenges
    journal, December 2012

    • Adeyemo, Aderonke Ajibola; Adeoye, Idowu Olatunbosun; Bello, Olugbenga Solomon
    • Toxicological & Environmental Chemistry, Vol. 94, Issue 10
    • DOI: 10.1080/02772248.2012.744023

    Iron Supplementation Increases Disease Activity and Vitamin E Ameliorates the Effect in Rats with Dextran Sulfate Sodium-Induced Colitis
    journal, October 2002

    • Carrier, Julie; Aghdassi, Elaheh; Cullen, Jim
    • The Journal of Nutrition, Vol. 132, Issue 10
    • DOI: 10.1093/jn/131.10.3146

    Multiple-scattering calculations of x-ray-absorption spectra
    journal, July 1995


    ATHENA , ARTEMIS , HEPHAESTUS : data analysis for X-ray absorption spectroscopy using IFEFFIT
    journal, June 2005


    Hepatic Iron Overload and Hepatocellular Carcinoma
    journal, January 2014


    High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men.
    journal, September 1992


    Role of deferiprone in chelation therapy for transfusional iron overload
    journal, July 2003